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Identifier: 15644712

GI number: 15644712

Start: 86656

End: 88677

Strand: Reverse

Name: Not Available

Synonym: HP0082

Alternate gene names: 15644712

Gene position: 88677-86656 (Counterclockwise)

Preceding gene: 15644713

Following gene: 15644705

Centisome position: 5.32

GC content: 39.17

Gene sequence:

>2022_bases
ATGAAATCTACAAGAATTGGTTCTAAAATTGTCATGATGGTGTGTGCGGTTGTTATTGTCATTAGTGCTGTTATGGGCGT
TATTATCAGCTACAAGGTTGAAAGCGTGTTGCAAAGCCAAGCCACAGAATTGCTGCAAAAAAAAGCTCAGTTAGTCAGTT
TTAAAATTCAAGGCATTATGAAGCGCATTTTTATGGGCGCTAACACCCTTGAAAAATTTTTAAGCGATGAAAATAGCGCT
ATCAACGACACCCTAAAAAGACGCATGCTCTCTGAGTTTTTGTTAGCAAACCCTCATGTGTTATTGGTTAGCGCGATTTA
TACGAATAATAATGAACGAGTCATCACTGCCATGAGCATGGATTCAAAAATCGCCTACCCTAATACCACGCTCAATGAAA
ACATGACCAATCAAATCCGTTCGCTCAAAAGTATAACCCATTCAGATCCCTATTATAAAGAGGTTAATGGCGATAAAATC
TATGGCATGGATATTACCCTCCCCCTAATGGGTAAGAATCAAAATGCTATAGGCGCGCTGAATTTCTTTTTAAACATTGA
CGCTTTTTATACCGATGTGGTAGGCAAGAAAAAGAGCAACACCTTTTTAATGGGGAAAGACGGCAGGCTTTTAATCAACC
CTAATCGTGAGATCCAAGATAAGATTTTAAGCGCTATCAATCCGGATAGAAGAGTCGCTAAAGCTGTGGAGTATTACAAT
CAAAACGAAGCGGGCACTTTGAGCTACCATTCATTGAGCGGGAATACAGAAACCTTTTTAGCCATACAGCCCTTTGATTT
TTTTGAAGAAAAAGGGAATAACGGCAATCATTGGCGTTGGGCAATTGGGAAATATGTCAATAAATCTTTAGTCTTTAAAG
AAGCGACAAACACCAAATTCATTATTATCACCACTTTGATTTTAGGCGTGCTGGTGTTAGCCTTTTTAGTCTTTATCATC
GTTTCCAATCTCATAACCAAACGCATCAGTAGGGTCAATAACACCCTAAATGATTTTTTCAACTTGCTTAATAACCCCAA
AAATAACCATGCCATAAGCCTAACGCCCCCAAGCGCTTATGATGAAATCGGGCAAATGCAAGCTTCTATCAATGAAAACA
TTCTTAAAACCCAAGAAAGCATTCAAGCCGATAACAAAGCCATTCAAAACAGCATTGAAGTAACAAATTATGTGGAAAAT
GGGGATTTCACGCAAGAAATCGCATGCGTGCCTAAAAATAAAGATTTGCAAGCTTTAAGAAATACGATTAATAGCATTAT
TCAGTATTTTCGCAACCAAATTGGCGCCAATATTGAATCCCTAAACAACGCCCTAGAGCATTATAAAAACCTGGATTTCA
CCCACCACATCCAAAATCCTAAAGCCAACATGGAAAAAGCGCTCAACACTTTAGGGCAAGAAATTTCTAGCATGCTTAAA
GCTTCTTTAGGGTTTGCGAACGCGCTCAATCATGAATCCAAAGATTTAAAAACTTGCGTGGATAACTTGACTAAAACCGC
CCACAAACAAGAAAGGAGTCTGAAAAACACCACTCAATCCTTAGAAGAAATCACTAATATTATCACAACCATTGATTCTA
AAAGCCAAGAGATGATCTCTCAAGGCGAAGACATTAAAAGCGTGGTGGATATGATTAGAGACATCGCTGATCAAACCAAT
CTTTTAGCCCTAAACGCCGCTATTGAAGCCGCAAGGGCTGGCGAGCATGGCAGAGGCTTTGCGGTGGTGGCTGATGAGGT
GAGGAAGCTCGCTGAAAGGACGCAAAAATCCCTCAGCGAAATTGAAGCCAATATTAATATTCTAGTTCAAAGCATTGCCG
ATAACGCTGAGTCTATCAAAATGCAAAATAAGGGCGTAGAAAATATCCACAACTCCATTAACGCCTTGCAACAAGATGTG
CAGGATAATTTGACTATCGCTAATCATTCTTTACAAGTCAGCACTAAAATTGATGGGATCTCCCAAGATATTTTAGAAGA
TGTGAGCAGGAAGAAATTTTGA

