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The map label for this gene is lspA

Identifier: 15644704

GI number: 15644704

Start: 78302

End: 78775

Strand: Reverse

Name: lspA

Synonym: HP0074

Alternate gene names: 15644704

Gene position: 78775-78302 (Counterclockwise)

Preceding gene: 15644705

Following gene: 15644703

Centisome position: 4.72

GC content: 36.92

Gene sequence:

>474_bases
GTGCTAAAAACCACTAAAAAAAGCCTGTTGGTTTTTATGGGGGTTTTTTTCCTTATTTTTGGCGTGGATCAAGCGATTAA
ATACGCTATTTTAGAAGGGTTTCGCTATGAAAGTTTGATGATAGATATTGTTTTAGTGTTCAATAAAGGCGTGGCGTTTT
CCTTGCTCAGTTTTTTAGAGGGGGGTTTGAAATACTTGCAAATCCTTTTGATTTTAGGGCTTTTTATCTTTTTAATGCGC
CAAAGGGAGCTTTTTAAAAACCATGCGATAGAGTTTGGCATGGTGTTTGGCGCCGGGGTTTCTAATGTTTTAGACCGGTT
TGTGCATGGGGGCGTGGTGGATTATGTGTATTATCATTATGGCTTTGATTTTGCCATTTTTAATTTCGCTGATGTCATGA
TAGATGTGGGCGTGGGCGTTTTATTGTTGAAACAATTCTTTTTTAAGCAAAAACAAAACAAAATTAAGGCATAA

Upstream 100 bases:

>100_bases
GCGGCACTGAAAACAAATTGCGAATCCTTTTAGAAGCTAAAGATGAAAAGCTTTTAGAATCCAAAATGCAAGAATTAAAA
GAGTTTTTTGAAGGGCATTT

Downstream 100 bases:

>100_bases
TCACTCTTTTTAAAATGAAAGGTCGCGTAGCTCAGTTGGTAGAGCACTACCTTGACATGGTAGTGGCCGCTGGTTCAAGT
CCAGTCGTGGCCACCATTAT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MLKTTKKSLLVFMGVFFLIFGVDQAIKYAILEGFRYESLMIDIVLVFNKGVAFSLLSFLEGGLKYLQILLILGLFIFLMR
QRELFKNHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLLKQFFFKQKQNKIKA

Sequences:

>Translated_157_residues
MLKTTKKSLLVFMGVFFLIFGVDQAIKYAILEGFRYESLMIDIVLVFNKGVAFSLLSFLEGGLKYLQILLILGLFIFLMR
QRELFKNHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLLKQFFFKQKQNKIKA
>Mature_157_residues
MLKTTKKSLLVFMGVFFLIFGVDQAIKYAILEGFRYESLMIDIVLVFNKGVAFSLLSFLEGGLKYLQILLILGLFIFLMR
QRELFKNHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLLKQFFFKQKQNKIKA

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17998; Mature: 17998

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTTKKSLLVFMGVFFLIFGVDQAIKYAILEGFRYESLMIDIVLVFNKGVAFSLLSFLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
GGLKYLQILLILGLFIFLMRQRELFKNHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHH
GFDFAIFNFADVMIDVGVGVLLLKQFFFKQKQNKIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKTTKKSLLVFMGVFFLIFGVDQAIKYAILEGFRYESLMIDIVLVFNKGVAFSLLSFLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
GGLKYLQILLILGLFIFLMRQRELFKNHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHH
GFDFAIFNFADVMIDVGVGVLLLKQFFFKQKQNKIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]