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The map label for this gene is hypA

Identifier: 15668387

GI number: 15668387

Start: 204673

End: 205047

Strand: Direct

Name: hypA

Synonym: MJ0214

Alternate gene names: 15668387

Gene position: 204673-205047 (Clockwise)

Preceding gene: 15668386

Following gene: 15668398

Centisome position: 12.29

GC content: 31.2

Gene sequence:

>375_bases
ATGCATGAATTATCTTACGCCAATGCCATGCTTGAAGCAATATTAAACAGCATAAAAAAAGAGGAAGAAAAAGGAAAGAA
AATAAAAAAAGTTACAGAAATCAACTTAGAAGTTGGAGAACTAACATTTATCAATGTTGAGCAGTTAAAATTTGCATTTG
AAGTTATTGCTGAAGGAACTGTATGTGAGGGAGCTAAAATTAACGTTGAATTTATAAAACCAAAGTGTAAATGCTTAGAC
TGTGGATATGAGGGAGAACCAGAGATTTTAGATGAATTTGAGGTCTATTGCCCAAAGTGTAAAAGTATAAGATTAAAATT
ATCTGGAGGGAAGGAGTTTAATATAAAAAATGCCACAGTTGAGTATGAAGATTAA

Upstream 100 bases:

>100_bases
TCGGATTTTAAAATTATTAAGATTTTTATAGTTTTGATTAAACCTTTTTAAAAAGTTGGATTAAGGAAATTGTTATTAAA
GGGCTAAAATTGGGATAAAT

Downstream 100 bases:

>100_bases
AGAGAAAAAAGATAGCAGTCATTTTATTTAATATTAAAGCATAAACCTTATTTTCACATTAACTATTATTTAATGTATTA
TCCCCTACTAAATATTTTTT

Product: hydrogenase expression/formation protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MHELSYANAMLEAILNSIKKEEEKGKKIKKVTEINLEVGELTFINVEQLKFAFEVIAEGTVCEGAKINVEFIKPKCKCLD
CGYEGEPEILDEFEVYCPKCKSIRLKLSGGKEFNIKNATVEYED

Sequences:

>Translated_124_residues
MHELSYANAMLEAILNSIKKEEEKGKKIKKVTEINLEVGELTFINVEQLKFAFEVIAEGTVCEGAKINVEFIKPKCKCLD
CGYEGEPEILDEFEVYCPKCKSIRLKLSGGKEFNIKNATVEYED
>Mature_124_residues
MHELSYANAMLEAILNSIKKEEEKGKKIKKVTEINLEVGELTFINVEQLKFAFEVIAEGTVCEGAKINVEFIKPKCKCLD
CGYEGEPEILDEFEVYCPKCKSIRLKLSGGKEFNIKNATVEYED

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=121, Percent_Identity=28.099173553719, Blast_Score=68, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_METJA (Q57667)

Other databases:

- EMBL:   L77117
- PIR:   G64326
- RefSeq:   NP_247183.1
- ProteinModelPortal:   Q57667
- GeneID:   1451064
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0214
- NMPDR:   fig|243232.1.peg.220
- TIGR:   MJ0214
- HOGENOM:   HBG688671
- OMA:   MHELSYA
- ProtClustDB:   CLSK876114
- BioCyc:   MJAN243232:MJ_0214-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 14058; Mature: 14058

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELSYANAMLEAILNSIKKEEEKGKKIKKVTEINLEVGELTFINVEQLKFAFEVIAEGT
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCEEECCEEEEEHHHHHHHHHHHHCCC
VCEGAKINVEFIKPKCKCLDCGYEGEPEILDEFEVYCPKCKSIRLKLSGGKEFNIKNATV
CCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEECCEE
EYED
EECC
>Mature Secondary Structure
MHELSYANAMLEAILNSIKKEEEKGKKIKKVTEINLEVGELTFINVEQLKFAFEVIAEGT
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCEEECCEEEEEHHHHHHHHHHHHCCC
VCEGAKINVEFIKPKCKCLDCGYEGEPEILDEFEVYCPKCKSIRLKLSGGKEFNIKNATV
CCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEECCEE
EYED
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087