Click here to switch to the map view.

The map label for this gene is 15669154

Identifier: 15669154

GI number: 15669154

Start: 897012

End: 899054

Strand: Reverse

Name: 15669154

Synonym: MJ0964

Alternate gene names: NA

Gene position: 899054-897012 (Counterclockwise)

Preceding gene: 15669157

Following gene: 15669153

Centisome position: 54.0

GC content: 35.93

Gene sequence:

>2043_bases
ATGGTTATGGGATACAGAGTAGGAATTGATATAGGTGGGACATTTACAGACCTCGTTTATTTTGATGAATATAGCAAAGA
ATTTCATGTAGTTAAAGTTCCAACAACTCCAAAGAGTCCTGATGTTGGGGCAATAAATGCAATAGAAACTGCTAAAATAG
AATTTGATAAGATAAATATTTTAATCCACGCAACCACCTTAGGAACAAACATGTTTTTAGGGCAAGAGCACTTAAACCCA
CCAAAAATTGCACTAATTACAACAAAGGGATTTAAGGATGTTATTGAAATTGGTAGGCAGAGGAGGCCTAAACTTTATGA
TTTATTCTTTGAAAAGCCAAAGCCATTAATAAAGAGGAGAGACAGATATGAGGTTGAAGAGAGGATAGATGCAAATGGAA
ATATAATCACTCCACTAAATGAGGAGGAATTGCAAAAAATAGCTGAAATTATTAAGAAAAAGGATTATGAAGTTGTTGTT
ATCTCTTTTTTACACAGCTATAAGAATCCAATCCATGAAAAGAAGGCAAGGGAAATAATAAAAAATCTCTGCTCTAATGT
GGATGTTATAACCTCCTACGAAATAAATCCAGAGTATAAGGAGTATGAGAGAACAAGCACAACCGTTATTAACGCCTATC
TAAAGCCATTAGTGTCCAATTATCTAAAAAACTTCATAGATTCTTTAAAAAACAAAGGCTTTAATGGAAAGTTTTATGTT
ATGCAGAGTAGTGGAGGCATCTCAAATATAAAATATGCCACTGAAAGACCTGCAGCATTTATAGAATCCGGTCCAGCCGC
TGGAGCTATTGCAGTCGCCTATTTTTCAAAAATTTTAAATGATAACAAAGTTATAGGCTTTGATATGGGTGGAACAACTG
CTAAGGCATCAACTATAATTAACAACTCTCCATTGGTAACAAATGAGTATGAGGTTGGAGGAGAGGTTCATGCTGGAAGA
TTAATTAAAGGCTCTGGTTATCCTGTTAGATTTCCATTTATTGATTTGGCTGAGGTTAGTGCTGGAGGAGGGACAATAGC
ATGGGTTGATGAAGGAAATGCCTTAAGAGTTGGGCCGATAAGTGCTGGAGCTGACCCGGGGCCTGTTTGCTATGGAAAGG
GAAATGATAAACCAACAATAACTGATGCCAACTTAATCCTTGGTAGATTGGGAGAGAAGCTTAGTGGTGGTCTATTAAAA
TTAAGAAAAGATTTAGCTGAAAAGGCAATATCAAAATTAGCTGAAAAAATAGGGGAGAGTGTTGAAGAAATCGCCTATGG
AATAATAAGATTGGCAAACACCACCATGGCAAAGGCTTTAAGAATAGTTACAGTTGAGAGAGGCTATGACCCAAGGGATT
TTGTCATGTATGTTTTTGGTGGAGCTGGACCTTTACATGGAGTTGAGTTGGCAGAGGAGATGGAGATTAGCTCTATATTA
ATTCCTCCTTCGTGTGGTGTTTTCTCTGCTTTAGGGCTTTTATTGGCTGATTGTAGGGTAGATAAAGCTAAGAGTATATT
GAAAGATATAGATGAAGTTGATGAGGAAGAGATTGAGAATATATTTATTGAGCTAATAGAGGAGGGACTTAAAGAGGTTG
AGGGCTTTGAGGAGATAAAGATAGTTAAACAGATTGATGTTAGATATAAAGGGCAATCTTATGAACTAACAATCCCTTGG
ACTGGAGATTTAAAAGAATTGGCAGATAACTTCCACAAAAAGCATGAGACTGTTTATAAATTCAGTTCTTTAGAGGAAGA
TATTGAGTTGGTTAATGCAAGGGTTACAATTATTGGTTTATTAACAAAGCCAGAGATAAAATGTTATGAAGTTAAAGAAT
ACAAACCAAAGCCAGAGAGTTATAGAAAGGTTTATTTCAGCAGTGGATGGGAAGAGACTGCAATTTATAATAGGGATAAG
CTTAAACCAGGAGCTATATTTGAAGGACCGGCAGTAGTTGAAGAGTATGATTCAACTATCGTAATTCCTCCAGATTATAC
AGCTTTTGTTGATAAATACGGATGTTTAAGAATTGAGAGATAA

