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The map label for this gene is dapB [H]

Identifier: 15668598

GI number: 15668598

Start: 380914

End: 381786

Strand: Reverse

Name: dapB [H]

Synonym: MJ0422

Alternate gene names: 15668598

Gene position: 381786-380914 (Counterclockwise)

Preceding gene: 15668602

Following gene: 15668593

Centisome position: 22.93

GC content: 33.68

Gene sequence:

>873_bases
ATGCGAGTAATAATTCTAAAAATTAAGAAAATCTTTATGGTGATGATTATGATTAAAGTGGCAGTTACAGGAGCTTTAGG
AAGGATGGGAAGCAATATAATTAAAACCATAACTCAGCAAGAAGATATGAAAGTTGTTTGTGCATTTGAAGTTCCAAATC
ATCCAAAAAAAGGAGAGGATGTTGGAGAGTTAATAGGCATTGGTAAAATTGGAGTTCCATTATCAACTGCAGATGAGTTA
GATAAGGTTTTAAAAGAAACAAAGCCAGATGTATTGGTTGATTTTACCATAGCCCATGCATGTGTTGAAAATGTTAAAAT
AGCTGCTAAAAATGGGGTTAATTTAGTTATTGGGACTACTGGATTTACTGAAGAGCAAAAGGCAGAGATTGAAAAAGCAA
TAAAAGAAAATAATGTTGCTGCTGTAATATCTCAAAATTTTGCAATTGGAGTTAATATATTTTTCAAAACTTTAGAGTTT
TTAGCAAAGAAATTAGGGGATTATGATATTGAAATTATAGAGATGCATCATAGATATAAAAAGGACGCTCCTTCAGGAAC
TGCTTTGAGAGCAGCTGAGATTATAAAAGCTAATAGAGGAATTGAAAGTGTATTTGTTTATGGGAGATATGGAATGACTG
GAGAGAGAAAGAAGGAAGAGATTGGGATTCATGCTTTAAGGGGCGGGGATGTTGTAGGAGACCACACAGTTATATTTGCT
GGAGATGGAGAGAGGATTGAGCTAACTCACAGAGCAAGTAGTAGGCAAGCGTTTGTTAATGGAGTTATATTGGCTATAAG
ATACATTGCTGATAAAAAAGAAGGCATTTATAATACATTTGACGTTTTGGGATTGAATGAGATTAAGTTTTAA

Upstream 100 bases:

>100_bases
TCTTTTCTATTCACGAACATAACTATCCCATACATAATGCTGTTGATAAAGTATAATACTTAGCCTACATCATTTATATT
GCATCAACTATTTATAAATA

Downstream 100 bases:

>100_bases
AAATTCTAAATCGTTTATTAAAAATTTTTATTTCTCCCAACCAAAAATTTTAAATAACAAAAAACTTGTAATGATAAATA
AAGATATAATTGAGGTTATT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MRVIILKIKKIFMVMIMIKVAVTGALGRMGSNIIKTITQQEDMKVVCAFEVPNHPKKGEDVGELIGIGKIGVPLSTADEL
DKVLKETKPDVLVDFTIAHACVENVKIAAKNGVNLVIGTTGFTEEQKAEIEKAIKENNVAAVISQNFAIGVNIFFKTLEF
LAKKLGDYDIEIIEMHHRYKKDAPSGTALRAAEIIKANRGIESVFVYGRYGMTGERKKEEIGIHALRGGDVVGDHTVIFA
GDGERIELTHRASSRQAFVNGVILAIRYIADKKEGIYNTFDVLGLNEIKF

Sequences:

>Translated_290_residues
MRVIILKIKKIFMVMIMIKVAVTGALGRMGSNIIKTITQQEDMKVVCAFEVPNHPKKGEDVGELIGIGKIGVPLSTADEL
DKVLKETKPDVLVDFTIAHACVENVKIAAKNGVNLVIGTTGFTEEQKAEIEKAIKENNVAAVISQNFAIGVNIFFKTLEF
LAKKLGDYDIEIIEMHHRYKKDAPSGTALRAAEIIKANRGIESVFVYGRYGMTGERKKEEIGIHALRGGDVVGDHTVIFA
GDGERIELTHRASSRQAFVNGVILAIRYIADKKEGIYNTFDVLGLNEIKF
>Mature_290_residues
MRVIILKIKKIFMVMIMIKVAVTGALGRMGSNIIKTITQQEDMKVVCAFEVPNHPKKGEDVGELIGIGKIGVPLSTADEL
DKVLKETKPDVLVDFTIAHACVENVKIAAKNGVNLVIGTTGFTEEQKAEIEKAIKENNVAAVISQNFAIGVNIFFKTLEF
LAKKLGDYDIEIIEMHHRYKKDAPSGTALRAAEIIKANRGIESVFVYGRYGMTGERKKEEIGIHALRGGDVVGDHTVIFA
GDGERIELTHRASSRQAFVNGVILAIRYIADKKEGIYNTFDVLGLNEIKF

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=274, Percent_Identity=41.970802919708, Blast_Score=197, Evalue=9e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 31914; Mature: 31914

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIILKIKKIFMVMIMIKVAVTGALGRMGSNIIKTITQQEDMKVVCAFEVPNHPKKGED
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEECCCCCCCCCC
VGELIGIGKIGVPLSTADELDKVLKETKPDVLVDFTIAHACVENVKIAAKNGVNLVIGTT
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCEEEECCCCEEEEECC
GFTEEQKAEIEKAIKENNVAAVISQNFAIGVNIFFKTLEFLAKKLGDYDIEIIEMHHRYK
CCCHHHHHHHHHHHHHCCEEEEEECCEEEEHHHHHHHHHHHHHHHCCCCEEEEEEHHHHC
KDAPSGTALRAAEIIKANRGIESVFVYGRYGMTGERKKEEIGIHALRGGDVVGDHTVIFA
CCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCEEEECCCCEECCCEEEEE
GDGERIELTHRASSRQAFVNGVILAIRYIADKKEGIYNTFDVLGLNEIKF
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHCCC
>Mature Secondary Structure
MRVIILKIKKIFMVMIMIKVAVTGALGRMGSNIIKTITQQEDMKVVCAFEVPNHPKKGED
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEECCCCCCCCCC
VGELIGIGKIGVPLSTADELDKVLKETKPDVLVDFTIAHACVENVKIAAKNGVNLVIGTT
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCEEEECCCCEEEEECC
GFTEEQKAEIEKAIKENNVAAVISQNFAIGVNIFFKTLEFLAKKLGDYDIEIIEMHHRYK
CCCHHHHHHHHHHHHHCCEEEEEECCEEEEHHHHHHHHHHHHHHHCCCCEEEEEEHHHHC
KDAPSGTALRAAEIIKANRGIESVFVYGRYGMTGERKKEEIGIHALRGGDVVGDHTVIFA
CCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCEEEECCCCEECCCEEEEE
GDGERIELTHRASSRQAFVNGVILAIRYIADKKEGIYNTFDVLGLNEIKF
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]