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The map label for this gene is mtrH

Identifier: 161579524

GI number: 161579524

Start: 777753

End: 778712

Strand: Direct

Name: mtrH

Synonym: MJ0854

Alternate gene names: 161579524

Gene position: 777753-778712 (Clockwise)

Preceding gene: 15669043

Following gene: 15669045

Centisome position: 46.71

GC content: 39.79

Gene sequence:

>960_bases
ATGTTTAAGTTTGACAGAGAGCAAATGGTCGTTGAAATTGCGGGGAGAAAAATTGGAGGTCAGCCAGGAGAGTATCCTAC
AGCTTTAGCAGGGACTATATTCTATGCAAGACACAAAATTGTTGAAGATGAGAGAAAAGGTATCTTTGACAAAGCAGCGG
CAGAGGATTTAATTAACAAACAGGCAGAGATGGAAGACATTACTGGAAACCCAGCGTTAGTTCAGGTATTTGGAGGAACC
CCAGAGGCGTTAGTTAATTATATTGACTTTGTTGCTGAGGTTTGGGATGGTCCAATGTTATTGGACTCTACATCAGGAGA
AGCAAGAATGGCTGCTGCAAAGAGAGCTACTGAAGCTGGATATGCTAAGCAGTGTATTTATAACTCTATTAACGTTTCTA
TTGATGAGCAAGAATATCAGGTTTTAGTTGAAAGTGATTTGGAAGCATCAATTGTTTTATGTTTCGACCCAATGGACCCA
ACTGTTGAAGGAAAGATAAATGTCTTAACAAATGGTGGGAAAACAGCAGATAAGGGGATGTTAGAACTCGCTGAAAAAGC
AGGTATTAAGTATCCTTTAATCGATACAGCAGTTACACCATTAGGTAACGGAGCAGGAGCTGCTGTTAGAGCATCATTTG
CTGTTAAAGCACTATTTGGATATCCAGTAGGGAGTGGTATTCACAACATTCCATCAGCATGGGACTGGTTAAGAGAGTTT
AGAAAACAGTTAAGAGAAGCTGGAGAAAGAGAAAAAGCAAAAGATATTCACCACGTTTGTGATGTTGGAGCAAACTTAGT
CCAAGTTATGGCGTCAGGAGACTTTGTCCTTTATGGCCCAATTGACAATGCATATATGACATTCCCAGCAGTAGCTATGG
TTGATGCAATTATTGCAGAGGCAGCAAAAGAATTAGGAATTGAACCAATAGATACACATCCATTCAAGAAATTGGTCTAA

Upstream 100 bases:

>100_bases
CTTTCCTACATACTGCCAGCATTAATCAAAATCATACAAATATTGAGTTTAAAAGTACTTGTTCAACAATAAATATATAA
AAATTATGAGGTGGGAAATT

Downstream 100 bases:

>100_bases
TAAAATAAAAAATAAATAGTCTCTATTATTCTATTTTATTACTTTTTATAGTTTTGTAATTTTGATTCTTTTTAGAGTAA
TAGTATATAATTAGTGATAG

Product: tetrahydromethanopterin S-methyltransferase subunit H

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit H

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MFKFDREQMVVEIAGRKIGGQPGEYPTALAGTIFYARHKIVEDERKGIFDKAAAEDLINKQAEMEDITGNPALVQVFGGT
PEALVNYIDFVAEVWDGPMLLDSTSGEARMAAAKRATEAGYAKQCIYNSINVSIDEQEYQVLVESDLEASIVLCFDPMDP
TVEGKINVLTNGGKTADKGMLELAEKAGIKYPLIDTAVTPLGNGAGAAVRASFAVKALFGYPVGSGIHNIPSAWDWLREF
RKQLREAGEREKAKDIHHVCDVGANLVQVMASGDFVLYGPIDNAYMTFPAVAMVDAIIAEAAKELGIEPIDTHPFKKLV

Sequences:

