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The map label for this gene is hdrB1

Identifier: 15668924

GI number: 15668924

Start: 669935

End: 670819

Strand: Reverse

Name: hdrB1

Synonym: MJ0743

Alternate gene names: 15668924

Gene position: 670819-669935 (Counterclockwise)

Preceding gene: 15668925

Following gene: 15668923

Centisome position: 40.29

GC content: 35.59

Gene sequence:

>885_bases
ATGGAATTTGTGTTCTTTTTGGGATGTATTGCTCCAAACAGATACCCAGGCATTGAAAAAGCCACATATATAACAATGGA
GAAACTTGGAATAAAATTACACCCCTTTGAAAAGGCATCTTGCTGTCCAGCTCCAGGGGTTTTCGGTTCTTTTGACTTAA
AAACTTGGTTAACCTTAGCAGCGAGAAATTTATGTATGGCAGAGGAAGTTGAAATGGACATCTTAACCATCTGTAATGGA
TGTTATGGCTCTCTATATGAAGCCAATCATCTACTAAAAGAAAACGAAAAAGCAAGAAAAATGGTAAATGAAATACTCTC
CAAGTATGGATTAGAGTATAAAGGAAAAGTTAGAGTTAGACACTTACCTGAGGTTTTATACTACGATTTAGGAGTTGATA
GGATTAAAGAAGAGATAACAAACCCATTAAATGTAAATGTAGCAGTTCATTATGGCTGTCATTATTTAAAACCAACGGAT
ATTAAAAAATTGGAAAGTTCAGAAAGACCGAGATCTTTTGATGAACTTGTAGAGGCACTTGGAGCAGTGTCAGTCAATTA
TAAAGATAAAAATATGTGTTGTGGAGCTGGAGGAGGAGTCAGAGCAAGAAATTTAGATGTTGCCTTAAAAATGACTAAAA
CAAAATTGGAAAATATAAAAGAAGCAAAAGCCGATTGCATAACCGAAGTTTGTCCATTCTGCCACTTGCAATTTGACAGA
GGGCAAGTAGAGATAAAGGAAAAGTTTGGAGAGGAATATAATATTCCTGTGATACACTACTCCCAATTACTTGGGCTTGC
AATGGGAATGTCCCCGAAAGACGTTGCTTTGGACTTACACTTTATTCCAACAGATGAGTTTATCAAAAAAATAGATAGGC
ATTAA

Upstream 100 bases:

>100_bases
CACAGAAACAATGCAATTAAAACCAGTGGAATGGAAAGACATGTCAGAATAAGAAATAAAAACCAAAAATAAAAATAAAA
GTAAAGAAAGGTGTTTTAAT

Downstream 100 bases:

>100_bases
AATTTCTATTTAAAAAATTTAGAAAGTTATATATACTATCTAAAATCAAAAATATAATATATGAATTAGGTAGTAAAACC
ACTCAAAAAATAACTTATAA

Product: heterodisulfide reductase subunit HdrB1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MEFVFFLGCIAPNRYPGIEKATYITMEKLGIKLHPFEKASCCPAPGVFGSFDLKTWLTLAARNLCMAEEVEMDILTICNG
CYGSLYEANHLLKENEKARKMVNEILSKYGLEYKGKVRVRHLPEVLYYDLGVDRIKEEITNPLNVNVAVHYGCHYLKPTD
IKKLESSERPRSFDELVEALGAVSVNYKDKNMCCGAGGGVRARNLDVALKMTKTKLENIKEAKADCITEVCPFCHLQFDR
GQVEIKEKFGEEYNIPVIHYSQLLGLAMGMSPKDVALDLHFIPTDEFIKKIDRH

Sequences:

