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The map label for this gene is ftsZ [H]

Identifier: 13508056

GI number: 13508056

Start: 376023

End: 377165

Strand: Direct

Name: ftsZ [H]

Synonym: MPN317

Alternate gene names: 13508056

Gene position: 376023-377165 (Clockwise)

Preceding gene: 13508055

Following gene: 13508057

Centisome position: 46.06

GC content: 38.5

Gene sequence:

>1143_bases
ATGGATTGAATACAAACAGCAGGTGCTGGTACTCAACTACCAGAGAACAACATTAAGATAGCCGTTTTTGGAATTGGTGG
TGCTGGTAACAACATTATTGATGACATGTTGCGCATGCACCCCGAATTGCAAACGGCTAACGTCCAGTTCTTTGCTTTAA
ACACTGATTTACAGCACTTAAAAACAAAGCGCTATGTCCAAAATAAGGCTGTGATTCAGTTTGAAGAATCCAAGGGCTTA
GGTGTTGGTGGTGATCCCCAAAAAGGTGCCGTTTTAGCACACCATTTTTTAGAGCAATTTCACAAACTTAGTGACAGCTT
TGATTTCTGTATTTTAGTCGCTGGTTTTGGTAAGGGGACTGGTACTGGTGCTACCCCGGTTTTTAGTAAATTTCTTAGCA
ACAAAGGGGTGTTAAATCTCTCGATTGTCAGTTACCCCGCAATGTGTGAAGGGTTAAAGGCACGCGAAAAAGCAGCTAAA
GGTTTAGAACGCTTAAACCAAGCGACTGACAGTTTTATGCTGTTCCGCAATGATCGCTGTACTGATGGCATTTACCAACT
AGCAAACGTTGCCATTGTCAAAACAATTAAAAACATTATTGAACTAATTAATCTACCACTACAGCAAAACATTGATTTTG
AAGACATTCGTTCTTTCTTTAAAAAACCAGCACAACGTTTAGAGAATGAAGCTAACTTGTTTCGCGTAACTAATACTTTT
ACTTTTAGCTTTGACGCGCACAATACAATTGAGCACTTTAGCCACAAATTGAAAAACTTTGAGTATGAAGGTTTTTTTGA
CCATAAGGTAGAAGGGGCGCAAAAGGTAATTTTAAAGGTGTTAGTCAACCAAGGTTTATATCCGCTTGATTTAACCCAAA
TTCAAGAGATTATTTGAGCCAAAATTGACAATCATAACCTAGAGGTACAACTTGGAGTTGACTTTACTGATGCCAACCCT
TCAGTGCAACTGTTTTTCTTAATGGAGAAAAAGCAAGCAGTGTCCTCTGACTTTATTCAAAAACCAGCATTTATCTCAGT
TAAAGAAGTAAATCAGAAACCGGCCAAACCGTTCCAAGTTTTGAATGATTTAAAGGAGCTGGGACTGAAATACGTCAAAC
AGCAAACCGGATTTAATTATTAG

Upstream 100 bases:

>100_bases
ACTCAGACAAAATTGAAAAGCAGTTTAAAAAGTCGTTTTTAATGTTGAAGGTACACACGCACATTAATAAGTTAGTGCAA
AAACTAATAAAGTAAGCTTT

Downstream 100 bases:

>100_bases
TGGTCTTTCTTCTTTAGAATAAGCTAACTAATAAGAAGGTTAATGGCTGTTGCAAGTAAGAAGTTCACTGAACGTCAATT
TTTATTTTTTGTTGTCAACT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDWIQTAGAGTQLPENNIKIAVFGIGGAGNNIIDDMLRMHPELQTANVQFFALNTDLQHLKTKRYVQNKAVIQFEESKGL
GVGGDPQKGAVLAHHFLEQFHKLSDSFDFCILVAGFGKGTGTGATPVFSKFLSNKGVLNLSIVSYPAMCEGLKAREKAAK
GLERLNQATDSFMLFRNDRCTDGIYQLANVAIVKTIKNIIELINLPLQQNIDFEDIRSFFKKPAQRLENEANLFRVTNTF
TFSFDAHNTIEHFSHKLKNFEYEGFFDHKVEGAQKVILKVLVNQGLYPLDLTQIQEIIWAKIDNHNLEVQLGVDFTDANP
SVQLFFLMEKKQAVSSDFIQKPAFISVKEVNQKPAKPFQVLNDLKELGLKYVKQQTGFNY