>Translated_319_residues
MFKFDREQMVVEIAGRKIGGQPGEYPTALAGTIFYARHKIVEDERKGIFDKAAAEDLINKQAEMEDITGNPALVQVFGGT
PEALVNYIDFVAEVWDGPMLLDSTSGEARMAAAKRATEAGYAKQCIYNSINVSIDEQEYQVLVESDLEASIVLCFDPMDP
TVEGKINVLTNGGKTADKGMLELAEKAGIKYPLIDTAVTPLGNGAGAAVRASFAVKALFGYPVGSGIHNIPSAWDWLREF
RKQLREAGEREKAKDIHHVCDVGANLVQVMASGDFVLYGPIDNAYMTFPAVAMVDAIIAEAAKELGIEPIDTHPFKKLV
>Mature_319_residues
MFKFDREQMVVEIAGRKIGGQPGEYPTALAGTIFYARHKIVEDERKGIFDKAAAEDLINKQAEMEDITGNPALVQVFGGT
PEALVNYIDFVAEVWDGPMLLDSTSGEARMAAAKRATEAGYAKQCIYNSINVSIDEQEYQVLVESDLEASIVLCFDPMDP
TVEGKINVLTNGGKTADKGMLELAEKAGIKYPLIDTAVTPLGNGAGAAVRASFAVKALFGYPVGSGIHNIPSAWDWLREF
RKQLREAGEREKAKDIHHVCDVGANLVQVMASGDFVLYGPIDNAYMTFPAVAMVDAIIAEAAKELGIEPIDTHPFKKLV

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl grou

COG id: COG1962

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit H

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRH_METJA (Q58264)

Other databases:

- EMBL:   L77117
- PIR:   F64406
- RefSeq:   NP_247848.2
- ProteinModelPortal:   Q58264
- GeneID:   1451742
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0854
- NMPDR:   fig|243232.1.peg.885
- TIGR:   MJ0854
- HOGENOM:   HBG512918
- OMA:   YARHKIV
- ProtClustDB:   PRK00979
- BioCyc:   MJAN243232:MJ_0854-MONOMER
- BRENDA:   2.1.1.86
- GO:   GO:0015948
- HAMAP:   MF_01501
- InterPro:   IPR011005
- InterPro:   IPR002856
- InterPro:   IPR000489
- Gene3D:   G3DSA:3.20.20.20
- ProDom:   PD009948
- TIGRFAMs:   TIGR01114

Pfam domain/function: PF02007 MtrH; SSF51717 DHP_synth_like

EC number: =2.1.1.86

Molecular weight: Translated: 34603; Mature: 34603

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFDREQMVVEIAGRKIGGQPGEYPTALAGTIFYARHKIVEDERKGIFDKAAAEDLINK
CCCCCHHHHHHHHHCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
QAEMEDITGNPALVQVFGGTPEALVNYIDFVAEVWDGPMLLDSTSGEARMAAAKRATEAG
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHH
YAKQCIYNSINVSIDEQEYQVLVESDLEASIVLCFDPMDPTVEGKINVLTNGGKTADKGM
HHHHHHHHCCCEEECHHHHHHHEECCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHH
LELAEKAGIKYPLIDTAVTPLGNGAGAAVRASFAVKALFGYPVGSGIHNIPSAWDWLREF
HHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RKQLREAGEREKAKDIHHVCDVGANLVQVMASGDFVLYGPIDNAYMTFPAVAMVDAIIAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHH
AAKELGIEPIDTHPFKKLV
HHHHCCCCCCCCCCHHHCC
>Mature Secondary Structure
MFKFDREQMVVEIAGRKIGGQPGEYPTALAGTIFYARHKIVEDERKGIFDKAAAEDLINK
CCCCCHHHHHHHHHCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
QAEMEDITGNPALVQVFGGTPEALVNYIDFVAEVWDGPMLLDSTSGEARMAAAKRATEAG
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHH
YAKQCIYNSINVSIDEQEYQVLVESDLEASIVLCFDPMDPTVEGKINVLTNGGKTADKGM
HHHHHHHHCCCEEECHHHHHHHEECCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHH
LELAEKAGIKYPLIDTAVTPLGNGAGAAVRASFAVKALFGYPVGSGIHNIPSAWDWLREF
HHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RKQLREAGEREKAKDIHHVCDVGANLVQVMASGDFVLYGPIDNAYMTFPAVAMVDAIIAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHH
AAKELGIEPIDTHPFKKLV
HHHHCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087