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The map label for this gene is cofD

Identifier: 15669442

GI number: 15669442

Start: 1198608

End: 1199543

Strand: Direct

Name: cofD

Synonym: MJ1256

Alternate gene names: 15669442

Gene position: 1198608-1199543 (Clockwise)

Preceding gene: 15669441

Following gene: 15669443

Centisome position: 71.99

GC content: 32.69

Gene sequence:

>936_bases
GTGATATTTGTGATTACTGTATTGTCAGGAGGAACTGGGACACCAAAGTTATTGCAGGGTTTAAAAAGGGTTGTTAATAA
TGAAGAGTTGGCTGTTATTGTTAATACTGGTGAAGATACTTGGATAGGAGATTTATATCTATCTCCTGATGTTGATACCG
TTCTATATACCTTAGCAGATTTGATTAATGAAGAGACATGGTATGGGGTTAAGGAAGATACTTTTTATACTCATGAGCAA
TTAAAAAATCTTGGATTTGATGAAGTTTTAAGGATAGGGGATAAAGATAGAGCCTTAAAAATGCATAAAACTTATTATTT
AAAGAGGGGACATAAACTCTCAGAAGTTGTAGATATGGAGAAAGTAGCTTTGGGGATTAAAGCTAAAGTAATCCCAATGA
CTGATGATAGGGTTGAGACAAAAATTTTAGCAAAAGTTGATGGAAAGGTTGATTTATTAAAGTTTCATGACTTCTGGGTT
AAGAGAAAGGGGGACGTTGAGGTTTTAGATGTTATTTATGAAAACTCTCTATATGCTAAACCTTGTGAAAAGGCAGTTGA
GGCCATAAAAAATAGTGACCTTGTTATTATAGGGCCCTCAAATCCAATAACTTCCATAGGTCCAATTTTAAGTTTAAATG
GAATTAAAGAGCTATTAAAAGATAAAAAGGTTGTGGTTGTTTCGCCAATAGTTGGAAATTCTGCTGTTTCAGGTCCTGCG
GGTAAATTAATGAAAGCTAAAGGTTATGATGTCTCTGTTAAAGGGATTTATGAGTTCTATAAAGACATAGTTGATGTTTT
AGTAATAGATAATGTTGATAAAGAGATAGCTAAAGAAATACCTTGTGAGGTTTTAATAACCAACACAATTATGAAAACAT
TGGATGATAAAGTTAGATTAGCTAAAAATATTATTGAGTTCTGTGGGTCTTTATGA

Upstream 100 bases:

>100_bases
TAATAGATGAATTTTTTGAAACAAGAAAAAATATAAGAAAATACTACTTAACTGATAGAATAGCTAATAAGTTAATTAAT
AAATTCAAGCTAAAGATTAG

Downstream 100 bases:

>100_bases
AGCCGGTAGCTTTAGTTACAACAAAACCAGGATTTGAGCCACAATTAAGAGAGGAGCTAAATAAATTACCAATAAAAAAG
AAAATTCTCTGGACACCATT

Product: LPPG:FO 2-phospho-L-lactate transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIFVITVLSGGTGTPKLLQGLKRVVNNEELAVIVNTGEDTWIGDLYLSPDVDTVLYTLADLINEETWYGVKEDTFYTHEQ
LKNLGFDEVLRIGDKDRALKMHKTYYLKRGHKLSEVVDMEKVALGIKAKVIPMTDDRVETKILAKVDGKVDLLKFHDFWV
KRKGDVEVLDVIYENSLYAKPCEKAVEAIKNSDLVIIGPSNPITSIGPILSLNGIKELLKDKKVVVVSPIVGNSAVSGPA
GKLMKAKGYDVSVKGIYEFYKDIVDVLVIDNVDKEIAKEIPCEVLITNTIMKTLDDKVRLAKNIIEFCGSL

Sequences:

