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The map label for this gene is queD

Identifier: 15669458

GI number: 15669458

Start: 1216142

End: 1216633

Strand: Direct

Name: queD

Synonym: MJ1272

Alternate gene names: 15669458

Gene position: 1216142-1216633 (Clockwise)

Preceding gene: 15669457

Following gene: 15669459

Centisome position: 73.04

GC content: 30.49

Gene sequence:

>492_bases
ATGATGTTGGAGTTAAATGGACTACATGCAGGTTTAAGGTTTTCATCAGCCCATATTGTATTTGGACATCCAACTTGTGG
GGTTATACATGGACATTCTTATTATGTAGATGTAAAACTTTATGGAGAGAGGGCTGGAGACTTCAAATTTGTATGTGATT
TTAAAATAATTAAAAAAATTGTAAAAGAGATTTGTGATGAATTAGACCACAAATTAATACTTCCAAAAAATCATGAACAT
GTATATTATGAGTTAAGAGATAAAACCCTATACTTTAAATATGAGAATAAAGAATACAGTATTCCTGTTGAGGATGTCAT
TTTATTACCTATTCCATCAACTACAGCTGAAGATTTAGCAATATATTTTGCCAATGAAATAGCAGATAGATTAAAAAATC
TCGGTTTTTCTAATATAAATTGGATAGAGGTCTCTATCAATGAGGGAATAGGACAGGGAGCTTGCTATAGAAAATACTTA
GAGGTGAAATAA

Upstream 100 bases:

>100_bases
AAACACCAAAAGGTTTAGAAAGAGAAATATTGGCTGCTGGTGGCTTAGTCAATTATTTAAAAAAGAGAAAACTAATACAA
TCAAAAAAAGGTGTAAAAAC

Downstream 100 bases:

>100_bases
TGGAAAGAATCTTAGAGAAGGTTAGAGCAAAGTCAGAGATTCCAGTATATGACAAATCAATTGAGAATGTTTTGTCAGCT
ATTTTAACAACCAACGATTT

Product: hypothetical protein

Products: NA

Alternate protein names: CPH4 synthase; Archaeosine biosynthesis protein queD

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MMLELNGLHAGLRFSSAHIVFGHPTCGVIHGHSYYVDVKLYGERAGDFKFVCDFKIIKKIVKEICDELDHKLILPKNHEH
VYYELRDKTLYFKYENKEYSIPVEDVILLPIPSTTAEDLAIYFANEIADRLKNLGFSNINWIEVSINEGIGQGACYRKYL
EVK

Sequences:

>Translated_163_residues
MMLELNGLHAGLRFSSAHIVFGHPTCGVIHGHSYYVDVKLYGERAGDFKFVCDFKIIKKIVKEICDELDHKLILPKNHEH
VYYELRDKTLYFKYENKEYSIPVEDVILLPIPSTTAEDLAIYFANEIADRLKNLGFSNINWIEVSINEGIGQGACYRKYL
EVK
>Mature_163_residues
MMLELNGLHAGLRFSSAHIVFGHPTCGVIHGHSYYVDVKLYGERAGDFKFVCDFKIIKKIVKEICDELDHKLILPKNHEH
VYYELRDKTLYFKYENKEYSIPVEDVILLPIPSTTAEDLAIYFANEIADRLKNLGFSNINWIEVSINEGIGQGACYRKYL
EVK

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUED_METJA (Q58668)

Other databases:

- EMBL:   L77117
- PIR:   G64458
- RefSeq:   NP_248268.1
- ProteinModelPortal:   Q58668
- SMR:   Q58668
- GeneID:   1452170
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1272
- NMPDR:   fig|243232.1.peg.1305
- TIGR:   MJ1272
- HOGENOM:   HBG727155
- OMA:   ELNGLHA
- ProtClustDB:   CLSK876513
- BioCyc:   MJAN243232:MJ_1272-MONOMER
- BRENDA:   4.2.3.12
- InterPro:   IPR007116
- InterPro:   IPR007115
- PANTHER:   PTHR12589
- TIGRFAMs:   TIGR00039

Pfam domain/function: PF01242 PTPS

EC number: NA

Molecular weight: Translated: 18816; Mature: 18816

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 26-26 ACT_SITE 70-70 ACT_SITE 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLELNGLHAGLRFSSAHIVFGHPTCGVIHGHSYYVDVKLYGERAGDFKFVCDFKIIKKI
CEEEECCCCCCEEECCEEEEEECCCEEEEECCEEEEEEEEEECCCCCEEEEECHHHHHHH
VKEICDELDHKLILPKNHEHVYYELRDKTLYFKYENKEYSIPVEDVILLPIPSTTAEDLA
HHHHHHHCCCEEECCCCCCEEEEEEECCEEEEEECCCEECCCHHHEEEEECCCCCHHHHH
IYFANEIADRLKNLGFSNINWIEVSINEGIGQGACYRKYLEVK
EEHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHEEEECC
>Mature Secondary Structure
MMLELNGLHAGLRFSSAHIVFGHPTCGVIHGHSYYVDVKLYGERAGDFKFVCDFKIIKKI
CEEEECCCCCCEEECCEEEEEECCCEEEEECCEEEEEEEEEECCCCCEEEEECHHHHHHH
VKEICDELDHKLILPKNHEHVYYELRDKTLYFKYENKEYSIPVEDVILLPIPSTTAEDLA
HHHHHHHCCCEEECCCCCCEEEEEEECCEEEEEECCCEECCCHHHEEEEECCCCCHHHHH
IYFANEIADRLKNLGFSNINWIEVSINEGIGQGACYRKYLEVK
EEHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087