Click here to switch to the map view.

The map label for this gene is efp

Identifier: 13507768

GI number: 13507768

Start: 33979

End: 34551

Strand: Direct

Name: efp

Synonym: MPN029

Alternate gene names: 13507768

Gene position: 33979-34551 (Clockwise)

Preceding gene: 13507767

Following gene: 13507769

Centisome position: 4.16

GC content: 41.54

Gene sequence:

>573_bases
ATGGCAGACATGATTGAAGCGAAAAGTTTACGCAGTGGACAAACGATTTTTGGTCCCAATAAAGAGATTCTGTTGGTGTT
AGAAAACACCTTTAATAAGACCGCAATGCGCCAGGGAATTGTTAAAACCAAGGTCAAAAACTTACGCACTGGGGCCATTG
TTTGGATTGAGTTTACCGGAGACAAGTTAGAACAAGTCATTATTGACAAGAAGAAAATGACCTTCTTGTACAAGGATGGT
GCTAACTATGTTTTTATGGACCAACAAGACTACAGTCAAATTGAGATCCCCGAAAAGCAGTTAGAGTGGGAAAAGAACTT
TATCACTGAAGACAGTGAAGTTACTATTATTAGCTACCAAAGTGAAATTTTGGGCGTTAACCTACCCGAATTAGTGCCGA
TTGAAGTGGAATTTGCCGAAGAAGCAGTGCAAGGTAATACCGCTAACATGGCGCGTAAACGGGCTCGGTTAGTTTCGGGT
TACGAATTAGATGTGCCCCAGTTCATTCGTACTGGTGATAAGATTGTGATTTCCACCATTGACGGGAGCTATCGTGAACG
GTACAACAAGTAA

Upstream 100 bases:

>100_bases
TGCCCCAACCCTTAGCATTTCTGTTTGGTGGCTTAATGGCACTCAGGACAAGAAAGTACATTCGTTACCCTAAGAATTAA
GATTAAGATAGATAAAGCAT

Downstream 100 bases:

>100_bases
ATTAACTAGAACCCAAAGACGGATTGCAATTGTGGAGTTTATCTTCGCCACGCTGTTCTTTTTACCGAAAACTGCTGACC
AAATCCAAGCGGCCTTTTTG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MADMIEAKSLRSGQTIFGPNKEILLVLENTFNKTAMRQGIVKTKVKNLRTGAIVWIEFTGDKLEQVIIDKKKMTFLYKDG
ANYVFMDQQDYSQIEIPEKQLEWEKNFITEDSEVTIISYQSEILGVNLPELVPIEVEFAEEAVQGNTANMARKRARLVSG
YELDVPQFIRTGDKIVISTIDGSYRERYNK

Sequences:

>Translated_190_residues
MADMIEAKSLRSGQTIFGPNKEILLVLENTFNKTAMRQGIVKTKVKNLRTGAIVWIEFTGDKLEQVIIDKKKMTFLYKDG
ANYVFMDQQDYSQIEIPEKQLEWEKNFITEDSEVTIISYQSEILGVNLPELVPIEVEFAEEAVQGNTANMARKRARLVSG
YELDVPQFIRTGDKIVISTIDGSYRERYNK
>Mature_189_residues
ADMIEAKSLRSGQTIFGPNKEILLVLENTFNKTAMRQGIVKTKVKNLRTGAIVWIEFTGDKLEQVIIDKKKMTFLYKDGA
NYVFMDQQDYSQIEIPEKQLEWEKNFITEDSEVTIISYQSEILGVNLPELVPIEVEFAEEAVQGNTANMARKRARLVSGY
ELDVPQFIRTGDKIVISTIDGSYRERYNK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=27.5132275132275, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790590, Length=158, Percent_Identity=25.9493670886076, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EFP_MYCPN (P75085)

Other databases:

- EMBL:   U00089
- PIR:   S73451
- RefSeq:   NP_109717.1
- ProteinModelPortal:   P75085
- SMR:   P75085
- IntAct:   P75085
- GeneID:   876940
- GenomeReviews:   U00089_GR
- KEGG:   mpn:MPN029
- HOGENOM:   HBG303311
- OMA:   SYKGRAK
- ProtClustDB:   PRK00529
- BioCyc:   MPNE272634:MPN029-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21810; Mature: 21679

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADMIEAKSLRSGQTIFGPNKEILLVLENTFNKTAMRQGIVKTKVKNLRTGAIVWIEFTG
CCCCCCCHHCCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECC
DKLEQVIIDKKKMTFLYKDGANYVFMDQQDYSQIEIPEKQLEWEKNFITEDSEVTIISYQ
CHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEECCCHHHHHHHHHCCCCCCCEEEEEEC
SEILGVNLPELVPIEVEFAEEAVQGNTANMARKRARLVSGYELDVPQFIRTGDKIVISTI
CCEECCCCCCEEEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEEEC
DGSYRERYNK
CCHHHHHCCC
>Mature Secondary Structure 
ADMIEAKSLRSGQTIFGPNKEILLVLENTFNKTAMRQGIVKTKVKNLRTGAIVWIEFTG
CCCCCCHHCCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECC
DKLEQVIIDKKKMTFLYKDGANYVFMDQQDYSQIEIPEKQLEWEKNFITEDSEVTIISYQ
CHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEECCCHHHHHHHHHCCCCCCCEEEEEEC
SEILGVNLPELVPIEVEFAEEAVQGNTANMARKRARLVSGYELDVPQFIRTGDKIVISTI
CCEECCCCCCEEEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEEEC
DGSYRERYNK
CCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633; 11271496