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The map label for this gene is cpt2

Identifier: 13507853

GI number: 13507853

Start: 148751

End: 150553

Strand: Direct

Name: cpt2

Synonym: MPN114

Alternate gene names: NA

Gene position: 148751-150553 (Clockwise)

Preceding gene: 13507852

Following gene: 13507854

Centisome position: 18.22

GC content: 43.54

Gene sequence:

>1803_bases
ATGGACACTAAATTAACACCACCCTGGTTGCGTCAAGAAAATAACCTGCTCAACCCCGAAGTTACCCAACGTTTGTTTAT
CAACCAGGACAACATTCCGAACTTACCCACTGAAGCCCCCCAAGTTTATTTAGCCCGTTTTTTGGAATGAGTTGAACCAC
TAGTCTCGAAAGTAAAATTTGTGAAAGCACAAGCAGCAGTTCAGGATTACCTCAATTCTAAAGCCTGTGCACAAATTGAA
ACCATTATTGCAGAACGGGCGCAAAACACCCATTCGAGTTGGTTAGCTAACTGGTGGGTGCAGTACGCTTATTTAACTTC
GACTGGCCCGGTTAGTCCGGAAGTTAATGCACCCTATTATTTAGAGCTCCCGACTGTTGGTTGAAGTCAAGCCGAGTTAG
CAGCAGCATTGTCAGCCCAGCTATGACACATATACCAGCAAGTCCAAAAACGGCAGTTAACGAGCTTTAGTGTCAAGGAC
AAGCTGTTTTCACTCGATACCTTGCAATCAATCTTTGCTAGTTGCCAGATTCACCGCGCTGATGGGGATGTGTACTTTGT
TAATGATCAACCTGCTAACTTTATTGTGGTGATTAAGAACAATGTCTTCTATAAGTTAGTAATAGATAACAGTGGTAGCT
TAGAACAACTGCAAGCGCAACTGCAGTTAAGCTTTGTGCAAATCTTAGACAATGAGCTAAGTCACCCACCGCACTGGAAC
TTACTCACTGCTACCACAACCAAAGCGGAGTCACAAAGTTTACTCGATCAGTTGTGAGCGCAAAACCCAGAAATGTTGTT
GGACATCTATAACAGTGCCTTTATTGTGAACTTGGACAACGTCGAATTAACGACTCCCTTACAACTGTTGCGCAATTCGA
CATGAACCCCTAACTTTAACCGTTGGCACGCTAAGGGGATTCAGTTGGTCATTACTAAGAACGCTCAGTTAGTCATTCTA
GCGGATCACACTAGTTTTGACGGTTCTAGTGTAGCTACCCTAGCCAACATCTTTGTCTCTAAACTCCAAAAGGTCAACAC
TGAGGGTGCCAGCGCTTTAACACCGACCATGCTTTCCTTTCCAACAGTAGACCAGGATAAGCAAAAGTATTTTAAGCAAT
TGAGCAAAAATTTTAAGGACTATGTGTACAATGCCGTTATGTTTGAACTGAAATGGGACTGGTTTACGAAGCCACTTATC
AAAGCCAAAGGGATTAAGAACTCCGAAGCCTTTATCCATCTCTGTTACCAAATTGCCCAGTACCAAACGAACAAAAAGTT
GCAGAACACCTATGTGGCCGTGGACATGCGTCAGTACTTCCGGGGACGCACCGAGTGTCTTCGTCCTTTAAGTAAACAAT
CAGTTGCCTTTGTCAAACGCTACTGCAAAGATCCGAAAGGTACCTTAAAGCAGTTCCGAAAGTACTACCCAGCGATTGAA
AGTCTCCACTTTGAAAAAACCCGGTTAGCGCAAAAGGGTAGTGGGGTCAACCGTCACTTGCTGGGAGCATATTTGGCTTG
GAATGAACACCAAGACACAATAGCTAAACCCGCTTTATTTGAAACAAAGGCTTGAAAAACGATTGCTGCCAACCCACTGT
CCACATCGAGCATTGTGGACAAGTATTTGCGCAACTTTTCCTTCGACCCCGTAGAGCCAAACGGCATTGGTATTGCCTAT
GCCATTGATGACACTAATTTCCGTGCCATTCTCAGTGTGTATCAGCACAACTTACAGTACCTCAAAGATTGGATGAAACA
CTTTGAACAAACAGTGAAAACAATCCTTAAAACTCTTAAATAA