Upstream 100 bases:

>100_bases
GCTCCTACTAAGATAACTTTGCCTGTCATTATTTCACCAGAAATGTTTATATTTTTTGGCATTAAAATAAGTTATAGCTT
CTAATACTAATTTTTATGGG

Downstream 100 bases:

>100_bases
AAGGGGATTGTTATGGATAAAATTACAGTTGAGGTTATTAAAAGCTCTACCTCATATATTGCAGAAGAGATGGGAATTAT
TTTGAGAAATACAGCCTATT

Product: hydantoin utilization protein HyuA

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MVMGYRVGIDIGGTFTDLVYFDEYSKEFHVVKVPTTPKSPDVGAINAIETAKIEFDKINILIHATTLGTNMFLGQEHLNP
PKIALITTKGFKDVIEIGRQRRPKLYDLFFEKPKPLIKRRDRYEVEERIDANGNIITPLNEEELQKIAEIIKKKDYEVVV
ISFLHSYKNPIHEKKAREIIKNLCSNVDVITSYEINPEYKEYERTSTTVINAYLKPLVSNYLKNFIDSLKNKGFNGKFYV
MQSSGGISNIKYATERPAAFIESGPAAGAIAVAYFSKILNDNKVIGFDMGGTTAKASTIINNSPLVTNEYEVGGEVHAGR
LIKGSGYPVRFPFIDLAEVSAGGGTIAWVDEGNALRVGPISAGADPGPVCYGKGNDKPTITDANLILGRLGEKLSGGLLK
LRKDLAEKAISKLAEKIGESVEEIAYGIIRLANTTMAKALRIVTVERGYDPRDFVMYVFGGAGPLHGVELAEEMEISSIL
IPPSCGVFSALGLLLADCRVDKAKSILKDIDEVDEEEIENIFIELIEEGLKEVEGFEEIKIVKQIDVRYKGQSYELTIPW
TGDLKELADNFHKKHETVYKFSSLEEDIELVNARVTIIGLLTKPEIKCYEVKEYKPKPESYRKVYFSSGWEETAIYNRDK
LKPGAIFEGPAVVEEYDSTIVIPPDYTAFVDKYGCLRIER

Sequences:

