| Definition | Mycoplasma pneumoniae M129, complete genome. |
|---|---|
| Accession | NC_000912 |
| Length | 816,394 |
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The map label for this gene is dnaE [H]
Identifier: 13508117
GI number: 13508117
Start: 453650
End: 456268
Strand: Direct
Name: dnaE [H]
Synonym: MPN378
Alternate gene names: 13508117
Gene position: 453650-456268 (Clockwise)
Preceding gene: 13508116
Following gene: 13508118
Centisome position: 55.57
GC content: 39.82
Gene sequence:
>2619_bases ATGTTTGTTAACCTCCACACTAACTCTTACTATAACTTCCTCAACTCCACACTTTCACCGCAAAAGCTAGTTGACCTAGC TGTTCAAGACCAACAGGTAGCTGTTTGTTTAACCGATCCCAACTTATTTGGTGCTACCGAGTTTTTTTTGGCCTGTCAAA AAGCGCACATTAAACCCTTAATTGGGTTGAGTGTTACTGTTCGACATTACGAACAAAACGTTAATTTACTAGTAATTGCC CAAACCAACCGGGGTTATCAGAACCTAATGTGCTTAGCGTTAGTTAAAGACCAACCAGATTTGCAATTAGAACCCTTTTT GGATGGTAATGTGGTAATTATTTGCACACAAACTGAACTGCGCCTCAACACCGCAAACCCCGTTTACTTAGCACATGGTT TGAGTGGTCGTTATCCTAAAATTGCAGTAACACAAAAACCAGTTAAGTGTCAAAACACCAATAAGGACTTAACACTGCTC TTAACACTTAAGCAAATTAGTCAAATTAACAGCGAACACTTCCAGCCACTGGAATGAAAATTAAGCCGTAGTTTAAACGA AATCCAATTGGATCCACCATTGTTGCAACAACTCCGGCACCAACCTTTTTTAAGCCAAAAGGCAGCACAGCAAATTTTTA GCGAAGAGGAATTGGGAAATCTGCAAAAGCTAGTGGAGCAAAGTCAATGAGATTTAACCAAACTCAAAGCGTCATCGTTA CAAGTGTCACACAACGATGCACAAATGTTAAGCGAGCAGTGTCAACTAGCCTTAACTGAATTTTTAAAGCTCAATCCGCA ATTAAACAAACAGCTCTATGAAGAGCGGTTAGCCAAAGAATTGGAGATAATTAACTCACTCCACTTTGCTAGTTACTTTT TAGTGGTGAGCGACTTAGTTCAGTTTGCCCATAATAACGATATCCTCATCGGTCCTGGTCGAGGATCTGCAGTGGGTTCT TTAGTGGCCTTTCTGCTCAAAATTACCCAAATTGATCCAGTAGCCAACAATCTCATTTTTGAGCGCTTTATTTCCCGTCA CCGCCAGGGCTTACCTGACATTGACATTGACATTATGGAAACTAAACGTGATTTAGTAATTGACTATGTCATGCAAAAAT ATGGCCGGGAACAGTGTGCACAAATAGTTACTTTCCAAAAATTTAAGACCCGCTCTGCGTTGCGTGATGTCGGTAAGGTA TTTAACCACATTGAGGGTGCTGAAGATTTACTGGGTAAACTACCAAAAGACAAAAGCTTATTGGAGCTTGATGTAAACGG TGTTACTGATCCGGTTTTACAACTTAGTTTAAAGAGCTTTCGCTTGTTGTGGGAGGTGGCGCGTGAAATTATTAACTTTC CGCGCCAACCAAGCATTCACGCTTCTGGTGTTGTGATTGTCACTGAACCTTTAATTACCACGATCCCTTTAATGGTGGGT AATAACAACAACTACGTCACCCAAGTGTCGATGGACTGGTTAGAATGGTACAACCTCAATAAGTTTGACTTATTGGGTTT AATTAACCTCACCATGATCCATGAGGTTGTGCAAGCGGTAAAACCCAAGGAAGTTAGCGTACAGCAATTCCTCCAACAAA TACCGCTAGATGATGAAGCTACTTTTACTAACCTCACTAACCAAGCCACTTTAGGTGTTTTTCAACTAGAGTCGTTTGGG ATGAAAAAGGTGCTCAAACAAATTAAACCGCACAACCTCCATGATTTAGCAATTGTTTTAGCACTTTACCGCCCCGGTCC ACAGGACAACATTAATACCTTTATTGCTAACCGTAACTTAGGGTTTGACACATCAGACATCGATCCGCGAATTTTGCCAA TCCTCAAAGAAACTTACGGAGTGTTAATCTTTCAAGAACAGGTTATTAACATCGCCAAAACTGTTGCTAACTATTCATTG GAAACCGCTGATAGCTTTCGCCGTGCCATTTCCAAAAAAAACTTGCAAGTAATTCAGGACAACATGCGCAGCTTTTATGA AGGCGCGCTAGCCAATAACTTTAGCTTAAAAGCAGCGACTACTATCTTTAATTACATCCAGCGCTTTGCTGGATATGGTT TTAACTTGTCCCACGCCTTGGGCTATGCTTTATTGAGTTACTGAACAGCATGATTGAAGACACATTACTTTGAGCAATTT