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The map label for this gene is wtpA

Identifier: 15669375

GI number: 15669375

Start: 1125191

End: 1126231

Strand: Direct

Name: wtpA

Synonym: MJ1186

Alternate gene names: 15669375

Gene position: 1125191-1126231 (Clockwise)

Preceding gene: 15669373

Following gene: 15669377

Centisome position: 67.58

GC content: 33.24

Gene sequence:

>1041_bases
ATGATAAAAAGATTAATAGTCATCTCAATATTGCTAATAGTTGGAACAGTCCTATGTGGTTGTATGGAACAGGAAAATGT
CGGACAGCAAAACTCTGAAGCCCAGGAAAAGATTGTTTTAAAGATATTCCACGCTGGAAGTTTATCTGTGCCTTTTGAAG
AGTATGAAAAGATGTTTGAAAAAGAACATCCAAATGTTGATGTTGAAAGAGAACCAGCTGGAAGTGTTGCATGTGTAAGA
AAGATAATTGACTTAGGAAAAAAGGCAGATATCTTAGCTTCAGCTGATTATTCTTTAATCCCTCAAATGATGATGCCTAA
GTATGCAGATTGGTATGTTATGTTTGCAAGAAATGAGATTGTTTTGGCTTATACAGATAAAAGTAAATATAAAGACGAAA
TAAACTCAACCAATTGGTATAAGATTTTACAGAGACCAGATGTTAAAATTGGATTCTCAAACCCTAACGATGACCCGTGT
GGTTACAGAACCCAAATGGTCCTGCAGTTAGCAGAACTCTATTATAAAGACCCAACAATCTATGACAACTTAGTTTTAAA
GCATTCAAACATAAAAGTTGAAGAAAATAACGGAACATACTTGATATTAGTCCCTAAAGAGTTAGATGTAGATACTAACA
AATTGTTTGTTAGAAGTAAGGAGACAGATTTATTAGCTCCATTAGAAGCTGGAGCGTTTGATTACCTCTTTATCTACAAG
AGTGTTGCAAACCAACACCACTTAAAATATATAGAACTTCCAAAGGAAATTAATTTAGGATATTACGAATATGCAGACAC
TTACAAAAAAGTGGCTTTAAAAATAATTGCAAAGAATAAAACAATAAATGCAAAACCAATTGTTTATGGTATGACAGTTC
CAACAAATGCACCACATAAAAAAGAAGCCATAGAGTTTGTTAAATTTGTGTTAGGGCATCCAGAAGTTTTAGAGAACAAT
GGACAGCCAGCAATAATTCCAGCAGTTGCTTATGGAAATGTTCCAGAAGAGTTAAAGGATTTGGTTAAAATAGAGAAATA
A

Upstream 100 bases:

>100_bases
ATTTTATAGATTTTGTTAATCACTATTGATGAATATAATATTTAAATATGAAATCAATTATCTTTACTTTTTGAAAATCT
ATTAAAAAAGGTGAATATAG

Downstream 100 bases:

>100_bases
TTAAATAATACTCTCTAAAAATTCAATATCCTTTATTACCTCTTCTATTTTTTCCTCTTTTGTTACCGGATTTTTTTCTA
ATCTTCTATCATCAAGCTCT

Product: molybdate ABC transporter periplasmic substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MIKRLIVISILLIVGTVLCGCMEQENVGQQNSEAQEKIVLKIFHAGSLSVPFEEYEKMFEKEHPNVDVEREPAGSVACVR
KIIDLGKKADILASADYSLIPQMMMPKYADWYVMFARNEIVLAYTDKSKYKDEINSTNWYKILQRPDVKIGFSNPNDDPC
GYRTQMVLQLAELYYKDPTIYDNLVLKHSNIKVEENNGTYLILVPKELDVDTNKLFVRSKETDLLAPLEAGAFDYLFIYK
SVANQHHLKYIELPKEINLGYYEYADTYKKVALKIIAKNKTINAKPIVYGMTVPTNAPHKKEAIEFVKFVLGHPEVLENN
GQPAIIPAVAYGNVPEELKDLVKIEK

Sequences:

>Translated_346_residues
MIKRLIVISILLIVGTVLCGCMEQENVGQQNSEAQEKIVLKIFHAGSLSVPFEEYEKMFEKEHPNVDVEREPAGSVACVR
KIIDLGKKADILASADYSLIPQMMMPKYADWYVMFARNEIVLAYTDKSKYKDEINSTNWYKILQRPDVKIGFSNPNDDPC
GYRTQMVLQLAELYYKDPTIYDNLVLKHSNIKVEENNGTYLILVPKELDVDTNKLFVRSKETDLLAPLEAGAFDYLFIYK
SVANQHHLKYIELPKEINLGYYEYADTYKKVALKIIAKNKTINAKPIVYGMTVPTNAPHKKEAIEFVKFVLGHPEVLENN
GQPAIIPAVAYGNVPEELKDLVKIEK
>Mature_346_residues
MIKRLIVISILLIVGTVLCGCMEQENVGQQNSEAQEKIVLKIFHAGSLSVPFEEYEKMFEKEHPNVDVEREPAGSVACVR
KIIDLGKKADILASADYSLIPQMMMPKYADWYVMFARNEIVLAYTDKSKYKDEINSTNWYKILQRPDVKIGFSNPNDDPC
GYRTQMVLQLAELYYKDPTIYDNLVLKHSNIKVEENNGTYLILVPKELDVDTNKLFVRSKETDLLAPLEAGAFDYLFIYK
SVANQHHLKYIELPKEINLGYYEYADTYKKVALKIIAKNKTINAKPIVYGMTVPTNAPHKKEAIEFVKFVLGHPEVLENN
GQPAIIPAVAYGNVPEELKDLVKIEK

Specific function: Part of the ABC transporter complex wtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate

COG id: COG0725

COG function: function code P; ABC-type molybdate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WTPA_METJA (Q58586)

Other databases:

- EMBL:   L77117
- PIR:   A64448
- RefSeq:   NP_248180.1
- PDB:   3CFZ
- PDBsum:   3CFZ
- ProteinModelPortal:   Q58586
- SMR:   Q58586
- GeneID:   1452084
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1186
- NMPDR:   fig|243232.1.peg.1217
- TIGR:   MJ1186
- HOGENOM:   HBG457285
- OMA:   IYKSVAN
- ProtClustDB:   PRK04168
- BioCyc:   MJAN243232:MJ_1186-MONOMER
- InterPro:   IPR022498
- InterPro:   IPR006059
- TIGRFAMs:   TIGR03730

Pfam domain/function: PF01547 SBP_bac_1

EC number: NA

Molecular weight: Translated: 39445; Mature: 39445

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRLIVISILLIVGTVLCGCMEQENVGQQNSEAQEKIVLKIFHAGSLSVPFEEYEKMFE
CCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHEEEEEEEECCCCCCCHHHHHHHHH
KEHPNVDVEREPAGSVACVRKIIDLGKKADILASADYSLIPQMMMPKYADWYVMFARNEI
HCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCCEEEEEECCEE
VLAYTDKSKYKDEINSTNWYKILQRPDVKIGFSNPNDDPCGYRTQMVLQLAELYYKDPTI
EEEEECCHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCC
YDNLVLKHSNIKVEENNGTYLILVPKELDVDTNKLFVRSKETDLLAPLEAGAFDYLFIYK
CCCEEEEECCEEEECCCCEEEEEECCCCCCCCCEEEEEECCCCEECCCCCCCHHHHHHHH
SVANQHHLKYIELPKEINLGYYEYADTYKKVALKIIAKNKTINAKPIVYGMTVPTNAPHK
HHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCCCH
KEAIEFVKFVLGHPEVLENNGQPAIIPAVAYGNVPEELKDLVKIEK
HHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MIKRLIVISILLIVGTVLCGCMEQENVGQQNSEAQEKIVLKIFHAGSLSVPFEEYEKMFE
CCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHEEEEEEEECCCCCCCHHHHHHHHH
KEHPNVDVEREPAGSVACVRKIIDLGKKADILASADYSLIPQMMMPKYADWYVMFARNEI
HCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCCEEEEEECCEE
VLAYTDKSKYKDEINSTNWYKILQRPDVKIGFSNPNDDPCGYRTQMVLQLAELYYKDPTI
EEEEECCHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCC
YDNLVLKHSNIKVEENNGTYLILVPKELDVDTNKLFVRSKETDLLAPLEAGAFDYLFIYK
CCCEEEEECCEEEECCCCEEEEEECCCCCCCCCEEEEEECCCCEECCCCCCCHHHHHHHH
SVANQHHLKYIELPKEINLGYYEYADTYKKVALKIIAKNKTINAKPIVYGMTVPTNAPHK
HHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCCCH
KEAIEFVKFVLGHPEVLENNGQPAIIPAVAYGNVPEELKDLVKIEK
HHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087