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The map label for this gene is 15669153

Identifier: 15669153

GI number: 15669153

Start: 895308

End: 896999

Strand: Reverse

Name: 15669153

Synonym: MJ0963

Alternate gene names: NA

Gene position: 896999-895308 (Counterclockwise)

Preceding gene: 15669154

Following gene: 15669150

Centisome position: 53.87

GC content: 34.22

Gene sequence:

>1692_bases
ATGGATAAAATTACAGTTGAGGTTATTAAAAGCTCTACCTCATATATTGCAGAAGAGATGGGAATTATTTTGAGAAATAC
AGCCTATTCTCCAAATATTAAGGACAGATTAGATTTTAGCTGTGCTATCTTATCATCAAATGGAGAGTTAATAGCCCAAG
CTGAACACATCCCAGTGCATTTAGGGAGTATGGCTATTGGAGTTAAGAATACCGTTGATTATCTAAAAAAAGAGAGCATT
GAGATTGAGAAGGACGATGTAATTATCGTTAACGACCCATACATAGCTGGAACTCATCTAAATGACATCACCCTCTTAAA
ACCAATATTTTATAACGATGAAATAATTGGCTATGTGGCAAATAAGGCTCATCATGTAGATGTTGGTGGCTATGCACCAG
GAAGTATAAGCAGTAACGTAAAAGAACTCTACCACGAAGGTTTAATTATTCCTCCCTCTAAGCTCGTTATAAATGGAAAG
TTAAACAAAGAGCTCTTAAATCTAATAACATCAAATGTTAGAGTGCCAAAATCAACAATTGGAGATTTAAAAGCTCAAAT
AGCATCATTGAACATTGGTGTTGAGAGAATTTTAAAACTAATTGAAAAGTATGGGGATAGAGAAGTTACTGAGGCATGGA
ATAAGAGTTTAGATTATTCTGAGGAATATTTAAAATCAAAAATTAGAGATATTAACTGTATATGTGAGGCAGTAGATTAC
CTTGAATATAAGGACAAATTAATAAATATAAATATGAAGATTGAGATAAAAAATGGCAAAATAAAAGTTGATTTTACTGG
AACGCATAGACAGTTAGATGCTCCATTAAATGCTGTTTATGGTGTTACCGTTGCATCAACATCCTTTGCATTAAAGGCAG
TTATAGACCCTGATTTACCAATGAATCATGGTATCTTTAGAGTTTTAAATATCATTGCTCCAGAGGAAACAATTGTTAAT
CCAAAGAAACCAGCTCCAGTTTCTGTTGGTAATGTAGAAACCTCTCAAAGAATAGTTGATGTGATATTTAAAGCCCTCTA
CCATGAATTCCCAGATAGAGTGCCAGCCGCATCAAACGGGAGTATGAACAACGTTATTATTGGGGGAAGAGGTTGGGCAT
TCTATGAAACAATTGGAGGAGGATTTGGAGGAAGAAATGGAAAAGATGGAGTTGATGGAGTTCATGCAAATATGACAAAC
ACTCTCAATACTCCAATTGAAGTTATAGAGAACGAATATCCAATAATGATTCTTGAATACTCTCTAAGAGAAGATTCTGG
AGGAGCTGGGAAGTATAGGGGAGGTTTGGGAATAAGGAGAGTTTATAAAATGCTATCTGACTGCATGCTCTCCATAATTG
CTGATAGAATTAAAATTTCCCCATGGGGAGTTAATAATGGCTATAGTGGAGCGTGTGGAGAGCATTATGTTATAAAAGAT
GGTAAAAAAATCCCATTATCTGGAAAAGATACTTTATATTTAAGTTGTGGTGATATAGTTGAAATAAACACTCCTGGTGG
TGGGGGCTACGGCTCTCCTTATGAAAGAGATATAAATCTAATATTAGAGGATGTTAAAGATGAAAAAATTTCCATAAAAT
CGGCATATAGGGATTATAAAGTAAAAATTATCAAAAAAGATGATGATTTCGTTGTTGATATGGAAGAAACAAAAAAGTTA
AGAGGTTTGTGA

Upstream 100 bases:

>100_bases
AGTTGAAGAGTATGATTCAACTATCGTAATTCCTCCAGATTATACAGCTTTTGTTGATAAATACGGATGTTTAAGAATTG
AGAGATAAAAGGGGATTGTT

Downstream 100 bases:

