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The map label for this gene is 15668334

Identifier: 15668334

GI number: 15668334

Start: 165534

End: 166799

Strand: Direct

Name: 15668334

Synonym: MJ0162

Alternate gene names: NA

Gene position: 165534-166799 (Clockwise)

Preceding gene: 15668330

Following gene: 15668341

Centisome position: 9.94

GC content: 33.18

Gene sequence:

>1266_bases
ATGGTTTTATTAAAGTTTCATGGTGGTTGCCAGCAAATTGGGATGAGTTGTGTTGAGGTAGAAACACAAAAAGGGAGAGT
TTTATTGGATTGCGGAATGTCTCCAGACACTGGAGAAATACCTAAGGTAGATGATAAAGCAGTAGATGCAGTTATTGTTT
CCCATGCTCATCTTGACCATTGTGGAGCAATCCCATTTTATAAATTCAAAAAGATTTATTGCACACATCCAACAGCTGAT
TTAATGTTTATAACTTGGAGAGATACTCTAAATTTAACAAAAGCTTATAAAGAAGAAGACATTCAGCATGCTATGGAAAA
TATTGAGTGCCTAAATTACTATGAGGAAAGGCAAATAACTGAAAACATTAAATTTAAATTTTACAATGCCGGGCATATAT
TGGGAAGTGCTTCCATATACTTGGAAGTGGATGGGAAAAAAATTCTCTATACTGGGGACATAAATGAAGGAGTTTCAAGA
ACATTACTCCCTGCAGATACAGATATCGATGAGATTGATGTCCTAATTATAGAATCTACTTATGGATCTCCATTGGATAT
AAAGCCAGCAAGAAAAACTTTAGAGAGGCAATTAATTGAGGAAATATCTGAAACAATAGAAAATGGAGGAAAAGTAATAA
TCCCAGTTTTTGCAATTGGTAGAGCTCAAGAGATATTGTTGATTATAAACAACTATATTAGAAGTGGAAAGTTAAGGGAT
GTGCCAATATATACTGACGGCTCCCTAATTCATGCAACTGCTGTTTATATGAGCTATATAAATTGGCTAAATCCAAAAAT
AAAAAATATGGTTGAGAATAGAATTAATCCATTTGGTGAGATAAAGAAGGCAGATGAAAGCTTAGTATTTAATAAAGAGC
CTTGTATTATTGTTTCAACTTCAGGGATGGTTCAAGGAGGACCGGTATTAAAATATTTAAAGTTATTGAAAGACCCAAAA
AACAAGCTTATATTAACTGGTTATCAGGCAGAGGGAACATTAGGAAGGGAATTAGAAGAGGGAGCTAAAGAAATTCAGCC
ATTTAAAAATAAAATCCCTATAAGGGGAAAAGTTGTTAAAATAGAATTTTCTGCTCATGGTGATTATAATTCATTAGTTA
GATATATAAAGAAGATTCCTAAACCAGAAAAAGCTATAGTTATGCATGGGGAGAGATATCAATCATTATCATTCGCTATG
ACTATTTGGAAGACATTAAAGATTCCAACCTTTGTTCCTGTTAGAGGAACAATATTGCCAATATAA

Upstream 100 bases:

>100_bases
AATTTTCTTTTAATCTTAACTTAATTTTTGGTTTCCTATTCTTTGCCTGGGTAATAGGATTTATCCAAATAAAATATATA
TAAATTTTTGGGATGGTAGT

Downstream 100 bases:

>100_bases
ATTATAAAATTTTTAAATACTCAATAATGCCTCCTCTGGAATTTCTTGCTCTATGGTTGTAATTGTTGAGAAATACTTTT
TGAGAACTCCTGTTATTCTT

Product: putative mRNA 3'-end processing factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MVLLKFHGGCQQIGMSCVEVETQKGRVLLDCGMSPDTGEIPKVDDKAVDAVIVSHAHLDHCGAIPFYKFKKIYCTHPTAD
LMFITWRDTLNLTKAYKEEDIQHAMENIECLNYYEERQITENIKFKFYNAGHILGSASIYLEVDGKKILYTGDINEGVSR
TLLPADTDIDEIDVLIIESTYGSPLDIKPARKTLERQLIEEISETIENGGKVIIPVFAIGRAQEILLIINNYIRSGKLRD
VPIYTDGSLIHATAVYMSYINWLNPKIKNMVENRINPFGEIKKADESLVFNKEPCIIVSTSGMVQGGPVLKYLKLLKDPK
NKLILTGYQAEGTLGRELEEGAKEIQPFKNKIPIRGKVVKIEFSAHGDYNSLVRYIKKIPKPEKAIVMHGERYQSLSFAM
TIWKTLKIPTFVPVRGTILPI

Sequences:

