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The map label for this gene is 15668875

Identifier: 15668875

GI number: 15668875

Start: 620123

End: 621367

Strand: Direct

Name: 15668875

Synonym: MJ0694

Alternate gene names: NA

Gene position: 620123-621367 (Clockwise)

Preceding gene: 15668869

Following gene: 15668878

Centisome position: 37.25

GC content: 31.97

Gene sequence:

>1245_bases
TTGATTTATGTTACTTTTACACCTTATGGAGCTTTTGGAGTTAAAGATAATAAAGAAGTTAGCGGATTGGAAGATATAGA
GTATAAAAAATTGTTTAATGAGGAAGAAATTCCAGATATAATGTTTAAATTAAAAACTCAGCCAAATAAAATAGCAGATG
AGTTAAAAGAGGAATGGGGAGATGAGATTAAATTAGAAACACTTAGCACTGAACCATTCAATATAGGGGAGTTTTTAAGA
AACAACTTATTTAAAGTTGGAAAAGAATTGGGATACTTCAACAACTATGATGAATTTAGAAAGAAGATGCATTATTGGAG
CACTGAGCTAACAAAGAAAGTTATAAAGAGCTATGCTCAACAAAAGGATAAAATCATTATTCAAGTTGCAGAGGCAATAT
CTGATTTGGATAAAACTCTAAACTTGTTATCTGAGAGATTGAGAGAGTGGTATTCCCTCTACTTCCCAGAGTTAGACCAC
TTAGTTAATAAACATGAAGTTTATGCTAACCTAATAACAAAATTAGGAAAAAGGAAAAACTTTACCAAGAGTCAGCTAAA
AAAAATCCTTCCTTCAAAATTAGCTGGGAAAATTGCTGAAGCCGCAAAAAATTCAATGGGAGGAGAATTGGAAGATTATG
ATTTAGATGTTATTGTTAAATTTGCTGAGGAAATAAATCACCTATATGAAAAAAGGAAGGAGCTATATAACTATTTAGAA
AAATTGATGAACGAAGAAGCTCCAAATATTACAAAACTTGCTGGTGTTTCCTTAGGAGCGAGATTAATAGGTTTAGCTGG
AGGATTGGAGAAATTGGCTAAGATGCCTGCTTCAACAATACAAGTTTTAGGTGCTGAGAAGGCTTTATTTGCCCATTTAA
GGATGGGTGTGGAGCCTCCAAAACATGGTATAATATATAATCACCCTTTAATTCAAGGTTCTCCACACTGGCAAAGAGGG
AAAATAGCAAGAGCTTTAGCATGTAAATTGGCTATAGCTGCAAGAGCTGATTATGTTGGGGATTATATTGCAGATGAACT
TTTAGAAAAGTTAAATAAGAGAGTTGAAGAGATTAGAAGAAAGTATCCAAAACCACCAAAGAAAAAGAAGAAAGAGAAAC
CTAAAGCAAAGAAAAAAGAAAAGAAAGGTAAGAAAGAAAAATCAAAGAAAAAAAAGGATAAGAAAAAAGATAAAAAAGGT
AAAAAAGAAAGGAAAGTTATAGGAAAAACAAAGAGTAGGAAATAA

Upstream 100 bases:

>100_bases
TTATTATGCTTTACTAATATAAGACATTTTGCAAAAAACTATTTATTTAAGAAAATTTTAATGTTGTTCTATATATAAAA
ACTTATCAGGGGGGATTATT

Downstream 100 bases:

>100_bases
TTACTTTTTACGATTTTTATTTTTTTCACGATAATGGACATACAGAACATACAATAATGCATCTATAACTACAATAGCAG
TTGATATAATCCACATTTTA

Product: C/D box methylation guide ribonucleoprotein complex aNOP56 subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MIYVTFTPYGAFGVKDNKEVSGLEDIEYKKLFNEEEIPDIMFKLKTQPNKIADELKEEWGDEIKLETLSTEPFNIGEFLR
NNLFKVGKELGYFNNYDEFRKKMHYWSTELTKKVIKSYAQQKDKIIIQVAEAISDLDKTLNLLSERLREWYSLYFPELDH
LVNKHEVYANLITKLGKRKNFTKSQLKKILPSKLAGKIAEAAKNSMGGELEDYDLDVIVKFAEEINHLYEKRKELYNYLE
KLMNEEAPNITKLAGVSLGARLIGLAGGLEKLAKMPASTIQVLGAEKALFAHLRMGVEPPKHGIIYNHPLIQGSPHWQRG
KIARALACKLAIAARADYVGDYIADELLEKLNKRVEEIRRKYPKPPKKKKKEKPKAKKKEKKGKKEKSKKKKDKKKDKKG
KKERKVIGKTKSRK

Sequences:

