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The map label for this gene is yfdZ [C]

Identifier: 15669581

GI number: 15669581

Start: 1338520

End: 1339776

Strand: Reverse

Name: yfdZ [C]

Synonym: MJ1391

Alternate gene names: 15669581

Gene position: 1339776-1338520 (Counterclockwise)

Preceding gene: 15669589

Following gene: 15669580

Centisome position: 80.47

GC content: 36.28

Gene sequence:

>1257_bases
ATGGAAAGTTACATACAAAACTTATTTGCTGAGAGAATTGGTGGAAAGAAGTTTGGGAAAGAAGATGTAATTTACAAGTT
TGAGAAAATTAAGAGAGCTAAGCAAGAGGCAATGAAAAGACACCCTGATATGGAATTAATTGATATGGGTGTTGGAGAAC
CAGATGAGATGGCAGACCCGGAGGTTATAAGAGTTTTGTGTGAGGAGGCTAAAAAATGGGAAAACAGAGGATATGCGGAT
AACGGAATACAGGAGTTAAAAGATGCCGTTCCTCCATACATGGAGAAGGTTTATGGAGTTAAGGATATAGACCCAGTTAA
TGAGGTTATACACTCAATAGGTTCAAAACCAGCTTTAGCTTATATAACATCAGCATTTATAAACCCTGGAGATGTTTGCC
TAATGACAGTCCCTGGCTATCCAGTTACAGCAACACACACAAAATGGTATGGGGGAGAGGTTTATAATCTCCCATTATTA
GAGGAGAATGACTTCTTACCAGATTTAGAGAGCATTCCAGAAGATATCAAGAAGAGAGCAAAGATATTATATCTCAATTA
TCCAAACAACCCTACTGGAGCACAAGCTACAAAGAAATTCTACAAAGAGGTTGTTGATTTTGCTTTTGAAAATGAGGTTA
TCGTTGTTCAAGATGCTGCTTATGGAGCTTTGGTTTATGATGGAAAGCCTCTTTCATTCTTATCAGTTAAAGATGCTAAG
GAGGTTGGAGTTGAAATCCATAGCTTTTCAAAGGCATTCAACATGACCGGTTGGAGATTGGCATTTTTGGTTGGGAATGA
ACTTATAATTAAAGCGTTTGCAACAGTTAAAGACAACTTTGATAGTGGGCAGTTCATCCCAATCCAAAAAGCTGGAATTT
ATTGTTTGCAACATCCAGAAATTACAGAAAGAGTTAGACAGAAGTATGAGAGAAGGTTAAGAAAGATGGTTAAGATATTA
AATGAAGTTGGATTTAAAGCAAGAATGCCTGGAGGAACTTTTTATTTATATGTAAAATCACCAACAAAAGCTAATGGTAT
TGAATTTAAAACAGCTGAGGATTTCTCCCAATACTTAATTAAAGAAAAACTTATTTCAACAGTTCCATGGGATGATGCAG
GGCATTATTTAAGATTAGCAGCATGCTTTGTTGCTAAAGATGAGAACGGCAATCCAACAACTGAAGAGAAGTATGAAGAT
ATGGTATTAGAGGAGTTTAAGAGAAGATTGGAGGGAATGGATTTAGAATTTGAATAA

Upstream 100 bases:

>100_bases
TAAAATTAAAAAATACCTTACTAAAGGAAGGCATTCATTACTACCCATATATTCTTTTAAAATGCTCCGCAAAAACTAAA
AATGCCAATTTGGTGATAAA

Downstream 100 bases:

>100_bases
TTGATTTTTATTTATTTTAAATTTTTCATATTTTTATTTTTACTATTCTTTATTTATATATTCGGATTAATAAAAATATC
TAAAACCTGTTCTAAAATTT

Product: aspartate aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MESYIQNLFAERIGGKKFGKEDVIYKFEKIKRAKQEAMKRHPDMELIDMGVGEPDEMADPEVIRVLCEEAKKWENRGYAD
NGIQELKDAVPPYMEKVYGVKDIDPVNEVIHSIGSKPALAYITSAFINPGDVCLMTVPGYPVTATHTKWYGGEVYNLPLL
EENDFLPDLESIPEDIKKRAKILYLNYPNNPTGAQATKKFYKEVVDFAFENEVIVVQDAAYGALVYDGKPLSFLSVKDAK
EVGVEIHSFSKAFNMTGWRLAFLVGNELIIKAFATVKDNFDSGQFIPIQKAGIYCLQHPEITERVRQKYERRLRKMVKIL
NEVGFKARMPGGTFYLYVKSPTKANGIEFKTAEDFSQYLIKEKLISTVPWDDAGHYLRLAACFVAKDENGNPTTEEKYED
MVLEEFKRRLEGMDLEFE

Sequences:

>Translated_418_residues
MESYIQNLFAERIGGKKFGKEDVIYKFEKIKRAKQEAMKRHPDMELIDMGVGEPDEMADPEVIRVLCEEAKKWENRGYAD
NGIQELKDAVPPYMEKVYGVKDIDPVNEVIHSIGSKPALAYITSAFINPGDVCLMTVPGYPVTATHTKWYGGEVYNLPLL
EENDFLPDLESIPEDIKKRAKILYLNYPNNPTGAQATKKFYKEVVDFAFENEVIVVQDAAYGALVYDGKPLSFLSVKDAK
EVGVEIHSFSKAFNMTGWRLAFLVGNELIIKAFATVKDNFDSGQFIPIQKAGIYCLQHPEITERVRQKYERRLRKMVKIL
NEVGFKARMPGGTFYLYVKSPTKANGIEFKTAEDFSQYLIKEKLISTVPWDDAGHYLRLAACFVAKDENGNPTTEEKYED
MVLEEFKRRLEGMDLEFE
>Mature_418_residues
MESYIQNLFAERIGGKKFGKEDVIYKFEKIKRAKQEAMKRHPDMELIDMGVGEPDEMADPEVIRVLCEEAKKWENRGYAD
NGIQELKDAVPPYMEKVYGVKDIDPVNEVIHSIGSKPALAYITSAFINPGDVCLMTVPGYPVTATHTKWYGGEVYNLPLL
EENDFLPDLESIPEDIKKRAKILYLNYPNNPTGAQATKKFYKEVVDFAFENEVIVVQDAAYGALVYDGKPLSFLSVKDAK
EVGVEIHSFSKAFNMTGWRLAFLVGNELIIKAFATVKDNFDSGQFIPIQKAGIYCLQHPEITERVRQKYERRLRKMVKIL
NEVGFKARMPGGTFYLYVKSPTKANGIEFKTAEDFSQYLIKEKLISTVPWDDAGHYLRLAACFVAKDENGNPTTEEKYED
MVLEEFKRRLEGMDLEFE

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI56713256, Length=362, Percent_Identity=25.1381215469613, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI56713254, Length=362, Percent_Identity=25.1381215469613, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI95147551, Length=340, Percent_Identity=24.7058823529412, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI169881279, Length=340, Percent_Identity=24.7058823529412, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI169881281, Length=286, Percent_Identity=25.1748251748252, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4507369, Length=352, Percent_Identity=22.1590909090909, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788722, Length=366, Percent_Identity=33.0601092896175, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1788627, Length=341, Percent_Identity=24.9266862170088, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786816, Length=327, Percent_Identity=22.3241590214067, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=354, Percent_Identity=26.8361581920904, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=354, Percent_Identity=26.8361581920904, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=380, Percent_Identity=23.9473684210526, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=23.5294117647059, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI28573069, Length=399, Percent_Identity=21.8045112781955, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24646114, Length=399, Percent_Identity=21.8045112781955, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573067, Length=399, Percent_Identity=21.8045112781955, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573065, Length=399, Percent_Identity=21.8045112781955, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI18859735, Length=351, Percent_Identity=22.5071225071225, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1391_METJA (Q58786)

Other databases:

- EMBL:   L77117
- PIR:   F64473
- RefSeq:   NP_248394.1
- ProteinModelPortal:   Q58786
- SMR:   Q58786
- GeneID:   1452294
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1391
- NMPDR:   fig|243232.1.peg.1431
- TIGR:   MJ1391
- HOGENOM:   HBG645860
- OMA:   HPEITER
- ProtClustDB:   PRK06290
- BioCyc:   MetaCyc:MONOMER-15639
- BioCyc:   MJAN243232:MJ_1391-MONOMER
- GO:   GO:0005737
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: 2.6.1.1

Molecular weight: Translated: 47709; Mature: 47709

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESYIQNLFAERIGGKKFGKEDVIYKFEKIKRAKQEAMKRHPDMELIDMGVGEPDEMADP
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
EVIRVLCEEAKKWENRGYADNGIQELKDAVPPYMEKVYGVKDIDPVNEVIHSIGSKPALA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCHHH
YITSAFINPGDVCLMTVPGYPVTATHTKWYGGEVYNLPLLEENDFLPDLESIPEDIKKRA
HHHHHHCCCCCEEEEECCCCCEEECCCEECCCEEEECCCCCCCCCCCCHHHHHHHHHHCC
KILYLNYPNNPTGAQATKKFYKEVVDFAFENEVIVVQDAAYGALVYDGKPLSFLSVKDAK
EEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCEEEECCCHH
EVGVEIHSFSKAFNMTGWRLAFLVGNELIIKAFATVKDNFDSGQFIPIQKAGIYCLQHPE
HHCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCH
ITERVRQKYERRLRKMVKILNEVGFKARMPGGTFYLYVKSPTKANGIEFKTAEDFSQYLI
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCEEECCHHHHHHHHH
KEKLISTVPWDDAGHYLRLAACFVAKDENGNPTTEEKYEDMVLEEFKRRLEGMDLEFE
HHHHHHCCCCCCCCHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MESYIQNLFAERIGGKKFGKEDVIYKFEKIKRAKQEAMKRHPDMELIDMGVGEPDEMADP
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
EVIRVLCEEAKKWENRGYADNGIQELKDAVPPYMEKVYGVKDIDPVNEVIHSIGSKPALA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCHHH
YITSAFINPGDVCLMTVPGYPVTATHTKWYGGEVYNLPLLEENDFLPDLESIPEDIKKRA
HHHHHHCCCCCEEEEECCCCCEEECCCEECCCEEEECCCCCCCCCCCCHHHHHHHHHHCC
KILYLNYPNNPTGAQATKKFYKEVVDFAFENEVIVVQDAAYGALVYDGKPLSFLSVKDAK
EEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCEEEECCCHH
EVGVEIHSFSKAFNMTGWRLAFLVGNELIIKAFATVKDNFDSGQFIPIQKAGIYCLQHPE
HHCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCH
ITERVRQKYERRLRKMVKILNEVGFKARMPGGTFYLYVKSPTKANGIEFKTAEDFSQYLI
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCEEECCHHHHHHHHH
KEKLISTVPWDDAGHYLRLAACFVAKDENGNPTTEEKYEDMVLEEFKRRLEGMDLEFE
HHHHHHCCCCCCCCHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087