>Translated_421_residues
MVLLKFHGGCQQIGMSCVEVETQKGRVLLDCGMSPDTGEIPKVDDKAVDAVIVSHAHLDHCGAIPFYKFKKIYCTHPTAD
LMFITWRDTLNLTKAYKEEDIQHAMENIECLNYYEERQITENIKFKFYNAGHILGSASIYLEVDGKKILYTGDINEGVSR
TLLPADTDIDEIDVLIIESTYGSPLDIKPARKTLERQLIEEISETIENGGKVIIPVFAIGRAQEILLIINNYIRSGKLRD
VPIYTDGSLIHATAVYMSYINWLNPKIKNMVENRINPFGEIKKADESLVFNKEPCIIVSTSGMVQGGPVLKYLKLLKDPK
NKLILTGYQAEGTLGRELEEGAKEIQPFKNKIPIRGKVVKIEFSAHGDYNSLVRYIKKIPKPEKAIVMHGERYQSLSFAM
TIWKTLKIPTFVPVRGTILPI
>Mature_421_residues
MVLLKFHGGCQQIGMSCVEVETQKGRVLLDCGMSPDTGEIPKVDDKAVDAVIVSHAHLDHCGAIPFYKFKKIYCTHPTAD
LMFITWRDTLNLTKAYKEEDIQHAMENIECLNYYEERQITENIKFKFYNAGHILGSASIYLEVDGKKILYTGDINEGVSR
TLLPADTDIDEIDVLIIESTYGSPLDIKPARKTLERQLIEEISETIENGGKVIIPVFAIGRAQEILLIINNYIRSGKLRD
VPIYTDGSLIHATAVYMSYINWLNPKIKNMVENRINPFGEIKKADESLVFNKEPCIIVSTSGMVQGGPVLKYLKLLKDPK
NKLILTGYQAEGTLGRELEEGAKEIQPFKNKIPIRGKVVKIEFSAHGDYNSLVRYIKKIPKPEKAIVMHGERYQSLSFAM
TIWKTLKIPTFVPVRGTILPI

Specific function: Unknown

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family

Homologues:

Organism=Homo sapiens, GI7706427, Length=418, Percent_Identity=34.688995215311, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI33300633, Length=436, Percent_Identity=30.2752293577982, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI34101288, Length=371, Percent_Identity=25.0673854447439, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI32566029, Length=415, Percent_Identity=32.0481927710843, Blast_Score=214, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI32564696, Length=445, Percent_Identity=30.3370786516854, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17559452, Length=373, Percent_Identity=24.3967828418231, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323307, Length=450, Percent_Identity=29.5555555555556, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24648013, Length=411, Percent_Identity=34.7931873479319, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI21358523, Length=437, Percent_Identity=30.2059496567506, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21358013, Length=374, Percent_Identity=25.1336898395722, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y162_METJA (Q57626)

Other databases:

- EMBL:   L77117
- PIR:   C64320
- RefSeq:   NP_247130.1
- ProteinModelPortal:   Q57626
- GeneID:   1451009
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0162
- NMPDR:   fig|243232.1.peg.167
- TIGR:   MJ0162
- HOGENOM:   HBG402464
- OMA:   TFHDAGH
- ProtClustDB:   CLSK876093
- BioCyc:   MJAN243232:MJ_0162-MONOMER
- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108
- SMART:   SM00849

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL

EC number: NA

Molecular weight: Translated: 47478; Mature: 47478

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLKFHGGCQQIGMSCVEVETQKGRVLLDCGMSPDTGEIPKVDDKAVDAVIVSHAHLDH
CEEEEECCCHHHHCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHEEHHCCHHH
CGAIPFYKFKKIYCTHPTADLMFITWRDTLNLTKAYKEEDIQHAMENIECLNYYEERQIT
CCCCCCHHEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ENIKFKFYNAGHILGSASIYLEVDGKKILYTGDINEGVSRTLLPADTDIDEIDVLIIEST
CCCEEEEEECCEEEECEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECC
YGSPLDIKPARKTLERQLIEEISETIENGGKVIIPVFAIGRAQEILLIINNYIRSGKLRD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHEEHHHHCCCCCCC
VPIYTDGSLIHATAVYMSYINWLNPKIKNMVENRINPFGEIKKADESLVFNKEPCIIVST
CEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCEEECCCCEEEEEC
SGMVQGGPVLKYLKLLKDPKNKLILTGYQAEGTLGRELEEGAKEIQPFKNKIPIRGKVVK
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCHHHHCCCCCEEEEE
IEFSAHGDYNSLVRYIKKIPKPEKAIVMHGERYQSLSFAMTIWKTLKIPTFVPVRGTILP
EEEECCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCEEEC
I
C
>Mature Secondary Structure
MVLLKFHGGCQQIGMSCVEVETQKGRVLLDCGMSPDTGEIPKVDDKAVDAVIVSHAHLDH
CEEEEECCCHHHHCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHEEHHCCHHH
CGAIPFYKFKKIYCTHPTADLMFITWRDTLNLTKAYKEEDIQHAMENIECLNYYEERQIT
CCCCCCHHEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ENIKFKFYNAGHILGSASIYLEVDGKKILYTGDINEGVSRTLLPADTDIDEIDVLIIEST
CCCEEEEEECCEEEECEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECC
YGSPLDIKPARKTLERQLIEEISETIENGGKVIIPVFAIGRAQEILLIINNYIRSGKLRD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHEEHHHHCCCCCCC
VPIYTDGSLIHATAVYMSYINWLNPKIKNMVENRINPFGEIKKADESLVFNKEPCIIVST
CEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCEEECCCCEEEEEC
SGMVQGGPVLKYLKLLKDPKNKLILTGYQAEGTLGRELEEGAKEIQPFKNKIPIRGKVVK
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCHHHHCCCCCEEEEE
IEFSAHGDYNSLVRYIKKIPKPEKAIVMHGERYQSLSFAMTIWKTLKIPTFVPVRGTILP
EEEECCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCEEEC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087