>Translated_414_residues
MIYVTFTPYGAFGVKDNKEVSGLEDIEYKKLFNEEEIPDIMFKLKTQPNKIADELKEEWGDEIKLETLSTEPFNIGEFLR
NNLFKVGKELGYFNNYDEFRKKMHYWSTELTKKVIKSYAQQKDKIIIQVAEAISDLDKTLNLLSERLREWYSLYFPELDH
LVNKHEVYANLITKLGKRKNFTKSQLKKILPSKLAGKIAEAAKNSMGGELEDYDLDVIVKFAEEINHLYEKRKELYNYLE
KLMNEEAPNITKLAGVSLGARLIGLAGGLEKLAKMPASTIQVLGAEKALFAHLRMGVEPPKHGIIYNHPLIQGSPHWQRG
KIARALACKLAIAARADYVGDYIADELLEKLNKRVEEIRRKYPKPPKKKKKEKPKAKKKEKKGKKEKSKKKKDKKKDKKG
KKERKVIGKTKSRK
>Mature_414_residues
MIYVTFTPYGAFGVKDNKEVSGLEDIEYKKLFNEEEIPDIMFKLKTQPNKIADELKEEWGDEIKLETLSTEPFNIGEFLR
NNLFKVGKELGYFNNYDEFRKKMHYWSTELTKKVIKSYAQQKDKIIIQVAEAISDLDKTLNLLSERLREWYSLYFPELDH
LVNKHEVYANLITKLGKRKNFTKSQLKKILPSKLAGKIAEAAKNSMGGELEDYDLDVIVKFAEEINHLYEKRKELYNYLE
KLMNEEAPNITKLAGVSLGARLIGLAGGLEKLAKMPASTIQVLGAEKALFAHLRMGVEPPKHGIIYNHPLIQGSPHWQRG
KIARALACKLAIAARADYVGDYIADELLEKLNKRVEEIRRKYPKPPKKKKKEKPKAKKKEKKGKKEKSKKKKDKKKDKKG
KKERKVIGKTKSRK

Specific function: Unknown

COG id: COG1498

COG function: function code J; Protein implicated in ribosomal biogenesis, Nop56p homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Nop domain

Homologues:

Organism=Homo sapiens, GI7706254, Length=232, Percent_Identity=39.2241379310345, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI32483374, Length=247, Percent_Identity=37.6518218623482, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI221136939, Length=257, Percent_Identity=29.1828793774319, Blast_Score=106, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17509449, Length=219, Percent_Identity=44.2922374429224, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17562296, Length=254, Percent_Identity=35.8267716535433, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17510923, Length=274, Percent_Identity=29.9270072992701, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324886, Length=268, Percent_Identity=39.9253731343284, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323226, Length=248, Percent_Identity=34.6774193548387, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI17137636, Length=293, Percent_Identity=37.542662116041, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI28572126, Length=247, Percent_Identity=41.7004048582996, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21357435, Length=298, Percent_Identity=30.8724832214765, Blast_Score=115, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y694_METJA (Q58105)

Other databases:

- EMBL:   L77117
- PIR:   F64386
- RefSeq:   NP_247678.1
- ProteinModelPortal:   Q58105
- SMR:   Q58105
- IntAct:   Q58105
- GeneID:   1451561
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0694
- NMPDR:   fig|243232.1.peg.715
- TIGR:   MJ0694
- HOGENOM:   HBG611715
- OMA:   RALPPKH
- ProtClustDB:   PRK14552
- BioCyc:   MJAN243232:MJ_0694-MONOMER
- InterPro:   IPR012976
- InterPro:   IPR002687
- SMART:   SM00931

Pfam domain/function: PF01798 Nop; PF08060 NOSIC

EC number: NA

Molecular weight: Translated: 47799; Mature: 47799

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYVTFTPYGAFGVKDNKEVSGLEDIEYKKLFNEEEIPDIMFKLKTQPNKIADELKEEWG
CEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCC
DEIKLETLSTEPFNIGEFLRNNLFKVGKELGYFNNYDEFRKKMHYWSTELTKKVIKSYAQ
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QKDKIIIQVAEAISDLDKTLNLLSERLREWYSLYFPELDHLVNKHEVYANLITKLGKRKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FTKSQLKKILPSKLAGKIAEAAKNSMGGELEDYDLDVIVKFAEEINHLYEKRKELYNYLE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLMNEEAPNITKLAGVSLGARLIGLAGGLEKLAKMPASTIQVLGAEKALFAHLRMGVEPP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
KHGIIYNHPLIQGSPHWQRGKIARALACKLAIAARADYVGDYIADELLEKLNKRVEEIRR
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYPKPPKKKKKEKPKAKKKEKKGKKEKSKKKKDKKKDKKGKKERKVIGKTKSRK
HCCCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MIYVTFTPYGAFGVKDNKEVSGLEDIEYKKLFNEEEIPDIMFKLKTQPNKIADELKEEWG
CEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCC
DEIKLETLSTEPFNIGEFLRNNLFKVGKELGYFNNYDEFRKKMHYWSTELTKKVIKSYAQ
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QKDKIIIQVAEAISDLDKTLNLLSERLREWYSLYFPELDHLVNKHEVYANLITKLGKRKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FTKSQLKKILPSKLAGKIAEAAKNSMGGELEDYDLDVIVKFAEEINHLYEKRKELYNYLE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLMNEEAPNITKLAGVSLGARLIGLAGGLEKLAKMPASTIQVLGAEKALFAHLRMGVEPP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
KHGIIYNHPLIQGSPHWQRGKIARALACKLAIAARADYVGDYIADELLEKLNKRVEEIRR
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYPKPPKKKKKEKPKAKKKEKKGKKEKSKKKKDKKKDKKGKKERKVIGKTKSRK
HCCCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087