AACCTGTGGTGATTAAACCACGAACAGGGCAAAAAGGAAAAGCAAAAACAGCTCTTAAACGAGTTTATTAGCAGTGGTTA TGAAATTTGCCCACCACTAATCAATAAGGCTAAAAGTGATTTTAGTGTTCAAGATAAAAAGCTGTATTTAGGCTTTAAGT TAATCAATGGTATTGGTGACAAGCAAGCCCATGCCTTGGAACATGTTCAGGAAGTTTTAAAGCAAAACCCCAATTTATCC TTAATAGCTACCGTTAATTTGTGTTTGAGCAAAACGGTAGGGGGTTTAGAACTTAAAGACATTACATTGCTCCAACAAGC AGGTTGTTTTAATTGCTTTAATTACACGGTTGACTTTAATTTGGCCAAAAGCTTTTGGGTGCAAAGTAACCATGAATTAT TTCCAAAAATACCACTAGATCAACCACCCGTAATTAACTGAAAGAGCTTTGGTTTTTAA
Upstream 100 bases:
>100_bases GAAAAAAGAATTGGAAAACACCTTTGAGCCACGTACCAGAATTGAAATTAAACGTGAAATCAAAGAGTTGGAACGTAAAC TAAGAAGGAACCGTTAGTGA
Downstream 100 bases:
>100_bases TTTATGAAAAATGCAATTTTAATTGATGGTAACTCACTAGCCTACCGTGCTTACTTCGCTACTTGACAACAGGTGGAGTT TGCCAAACTACACAACTTAC
Product: DNA polymerase III subunit alpha
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 872; Mature: 872
Protein sequence:
>872_residues MFVNLHTNSYYNFLNSTLSPQKLVDLAVQDQQVAVCLTDPNLFGATEFFLACQKAHIKPLIGLSVTVRHYEQNVNLLVIA QTNRGYQNLMCLALVKDQPDLQLEPFLDGNVVIICTQTELRLNTANPVYLAHGLSGRYPKIAVTQKPVKCQNTNKDLTLL LTLKQISQINSEHFQPLEWKLSRSLNEIQLDPPLLQQLRHQPFLSQKAAQQIFSEEELGNLQKLVEQSQWDLTKLKASSL QVSHNDAQMLSEQCQLALTEFLKLNPQLNKQLYEERLAKELEIINSLHFASYFLVVSDLVQFAHNNDILIGPGRGSAVGS LVAFLLKITQIDPVANNLIFERFISRHRQGLPDIDIDIMETKRDLVIDYVMQKYGREQCAQIVTFQKFKTRSALRDVGKV FNHIEGAEDLLGKLPKDKSLLELDVNGVTDPVLQLSLKSFRLLWEVAREIINFPRQPSIHASGVVIVTEPLITTIPLMVG NNNNYVTQVSMDWLEWYNLNKFDLLGLINLTMIHEVVQAVKPKEVSVQQFLQQIPLDDEATFTNLTNQATLGVFQLESFG MKKVLKQIKPHNLHDLAIVLALYRPGPQDNINTFIANRNLGFDTSDIDPRILPILKETYGVLIFQEQVINIAKTVANYSL ETADSFRRAISKKNLQVIQDNMRSFYEGALANNFSLKAATTIFNYIQRFAGYGFNLSHALGYALLSYWTAWLKTHYFEQF NLWWLNHEQGKKEKQKQLLNEFISSGYEICPPLINKAKSDFSVQDKKLYLGFKLINGIGDKQAHALEHVQEVLKQNPNLS LIATVNLCLSKTVGGLELKDITLLQQAGCFNCFNYTVDFNLAKSFWVQSNHELFPKIPLDQPPVINWKSFGF
Sequences:
>Translated_872_residues MFVNLHTNSYYNFLNSTLSPQKLVDLAVQDQQVAVCLTDPNLFGATEFFLACQKAHIKPLIGLSVTVRHYEQNVNLLVIA QTNRGYQNLMCLALVKDQPDLQLEPFLDGNVVIICTQTELRLNTANPVYLAHGLSGRYPKIAVTQKPVKCQNTNKDLTLL LTLKQISQINSEHFQPLE*KLSRSLNEIQLDPPLLQQLRHQPFLSQKAAQQIFSEEELGNLQKLVEQSQ*DLTKLKASSL QVSHNDAQMLSEQCQLALTEFLKLNPQLNKQLYEERLAKELEIINSLHFASYFLVVSDLVQFAHNNDILIGPGRGSAVGS LVAFLLKITQIDPVANNLIFERFISRHRQGLPDIDIDIMETKRDLVIDYVMQKYGREQCAQIVTFQKFKTRSALRDVGKV FNHIEGAEDLLGKLPKDKSLLELDVNGVTDPVLQLSLKSFRLLWEVAREIINFPRQPSIHASGVVIVTEPLITTIPLMVG NNNNYVTQVSMDWLEWYNLNKFDLLGLINLTMIHEVVQAVKPKEVSVQQFLQQIPLDDEATFTNLTNQATLGVFQLESFG MKKVLKQIKPHNLHDLAIVLALYRPGPQDNINTFIANRNLGFDTSDIDPRILPILKETYGVLIFQEQVINIAKTVANYSL ETADSFRRAISKKNLQVIQDNMRSFYEGALANNFSLKAATTIFNYIQRFAGYGFNLSHALGYALLSY*TA*LKTHYFEQF NLW*LNHEQGKKEKQKQLLNEFISSGYEICPPLINKAKSDFSVQDKKLYLGFKLINGIGDKQAHALEHVQEVLKQNPNLS