Upstream 100 bases:

>100_bases
GCACTACTAGTGACTTACATGATAGTGCGCAAAGTGAAGTATGGCAAAGTGTGAGTTAACCCTAAATTTAAAAAAGTCTT
TGCACTAGGAGAACAACAAT

Downstream 100 bases:

>100_bases
AATTACTCCTTAATGGTTAATTGAGTTAAAACGGTTGGAGATTGTTAAAATATTGGCGCTATACAAAGTAGTCTTTACGA
CTCGCCCGAATGCCGTTGAT

Product: acyltransferase

Products: CoA; O-acetylcarnitine

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MDTKLTPPWLRQENNLLNPEVTQRLFINQDNIPNLPTEAPQVYLARFLEWVEPLVSKVKFVKAQAAVQDYLNSKACAQIE
TIIAERAQNTHSSWLANWWVQYAYLTSTGPVSPEVNAPYYLELPTVGWSQAELAAALSAQLWHIYQQVQKRQLTSFSVKD
KLFSLDTLQSIFASCQIHRADGDVYFVNDQPANFIVVIKNNVFYKLVIDNSGSLEQLQAQLQLSFVQILDNELSHPPHWN
LLTATTTKAESQSLLDQLWAQNPEMLLDIYNSAFIVNLDNVELTTPLQLLRNSTWTPNFNRWHAKGIQLVITKNAQLVIL
ADHTSFDGSSVATLANIFVSKLQKVNTEGASALTPTMLSFPTVDQDKQKYFKQLSKNFKDYVYNAVMFELKWDWFTKPLI
KAKGIKNSEAFIHLCYQIAQYQTNKKLQNTYVAVDMRQYFRGRTECLRPLSKQSVAFVKRYCKDPKGTLKQFRKYYPAIE
SLHFEKTRLAQKGSGVNRHLLGAYLAWNEHQDTIAKPALFETKAWKTIAANPLSTSSIVDKYLRNFSFDPVEPNGIGIAY
AIDDTNFRAILSVYQHNLQYLKDWMKHFEQTVKTILKTLK

Sequences:

>Translated_600_residues
MDTKLTPPWLRQENNLLNPEVTQRLFINQDNIPNLPTEAPQVYLARFLE*VEPLVSKVKFVKAQAAVQDYLNSKACAQIE
TIIAERAQNTHSSWLANWWVQYAYLTSTGPVSPEVNAPYYLELPTVG*SQAELAAALSAQL*HIYQQVQKRQLTSFSVKD
KLFSLDTLQSIFASCQIHRADGDVYFVNDQPANFIVVIKNNVFYKLVIDNSGSLEQLQAQLQLSFVQILDNELSHPPHWN
LLTATTTKAESQSLLDQL*AQNPEMLLDIYNSAFIVNLDNVELTTPLQLLRNST*TPNFNRWHAKGIQLVITKNAQLVIL
ADHTSFDGSSVATLANIFVSKLQKVNTEGASALTPTMLSFPTVDQDKQKYFKQLSKNFKDYVYNAVMFELKWDWFTKPLI
KAKGIKNSEAFIHLCYQIAQYQTNKKLQNTYVAVDMRQYFRGRTECLRPLSKQSVAFVKRYCKDPKGTLKQFRKYYPAIE
SLHFEKTRLAQKGSGVNRHLLGAYLAWNEHQDTIAKPALFETKA*KTIAANPLSTSSIVDKYLRNFSFDPVEPNGIGIAY
AIDDTNFRAILSVYQHNLQYLKDWMKHFEQTVKTILKTLK
>Mature_600_residues
MDTKLTPPWLRQENNLLNPEVTQRLFINQDNIPNLPTEAPQVYLARFLE*VEPLVSKVKFVKAQAAVQDYLNSKACAQIE
TIIAERAQNTHSSWLANWWVQYAYLTSTGPVSPEVNAPYYLELPTVG*SQAELAAALSAQL*HIYQQVQKRQLTSFSVKD
KLFSLDTLQSIFASCQIHRADGDVYFVNDQPANFIVVIKNNVFYKLVIDNSGSLEQLQAQLQLSFVQILDNELSHPPHWN
LLTATTTKAESQSLLDQL*AQNPEMLLDIYNSAFIVNLDNVELTTPLQLLRNST*TPNFNRWHAKGIQLVITKNAQLVIL
ADHTSFDGSSVATLANIFVSKLQKVNTEGASALTPTMLSFPTVDQDKQKYFKQLSKNFKDYVYNAVMFELKWDWFTKPLI
KAKGIKNSEAFIHLCYQIAQYQTNKKLQNTYVAVDMRQYFRGRTECLRPLSKQSVAFVKRYCKDPKGTLKQFRKYYPAIE
SLHFEKTRLAQKGSGVNRHLLGAYLAWNEHQDTIAKPALFETKA*KTIAANPLSTSSIVDKYLRNFSFDPVEPNGIGIAY
AIDDTNFRAILSVYQHNLQYLKDWMKHFEQTVKTILKTLK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carnitine/choline acetyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI21618331, Length=580, Percent_Identity=23.6206896551724, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI73623028, Length=580, Percent_Identity=24.8275862068966, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI73623030, Length=580, Percent_Identity=24.8275862068966, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI23238256, Length=584, Percent_Identity=24.486301369863, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4758050, Length=584, Percent_Identity=24.486301369863, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI223468678, Length=584, Percent_Identity=24.486301369863, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI223468672, Length=584, Percent_Identity=24.486301369863, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI23238254, Length=584, Percent_Identity=24.486301369863, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI31542325, Length=603, Percent_Identity=23.0514096185738, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI218931226, Length=571, Percent_Identity=23.8178633975482, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI218931221, Length=571, Percent_Identity=23.8178633975482, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI188595684, Length=571, Percent_Identity=23.8178633975482, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI188595672, Length=571, Percent_Identity=23.8178633975482, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI188595668, Length=571, Percent_Identity=23.8178633975482, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI218931224, Length=572, Percent_Identity=23.7762237762238, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI188595670, Length=572, Percent_Identity=23.7762237762238, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI223468670, Length=517, Percent_Identity=25.3384912959381, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI221316602, Length=631, Percent_Identity=22.0285261489699, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4503023, Length=631, Percent_Identity=23.4548335974643, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI223468674, Length=294, Percent_Identity=27.2108843537415, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17549962, Length=570, Percent_Identity=23.859649122807, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71998231, Length=527, Percent_Identity=25.426944971537, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17564458, Length=510, Percent_Identity=21.1764705882353, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115532914, Length=432, Percent_Identity=25.2314814814815, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115532916, Length=432, Percent_Identity=25.2314814814815, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562514, Length=520, Percent_Identity=22.6923076923077, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI25155169, Length=448, Percent_Identity=22.3214285714286, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323599, Length=573, Percent_Identity=23.2111692844677, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6319337, Length=618, Percent_Identity=24.4336569579288, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI45550701, Length=574, Percent_Identity=25.0871080139373, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI116007970, Length=557, Percent_Identity=25.3141831238779, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24647634, Length=553, Percent_Identity=24.0506329113924, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24584005, Length=581, Percent_Identity=23.9242685025818, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24656312, Length=610, Percent_Identity=25.4098360655738, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24650707, Length=577, Percent_Identity=23.5701906412478, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357723, Length=577, Percent_Identity=23.5701906412478, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24650705, Length=577, Percent_Identity=23.5701906412478, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24650712, Length=577, Percent_Identity=23.5701906412478, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24650710, Length=577, Percent_Identity=23.5701906412478, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281363114, Length=586, Percent_Identity=23.5494880546075, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281363112, Length=586, Percent_Identity=23.5494880546075, Blast_Score=99, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000542 [H]

Pfam domain/function: PF00755 Carn_acyltransf [H]

