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The map label for this gene is plsB [H]

Identifier: 13508038

GI number: 13508038

Start: 352734

End: 353534

Strand: Direct

Name: plsB [H]

Synonym: MPN299

Alternate gene names: 13508038

Gene position: 352734-353534 (Clockwise)

Preceding gene: 13508037

Following gene: 13508039

Centisome position: 43.21

GC content: 40.7

Gene sequence:

>801_bases
ATGAAAAAATTAACACAAGCTTTTTTGCGTTTTTGTCTGAGATTCTTACAACTGCTCAGTTTAGTTTTGGTTTTACCCGT
TTTTGTGTTAATGCTCATCTCTAGCCTAATTAGTGCTAAAAATTATGAAAGCATCCCGGAAAACTATCCCCCAGAAATCC
GCTTTAAGAAGGTGTACCGCTTGGTATCACTTTTCCTCTACATTAAAGGAGTTAAAGTGGTTATTGTTAACCCTGAAAAT
GTGCCTAAAAAGGCTGTTTTAGTGGTAGCTAATCATAAGTCCAATTTAGATCCCCTCATCCTCATTAAGGCCTTTGGTAA
AACTGAAGGGGTACCACCGTTAACCTTTATTGCCAAGATTGAACTGCAAGATACCTGACTGTTCAAGATTATGAAGCTGA
TTGACTGTGTCTTTATTGATCGAAAAAACCTGCGTCAAATGGCAGCATCCTTGGAACAACAGCAGCAAATTATCCGCCAG
GGCACTGCTCTGTGTGTTTTTCCTGAGGGTACACGGGTACTCTCTAGGCAAATTGGTGAGTTTAAATCGGGCGCTTTAAA
GGTCGCTTACAACGCCTTTGTGCCGATTGTGCCACTAACGATTGTGGGTAGCATGGGACACATGGAGTCCAAAAAGCGTT
TACAAAAAGCCCAGGTAGAGCGCGATCGTGGTTATAAAATCCAGGTCATCTTTAACACACCTATTAACCCAATTAACTTT
AACCAGATTGATTCGCAAAATGTGGCTAATAATGTCTGGCGTGAAATTAGTCAAACTTATGCGCAATATTGCCAAGACTA
G

Upstream 100 bases:

>100_bases
AACGTTATAACTGCCAGATTGACCCTAAGATTGAACTTTTGCTCTCGGTTAGTTACAGCAGTAATAACATTACTGCCATC
TGTTTGGCACAACAAACACC

Downstream 100 bases:

>100_bases
ATGATCACGTTAATCTGGTGCCAAGATAAACACTTCGGGATTGGGAGAGACAACACCATTCCCTGAAAGTTAACGGAAGC
CAACCAACACTTCTATAACA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKKLTQAFLRFCLRFLQLLSLVLVLPVFVLMLISSLISAKNYESIPENYPPEIRFKKVYRLVSLFLYIKGVKVVIVNPEN
VPKKAVLVVANHKSNLDPLILIKAFGKTEGVPPLTFIAKIELQDTWLFKIMKLIDCVFIDRKNLRQMAASLEQQQQIIRQ
GTALCVFPEGTRVLSRQIGEFKSGALKVAYNAFVPIVPLTIVGSMGHMESKKRLQKAQVERDRGYKIQVIFNTPINPINF
NQIDSQNVANNVWREISQTYAQYCQD

Sequences:

>Translated_266_residues
MKKLTQAFLRFCLRFLQLLSLVLVLPVFVLMLISSLISAKNYESIPENYPPEIRFKKVYRLVSLFLYIKGVKVVIVNPEN
VPKKAVLVVANHKSNLDPLILIKAFGKTEGVPPLTFIAKIELQDT*LFKIMKLIDCVFIDRKNLRQMAASLEQQQQIIRQ
GTALCVFPEGTRVLSRQIGEFKSGALKVAYNAFVPIVPLTIVGSMGHMESKKRLQKAQVERDRGYKIQVIFNTPINPINF
NQIDSQNVANNVWREISQTYAQYCQD
>Mature_266_residues
MKKLTQAFLRFCLRFLQLLSLVLVLPVFVLMLISSLISAKNYESIPENYPPEIRFKKVYRLVSLFLYIKGVKVVIVNPEN
VPKKAVLVVANHKSNLDPLILIKAFGKTEGVPPLTFIAKIELQDT*LFKIMKLIDCVFIDRKNLRQMAASLEQQQQIIRQ
GTALCVFPEGTRVLSRQIGEFKSGALKVAYNAFVPIVPLTIVGSMGHMESKKRLQKAQVERDRGYKIQVIFNTPINPINF
NQIDSQNVANNVWREISQTYAQYCQD

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320151, Length=147, Percent_Identity=32.6530612244898, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 30210; Mature: 30210

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTQAFLRFCLRFLQLLSLVLVLPVFVLMLISSLISAKNYESIPENYPPEIRFKKVYR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LVSLFLYIKGVKVVIVNPENVPKKAVLVVANHKSNLDPLILIKAFGKTEGVPPLTFIAKI
HHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHEEH
ELQDTLFKIMKLIDCVFIDRKNLRQMAASLEQQQQIIRQGTALCVFPEGTRVLSRQIGEF
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
KSGALKVAYNAFVPIVPLTIVGSMGHMESKKRLQKAQVERDRGYKIQVIFNTPINPINFN
HCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
QIDSQNVANNVWREISQTYAQYCQD
CCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLTQAFLRFCLRFLQLLSLVLVLPVFVLMLISSLISAKNYESIPENYPPEIRFKKVYR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LVSLFLYIKGVKVVIVNPENVPKKAVLVVANHKSNLDPLILIKAFGKTEGVPPLTFIAKI
HHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHEEH
ELQDTLFKIMKLIDCVFIDRKNLRQMAASLEQQQQIIRQGTALCVFPEGTRVLSRQIGEF
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
KSGALKVAYNAFVPIVPLTIVGSMGHMESKKRLQKAQVERDRGYKIQVIFNTPINPINFN
HCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
QIDSQNVANNVWREISQTYAQYCQD
CCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]