Click here to switch to the map view.

The map label for this gene is ttdA [C]

Identifier: 15669484

GI number: 15669484

Start: 1241972

End: 1242829

Strand: Reverse

Name: ttdA [C]

Synonym: MJ1294

Alternate gene names: 15669484

Gene position: 1242829-1241972 (Counterclockwise)

Preceding gene: 15669485

Following gene: 15669480

Centisome position: 74.65

GC content: 32.52

Gene sequence:

>858_bases
ATGAAAATCTCCGATGTTGTTGTTGAATTATTTAGAGAGGCAGCTATTTATCTACCAGAAGATGTAAAAAATGCTTTAGA
AGAAGCATATAAAAAAGAAAGTAGTGAAATATCAAAAAACACATTAAAAGCAATCATAGAAAATAACAAAATAGCTGAAG
AAACGCAAGTTCCTCTATGTCAAGATACTGGTGTCCCAATAGTATTTTTGAAAATTGGAAAGAATATAAATTCATCAGAA
ATAATGAAAATCATTGAAGAAATAAAAGAAGGAGTAAAAAAAGCAACGGAAGAGGTTCCTTTAAGACCTAATGTAGTTCA
TCCTTTAACAAGAGAGAATTTTAAAACAAATGTTGGCTTAAATTCCCCATTCATAAATATTGAGTTTGATGAAAGCTTAG
ATAGAGAGATTGAGATAATTGCATTTCCAAAAGGGGCAGGAAGCGAAAACATGAGTGCTTTAAAGATGTTAAAGCCCTCT
GATGGAATAGAGGGGATAAAAAACTTTGTTTTAGAAACAATTGCAAATGCTGGAGGAAAGCCATGTCCTCCAATAGTTGT
TGGAATAGGCATTGGGGGAACTGCTGATGTAGCATTAAAATTAGCTAAAAAAGCACTGCTAAGAAAAATAGGAGAGAGAC
ATAGGGATAAAGAAATAGCTAATCTTGAAAAAGAGTTGTTAGAAAAAATAAATAGCTTAGGAATTGGAGCAATGGGTTTA
GGAGGGGATATAACTGCTTTAGATGTTTTTATTGAGATTGCTGGATGCCATACAGCTTCTTTACCTGTAGGAATTTGTAT
TCAATGCTGGGCAGATAGAAGGGCAATTAAAAGAATAAAATTGGATGCTAAATTATAA

Upstream 100 bases:

>100_bases
AAAAAAGGTTGGTTTAGGGGCAGGATTAACCAATAAAGAGTTGGAAAATACTTTATTGCATTATCCAAAGGAGCTTTTAA
AGAGAATTTGAGGTGAAAGA

Downstream 100 bases:

>100_bases
GTGTCTTTCAAACTTCTTAGATAACTAACGCACTAATAAACGCCTTCCTTTGGAGGTGTTCAAACCTTCTTCAATAAATT
TTATTGATTTGAAAAAAATA

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKISDVVVELFREAAIYLPEDVKNALEEAYKKESSEISKNTLKAIIENNKIAEETQVPLCQDTGVPIVFLKIGKNINSSE
IMKIIEEIKEGVKKATEEVPLRPNVVHPLTRENFKTNVGLNSPFINIEFDESLDREIEIIAFPKGAGSENMSALKMLKPS
DGIEGIKNFVLETIANAGGKPCPPIVVGIGIGGTADVALKLAKKALLRKIGERHRDKEIANLEKELLEKINSLGIGAMGL
GGDITALDVFIEIAGCHTASLPVGICIQCWADRRAIKRIKLDAKL

Sequences:

>Translated_285_residues
MKISDVVVELFREAAIYLPEDVKNALEEAYKKESSEISKNTLKAIIENNKIAEETQVPLCQDTGVPIVFLKIGKNINSSE
IMKIIEEIKEGVKKATEEVPLRPNVVHPLTRENFKTNVGLNSPFINIEFDESLDREIEIIAFPKGAGSENMSALKMLKPS
DGIEGIKNFVLETIANAGGKPCPPIVVGIGIGGTADVALKLAKKALLRKIGERHRDKEIANLEKELLEKINSLGIGAMGL
GGDITALDVFIEIAGCHTASLPVGICIQCWADRRAIKRIKLDAKL
>Mature_285_residues
MKISDVVVELFREAAIYLPEDVKNALEEAYKKESSEISKNTLKAIIENNKIAEETQVPLCQDTGVPIVFLKIGKNINSSE
IMKIIEEIKEGVKKATEEVPLRPNVVHPLTRENFKTNVGLNSPFINIEFDESLDREIEIIAFPKGAGSENMSALKMLKPS
DGIEGIKNFVLETIANAGGKPCPPIVVGIGIGGTADVALKLAKKALLRKIGERHRDKEIANLEKELLEKINSLGIGAMGL
GGDITALDVFIEIAGCHTASLPVGICIQCWADRRAIKRIKLDAKL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family

Homologues:

Organism=Escherichia coli, GI1789442, Length=283, Percent_Identity=33.2155477031802, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790564, Length=284, Percent_Identity=30.6338028169014, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787897, Length=282, Percent_Identity=30.1418439716312, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FUMA_METJA (Q58690)

Other databases:

- EMBL:   L77117
- PIR:   E64461
- RefSeq:   NP_248294.1
- ProteinModelPortal:   Q58690
- GeneID:   1452196
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1294
- NMPDR:   fig|243232.1.peg.1331
- TIGR:   MJ1294
- HOGENOM:   HBG548096
- OMA:   GCHTASL
- ProtClustDB:   PRK06246
- BioCyc:   MJAN243232:MJ_1294-MONOMER
- BRENDA:   4.2.1.2
- InterPro:   IPR004646
- TIGRFAMs:   TIGR00722

Pfam domain/function: PF05681 Fumerase

EC number: =4.2.1.2

Molecular weight: Translated: 31089; Mature: 31089

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISDVVVELFREAAIYLPEDVKNALEEAYKKESSEISKNTLKAIIENNKIAEETQVPLC
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
QDTGVPIVFLKIGKNINSSEIMKIIEEIKEGVKKATEEVPLRPNVVHPLTRENFKTNVGL
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
NSPFINIEFDESLDREIEIIAFPKGAGSENMSALKMLKPSDGIEGIKNFVLETIANAGGK
CCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
PCPPIVVGIGIGGTADVALKLAKKALLRKIGERHRDKEIANLEKELLEKINSLGIGAMGL
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
GGDITALDVFIEIAGCHTASLPVGICIQCWADRRAIKRIKLDAKL
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKISDVVVELFREAAIYLPEDVKNALEEAYKKESSEISKNTLKAIIENNKIAEETQVPLC
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
QDTGVPIVFLKIGKNINSSEIMKIIEEIKEGVKKATEEVPLRPNVVHPLTRENFKTNVGL
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
NSPFINIEFDESLDREIEIIAFPKGAGSENMSALKMLKPSDGIEGIKNFVLETIANAGGK
CCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
PCPPIVVGIGIGGTADVALKLAKKALLRKIGERHRDKEIANLEKELLEKINSLGIGAMGL
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
GGDITALDVFIEIAGCHTASLPVGICIQCWADRRAIKRIKLDAKL
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087