>Translated_680_residues
MVMGYRVGIDIGGTFTDLVYFDEYSKEFHVVKVPTTPKSPDVGAINAIETAKIEFDKINILIHATTLGTNMFLGQEHLNP
PKIALITTKGFKDVIEIGRQRRPKLYDLFFEKPKPLIKRRDRYEVEERIDANGNIITPLNEEELQKIAEIIKKKDYEVVV
ISFLHSYKNPIHEKKAREIIKNLCSNVDVITSYEINPEYKEYERTSTTVINAYLKPLVSNYLKNFIDSLKNKGFNGKFYV
MQSSGGISNIKYATERPAAFIESGPAAGAIAVAYFSKILNDNKVIGFDMGGTTAKASTIINNSPLVTNEYEVGGEVHAGR
LIKGSGYPVRFPFIDLAEVSAGGGTIAWVDEGNALRVGPISAGADPGPVCYGKGNDKPTITDANLILGRLGEKLSGGLLK
LRKDLAEKAISKLAEKIGESVEEIAYGIIRLANTTMAKALRIVTVERGYDPRDFVMYVFGGAGPLHGVELAEEMEISSIL
IPPSCGVFSALGLLLADCRVDKAKSILKDIDEVDEEEIENIFIELIEEGLKEVEGFEEIKIVKQIDVRYKGQSYELTIPW
TGDLKELADNFHKKHETVYKFSSLEEDIELVNARVTIIGLLTKPEIKCYEVKEYKPKPESYRKVYFSSGWEETAIYNRDK
LKPGAIFEGPAVVEEYDSTIVIPPDYTAFVDKYGCLRIER
>Mature_680_residues
MVMGYRVGIDIGGTFTDLVYFDEYSKEFHVVKVPTTPKSPDVGAINAIETAKIEFDKINILIHATTLGTNMFLGQEHLNP
PKIALITTKGFKDVIEIGRQRRPKLYDLFFEKPKPLIKRRDRYEVEERIDANGNIITPLNEEELQKIAEIIKKKDYEVVV
ISFLHSYKNPIHEKKAREIIKNLCSNVDVITSYEINPEYKEYERTSTTVINAYLKPLVSNYLKNFIDSLKNKGFNGKFYV
MQSSGGISNIKYATERPAAFIESGPAAGAIAVAYFSKILNDNKVIGFDMGGTTAKASTIINNSPLVTNEYEVGGEVHAGR
LIKGSGYPVRFPFIDLAEVSAGGGTIAWVDEGNALRVGPISAGADPGPVCYGKGNDKPTITDANLILGRLGEKLSGGLLK
LRKDLAEKAISKLAEKIGESVEEIAYGIIRLANTTMAKALRIVTVERGYDPRDFVMYVFGGAGPLHGVELAEEMEISSIL
IPPSCGVFSALGLLLADCRVDKAKSILKDIDEVDEEEIENIFIELIEEGLKEVEGFEEIKIVKQIDVRYKGQSYELTIPW
TGDLKELADNFHKKHETVYKFSSLEEDIELVNARVTIIGLLTKPEIKCYEVKEYKPKPESYRKVYFSSGWEETAIYNRDK
LKPGAIFEGPAVVEEYDSTIVIPPDYTAFVDKYGCLRIER

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family

Homologues:

Organism=Homo sapiens, GI48314820, Length=755, Percent_Identity=26.2251655629139, Blast_Score=188, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI133901900, Length=740, Percent_Identity=26.6216216216216, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6322634, Length=747, Percent_Identity=29.4511378848728, Blast_Score=222, Evalue=1e-58,
Organism=Drosophila melanogaster, GI45550492, Length=749, Percent_Identity=28.3044058744993, Blast_Score=225, Evalue=7e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y964_METJA (Q58374)

Other databases:

- EMBL:   L77117
- PIR:   D64420
- RefSeq:   NP_247959.1
- ProteinModelPortal:   Q58374
- GeneID:   1451862
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0964
- NMPDR:   fig|243232.1.peg.996
- TIGR:   MJ0964
- HOGENOM:   HBG658426
- OMA:   IKGSGYP
- ProtClustDB:   CLSK696678
- BioCyc:   MJAN243232:MJ_0964-MONOMER
- InterPro:   IPR008040
- InterPro:   IPR002821