LIATVNLCLSKTVGGLELKDITLLQQAGCFNCFNYTVDFNLAKSFWVQSNHELFPKIPLDQPPVIN*KSFGF >Mature_872_residues MFVNLHTNSYYNFLNSTLSPQKLVDLAVQDQQVAVCLTDPNLFGATEFFLACQKAHIKPLIGLSVTVRHYEQNVNLLVIA QTNRGYQNLMCLALVKDQPDLQLEPFLDGNVVIICTQTELRLNTANPVYLAHGLSGRYPKIAVTQKPVKCQNTNKDLTLL LTLKQISQINSEHFQPLE*KLSRSLNEIQLDPPLLQQLRHQPFLSQKAAQQIFSEEELGNLQKLVEQSQ*DLTKLKASSL QVSHNDAQMLSEQCQLALTEFLKLNPQLNKQLYEERLAKELEIINSLHFASYFLVVSDLVQFAHNNDILIGPGRGSAVGS LVAFLLKITQIDPVANNLIFERFISRHRQGLPDIDIDIMETKRDLVIDYVMQKYGREQCAQIVTFQKFKTRSALRDVGKV FNHIEGAEDLLGKLPKDKSLLELDVNGVTDPVLQLSLKSFRLLWEVAREIINFPRQPSIHASGVVIVTEPLITTIPLMVG NNNNYVTQVSMDWLEWYNLNKFDLLGLINLTMIHEVVQAVKPKEVSVQQFLQQIPLDDEATFTNLTNQATLGVFQLESFG MKKVLKQIKPHNLHDLAIVLALYRPGPQDNINTFIANRNLGFDTSDIDPRILPILKETYGVLIFQEQVINIAKTVANYSL ETADSFRRAISKKNLQVIQDNMRSFYEGALANNFSLKAATTIFNYIQRFAGYGFNLSHALGYALLSY*TA*LKTHYFEQF NLW*LNHEQGKKEKQKQLLNEFISSGYEICPPLINKAKSDFSVQDKKLYLGFKLINGIGDKQAHALEHVQEVLKQNPNLS LIATVNLCLSKTVGGLELKDITLLQQAGCFNCFNYTVDFNLAKSFWVQSNHELFPKIPLDQPPVIN*KSFGF
Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase [H]
COG id: COG0587
COG function: function code L; DNA polymerase III, alpha subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DNA polymerase type-C family. DnaE subfamily [H]
Homologues:
Organism=Escherichia coli, GI1786381, Length=587, Percent_Identity=34.412265758092, Blast_Score=330, Evalue=2e-91,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011708 - InterPro: IPR004013 - InterPro: IPR003141 - InterPro: IPR004805 [H]
Pfam domain/function: PF07733 DNA_pol3_alpha; PF02811 PHP [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 98033; Mature: 98033
Theoretical pI: Translated: 7.19; Mature: 7.19
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFVNLHTNSYYNFLNSTLSPQKLVDLAVQDQQVAVCLTDPNLFGATEFFLACQKAHIKPL CEEEEECCHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEE IGLSVTVRHYEQNVNLLVIAQTNRGYQNLMCLALVKDQPDLQLEPFLDGNVVIICTQTEL CCCEEEEEEHHCCCCEEEEEECCCCHHHEEEEEEECCCCCCEECCCCCCCEEEEEECCEE RLNTANPVYLAHGLSGRYPKIAVTQKPVKCQNTNKDLTLLLTLKQISQINSEHFQPLEKL EECCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEHHHHHHHCHHHHHHHHHH SRSLNEIQLDPPLLQQLRHQPFLSQKAAQQIFSEEELGNLQKLVEQSQDLTKLKASSLQV HHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEE SHNDAQMLSEQCQLALTEFLKLNPQLNKQLYEERLAKELEIINSLHFASYFLVVSDLVQF CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AHNNDILIGPGRGSAVGSLVAFLLKITQIDPVANNLIFERFISRHRQGLPDIDIDIMETK HCCCCEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH RDLVIDYVMQKYGREQCAQIVTFQKFKTRSALRDVGKVFNHIEGAEDLLGKLPKDKSLLE HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEE LDVNGVTDPVLQLSLKSFRLLWEVAREIINFPRQPSIHASGVVIVTEPLITTIPLMVGNN EECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHCCEEECCC NNYVTQVSMDWLEWYNLNKFDLLGLINLTMIHEVVQAVKPKEVSVQQFLQQIPLDDEATF CCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHH TNLTNQATLGVFQLESFGMKKVLKQIKPHNLHDLAIVLALYRPGPQDNINTFIANRNLGF HCCCCCHHEEEHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCC DTSDIDPRILPILKETYGVLIFQEQVINIAKTVANYSLETADSFRRAISKKNLQVIQDNM CCCCCCCHHHHHHHHHHCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHH RSFYEGALANNFSLKAATTIFNYIQRFAGYGFNLSHALGYALLSYTALKTHYFEQFNLWL HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE NHEQGKKEKQKQLLNEFISSGYEICPPLINKAKSDFSVQDKKLYLGFKLINGIGDKQAHA CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEHHHHHHCCCCHHHHH LEHVQEVLKQNPNLSLIATVNLCLSKTVGGLELKDITLLQQAGCFNCFNYTVDFNLAKSF HHHHHHHHHCCCCEEEEEEHHHHHHHCCCCCEEHHHHHHHHCCCCEEEEEEEEEEHHHHH WVQSNHELFPKIPLDQPPVINKSFGF HCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MFVNLHTNSYYNFLNSTLSPQKLVDLAVQDQQVAVCLTDPNLFGATEFFLACQKAHIKPL CEEEEECCHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEE IGLSVTVRHYEQNVNLLVIAQTNRGYQNLMCLALVKDQPDLQLEPFLDGNVVIICTQTEL CCCEEEEEEHHCCCCEEEEEECCCCHHHEEEEEEECCCCCCEECCCCCCCEEEEEECCEE RLNTANPVYLAHGLSGRYPKIAVTQKPVKCQNTNKDLTLLLTLKQISQINSEHFQPLEKL EECCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEHHHHHHHCHHHHHHHHHH SRSLNEIQLDPPLLQQLRHQPFLSQKAAQQIFSEEELGNLQKLVEQSQDLTKLKASSLQV HHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEE SHNDAQMLSEQCQLALTEFLKLNPQLNKQLYEERLAKELEIINSLHFASYFLVVSDLVQF CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AHNNDILIGPGRGSAVGSLVAFLLKITQIDPVANNLIFERFISRHRQGLPDIDIDIMETK HCCCCEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH RDLVIDYVMQKYGREQCAQIVTFQKFKTRSALRDVGKVFNHIEGAEDLLGKLPKDKSLLE HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEE LDVNGVTDPVLQLSLKSFRLLWEVAREIINFPRQPSIHASGVVIVTEPLITTIPLMVGNN EECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHCCEEECCC NNYVTQVSMDWLEWYNLNKFDLLGLINLTMIHEVVQAVKPKEVSVQQFLQQIPLDDEATF CCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHH TNLTNQATLGVFQLESFGMKKVLKQIKPHNLHDLAIVLALYRPGPQDNINTFIANRNLGF HCCCCCHHEEEHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCC DTSDIDPRILPILKETYGVLIFQEQVINIAKTVANYSLETADSFRRAISKKNLQVIQDNM CCCCCCCHHHHHHHHHHCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHH RSFYEGALANNFSLKAATTIFNYIQRFAGYGFNLSHALGYALLSYTALKTHYFEQFNLWL HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE NHEQGKKEKQKQLLNEFISSGYEICPPLINKAKSDFSVQDKKLYLGFKLINGIGDKQAHA CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEHHHHHHCCCCHHHHH LEHVQEVLKQNPNLSLIATVNLCLSKTVGGLELKDITLLQQAGCFNCFNYTVDFNLAKSF HHHHHHHHHCCCCEEEEEEHHHHHHHCCCCCEEHHHHHHHHCCCCEEEEEEEEEEHHHHH WVQSNHELFPKIPLDQPPVINKSFGF HCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8948633 [H]