>100_bases
GTTTGATTTTGCTTTTAATCTTTCCTCTAATTTTTTCCTTCTCTTTTCTTTCTTCTCTCTAATCATTGGGATTCTATATA
TTGCTCCGCATTCTAAGCAT

Product: hydantoin utilization protein HyuB

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MDKITVEVIKSSTSYIAEEMGIILRNTAYSPNIKDRLDFSCAILSSNGELIAQAEHIPVHLGSMAIGVKNTVDYLKKESI
EIEKDDVIIVNDPYIAGTHLNDITLLKPIFYNDEIIGYVANKAHHVDVGGYAPGSISSNVKELYHEGLIIPPSKLVINGK
LNKELLNLITSNVRVPKSTIGDLKAQIASLNIGVERILKLIEKYGDREVTEAWNKSLDYSEEYLKSKIRDINCICEAVDY
LEYKDKLININMKIEIKNGKIKVDFTGTHRQLDAPLNAVYGVTVASTSFALKAVIDPDLPMNHGIFRVLNIIAPEETIVN
PKKPAPVSVGNVETSQRIVDVIFKALYHEFPDRVPAASNGSMNNVIIGGRGWAFYETIGGGFGGRNGKDGVDGVHANMTN
TLNTPIEVIENEYPIMILEYSLREDSGGAGKYRGGLGIRRVYKMLSDCMLSIIADRIKISPWGVNNGYSGACGEHYVIKD
GKKIPLSGKDTLYLSCGDIVEINTPGGGGYGSPYERDINLILEDVKDEKISIKSAYRDYKVKIIKKDDDFVVDMEETKKL
RGL

Sequences:

>Translated_563_residues
MDKITVEVIKSSTSYIAEEMGIILRNTAYSPNIKDRLDFSCAILSSNGELIAQAEHIPVHLGSMAIGVKNTVDYLKKESI
EIEKDDVIIVNDPYIAGTHLNDITLLKPIFYNDEIIGYVANKAHHVDVGGYAPGSISSNVKELYHEGLIIPPSKLVINGK
LNKELLNLITSNVRVPKSTIGDLKAQIASLNIGVERILKLIEKYGDREVTEAWNKSLDYSEEYLKSKIRDINCICEAVDY
LEYKDKLININMKIEIKNGKIKVDFTGTHRQLDAPLNAVYGVTVASTSFALKAVIDPDLPMNHGIFRVLNIIAPEETIVN
PKKPAPVSVGNVETSQRIVDVIFKALYHEFPDRVPAASNGSMNNVIIGGRGWAFYETIGGGFGGRNGKDGVDGVHANMTN
TLNTPIEVIENEYPIMILEYSLREDSGGAGKYRGGLGIRRVYKMLSDCMLSIIADRIKISPWGVNNGYSGACGEHYVIKD
GKKIPLSGKDTLYLSCGDIVEINTPGGGGYGSPYERDINLILEDVKDEKISIKSAYRDYKVKIIKKDDDFVVDMEETKKL
RGL
>Mature_563_residues
MDKITVEVIKSSTSYIAEEMGIILRNTAYSPNIKDRLDFSCAILSSNGELIAQAEHIPVHLGSMAIGVKNTVDYLKKESI
EIEKDDVIIVNDPYIAGTHLNDITLLKPIFYNDEIIGYVANKAHHVDVGGYAPGSISSNVKELYHEGLIIPPSKLVINGK
LNKELLNLITSNVRVPKSTIGDLKAQIASLNIGVERILKLIEKYGDREVTEAWNKSLDYSEEYLKSKIRDINCICEAVDY
LEYKDKLININMKIEIKNGKIKVDFTGTHRQLDAPLNAVYGVTVASTSFALKAVIDPDLPMNHGIFRVLNIIAPEETIVN
PKKPAPVSVGNVETSQRIVDVIFKALYHEFPDRVPAASNGSMNNVIIGGRGWAFYETIGGGFGGRNGKDGVDGVHANMTN
TLNTPIEVIENEYPIMILEYSLREDSGGAGKYRGGLGIRRVYKMLSDCMLSIIADRIKISPWGVNNGYSGACGEHYVIKD
GKKIPLSGKDTLYLSCGDIVEINTPGGGGYGSPYERDINLILEDVKDEKISIKSAYRDYKVKIIKKDDDFVVDMEETKKL
RGL

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family

Homologues:

Organism=Homo sapiens, GI48314820, Length=537, Percent_Identity=34.2644320297952, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI133901900, Length=534, Percent_Identity=36.1423220973783, Blast_Score=322, Evalue=5e-88,
Organism=Caenorhabditis elegans, GI133901902, Length=503, Percent_Identity=35.3876739562624, Blast_Score=296, Evalue=3e-80,
Organism=Saccharomyces cerevisiae, GI6322634, Length=547, Percent_Identity=35.2833638025594, Blast_Score=298, Evalue=2e-81,
Organism=Drosophila melanogaster, GI45550492, Length=535, Percent_Identity=34.7663551401869, Blast_Score=306, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y963_METJA (Q58373)

Other databases:

- EMBL:   L77117
- PIR:   C64420
- RefSeq:   NP_247958.1
- ProteinModelPortal:   Q58373
- GeneID:   1451861
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0963
- NMPDR:   fig|243232.1.peg.995
- TIGR:   MJ0963
- HOGENOM:   HBG301772
- OMA:   TPIEVIE
- ProtClustDB:   CLSK689739
- BioCyc:   MJAN243232:MJ_0963-MONOMER
- InterPro:   IPR003692

Pfam domain/function: PF02538 Hydantoinase_B

EC number: 3.5.2.14

Molecular weight: Translated: 62149; Mature: 62149

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKITVEVIKSSTSYIAEEMGIILRNTAYSPNIKDRLDFSCAILSSNGELIAQAEHIPVH
CCCEEEEEECCHHHHHHHHHCEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCEE
LGSMAIGVKNTVDYLKKESIEIEKDDVIIVNDPYIAGTHLNDITLLKPIFYNDEIIGYVA
ECCEEECHHHHHHHHHHCCCEEECCCEEEEECCEEECCCCCCEEEEEEEEECCCEEEEEE
NKAHHVDVGGYAPGSISSNVKELYHEGLIIPPSKLVINGKLNKELLNLITSNVRVPKSTI
CCCEEEECCCCCCCCCHHHHHHHHHCCEEECCCCEEEECCCCHHHHHHHHCCCCCCHHHH
GDLKAQIASLNIGVERILKLIEKYGDREVTEAWNKSLDYSEEYLKSKIRDINCICEAVDY
HHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEYKDKLININMKIEIKNGKIKVDFTGTHRQLDAPLNAVYGVTVASTSFALKAVIDPDLP
HHHCCEEEEEEEEEEEECCEEEEEECCCCCCCCCCCHHEEEEEEECCCEEEEEEECCCCC
MNHGIFRVLNIIAPEETIVNPKKPAPVSVGNVETSQRIVDVIFKALYHEFPDRVPAASNG
CCCCHHHHHHHCCCCHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
SMNNVIIGGRGWAFYETIGGGFGGRNGKDGVDGVHANMTNTLNTPIEVIENEYPIMILEY
CCCEEEECCCCEEEEHHHCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHCCCCCEEEEEE
SLREDSGGAGKYRGGLGIRRVYKMLSDCMLSIIADRIKISPWGVNNGYSGACGEHYVIKD
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEEC
GKKIPLSGKDTLYLSCGDIVEINTPGGGGYGSPYERDINLILEDVKDEKISIKSAYRDYK
CCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHCCCEE
VKIIKKDDDFVVDMEETKKLRGL
EEEEECCCCEEEEHHHHHHHCCC
>Mature Secondary Structure
MDKITVEVIKSSTSYIAEEMGIILRNTAYSPNIKDRLDFSCAILSSNGELIAQAEHIPVH
CCCEEEEEECCHHHHHHHHHCEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCEE
LGSMAIGVKNTVDYLKKESIEIEKDDVIIVNDPYIAGTHLNDITLLKPIFYNDEIIGYVA
ECCEEECHHHHHHHHHHCCCEEECCCEEEEECCEEECCCCCCEEEEEEEEECCCEEEEEE
NKAHHVDVGGYAPGSISSNVKELYHEGLIIPPSKLVINGKLNKELLNLITSNVRVPKSTI
CCCEEEECCCCCCCCCHHHHHHHHHCCEEECCCCEEEECCCCHHHHHHHHCCCCCCHHHH
GDLKAQIASLNIGVERILKLIEKYGDREVTEAWNKSLDYSEEYLKSKIRDINCICEAVDY
HHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEYKDKLININMKIEIKNGKIKVDFTGTHRQLDAPLNAVYGVTVASTSFALKAVIDPDLP
HHHCCEEEEEEEEEEEECCEEEEEECCCCCCCCCCCHHEEEEEEECCCEEEEEEECCCCC
MNHGIFRVLNIIAPEETIVNPKKPAPVSVGNVETSQRIVDVIFKALYHEFPDRVPAASNG
CCCCHHHHHHHCCCCHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
SMNNVIIGGRGWAFYETIGGGFGGRNGKDGVDGVHANMTNTLNTPIEVIENEYPIMILEY
CCCEEEECCCCEEEEHHHCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHCCCCCEEEEEE
SLREDSGGAGKYRGGLGIRRVYKMLSDCMLSIIADRIKISPWGVNNGYSGACGEHYVIKD
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEEC
GKKIPLSGKDTLYLSCGDIVEINTPGGGGYGSPYERDINLILEDVKDEKISIKSAYRDYK
CCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHCCCEE
VKIIKKDDDFVVDMEETKKLRGL
EEEEECCCCEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087