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A

EC number: 3.5.2.14

Molecular weight: Translated: 75844; Mature: 75844

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMGYRVGIDIGGTFTDLVYFDEYSKEFHVVKVPTTPKSPDVGAINAIETAKIEFDKINI
CEEEEEEEEECCCCHHHEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEE
LIHATTLGTNMFLGQEHLNPPKIALITTKGFKDVIEIGRQRRPKLYDLFFEKPKPLIKRR
EEEEEEECCEEEECCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHCCCCHHHHCC
DRYEVEERIDANGNIITPLNEEELQKIAEIIKKKDYEVVVISFLHSYKNPIHEKKAREII
CCCCHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHHHHHHH
KNLCSNVDVITSYEINPEYKEYERTSTTVINAYLKPLVSNYLKNFIDSLKNKGFNGKFYV
HHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
MQSSGGISNIKYATERPAAFIESGPAAGAIAVAYFSKILNDNKVIGFDMGGTTAKASTII
EECCCCCCCCEECCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHEEE
NNSPLVTNEYEVGGEVHAGRLIKGSGYPVRFPFIDLAEVSAGGGTIAWVDEGNALRVGPI
CCCCCEECCCCCCCEEECCEEEECCCCEEECCCEEHEEECCCCCEEEEEECCCEEEEECC
SAGADPGPVCYGKGNDKPTITDANLILGRLGEKLSGGLLKLRKDLAEKAISKLAEKIGES
CCCCCCCCEEECCCCCCCCEEHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VEEIAYGIIRLANTTMAKALRIVTVERGYDPRDFVMYVFGGAGPLHGVELAEEMEISSIL
HHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEE
IPPSCGVFSALGLLLADCRVDKAKSILKDIDEVDEEEIENIFIELIEEGLKEVEGFEEIK
ECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHH
IVKQIDVRYKGQSYELTIPWTGDLKELADNFHKKHETVYKFSSLEEDIELVNARVTIIGL
HHHHHCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEE
LTKPEIKCYEVKEYKPKPESYRKVYFSSGWEETAIYNRDKLKPGAIFEGPAVVEEYDSTI
ECCCCCEEEEECCCCCCCHHHHEEEECCCCCHHEECCCCCCCCCCEECCCHHHHHCCCEE
VIPPDYTAFVDKYGCLRIER
EECCCHHHHHCCCCCEEECC
>Mature Secondary Structure
MVMGYRVGIDIGGTFTDLVYFDEYSKEFHVVKVPTTPKSPDVGAINAIETAKIEFDKINI
CEEEEEEEEECCCCHHHEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEE
LIHATTLGTNMFLGQEHLNPPKIALITTKGFKDVIEIGRQRRPKLYDLFFEKPKPLIKRR
EEEEEEECCEEEECCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHCCCCHHHHCC
DRYEVEERIDANGNIITPLNEEELQKIAEIIKKKDYEVVVISFLHSYKNPIHEKKAREII
CCCCHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHHHHHHH
KNLCSNVDVITSYEINPEYKEYERTSTTVINAYLKPLVSNYLKNFIDSLKNKGFNGKFYV
HHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
MQSSGGISNIKYATERPAAFIESGPAAGAIAVAYFSKILNDNKVIGFDMGGTTAKASTII
EECCCCCCCCEECCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHEEE
NNSPLVTNEYEVGGEVHAGRLIKGSGYPVRFPFIDLAEVSAGGGTIAWVDEGNALRVGPI
CCCCCEECCCCCCCEEECCEEEECCCCEEECCCEEHEEECCCCCEEEEEECCCEEEEECC
SAGADPGPVCYGKGNDKPTITDANLILGRLGEKLSGGLLKLRKDLAEKAISKLAEKIGES
CCCCCCCCEEECCCCCCCCEEHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VEEIAYGIIRLANTTMAKALRIVTVERGYDPRDFVMYVFGGAGPLHGVELAEEMEISSIL
HHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEE
IPPSCGVFSALGLLLADCRVDKAKSILKDIDEVDEEEIENIFIELIEEGLKEVEGFEEIK
ECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHH
IVKQIDVRYKGQSYELTIPWTGDLKELADNFHKKHETVYKFSSLEEDIELVNARVTIIGL
HHHHHCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEE
LTKPEIKCYEVKEYKPKPESYRKVYFSSGWEETAIYNRDKLKPGAIFEGPAVVEEYDSTI
ECCCCCEEEEECCCCCCCHHHHEEEECCCCCHHEECCCCCCCCCCEECCCHHHHHCCCEE
VIPPDYTAFVDKYGCLRIER
EECCCHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087