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The map label for this gene is rpa

Identifier: 15669348

GI number: 15669348

Start: 1098673

End: 1100610

Strand: Direct

Name: rpa

Synonym: MJ1159

Alternate gene names: 15669348

Gene position: 1098673-1100610 (Clockwise)

Preceding gene: 15669347

Following gene: 15669349

Centisome position: 65.99

GC content: 31.68

Gene sequence:

>1938_bases
ATGATAGGAGATTATGAAAGATTTAAACAACTCAAAAAAAAGGTTGCTGAAGCATTGAATATTAGTGAGGAGGAATTAGA
TAGGATGATTGATAAAAAAATTGAAGAAAACGGAGGAATAATATTGAAAGATGCTGCATTAATGATGATTGCAAAAGAAC
ATGGAGTTTATGGAGAAGAAAAAAATGATGAAGAATTTTTAATTAGTGATATTGAAGAGGGACAGATAGGCGTTGAGATA
ACTGGAGTTATAACTGATATCTCTGAAATAAAAACATTCAAAAGGAGAGATGGGAGTTTAGGGAAATACAAAAGAATTAC
AATAGCGGATAAGTCAGGAACTATAAGAATGACTTTATGGGACGATTTGGCTGAATTAGATGTAAAAGTTGGAGATGTTA
TTAAAATTGAAAGAGCAAGAGCAAGAAAATGGAGAAATAATTTAGAGTTGAGTTCAACATCTGAAACTAAGATTAAAAAA
TTAGAAAACTATGAAGGAGAACTTCCAGAGATTAAAGATACCTACAATATTGGTGAGCTAAGTCCTGGAATGACAGCAAC
ATTTGAAGGAGAAGTTATCTCAGCTCTTCCAATCAAAGAATTTAAAAGAGCTGATGGTAGTATTGGAAAATTAAAATCAT
TTATTGTTAGAGATGAGACAGGAAGTATAAGAGTTACCTTATGGGATAATCTAACAGATATCGATGTTGGTAGAGGAGAT
TACGTTAGAGTTAGGGGCTATATAAGGGAAGGTTATTATGGGGGTTTAGAATGCACCGCAAATTATGTAGAGATATTAAA
AAAAGGAGAAAAAATAGAGAGTGAAGAAGTAAATATTGAGGATTTAACAAAATATGAAGATGGAGAACTGGTGAGTGTTA
AAGGTAGAGTTATAGCCATAAGTAATAAAAAAAGCGTAGATTTGGATGGAGAGATAGCAAAGGTTCAAGATATTATATTA
GATAACGGCACTGGTAGAGTTAGAGTTTCATTTTGGAGAGGAAAAACTGCTTTATTGGAAAATATAAAAGAAGGGGACTT
AGTTAGAATAACAAACTGTAGAGTTAAGACGTTTTATGATAGAGAAGGAAATAAAAGAACTGATTTAGTTGCCACATTAG
AAACAGAAGTTATTAAAGATGAAAACATTGAAGCTCCAGAGTATGAGCTAAAATATTGCAAAATTGAAGATATTTATAAT
AGAGATGTTGACTGGAACGATATAAATTTAATAGCTCAAGTTGTTGAGGATTATGGAGTTAATGAAATTGAATTTGAAGA
TAAGGTTAGAAAAGTAAGAAATTTATTGTTAGAAGATGGAACTGGAAGAATAAGGTTGAGTTTATGGGATGATTTGGCTG
AAATAGAGATTAAAGAAGGAGATATTGTAGAAATTTTACATGCCTATGCTAAGGAGAGGGGAGATTATATAGATTTGGTT
ATTGGAAAATATGGAAGAATAATTATAAATCCAGAAGGGGTTGAAATAAAAACCAATAGAAAGTTTATAGCAGATATTGA
AGACGGAGAAACTGTTGAAGTTAGAGGGGCTGTAGTTAAGATATTGAGTGACACTCTCTTTCTTTATTTATGCCCAAATT
GTAGAAAGAGGGTTGTAGAGATTGATGGAATTTATAACTGCCCTATTTGTGGAGATGTTGAGCCAGAAGAGATTTTAAGA
TTGAATTTTGTTGTAGATGATGGGACTGGAACTTTATTATGTAGGGCTTATGATAGAAGAGTTGAGAAGATGTTAAAAAT
GAATAGGGAGGAGTTAAAGAACCTAACTATAGAAATGGTGGAAGATGAAATATTAGGGGAAGAGTTTGTTTTGTATGGAA
ATGTTAGAGTAGAGAATGATGAATTAATTATGGTTGTTAGAAGAGTTAATGATGTAGATGTTGAGAAAGAAATAAGAATA
TTGGAGGAAATGGAATAA