Sequences:

>Translated_380_residues
MD*IQTAGAGTQLPENNIKIAVFGIGGAGNNIIDDMLRMHPELQTANVQFFALNTDLQHLKTKRYVQNKAVIQFEESKGL
GVGGDPQKGAVLAHHFLEQFHKLSDSFDFCILVAGFGKGTGTGATPVFSKFLSNKGVLNLSIVSYPAMCEGLKAREKAAK
GLERLNQATDSFMLFRNDRCTDGIYQLANVAIVKTIKNIIELINLPLQQNIDFEDIRSFFKKPAQRLENEANLFRVTNTF
TFSFDAHNTIEHFSHKLKNFEYEGFFDHKVEGAQKVILKVLVNQGLYPLDLTQIQEII*AKIDNHNLEVQLGVDFTDANP
SVQLFFLMEKKQAVSSDFIQKPAFISVKEVNQKPAKPFQVLNDLKELGLKYVKQQTGFNY
>Mature_380_residues
MD*IQTAGAGTQLPENNIKIAVFGIGGAGNNIIDDMLRMHPELQTANVQFFALNTDLQHLKTKRYVQNKAVIQFEESKGL
GVGGDPQKGAVLAHHFLEQFHKLSDSFDFCILVAGFGKGTGTGATPVFSKFLSNKGVLNLSIVSYPAMCEGLKAREKAAK
GLERLNQATDSFMLFRNDRCTDGIYQLANVAIVKTIKNIIELINLPLQQNIDFEDIRSFFKKPAQRLENEANLFRVTNTF
TFSFDAHNTIEHFSHKLKNFEYEGFFDHKVEGAQKVILKVLVNQGLYPLDLTQIQEII*AKIDNHNLEVQLGVDFTDANP
SVQLFFLMEKKQAVSSDFIQKPAFISVKEVNQKPAKPFQVLNDLKELGLKYVKQQTGFNY

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=201, Percent_Identity=32.3383084577114, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 42389; Mature: 42389

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQTAGAGTQLPENNIKIAVFGIGGAGNNIIDDMLRMHPELQTANVQFFALNTDLQHLK
CCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCEECCEEEEEECCCHHHHH
TKRYVQNKAVIQFEESKGLGVGGDPQKGAVLAHHFLEQFHKLSDSFDFCILVAGFGKGTG
HHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
TGATPVFSKFLSNKGVLNLSIVSYPAMCEGLKAREKAAKGLERLNQATDSFMLFRNDRCT
CCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
DGIYQLANVAIVKTIKNIIELINLPLQQNIDFEDIRSFFKKPAQRLENEANLFRVTNTFT
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
FSFDAHNTIEHFSHKLKNFEYEGFFDHKVEGAQKVILKVLVNQGLYPLDLTQIQEIIAKI
EEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
DNHNLEVQLGVDFTDANPSVQLFFLMEKKQAVSSDFIQKPAFISVKEVNQKPAKPFQVLN
CCCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHCCCCEEEHHHHCCCCCCHHHHHH
DLKELGLKYVKQQTGFNY
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDIQTAGAGTQLPENNIKIAVFGIGGAGNNIIDDMLRMHPELQTANVQFFALNTDLQHLK
CCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCEECCEEEEEECCCHHHHH
TKRYVQNKAVIQFEESKGLGVGGDPQKGAVLAHHFLEQFHKLSDSFDFCILVAGFGKGTG
HHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
TGATPVFSKFLSNKGVLNLSIVSYPAMCEGLKAREKAAKGLERLNQATDSFMLFRNDRCT
CCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
DGIYQLANVAIVKTIKNIIELINLPLQQNIDFEDIRSFFKKPAQRLENEANLFRVTNTFT
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
FSFDAHNTIEHFSHKLKNFEYEGFFDHKVEGAQKVILKVLVNQGLYPLDLTQIQEIIAKI
EEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
DNHNLEVQLGVDFTDANPSVQLFFLMEKKQAVSSDFIQKPAFISVKEVNQKPAKPFQVLN
CCCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHCCCCEEEHHHHCCCCCCHHHHHH
DLKELGLKYVKQQTGFNY
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]