Upstream 100 bases:

>100_bases
TTTTATTTTCTGCTTTTTTTGTCCTCTCTTGTTTTATTAAAATTTCAAAATAATGTATAATAATCGTTCTCTATCAATTC
GTTTTAAAAGGGCAAATGGA

Downstream 100 bases:

>100_bases
TTTCTGCCTTTAATTTTGAGCGTCTAAAATATAAAACCGCCTAAAGCAAGGGGCTTTCGCCCTAACGAACGCTAATATAA
AAGGCTCTTTAAAGGGGTAT

Product: methyl-accepting chemotaxis transducer (tlpC)

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MKSTRIGSKIVMMVCAVVIVISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQGIMKRIFMGANTLEKFLSDENSA
INDTLKRRMLSEFLLANPHVLLVSAIYTNNNERVITAMSMDSKIAYPNTTLNENMTNQIRSLKSITHSDPYYKEVNGDKI
YGMDITLPLMGKNQNAIGALNFFLNIDAFYTDVVGKKKSNTFLMGKDGRLLINPNREIQDKILSAINPDRRVAKAVEYYN
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGNNGNHWRWAIGKYVNKSLVFKEATNTKFIIITTLILGVLVLAFLVFII
VSNLITKRISRVNNTLNDFFNLLNNPKNNHAISLTPPSAYDEIGQMQASINENILKTQESIQADNKAIQNSIEVTNYVEN
GDFTQEIACVPKNKDLQALRNTINSIIQYFRNQIGANIESLNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMISQGEDIKSVVDMIRDIADQTN
LLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDV
QDNLTIANHSLQVSTKIDGISQDILEDVSRKKF

Sequences:

>Translated_673_residues
MKSTRIGSKIVMMVCAVVIVISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQGIMKRIFMGANTLEKFLSDENSA
INDTLKRRMLSEFLLANPHVLLVSAIYTNNNERVITAMSMDSKIAYPNTTLNENMTNQIRSLKSITHSDPYYKEVNGDKI
YGMDITLPLMGKNQNAIGALNFFLNIDAFYTDVVGKKKSNTFLMGKDGRLLINPNREIQDKILSAINPDRRVAKAVEYYN
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGNNGNHWRWAIGKYVNKSLVFKEATNTKFIIITTLILGVLVLAFLVFII
VSNLITKRISRVNNTLNDFFNLLNNPKNNHAISLTPPSAYDEIGQMQASINENILKTQESIQADNKAIQNSIEVTNYVEN
GDFTQEIACVPKNKDLQALRNTINSIIQYFRNQIGANIESLNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMISQGEDIKSVVDMIRDIADQTN
LLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDV
QDNLTIANHSLQVSTKIDGISQDILEDVSRKKF
>Mature_673_residues
MKSTRIGSKIVMMVCAVVIVISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQGIMKRIFMGANTLEKFLSDENSA
INDTLKRRMLSEFLLANPHVLLVSAIYTNNNERVITAMSMDSKIAYPNTTLNENMTNQIRSLKSITHSDPYYKEVNGDKI
YGMDITLPLMGKNQNAIGALNFFLNIDAFYTDVVGKKKSNTFLMGKDGRLLINPNREIQDKILSAINPDRRVAKAVEYYN
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGNNGNHWRWAIGKYVNKSLVFKEATNTKFIIITTLILGVLVLAFLVFII
VSNLITKRISRVNNTLNDFFNLLNNPKNNHAISLTPPSAYDEIGQMQASINENILKTQESIQADNKAIQNSIEVTNYVEN
GDFTQEIACVPKNKDLQALRNTINSIIQYFRNQIGANIESLNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMISQGEDIKSVVDMIRDIADQTN
LLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDV
QDNLTIANHSLQVSTKIDGISQDILEDVSRKKF

