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Identifier: 15644807

GI number: 15644807

Start: 184798

End: 185820

Strand: Reverse

Name: Not Available

Synonym: HP0178

Alternate gene names: NA

Gene position: 185820-184798 (Counterclockwise)

Preceding gene: 15644808

Following gene: 15644803

Centisome position: 11.14

GC content: 39.59

Gene sequence:

>1023_bases
ATGTTACAACCCCCTAAAATTGTCGCTGAATTGAGCGCTAATCATAACCAGGATTTAAACCTAGCCAAAGAAAGCCTTCA
TGCCATTAAGGAAAGCGGTGCGGATTTTGTCAAGCTCCAAACCTACACGCCAAGCTGCATGACTTTAAACTCTAAAGAAG
ATCCTTTCATCATTCAAGGCACTTTATGGGATAAAGAAAATTTGTATGAATTGTATCAAAAGGCTTCTACCCCCCTAGAA
TGGCATGCTGAATTGTTTGAGTTGGCTAGAAAGCTTGATTTAGGCATTTTTAGCTCGCCTTTTAGTTCACAAGCTTTAGA
GCTTTTAGAGAGCCTAAATTGCCCCATGTATAAAATCGCTAGTTTTGAAATCGTTGATTTGGACTTGATTGAAAAGGCCG
CTCGCACACAAAAGCCCATTATCCTTTCTAGCGGTATCGCTACACACACCGAATTGCAAGACGCTATCTCATTGTGCAGA
AGAGTGAATAATTTTGACATCACCCTTTTAAAATGCGTGAGCGCTTATCCCAGTAAAATAGAAGACGCTAACTTGTTGAG
CATGGTTAAATTAGGCGAAATCTTTGGCGTTAAATTTGGCTTGAGCGATCACACGATTGGCTCTCTTTGCCCCATTTTAG
CCACCACTTTAGGAGCGAGCATGATAGAAAAGCATTTCATTTTAAACAAATCCTTACAAACCCCAGACAGCGCTTTTAGC
ATGGATTTTAACGGATTTAAAAGCATGGTTGAAGCCATCAAGCAAAGCGTTTTAGCCTTAGGCGAAGAAGAGCCAAGAAT
CAATCCAAAGACTTTAGAAAAGCGAAGATTTTTTGCACGCTCTTTATTTGTTATTAAGGATATTCAAAAAGGCGAAGCAT
TGACTGAAAACAATATCAAAGCCTTACGCCCCAACCTTGGCTTACACCCTAAATTTTATAAAGAAATTTTAGGCCAAAAA
GCATCAAAATTCTTAAAAGCCAACACCCCCTTAAGCGCTGATGATATAGAACGCTCATTGTAG

Upstream 100 bases:

>100_bases
AGGGGCGTTAGTTTTAGCCACGCATGATGAGCATTTGGCTTTCACTTGCTCTCAAGTCTATCGCTTAGAAAAAGAAGTTT
TGATTAAGGAGAAATAAGAA

Downstream 100 bases:

>100_bases
GTTCGTTTTGATCAAAAAATGGGGTTTTTAATTTTGTTTTATGGTTTTAGATTTGATTTTAAACTCATTTTCTTTATTTT
AAACTCTTAAGGGGACAGGG

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLQPPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYELYQKASTPLE
WHAELFELARKLDLGIFSSPFSSQALELLESLNCPMYKIASFEIVDLDLIEKAARTQKPIILSSGIATHTELQDAISLCR
RVNNFDITLLKCVSAYPSKIEDANLLSMVKLGEIFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
MDFNGFKSMVEAIKQSVLALGEEEPRINPKTLEKRRFFARSLFVIKDIQKGEALTENNIKALRPNLGLHPKFYKEILGQK
ASKFLKANTPLSADDIERSL

Sequences:

>Translated_340_residues
MLQPPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYELYQKASTPLE
WHAELFELARKLDLGIFSSPFSSQALELLESLNCPMYKIASFEIVDLDLIEKAARTQKPIILSSGIATHTELQDAISLCR
RVNNFDITLLKCVSAYPSKIEDANLLSMVKLGEIFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
MDFNGFKSMVEAIKQSVLALGEEEPRINPKTLEKRRFFARSLFVIKDIQKGEALTENNIKALRPNLGLHPKFYKEILGQK
ASKFLKANTPLSADDIERSL
>Mature_340_residues
MLQPPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYELYQKASTPLE
WHAELFELARKLDLGIFSSPFSSQALELLESLNCPMYKIASFEIVDLDLIEKAARTQKPIILSSGIATHTELQDAISLCR
RVNNFDITLLKCVSAYPSKIEDANLLSMVKLGEIFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
MDFNGFKSMVEAIKQSVLALGEEEPRINPKTLEKRRFFARSLFVIKDIQKGEALTENNIKALRPNLGLHPKFYKEILGQK
ASKFLKANTPLSADDIERSL

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=329, Percent_Identity=28.2674772036474, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357081, Length=360, Percent_Identity=25.5555555555556, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38007; Mature: 38007

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQPPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQG
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TLWDKENLYELYQKASTPLEWHAELFELARKLDLGIFSSPFSSQALELLESLNCPMYKIA
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEC
SFEIVDLDLIEKAARTQKPIILSSGIATHTELQDAISLCRRVNNFDITLLKCVSAYPSKI
CEEEEHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
EDANLLSMVKLGEIFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
CCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
MDFNGFKSMVEAIKQSVLALGEEEPRINPKTLEKRRFFARSLFVIKDIQKGEALTENNIK
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALRPNLGLHPKFYKEILGQKASKFLKANTPLSADDIERSL
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
>Mature Secondary Structure
MLQPPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQG
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TLWDKENLYELYQKASTPLEWHAELFELARKLDLGIFSSPFSSQALELLESLNCPMYKIA
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEC
SFEIVDLDLIEKAARTQKPIILSSGIATHTELQDAISLCRRVNNFDITLLKCVSAYPSKI
CEEEEHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
EDANLLSMVKLGEIFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
CCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
MDFNGFKSMVEAIKQSVLALGEEEPRINPKTLEKRRFFARSLFVIKDIQKGEALTENNIK
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALRPNLGLHPKFYKEILGQKASKFLKANTPLSADDIERSL
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]