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The map label for this gene is arcC [C]

Identifier: 13508046

GI number: 13508046

Start: 361468

End: 362397

Strand: Direct

Name: arcC [C]

Synonym: MPN307

Alternate gene names: 13508046

Gene position: 361468-362397 (Clockwise)

Preceding gene: 13508045

Following gene: 13508047

Centisome position: 44.28

GC content: 44.73

Gene sequence:

>930_bases
ATGCAAAAAATTGTCATAGCATTGGGTGGTAATGCATTAGGTAACAATCCCACCGAACAAAAGGACTTGGTACAACTACC
AGCACGACAGGCGGTTGCTTTATTAAAGCAGGGTTATCAGATATTATTGGGTCATGGTAACGGTCCACAGGTTGGCATGA
TCTACAACGCCTTTAGTGCGGCCAAACAAGTCAACCCTAATACACCCACTGTACCATTTGCTGAAAGTGGGGCAATGTCT
CAGGGTTACATTGGACTGCATTTGTTAACAGCATTGTACAATGAGCTGCTACACCAAAAACTACCCCATCAAGCCGTGTA
CTTTTTAACACAAACCTTAGTAGAAGCGAGCGATCCTGCTTTTCAAAACCCAAATAAACCAGTTGGTCCGTTTTACAACA
CAGAGGAAACAGCACGCTCAGCTAATCCAAACAGCACCGTGGTGGAAGATGCAGGGCGGGGTTGGCGTAAAGTAGTAGCG
TCCCCCAAACCAGTTGATGTTTTGGGAATTGATGCCATTAAAAGTAGCTTTAACCAAGGCAACTTGGTGATTGTTGGTGG
CGGTGGCGGTGTACCCACAATTAAGACCAAAAGTGGTTATGCAACGGTTGATGGGGTGATTGATAAGGATCTAGCATTGA
GTGAAATTGCCATTAAGGTAGAGGCTGACCTGTTTGTTATTCTCACTGCCGTGGACTTTGTCTACATTAACTATGGTCAA
CCAAACGAGCAAAAGCTAACCTGCATTAACACCAAGGAAGCTAAGACCTTAATGGCCGCAAACCAGTTTGCTAAAGGTAG
TATGCTCCCTAAGGTAGAAGCGTGTTTAAACTTTGTCCAGTCGGGTACCAATAAGACGGCCATTATTGCCCAATTAGACC
AATTAGCTGCGGCCATTGCGGGCAAGATTGGTACTAAAATTGTCAAGTAG

Upstream 100 bases:

>100_bases
ATACGGTGTTTCAGTCCAAGCATAACATGGCCTTTATCCAAGCAGAAAACCGCTTGCACACGATTAAGGCCGTTATTTTA
GCTACTTTAGGGTATTAAAG

Downstream 100 bases:

>100_bases
TTATGAAACAACAAAAACCCAAAATTAGCTTTATAGCAGCGATGCTAATTGTTATCGGCTCGTCCATAGGTGCTGGTATC
TTTTTTAAATCCAGCACTGT

Product: carbamate kinase

Products: ADP; carbamoyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MQKIVIALGGNALGNNPTEQKDLVQLPARQAVALLKQGYQILLGHGNGPQVGMIYNAFSAAKQVNPNTPTVPFAESGAMS
QGYIGLHLLTALYNELLHQKLPHQAVYFLTQTLVEASDPAFQNPNKPVGPFYNTEETARSANPNSTVVEDAGRGWRKVVA
SPKPVDVLGIDAIKSSFNQGNLVIVGGGGGVPTIKTKSGYATVDGVIDKDLALSEIAIKVEADLFVILTAVDFVYINYGQ
PNEQKLTCINTKEAKTLMAANQFAKGSMLPKVEACLNFVQSGTNKTAIIAQLDQLAAAIAGKIGTKIVK

Sequences:

>Translated_309_residues
MQKIVIALGGNALGNNPTEQKDLVQLPARQAVALLKQGYQILLGHGNGPQVGMIYNAFSAAKQVNPNTPTVPFAESGAMS
QGYIGLHLLTALYNELLHQKLPHQAVYFLTQTLVEASDPAFQNPNKPVGPFYNTEETARSANPNSTVVEDAGRGWRKVVA
SPKPVDVLGIDAIKSSFNQGNLVIVGGGGGVPTIKTKSGYATVDGVIDKDLALSEIAIKVEADLFVILTAVDFVYINYGQ
PNEQKLTCINTKEAKTLMAANQFAKGSMLPKVEACLNFVQSGTNKTAIIAQLDQLAAAIAGKIGTKIVK
>Mature_309_residues
MQKIVIALGGNALGNNPTEQKDLVQLPARQAVALLKQGYQILLGHGNGPQVGMIYNAFSAAKQVNPNTPTVPFAESGAMS
QGYIGLHLLTALYNELLHQKLPHQAVYFLTQTLVEASDPAFQNPNKPVGPFYNTEETARSANPNSTVVEDAGRGWRKVVA
SPKPVDVLGIDAIKSSFNQGNLVIVGGGGGVPTIKTKSGYATVDGVIDKDLALSEIAIKVEADLFVILTAVDFVYINYGQ
PNEQKLTCINTKEAKTLMAANQFAKGSMLPKVEACLNFVQSGTNKTAIIAQLDQLAAAIAGKIGTKIVK

Specific function: Unknown

COG id: COG0549

COG function: function code E; Carbamate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbamate kinase family

Homologues:

Organism=Escherichia coli, GI1789238, Length=308, Percent_Identity=43.5064935064935, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI1786516, Length=314, Percent_Identity=39.8089171974522, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1786732, Length=311, Percent_Identity=37.2990353697749, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARCL_MYCPN (P78030)

Other databases:

- EMBL:   U00089
- EMBL:   U59896
- PIR:   S73855
- RefSeq:   NP_109995.1
- ProteinModelPortal:   P78030
- SMR:   P78030
- IntAct:   P78030
- GeneID:   876908
- GenomeReviews:   U00089_GR
- KEGG:   mpn:MPN307
- HOGENOM:   HBG296625
- OMA:   VVPFPEC
- ProtClustDB:   PRK12353
- BioCyc:   MPNE272634:MPN307-MONOMER
- InterPro:   IPR001048
- InterPro:   IPR003964
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000723
- PRINTS:   PR01469

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: 2.7.2.2

Molecular weight: Translated: 32785; Mature: 32785

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIVIALGGNALGNNPTEQKDLVQLPARQAVALLKQGYQILLGHGNGPQVGMIYNAFSA
CCEEEEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCEEEEECCCCCEEEEEEHHHHH
AKQVNPNTPTVPFAESGAMSQGYIGLHLLTALYNELLHQKLPHQAVYFLTQTLVEASDPA
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
FQNPNKPVGPFYNTEETARSANPNSTVVEDAGRGWRKVVASPKPVDVLGIDAIKSSFNQG
CCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCCCHHHHHCCCCCCEEEEHHHHHHCCCCC
NLVIVGGGGGVPTIKTKSGYATVDGVIDKDLALSEIAIKVEADLFVILTAVDFVYINYGQ
CEEEEECCCCCCEEEECCCCEEECCCCCCCCCHHHEEEEECCCEEEEEEEEEEEEEECCC
PNEQKLTCINTKEAKTLMAANQFAKGSMLPKVEACLNFVQSGTNKTAIIAQLDQLAAAIA
CCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GKIGTKIVK
HHHHHHCCC
>Mature Secondary Structure
MQKIVIALGGNALGNNPTEQKDLVQLPARQAVALLKQGYQILLGHGNGPQVGMIYNAFSA
CCEEEEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCEEEEECCCCCEEEEEEHHHHH
AKQVNPNTPTVPFAESGAMSQGYIGLHLLTALYNELLHQKLPHQAVYFLTQTLVEASDPA
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
FQNPNKPVGPFYNTEETARSANPNSTVVEDAGRGWRKVVASPKPVDVLGIDAIKSSFNQG
CCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCCCHHHHHCCCCCCEEEEHHHHHHCCCCC
NLVIVGGGGGVPTIKTKSGYATVDGVIDKDLALSEIAIKVEADLFVILTAVDFVYINYGQ
CEEEEECCCCCCEEEECCCCEEECCCCCCCCCHHHEEEEECCCEEEEEEEEEEEEEECCC
PNEQKLTCINTKEAKTLMAANQFAKGSMLPKVEACLNFVQSGTNKTAIIAQLDQLAAAIA
CCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GKIGTKIVK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; NH3; CO2

Specific reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633; 9098066