Upstream 100 bases:

>100_bases
TCCATGTAGTGGAAATATTTGCAAGGTATGTTCATGGCTCATAAAATTGAAGGAAATTAAATAGAATTCTATTCAAAATA
ATTTTTTATGGTGATGATTT

Downstream 100 bases:

>100_bases
CAAAAAATAAATAAATATAAGTCAATATTATAACCAAAAAAATTTACGGTGATGAGATGATTGTTGAGAGAGTTGAAGAG
TATTTGGACAGAATAGAAAA

Product: replication factor A

Products: NA

Alternate protein names: RF-A; RP-A; Replication factor A protein 1; Single-stranded DNA-binding protein; mjaSSB

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MIGDYERFKQLKKKVAEALNISEEELDRMIDKKIEENGGIILKDAALMMIAKEHGVYGEEKNDEEFLISDIEEGQIGVEI
TGVITDISEIKTFKRRDGSLGKYKRITIADKSGTIRMTLWDDLAELDVKVGDVIKIERARARKWRNNLELSSTSETKIKK
LENYEGELPEIKDTYNIGELSPGMTATFEGEVISALPIKEFKRADGSIGKLKSFIVRDETGSIRVTLWDNLTDIDVGRGD
YVRVRGYIREGYYGGLECTANYVEILKKGEKIESEEVNIEDLTKYEDGELVSVKGRVIAISNKKSVDLDGEIAKVQDIIL
DNGTGRVRVSFWRGKTALLENIKEGDLVRITNCRVKTFYDREGNKRTDLVATLETEVIKDENIEAPEYELKYCKIEDIYN
RDVDWNDINLIAQVVEDYGVNEIEFEDKVRKVRNLLLEDGTGRIRLSLWDDLAEIEIKEGDIVEILHAYAKERGDYIDLV
IGKYGRIIINPEGVEIKTNRKFIADIEDGETVEVRGAVVKILSDTLFLYLCPNCRKRVVEIDGIYNCPICGDVEPEEILR
LNFVVDDGTGTLLCRAYDRRVEKMLKMNREELKNLTIEMVEDEILGEEFVLYGNVRVENDELIMVVRRVNDVDVEKEIRI
LEEME

Sequences:

>Translated_645_residues
MIGDYERFKQLKKKVAEALNISEEELDRMIDKKIEENGGIILKDAALMMIAKEHGVYGEEKNDEEFLISDIEEGQIGVEI
TGVITDISEIKTFKRRDGSLGKYKRITIADKSGTIRMTLWDDLAELDVKVGDVIKIERARARKWRNNLELSSTSETKIKK
LENYEGELPEIKDTYNIGELSPGMTATFEGEVISALPIKEFKRADGSIGKLKSFIVRDETGSIRVTLWDNLTDIDVGRGD
YVRVRGYIREGYYGGLECTANYVEILKKGEKIESEEVNIEDLTKYEDGELVSVKGRVIAISNKKSVDLDGEIAKVQDIIL
DNGTGRVRVSFWRGKTALLENIKEGDLVRITNCRVKTFYDREGNKRTDLVATLETEVIKDENIEAPEYELKYCKIEDIYN
RDVDWNDINLIAQVVEDYGVNEIEFEDKVRKVRNLLLEDGTGRIRLSLWDDLAEIEIKEGDIVEILHAYAKERGDYIDLV
IGKYGRIIINPEGVEIKTNRKFIADIEDGETVEVRGAVVKILSDTLFLYLCPNCRKRVVEIDGIYNCPICGDVEPEEILR
LNFVVDDGTGTLLCRAYDRRVEKMLKMNREELKNLTIEMVEDEILGEEFVLYGNVRVENDELIMVVRRVNDVDVEKEIRI
LEEME
>Mature_645_residues
MIGDYERFKQLKKKVAEALNISEEELDRMIDKKIEENGGIILKDAALMMIAKEHGVYGEEKNDEEFLISDIEEGQIGVEI
TGVITDISEIKTFKRRDGSLGKYKRITIADKSGTIRMTLWDDLAELDVKVGDVIKIERARARKWRNNLELSSTSETKIKK
LENYEGELPEIKDTYNIGELSPGMTATFEGEVISALPIKEFKRADGSIGKLKSFIVRDETGSIRVTLWDNLTDIDVGRGD
YVRVRGYIREGYYGGLECTANYVEILKKGEKIESEEVNIEDLTKYEDGELVSVKGRVIAISNKKSVDLDGEIAKVQDIIL
DNGTGRVRVSFWRGKTALLENIKEGDLVRITNCRVKTFYDREGNKRTDLVATLETEVIKDENIEAPEYELKYCKIEDIYN
RDVDWNDINLIAQVVEDYGVNEIEFEDKVRKVRNLLLEDGTGRIRLSLWDDLAEIEIKEGDIVEILHAYAKERGDYIDLV
IGKYGRIIINPEGVEIKTNRKFIADIEDGETVEVRGAVVKILSDTLFLYLCPNCRKRVVEIDGIYNCPICGDVEPEEILR
LNFVVDDGTGTLLCRAYDRRVEKMLKMNREELKNLTIEMVEDEILGEEFVLYGNVRVENDELIMVVRRVNDVDVEKEIRI
LEEME

Specific function: Probably plays an essential for replication of the chromosome, DNA recombination and repair

COG id: COG1599

COG function: function code L; Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 OB DNA-binding domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPA_METJA (Q58559)

Other databases:

- EMBL:   L77117
- PIR:   F64444
- RefSeq:   NP_248153.1
- PDB:   3DM3
- PDBsum:   3DM3
- ProteinModelPortal:   Q58559
- SMR:   Q58559
- GeneID:   1452057
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1159
- NMPDR:   fig|243232.1.peg.1190
- TIGR:   MJ1159
- HOGENOM:   HBG541102
- OMA:   WNELADF
- ProtClustDB:   PRK12366
- BioCyc:   MJAN243232:MJ_1159-MONOMER
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR013955
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF08646 Rep_fac-A_C; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 73843; Mature: 73843