EC number: 2.3.1.7

Molecular weight: Translated: 67662; Mature: 67662

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00440 ACYLTRANSF_C_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKLTPPWLRQENNLLNPEVTQRLFINQDNIPNLPTEAPQVYLARFLEVEPLVSKVKFV
CCCCCCCHHHCCCCCCCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KAQAAVQDYLNSKACAQIETIIAERAQNTHSSWLANWWVQYAYLTSTGPVSPEVNAPYYL
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEE
ELPTVGSQAELAAALSAQLHIYQQVQKRQLTSFSVKDKLFSLDTLQSIFASCQIHRADGD
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCC
VYFVNDQPANFIVVIKNNVFYKLVIDNSGSLEQLQAQLQLSFVQILDNELSHPPHWNLLT
EEEECCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
ATTTKAESQSLLDQLAQNPEMLLDIYNSAFIVNLDNVELTTPLQLLRNSTTPNFNRWHAK
EECCCHHHHHHHHHHHCCHHHHHHHHCCEEEEEECCCEECCHHHHHHCCCCCCCCCEECC
GIQLVITKNAQLVILADHTSFDGSSVATLANIFVSKLQKVNTEGASALTPTMLSFPTVDQ
CEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCH
DKQKYFKQLSKNFKDYVYNAVMFELKWDWFTKPLIKAKGIKNSEAFIHLCYQIAQYQTNK
HHHHHHHHHHHHHHHHHHHHHEEEEECCHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHCC
KLQNTYVAVDMRQYFRGRTECLRPLSKQSVAFVKRYCKDPKGTLKQFRKYYPAIESLHFE
HHHHHEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHH
KTRLAQKGSGVNRHLLGAYLAWNEHQDTIAKPALFETKAKTIAANPLSTSSIVDKYLRNF
HHHHHHCCCCCCHHHHHHHHCCCCCCHHHCCCHHHHHHCHHEECCCCCHHHHHHHHHHCC
SFDPVEPNGIGIAYAIDDTNFRAILSVYQHNLQYLKDWMKHFEQTVKTILKTLK
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTKLTPPWLRQENNLLNPEVTQRLFINQDNIPNLPTEAPQVYLARFLEVEPLVSKVKFV
CCCCCCCHHHCCCCCCCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KAQAAVQDYLNSKACAQIETIIAERAQNTHSSWLANWWVQYAYLTSTGPVSPEVNAPYYL
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEE
ELPTVGSQAELAAALSAQLHIYQQVQKRQLTSFSVKDKLFSLDTLQSIFASCQIHRADGD
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCC
VYFVNDQPANFIVVIKNNVFYKLVIDNSGSLEQLQAQLQLSFVQILDNELSHPPHWNLLT
EEEECCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
ATTTKAESQSLLDQLAQNPEMLLDIYNSAFIVNLDNVELTTPLQLLRNSTTPNFNRWHAK
EECCCHHHHHHHHHHHCCHHHHHHHHCCEEEEEECCCEECCHHHHHHCCCCCCCCCEECC
GIQLVITKNAQLVILADHTSFDGSSVATLANIFVSKLQKVNTEGASALTPTMLSFPTVDQ
CEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCH
DKQKYFKQLSKNFKDYVYNAVMFELKWDWFTKPLIKAKGIKNSEAFIHLCYQIAQYQTNK
HHHHHHHHHHHHHHHHHHHHHEEEEECCHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHCC
KLQNTYVAVDMRQYFRGRTECLRPLSKQSVAFVKRYCKDPKGTLKQFRKYYPAIESLHFE
HHHHHEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHH
KTRLAQKGSGVNRHLLGAYLAWNEHQDTIAKPALFETKAKTIAANPLSTSSIVDKYLRNF
HHHHHHCCCCCCHHHHHHHHCCCCCCHHHCCCHHHHHHCHHEECCCCCHHHHHHHHHHCC
SFDPVEPNGIGIAYAIDDTNFRAILSVYQHNLQYLKDWMKHFEQTVKTILKTLK
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acetyl-CoA; carnitine

Specific reaction: acetyl-CoA + carnitine = CoA + O-acetylcarnitine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]