>Translated_294_residues
MEFVFFLGCIAPNRYPGIEKATYITMEKLGIKLHPFEKASCCPAPGVFGSFDLKTWLTLAARNLCMAEEVEMDILTICNG
CYGSLYEANHLLKENEKARKMVNEILSKYGLEYKGKVRVRHLPEVLYYDLGVDRIKEEITNPLNVNVAVHYGCHYLKPTD
IKKLESSERPRSFDELVEALGAVSVNYKDKNMCCGAGGGVRARNLDVALKMTKTKLENIKEAKADCITEVCPFCHLQFDR
GQVEIKEKFGEEYNIPVIHYSQLLGLAMGMSPKDVALDLHFIPTDEFIKKIDRH
>Mature_294_residues
MEFVFFLGCIAPNRYPGIEKATYITMEKLGIKLHPFEKASCCPAPGVFGSFDLKTWLTLAARNLCMAEEVEMDILTICNG
CYGSLYEANHLLKENEKARKMVNEILSKYGLEYKGKVRVRHLPEVLYYDLGVDRIKEEITNPLNVNVAVHYGCHYLKPTD
IKKLESSERPRSFDELVEALGAVSVNYKDKNMCCGAGGGVRARNLDVALKMTKTKLENIKEAKADCITEVCPFCHLQFDR
GQVEIKEKFGEEYNIPVIHYSQLLGLAMGMSPKDVALDLHFIPTDEFIKKIDRH

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrB may have a function in energy transduction

COG id: COG2048

COG function: function code C; Heterodisulfide reductase, subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HDRB1_METJA (Q58153)

Other databases:

- EMBL:   L77117
- PIR:   G64392
- RefSeq:   NP_247728.1
- GeneID:   1451620
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0743
- NMPDR:   fig|243232.1.peg.765
- TIGR:   MJ0743
- HOGENOM:   HBG513215
- OMA:   RAEVNEI
- ProtClustDB:   CLSK876313
- BioCyc:   MJAN243232:MJ_0743-MONOMER
- BRENDA:   1.8.98.1
- GO:   GO:0015948
- InterPro:   IPR017678
- InterPro:   IPR004017
- TIGRFAMs:   TIGR03288

Pfam domain/function: PF02754 CCG

EC number: =1.8.98.1

Molecular weight: Translated: 33310; Mature: 33310

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFVFFLGCIAPNRYPGIEKATYITMEKLGIKLHPFEKASCCPAPGVFGSFDLKTWLTLA
CCEEEEEEEECCCCCCCCCHHHEEEHHHHCCEECCCCCCCCCCCCCCCCCCHHHHHHHHH
ARNLCMAEEVEMDILTICNGCYGSLYEANHLLKENEKARKMVNEILSKYGLEYKGKVRVR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEE
HLPEVLYYDLGVDRIKEEITNPLNVNVAVHYGCHYLKPTDIKKLESSERPRSFDELVEAL
HHHHHHHHHCCHHHHHHHCCCCCEEEEEEEECEEECCCCCHHHHHCCCCCCCHHHHHHHH
GAVSVNYKDKNMCCGAGGGVRARNLDVALKMTKTKLENIKEAKADCITEVCPFCHLQFDR
CCEEECCCCCCEEECCCCCCEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
GQVEIKEKFGEEYNIPVIHYSQLLGLAMGMSPKDVALDLHFIPTDEFIKKIDRH
CCEEEHHHCCCCCCCCEEEHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCC
>Mature Secondary Structure
MEFVFFLGCIAPNRYPGIEKATYITMEKLGIKLHPFEKASCCPAPGVFGSFDLKTWLTLA
CCEEEEEEEECCCCCCCCCHHHEEEHHHHCCEECCCCCCCCCCCCCCCCCCHHHHHHHHH
ARNLCMAEEVEMDILTICNGCYGSLYEANHLLKENEKARKMVNEILSKYGLEYKGKVRVR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEE
HLPEVLYYDLGVDRIKEEITNPLNVNVAVHYGCHYLKPTDIKKLESSERPRSFDELVEAL
HHHHHHHHHCCHHHHHHHCCCCCEEEEEEEECEEECCCCCHHHHHCCCCCCCHHHHHHHH
GAVSVNYKDKNMCCGAGGGVRARNLDVALKMTKTKLENIKEAKADCITEVCPFCHLQFDR
CCEEECCCCCCEEECCCCCCEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
GQVEIKEKFGEEYNIPVIHYSQLLGLAMGMSPKDVALDLHFIPTDEFIKKIDRH
CCEEEHHHCCCCCCCCEEEHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087