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The map label for this gene is ktrA

Identifier: 13508200

GI number: 13508200

Start: 564390

End: 565085

Strand: Direct

Name: ktrA

Synonym: MPN461

Alternate gene names: NA

Gene position: 564390-565085 (Clockwise)

Preceding gene: 13508184

Following gene: 13508201

Centisome position: 69.13

GC content: 42.53

Gene sequence:

>696_bases
ATGAAACGTGCCGATTTTTGCATTATTGGCCTTGGTAGGTTTGGGATGCAAGTAGCACATTCTTTAAAAGAGAACAACTT
TACCCTGGTTTTGATCGATAATGATCAACACAAAACCAATACTGCTGCCCAGGAATTTGACCATGTAGTGTGTTGTGATG
GGAGTAACTTAACGGCGTTAGCTGAGCTCCAACTAGAGGAGTTTTCGGCAGTCATAGTTGGGGTAACTAACATAGAAGCG
AGCATTATGATTTGTGCTAACCTTCGGGAATTGGGTCAAAAAAACATTATTGCCCGTGCTAAAAACGAAGTGCATAACCG
GGTGTTACGTACTATGGGTATTAGGGAAGCTTTGATCCCGGAAAAGATTGTCGGCAAGAACCTTGTCATTCGTTTAATTC
ACGGCATGGAAACCGAAATTATTAACCTTGGCAATGACATCCTCTTTGTTCGCGCTCCGGTGAACAACAAGAAGCTCTTT
AATCGTACGTTGGGGGAAATTAACATCCGTGAACACACGAATGCTAACCTCATCTCAATTATGCGGAATGGCAAAGATGT
CGTCTTTCCTTTGGGTCCGAATACCCAGATTCAACCAGGGGATGTAATTACAGCCGTGTGTCAATTAAGTGGCGTGAACC
AGTATTTGCGCTACATTAATCCTAACGACAAGAATAAGTACAAAGCGAGTGAATAA

Upstream 100 bases:

>100_bases
GTCACCCCACAGGATTAGTTTTAACCAAGCGAGTAGTTTAGCTTTCTGTTTATGAGCAGCTGTCATGTAAATGACAATAT
AAATATAATTTTACCAGCAT

Downstream 100 bases:

>100_bases
TTAGATCACCCAAGACCCCTCCAATCCTTATCGGTTTGCCGTTTTACTCGTGCCGCGCAGCGTGGTGTACTATGAGCAGT
TGCAAAGGGGATTAGCGCTC

Product: KtrA, K+ Na+ uptake

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKRADFCIIGLGRFGMQVAHSLKENNFTLVLIDNDQHKTNTAAQEFDHVVCCDGSNLTALAELQLEEFSAVIVGVTNIEA
SIMICANLRELGQKNIIARAKNEVHNRVLRTMGIREALIPEKIVGKNLVIRLIHGMETEIINLGNDILFVRAPVNNKKLF
NRTLGEINIREHTNANLISIMRNGKDVVFPLGPNTQIQPGDVITAVCQLSGVNQYLRYINPNDKNKYKASE

Sequences:

>Translated_231_residues
MKRADFCIIGLGRFGMQVAHSLKENNFTLVLIDNDQHKTNTAAQEFDHVVCCDGSNLTALAELQLEEFSAVIVGVTNIEA
SIMICANLRELGQKNIIARAKNEVHNRVLRTMGIREALIPEKIVGKNLVIRLIHGMETEIINLGNDILFVRAPVNNKKLF
NRTLGEINIREHTNANLISIMRNGKDVVFPLGPNTQIQPGDVITAVCQLSGVNQYLRYINPNDKNKYKASE
>Mature_231_residues
MKRADFCIIGLGRFGMQVAHSLKENNFTLVLIDNDQHKTNTAAQEFDHVVCCDGSNLTALAELQLEEFSAVIVGVTNIEA
SIMICANLRELGQKNIIARAKNEVHNRVLRTMGIREALIPEKIVGKNLVIRLIHGMETEIINLGNDILFVRAPVNNKKLF
NRTLGEINIREHTNANLISIMRNGKDVVFPLGPNTQIQPGDVITAVCQLSGVNQYLRYINPNDKNKYKASE

Specific function: Unknown

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y461_MYCPN (P75322)

Other databases:

- EMBL:   U00089
- PIR:   S73706
- RefSeq:   NP_110149.1
- ProteinModelPortal:   P75322
- IntAct:   P75322
- GeneID:   877150
- GenomeReviews:   U00089_GR
- KEGG:   mpn:MPN461
- HOGENOM:   HBG571685
- OMA:   YVVEIHI
- ProtClustDB:   CLSK335279
- BioCyc:   MPNE272634:MPN461-MONOMER
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N

EC number: NA

Molecular weight: Translated: 25773; Mature: 25773

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS51202 RCK_C; PS51201 RCK_N

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRADFCIIGLGRFGMQVAHSLKENNFTLVLIDNDQHKTNTAAQEFDHVVCCDGSNLTAL
CCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCCEEEEECCCCCEEE
AELQLEEFSAVIVGVTNIEASIMICANLRELGQKNIIARAKNEVHNRVLRTMGIREALIP
EEEEHHHCEEEEEEEECCCEEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHCC
EKIVGKNLVIRLIHGMETEIINLGNDILFVRAPVNNKKLFNRTLGEINIREHTNANLISI
HHHHCCHHHHHHHHCCCEEEEECCCCEEEEECCCCCHHHHHHHHCCEEEECCCCCCEEEE
MRNGKDVVFPLGPNTQIQPGDVITAVCQLSGVNQYLRYINPNDKNKYKASE
EECCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKRADFCIIGLGRFGMQVAHSLKENNFTLVLIDNDQHKTNTAAQEFDHVVCCDGSNLTAL
CCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCCEEEEECCCCCEEE
AELQLEEFSAVIVGVTNIEASIMICANLRELGQKNIIARAKNEVHNRVLRTMGIREALIP
EEEEHHHCEEEEEEEECCCEEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHCC
EKIVGKNLVIRLIHGMETEIINLGNDILFVRAPVNNKKLFNRTLGEINIREHTNANLISI
HHHHCCHHHHHHHHCCCEEEEECCCCEEEEECCCCCHHHHHHHHCCEEEECCCCCCEEEE
MRNGKDVVFPLGPNTQIQPGDVITAVCQLSGVNQYLRYINPNDKNKYKASE
EECCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633