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The map label for this gene is 15668360

Identifier: 15668360

GI number: 15668360

Start: 185874

End: 186671

Strand: Reverse

Name: 15668360

Synonym: MJ0188

Alternate gene names: NA

Gene position: 186671-185874 (Counterclockwise)

Preceding gene: 15668372

Following gene: 15668359

Centisome position: 11.21

GC content: 31.83

Gene sequence:

>798_bases
ATGTCAGTAAAGGTATCTGAATATATGACAAAGAAGGTTGTTACTGTTTCAAAAGATAATACAGTTAAAGATGTTATTAA
ATTGTTGAAAGAGACTGGACACAATTCATTTCCTGTGGTTGAGAATGGAAAGCTAATAGGGATAGTTTCTGTTCATGATA
TTGTAGGAAAGGATGATAATGAGAAAGTAGAAAATGTAATGACAAAAAGGAAAGATATGGTTGTTACAACTCCTGATGCC
AATATAATGGATGTTGGTAGAATAATGTTTAGAACTGGTTTCTCAAAATTGCCAGTTGTTGATGAAGAAAATAATTTAGT
TGGAATTATATCTAATATGGATGTTATCAGGTCTCAAATAGAGAAAACCACGCCTAAAAAATTGGAAAATATAATCAAAA
CTTATAAAAGCTTAGGTTACAATTTGAGAGTTGAAAAAGAAGAGGTAGATGTTAATAAATTGAGACCAACACAGAATAAA
ATACACGCTGATGAGCTGGTTGGCAGAATGTATGAACTAAAAAAAGGTTTGGCAGAGCCAATAATTGCAATAAAAACAAA
AAGGGGAGATTATTATATATTGGTAGATGGACATCATAGGGCAGTAGCAGCGTATAAAATGGGAGTGCCGAAGTTGGATG
CCTATGTAATTTATTTAGACACTGATAAAAAGCTTGGTATAGAAAAGACAGCTGAGATTATGAATTTAAAATCACTGGAG
GATGTTAAGATTGTTGATAGTGATGACGAAAACAGTGTTAAGGTAATAAAATACAACAAAAATGGAGTATTGGGATAA

Upstream 100 bases:

>100_bases
ATAATGCCTTTAGGCATTTAAATGCCTTTAATAAAATATACAAACTGCGAAAGTTCTATTACAATATAAAAATTTAAAAA
TTTATGCTGATGGTGTCATT

Downstream 100 bases:

>100_bases
TTATGATAATTAGGGGAATAAGAGGGGCAAGGATAAATAATGAAATTTTTAATTTAGGTTTAAAGTTTCAAATTTTAAAC
GCTGATGTAGTAGCTACAAA

Product: inosine-5'-monophosphate dehydrogenase

Products: xanthosine 5'-phosphate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSVKVSEYMTKKVVTVSKDNTVKDVIKLLKETGHNSFPVVENGKLIGIVSVHDIVGKDDNEKVENVMTKRKDMVVTTPDA
NIMDVGRIMFRTGFSKLPVVDEENNLVGIISNMDVIRSQIEKTTPKKLENIIKTYKSLGYNLRVEKEEVDVNKLRPTQNK
IHADELVGRMYELKKGLAEPIIAIKTKRGDYYILVDGHHRAVAAYKMGVPKLDAYVIYLDTDKKLGIEKTAEIMNLKSLE
DVKIVDSDDENSVKVIKYNKNGVLG

Sequences:

>Translated_265_residues
MSVKVSEYMTKKVVTVSKDNTVKDVIKLLKETGHNSFPVVENGKLIGIVSVHDIVGKDDNEKVENVMTKRKDMVVTTPDA
NIMDVGRIMFRTGFSKLPVVDEENNLVGIISNMDVIRSQIEKTTPKKLENIIKTYKSLGYNLRVEKEEVDVNKLRPTQNK
IHADELVGRMYELKKGLAEPIIAIKTKRGDYYILVDGHHRAVAAYKMGVPKLDAYVIYLDTDKKLGIEKTAEIMNLKSLE
DVKIVDSDDENSVKVIKYNKNGVLG
>Mature_264_residues
SVKVSEYMTKKVVTVSKDNTVKDVIKLLKETGHNSFPVVENGKLIGIVSVHDIVGKDDNEKVENVMTKRKDMVVTTPDAN
IMDVGRIMFRTGFSKLPVVDEENNLVGIISNMDVIRSQIEKTTPKKLENIIKTYKSLGYNLRVEKEEVDVNKLRPTQNKI
HADELVGRMYELKKGLAEPIIAIKTKRGDYYILVDGHHRAVAAYKMGVPKLDAYVIYLDTDKKLGIEKTAEIMNLKSLED
VKIVDSDDENSVKVIKYNKNGVLG

Specific function: Unknown

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y188_METJA (Q57647)

Other databases:

- EMBL:   L77117
- PIR:   E64323
- RefSeq:   NP_247156.1
- ProteinModelPortal:   Q57647
- GeneID:   1451035
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0188
- NMPDR:   fig|243232.1.peg.193
- TIGR:   MJ0188
- HOGENOM:   HBG496823
- OMA:   GRIMFRT
- ProtClustDB:   CLSK862675
- BioCyc:   MJAN243232:MJ_0188-MONOMER
- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR003115
- InterPro:   IPR016427
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF004699
- SMART:   SM00116
- SMART:   SM00470

Pfam domain/function: PF00571 CBS; PF02195 ParBc; SSF110849 ParBc

EC number: 1.1.1.205

Molecular weight: Translated: 29851; Mature: 29720

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKVSEYMTKKVVTVSKDNTVKDVIKLLKETGHNSFPVVENGKLIGIVSVHDIVGKDDN
CCEEHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCEEEEEEEEHHHCCCCH
EKVENVMTKRKDMVVTTPDANIMDVGRIMFRTGFSKLPVVDEENNLVGIISNMDVIRSQI
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCEEEEECCHHHHHHHH
EKTTPKKLENIIKTYKSLGYNLRVEKEEVDVNKLRPTQNKIHADELVGRMYELKKGLAEP
HCCCHHHHHHHHHHHHHCCCEEEEEHHHCCHHHCCCCCHHCCHHHHHHHHHHHHHHHHCC
IIAIKTKRGDYYILVDGHHRAVAAYKMGVPKLDAYVIYLDTDKKLGIEKTAEIMNLKSLE
EEEEEECCCCEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCC
DVKIVDSDDENSVKVIKYNKNGVLG
CEEEECCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SVKVSEYMTKKVVTVSKDNTVKDVIKLLKETGHNSFPVVENGKLIGIVSVHDIVGKDDN
CEEHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCEEEEEEEEHHHCCCCH
EKVENVMTKRKDMVVTTPDANIMDVGRIMFRTGFSKLPVVDEENNLVGIISNMDVIRSQI
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCEEEEECCHHHHHHHH
EKTTPKKLENIIKTYKSLGYNLRVEKEEVDVNKLRPTQNKIHADELVGRMYELKKGLAEP
HCCCHHHHHHHHHHHHHCCCEEEEEHHHCCHHHCCCCCHHCCHHHHHHHHHHHHHHHHCC
IIAIKTKRGDYYILVDGHHRAVAAYKMGVPKLDAYVIYLDTDKKLGIEKTAEIMNLKSLE
EEEEEECCCCEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCC
DVKIVDSDDENSVKVIKYNKNGVLG
CEEEECCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: inosine 5'-phosphate; NAD+; H2O

Specific reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087