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The map label for this gene is arsR [C]

Identifier: 15669515

GI number: 15669515

Start: 1275423

End: 1275692

Strand: Direct

Name: arsR [C]

Synonym: MJ1325

Alternate gene names: 15669515

Gene position: 1275423-1275692 (Clockwise)

Preceding gene: 15669514

Following gene: 15669516

Centisome position: 76.6

GC content: 33.33

Gene sequence:

>270_bases
ATGGAGAAGTACGAAAAAGCGGCAGAAATTTTCAAGGCATTTGGAGACCCAACAAGATTGATGATTTTAAAGTTATTGGC
TGAAAATGGAAGCATGTGCGTTTGTAAAATAATAGATGAGCTAAAAAAGCCACAGCCAACAATCTCACACCACTTAAACA
TCTTAAAAAAGGCTGGAATAGTTAAAGCAAGAAAAGAAGGAACATGGAATTTCTACTACATCGTAGATGACAGAGTTAAA
GAGATTATTAAATTAGTTGATGAATTATAA

Upstream 100 bases:

>100_bases
TAAAGTTGATTGCAATTTAAACATCAATATGGAAAAATATATGTCTAAATATATACTTAAACATTTTAATAGAAATAAAA
AATAATCACGAGGGATAACA

Downstream 100 bases:

>100_bases
CCATAGGAGGAGACCTCCTATTGGGATACCTCCCGTCCATTAAGTTGGGGCTTTCAGCCCCAATTAATGTCCAAGCTCTA
TAAAGAACAAGAATGTGACT

Product: cadmium resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MEKYEKAAEIFKAFGDPTRLMILKLLAENGSMCVCKIIDELKKPQPTISHHLNILKKAGIVKARKEGTWNFYYIVDDRVK
EIIKLVDEL

Sequences:

>Translated_89_residues
MEKYEKAAEIFKAFGDPTRLMILKLLAENGSMCVCKIIDELKKPQPTISHHLNILKKAGIVKARKEGTWNFYYIVDDRVK
EIIKLVDEL
>Mature_89_residues
MEKYEKAAEIFKAFGDPTRLMILKLLAENGSMCVCKIIDELKKPQPTISHHLNILKKAGIVKARKEGTWNFYYIVDDRVK
EIIKLVDEL

Specific function: Transcriptional Repressor For The Arsefg Operon. Arse Is A Trans-Acting Regulatory Protein Which Controls Its Own Expression. The Repressive Effect Of Arse Is Alleviated By Oxyions Of +III Oxidation State Of Arsenic, Antimony, And Bismuth, As Well As Arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789916, Length=80, Percent_Identity=38.75, Blast_Score=66, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1325_METJA (Q58721)

Other databases:

- EMBL:   L77117
- PIR:   D64465
- RefSeq:   NP_248325.1
- ProteinModelPortal:   Q58721
- SMR:   Q58721
- GeneID:   1452227
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1325
- NMPDR:   fig|243232.1.peg.1362
- TIGR:   MJ1325
- HOGENOM:   HBG742701
- OMA:   MIANETK
- ProtClustDB:   CLSK876531
- BioCyc:   MJAN243232:MJ_1325-MONOMER
- GO:   GO:0005622
- InterPro:   IPR001845
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00778
- SMART:   SM00418

Pfam domain/function: PF01022 HTH_5

EC number: NA

Molecular weight: Translated: 10292; Mature: 10292

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00846 HTH_ARSR_1; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKYEKAAEIFKAFGDPTRLMILKLLAENGSMCVCKIIDELKKPQPTISHHLNILKKAGI
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHCC
VKARKEGTWNFYYIVDDRVKEIIKLVDEL
HHCCCCCCEEEEEEECHHHHHHHHHHHCC
>Mature Secondary Structure
MEKYEKAAEIFKAFGDPTRLMILKLLAENGSMCVCKIIDELKKPQPTISHHLNILKKAGI
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHCC
VKARKEGTWNFYYIVDDRVKEIIKLVDEL
HHCCCCCCEEEEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087