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Integral Membrane. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=206, Percent_Identity=30.5825242718447, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787690, Length=293, Percent_Identity=27.3037542662116, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788195, Length=281, Percent_Identity=28.8256227758007, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI2367378, Length=202, Percent_Identity=29.7029702970297, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788194, Length=147, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 75215; Mature: 75215

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTRIGSKIVMMVCAVVIVISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQGIM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIFMGANTLEKFLSDENSAINDTLKRRMLSEFLLANPHVLLVSAIYTNNNERVITAMSM
HHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEEC
DSKIAYPNTTLNENMTNQIRSLKSITHSDPYYKEVNGDKIYGMDITLPLMGKNQNAIGAL
CCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEEEEEECCCCCCCHHHH
NFFLNIDAFYTDVVGKKKSNTFLMGKDGRLLINPNREIQDKILSAINPDRRVAKAVEYYN
HHHEEHHHHHHHHHCCCCCCEEEEECCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHC
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGNNGNHWRWAIGKYVNKSLVFKEATNTKF
CCCCCCEEEEEECCCCCEEEEECCHHHHHHCCCCCCEEEEHHHHHHCHHHEEEECCCCCE
IIITTLILGVLVLAFLVFIIVSNLITKRISRVNNTLNDFFNLLNNPKNNHAISLTPPSAY
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHH
DEIGQMQASINENILKTQESIQADNKAIQNSIEVTNYVENGDFTQEIACVPKNKDLQALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHEECCCCCCHHHHH
NTINSIIQYFRNQIGANIESLNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMIS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QGEDIKSVVDMIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSE
CCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHH
IEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDVQDNLTIANHSLQVSTKIDGI
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCH
SQDILEDVSRKKF
HHHHHHHHHHCCC
>Mature Secondary Structure
MKSTRIGSKIVMMVCAVVIVISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQGIM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIFMGANTLEKFLSDENSAINDTLKRRMLSEFLLANPHVLLVSAIYTNNNERVITAMSM
HHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEEC
DSKIAYPNTTLNENMTNQIRSLKSITHSDPYYKEVNGDKIYGMDITLPLMGKNQNAIGAL
CCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEEEEEECCCCCCCHHHH
NFFLNIDAFYTDVVGKKKSNTFLMGKDGRLLINPNREIQDKILSAINPDRRVAKAVEYYN
HHHEEHHHHHHHHHCCCCCCEEEEECCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHC
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGNNGNHWRWAIGKYVNKSLVFKEATNTKF
CCCCCCEEEEEECCCCCEEEEECCHHHHHHCCCCCCEEEEHHHHHHCHHHEEEECCCCCE
IIITTLILGVLVLAFLVFIIVSNLITKRISRVNNTLNDFFNLLNNPKNNHAISLTPPSAY
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHH
DEIGQMQASINENILKTQESIQADNKAIQNSIEVTNYVENGDFTQEIACVPKNKDLQALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHEECCCCCCHHHHH
NTINSIIQYFRNQIGANIESLNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMIS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QGEDIKSVVDMIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSE
CCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHH
IEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDVQDNLTIANHSLQVSTKIDGI
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCH
SQDILEDVSRKKF
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]