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGDYERFKQLKKKVAEALNISEEELDRMIDKKIEENGGIILKDAALMMIAKEHGVYGEE
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCEEEEEEHHCCCCCCC
KNDEEFLISDIEEGQIGVEITGVITDISEIKTFKRRDGSLGKYKRITIADKSGTIRMTLW
CCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEC
DDLAELDVKVGDVIKIERARARKWRNNLELSSTSETKIKKLENYEGELPEIKDTYNIGEL
CCHHHCCCCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
SPGMTATFEGEVISALPIKEFKRADGSIGKLKSFIVRDETGSIRVTLWDNLTDIDVGRGD
CCCCEEEECCCEEEECCHHHHHHCCCCHHHHHHEEEECCCCCEEEEEECCCEEEECCCCC
YVRVRGYIREGYYGGLECTANYVEILKKGEKIESEEVNIEDLTKYEDGELVSVKGRVIAI
EEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEEECCEEEEE
SNKKSVDLDGEIAKVQDIILDNGTGRVRVSFWRGKTALLENIKEGDLVRITNCRVKTFYD
ECCCCCCCCCCHHHEEEEEEECCCCEEEEEEECCCHHHHHCCCCCCEEEEECEEEEEEEC
REGNKRTDLVATLETEVIKDENIEAPEYELKYCKIEDIYNRDVDWNDINLIAQVVEDYGV
CCCCCCCEEEEEEEHHHHCCCCCCCCCCEEEEEEEEHHHCCCCCCCHHHHHHHHHHHCCC
NEIEFEDKVRKVRNLLLEDGTGRIRLSLWDDLAEIEIKEGDIVEILHAYAKERGDYIDLV
CEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHCCCCEEEEE
IGKYGRIIINPEGVEIKTNRKFIADIEDGETVEVRGAVVKILSDTLFLYLCPNCRKRVVE
ECCCCEEEECCCCEEEEECCEEEEECCCCCEEEEHHHHHHHHHHCEEEEECCCHHCEEEE
IDGIYNCPICGDVEPEEILRLNFVVDDGTGTLLCRAYDRRVEKMLKMNREELKNLTIEMV
ECCEEECCCCCCCCHHHEEEEEEEEECCCCEEEEEHHHHHHHHHHHCCHHHHHCCCHHHH
EDEILGEEFVLYGNVRVENDELIMVVRRVNDVDVEKEIRILEEME
HHHHCCCEEEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MIGDYERFKQLKKKVAEALNISEEELDRMIDKKIEENGGIILKDAALMMIAKEHGVYGEE
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCEEEEEEHHCCCCCCC
KNDEEFLISDIEEGQIGVEITGVITDISEIKTFKRRDGSLGKYKRITIADKSGTIRMTLW
CCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEC
DDLAELDVKVGDVIKIERARARKWRNNLELSSTSETKIKKLENYEGELPEIKDTYNIGEL
CCHHHCCCCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
SPGMTATFEGEVISALPIKEFKRADGSIGKLKSFIVRDETGSIRVTLWDNLTDIDVGRGD
CCCCEEEECCCEEEECCHHHHHHCCCCHHHHHHEEEECCCCCEEEEEECCCEEEECCCCC
YVRVRGYIREGYYGGLECTANYVEILKKGEKIESEEVNIEDLTKYEDGELVSVKGRVIAI
EEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEEECCEEEEE
SNKKSVDLDGEIAKVQDIILDNGTGRVRVSFWRGKTALLENIKEGDLVRITNCRVKTFYD
ECCCCCCCCCCHHHEEEEEEECCCCEEEEEEECCCHHHHHCCCCCCEEEEECEEEEEEEC
REGNKRTDLVATLETEVIKDENIEAPEYELKYCKIEDIYNRDVDWNDINLIAQVVEDYGV
CCCCCCCEEEEEEEHHHHCCCCCCCCCCEEEEEEEEHHHCCCCCCCHHHHHHHHHHHCCC
NEIEFEDKVRKVRNLLLEDGTGRIRLSLWDDLAEIEIKEGDIVEILHAYAKERGDYIDLV
CEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHCCCCEEEEE
IGKYGRIIINPEGVEIKTNRKFIADIEDGETVEVRGAVVKILSDTLFLYLCPNCRKRVVE
ECCCCEEEECCCCEEEEECCEEEEECCCCCEEEEHHHHHHHHHHCEEEEECCCHHCEEEE
IDGIYNCPICGDVEPEEILRLNFVVDDGTGTLLCRAYDRRVEKMLKMNREELKNLTIEMV
ECCEEECCCCCCCCHHHEEEEEEEEECCCCEEEEEHHHHHHHHHHHCCHHHHHCCCHHHH
EDEILGEEFVLYGNVRVENDELIMVVRRVNDVDVEKEIRILEEME
HHHHCCCEEEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9843941