>Translated_311_residues
MIFVITVLSGGTGTPKLLQGLKRVVNNEELAVIVNTGEDTWIGDLYLSPDVDTVLYTLADLINEETWYGVKEDTFYTHEQ
LKNLGFDEVLRIGDKDRALKMHKTYYLKRGHKLSEVVDMEKVALGIKAKVIPMTDDRVETKILAKVDGKVDLLKFHDFWV
KRKGDVEVLDVIYENSLYAKPCEKAVEAIKNSDLVIIGPSNPITSIGPILSLNGIKELLKDKKVVVVSPIVGNSAVSGPA
GKLMKAKGYDVSVKGIYEFYKDIVDVLVIDNVDKEIAKEIPCEVLITNTIMKTLDDKVRLAKNIIEFCGSL
>Mature_311_residues
MIFVITVLSGGTGTPKLLQGLKRVVNNEELAVIVNTGEDTWIGDLYLSPDVDTVLYTLADLINEETWYGVKEDTFYTHEQ
LKNLGFDEVLRIGDKDRALKMHKTYYLKRGHKLSEVVDMEKVALGIKAKVIPMTDDRVETKILAKVDGKVDLLKFHDFWV
KRKGDVEVLDVIYENSLYAKPCEKAVEAIKNSDLVIIGPSNPITSIGPILSLNGIKELLKDKKVVVVSPIVGNSAVSGPA
GKLMKAKGYDVSVKGIYEFYKDIVDVLVIDNVDKEIAKEIPCEVLITNTIMKTLDDKVRLAKNIIEFCGSL

Specific function: Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F42

COG id: COG0391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COFD_METJA (Q58653)

Other databases:

- EMBL:   L77117
- PIR:   G64456
- RefSeq:   NP_248252.1
- ProteinModelPortal:   Q58653
- SMR:   Q58653
- GeneID:   1452154
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1256
- NMPDR:   fig|243232.1.peg.1289
- TIGR:   MJ1256
- HOGENOM:   HBG374278
- OMA:   SNPITSI
- ProtClustDB:   PRK13606
- BioCyc:   MetaCyc:MONOMER-12181
- BioCyc:   MJAN243232:MJ_1256-MONOMER
- HAMAP:   MF_01257
- InterPro:   IPR002882
- InterPro:   IPR010115
- TIGRFAMs:   TIGR01819

Pfam domain/function: PF01933 UPF0052

EC number: NA

Molecular weight: Translated: 34600; Mature: 34600

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFVITVLSGGTGTPKLLQGLKRVVNNEELAVIVNTGEDTWIGDLYLSPDVDTVLYTLAD
CEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHH
LINEETWYGVKEDTFYTHEQLKNLGFDEVLRIGDKDRALKMHKTYYLKRGHKLSEVVDME
HHCCHHCCCCCCCCCHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
KVALGIKAKVIPMTDDRVETKILAKVDGKVDLLKFHDFWVKRKGDVEVLDVIYENSLYAK
HHHHCCEEEEEECCCCCHHHEEEEEECCCEEEEEEHHHHHCCCCCHHEEEEHHCCCCCCC
PCEKAVEAIKNSDLVIIGPSNPITSIGPILSLNGIKELLKDKKVVVVSPIVGNSAVSGPA
HHHHHHHHHCCCCEEEECCCCCCCHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
GKLMKAKGYDVSVKGIYEFYKDIVDVLVIDNVDKEIAKEIPCEVLITNTIMKTLDDKVRL
CCCEECCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEHHHHHHHHHHHHHHH
AKNIIEFCGSL
HHHHHHHHCCC
>Mature Secondary Structure
MIFVITVLSGGTGTPKLLQGLKRVVNNEELAVIVNTGEDTWIGDLYLSPDVDTVLYTLAD
CEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHH
LINEETWYGVKEDTFYTHEQLKNLGFDEVLRIGDKDRALKMHKTYYLKRGHKLSEVVDME
HHCCHHCCCCCCCCCHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
KVALGIKAKVIPMTDDRVETKILAKVDGKVDLLKFHDFWVKRKGDVEVLDVIYENSLYAK
HHHHCCEEEEEECCCCCHHHEEEEEECCCEEEEEEHHHHHCCCCCHHEEEEHHCCCCCCC
PCEKAVEAIKNSDLVIIGPSNPITSIGPILSLNGIKELLKDKKVVVVSPIVGNSAVSGPA
HHHHHHHHHCCCCEEEECCCCCCCHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
GKLMKAKGYDVSVKGIYEFYKDIVDVLVIDNVDKEIAKEIPCEVLITNTIMKTLDDKVRL
CCCEECCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEHHHHHHHHHHHHHHH
AKNIIEFCGSL
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087