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The map label for this gene is hypC [C]

Identifier: 15668372

GI number: 15668372

Start: 192616

End: 192864

Strand: Reverse

Name: hypC [C]

Synonym: MJ0200

Alternate gene names: 15668372

Gene position: 192864-192616 (Counterclockwise)

Preceding gene: 15668373

Following gene: 15668360

Centisome position: 11.58

GC content: 32.13

Gene sequence:

>249_bases
ATGTGTCTGGCAATTCCATGTAAGGTTGTTGAGATTATAGAGGAAGATGGAGAGAAATACGCAATAGCTGAATATAAAGG
AGTTAAGCAAAAGGCAAAATTAACACTTTTAGATAAGGAGGTTAAAATAGGAGATTATATATTAATCCACACTGGCTATG
CTTTAGAAGTTTTAAGTGAAGAAGATGCTAAATTAAGTTTAGAAGCTTGGGAAGAATTGTTTAAAGCATTGGAAGAAATG
GAACAATAA

Upstream 100 bases:

>100_bases
CTTAAAAAGCAATAAAAAACATTTTTATTAATACTAAAAACAGATAATTTCATAAACAGAATTTTATATTAAAAGACTGT
AATTTATTTTTGGTGATAAA

Downstream 100 bases:

>100_bases
AAAAAGATTTTACAAAATAACAGAAAAGAATTTAAATTTGCTCTTTTATTCTGGTTCAACTTTTACAGCTCCTGTTGGAC
AGACATCTTCACAGACTCCA

Product: hydrogenase expression/formation protein HypC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 82

Protein sequence:

>82_residues
MCLAIPCKVVEIIEEDGEKYAIAEYKGVKQKAKLTLLDKEVKIGDYILIHTGYALEVLSEEDAKLSLEAWEELFKALEEM
EQ

Sequences:

>Translated_82_residues
MCLAIPCKVVEIIEEDGEKYAIAEYKGVKQKAKLTLLDKEVKIGDYILIHTGYALEVLSEEDAKLSLEAWEELFKALEEM
EQ
>Mature_82_residues
MCLAIPCKVVEIIEEDGEKYAIAEYKGVKQKAKLTLLDKEVKIGDYILIHTGYALEVLSEEDAKLSLEAWEELFKALEEM
EQ

Specific function: Is Required For The Formation Of All Three Hydrogenase Isoenzymes. May Bind To The Precursor Form Of The Large Subunit Of Dehydrogenases To Keep Them In A Conformation Accessible For Metal Incorporation. [C]

COG id: COG0298

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hupF/hypC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y200_METJA (Q57653)

Other databases:

- EMBL:   L77117
- PIR:   A64325
- RefSeq:   NP_247168.1
- ProteinModelPortal:   Q57653
- SMR:   Q57653
- GeneID:   1451049
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0200
- NMPDR:   fig|243232.1.peg.205
- TIGR:   MJ0200
- HOGENOM:   HBG556935
- OMA:   FAIQRLS
- ProtClustDB:   CLSK876107
- BioCyc:   MJAN243232:MJ_0200-MONOMER
- InterPro:   IPR019812
- InterPro:   IPR001109
- PRINTS:   PR00445
- TIGRFAMs:   TIGR00074

Pfam domain/function: PF01455 HupF_HypC

EC number: NA

Molecular weight: Translated: 9348; Mature: 9348

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS01097 HUPF_HYPC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLAIPCKVVEIIEEDGEKYAIAEYKGVKQKAKLTLLDKEVKIGDYILIHTGYALEVLSE
CEEECCHHHHHHHHHCCCEEEEHHHCCCCCHHEEEEECCCCCCCCEEEEECCCEEEEECC
EDAKLSLEAWEELFKALEEMEQ
CCCEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCLAIPCKVVEIIEEDGEKYAIAEYKGVKQKAKLTLLDKEVKIGDYILIHTGYALEVLSE
CEEECCHHHHHHHHHCCCEEEEHHHCCCCCHHEEEEECCCCCCCCEEEEECCCEEEEECC
EDAKLSLEAWEELFKALEEMEQ
CCCEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087