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The map label for this gene is tauB [C]

Identifier: 30995461

GI number: 30995461

Start: 1686173

End: 1686790

Strand: Reverse

Name: tauB [C]

Synonym: HI1618

Alternate gene names: 30995461

Gene position: 1686790-1686173 (Counterclockwise)

Preceding gene: 16273510

Following gene: 16273504

Centisome position: 92.17

GC content: 38.03

Gene sequence:

>618_bases
ATGTTAGCTGTAAATAATCTTTGTATAGAACGCAATGGTAGAGCGATTATTCAAGATTTGAGTTTTACCTTGGAAGGTCA
AAAACGCCTTTTCGTACAAGGGGAAATTGGTTCAGGAAAAACCACTTTACTGCTTGCTTTGTTGGGATTTGTTCCTGTAA
CCAAAGGGGAAATTAAACTATTTGGCAAAGTTTGTCGTAAAGAAAAAGATTTTGCGCCATTTCGTGGCACGATTGGCATT
TGTTTTCAAAATGCGGATGATCAACTTTTTGGCCCAACAGTATTGGATGATATTGCCTTCGGGCCATTAAACCAAAATGT
GCCTAGAGAGCAGGCGTATCATATCGCAGAGCAGCAATTAGAACGTCTTGGTATCACACGTTTAAAAGATCGTATGGTAC
ATACCTTATCTGGTGGTGAGAAAAATTTTACCGCACTTGCAGGTGTCTTAGCGATGCAGCCAAAAATCTTATTATTAGAT
GAACCCACCAATGGATTAGATCGAAAAAATACTGAAAAATTGACCGCACTTTTGCGAGAACTTTCCTTACCCATTTTGAT
TTCATCCCATCATCATGGATTTATTAACGAATTAGCCACAGAAATTATCAGTTTATGA

Upstream 100 bases:

>100_bases
GTCGCTTTATTATTGATTCATGCCCTGCTGAAAGCTGAAACGGCGCAAATGGCGTTAAAATGTCGTGGTTTTCAGTTCGG
CAAAAAGAGAGAAAAATAAC

Downstream 100 bases:

>100_bases
TTTCTATATCCATTAGGTAAAAATGCGGCTGTGATTGGTGAAGTAATAACCGATAAAAAAGTGCGTTTAGTAGGCATTTT
TGGACAAAGTCGATTGTTAG

Product: ABC transporter ATP-binding protein

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MLAVNNLCIERNGRAIIQDLSFTLEGQKRLFVQGEIGSGKTTLLLALLGFVPVTKGEIKLFGKVCRKEKDFAPFRGTIGI
CFQNADDQLFGPTVLDDIAFGPLNQNVPREQAYHIAEQQLERLGITRLKDRMVHTLSGGEKNFTALAGVLAMQPKILLLD
EPTNGLDRKNTEKLTALLRELSLPILISSHHHGFINELATEIISL

Sequences:

>Translated_205_residues
MLAVNNLCIERNGRAIIQDLSFTLEGQKRLFVQGEIGSGKTTLLLALLGFVPVTKGEIKLFGKVCRKEKDFAPFRGTIGI
CFQNADDQLFGPTVLDDIAFGPLNQNVPREQAYHIAEQQLERLGITRLKDRMVHTLSGGEKNFTALAGVLAMQPKILLLD
EPTNGLDRKNTEKLTALLRELSLPILISSHHHGFINELATEIISL
>Mature_205_residues
MLAVNNLCIERNGRAIIQDLSFTLEGQKRLFVQGEIGSGKTTLLLALLGFVPVTKGEIKLFGKVCRKEKDFAPFRGTIGI
CFQNADDQLFGPTVLDDIAFGPLNQNVPREQAYHIAEQQLERLGITRLKDRMVHTLSGGEKNFTALAGVLAMQPKILLLD
EPTNGLDRKNTEKLTALLRELSLPILISSHHHGFINELATEIISL

Specific function: Part Of A Binding-Protein-Dependent Transport System For Taurine. Probably Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1122

COG function: function code P; ABC-type cobalt transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI9955963, Length=176, Percent_Identity=31.25, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI27262624, Length=152, Percent_Identity=32.2368421052632, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI27262626, Length=152, Percent_Identity=32.2368421052632, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI156105685, Length=172, Percent_Identity=32.5581395348837, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI45446740, Length=178, Percent_Identity=28.6516853932584, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI47078218, Length=178, Percent_Identity=28.6516853932584, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1786563, Length=209, Percent_Identity=34.4497607655502, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787712, Length=165, Percent_Identity=32.7272727272727, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI87081791, Length=178, Percent_Identity=34.2696629213483, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1787029, Length=209, Percent_Identity=28.7081339712919, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1786872, Length=180, Percent_Identity=30, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1788761, Length=196, Percent_Identity=34.6938775510204, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789593, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788225, Length=214, Percent_Identity=27.5700934579439, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789672, Length=194, Percent_Identity=26.8041237113402, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788506, Length=224, Percent_Identity=28.125, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI145693107, Length=232, Percent_Identity=29.3103448275862, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786703, Length=166, Percent_Identity=32.5301204819277, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789873, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786698, Length=195, Percent_Identity=29.7435897435897, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1787089, Length=172, Percent_Identity=29.6511627906977, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787500, Length=186, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789962, Length=195, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786345, Length=185, Percent_Identity=30.8108108108108, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786398, Length=175, Percent_Identity=30.8571428571429, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786654, Length=200, Percent_Identity=26.5, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790544, Length=193, Percent_Identity=27.4611398963731, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=203, Percent_Identity=29.5566502463054, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081834, Length=192, Percent_Identity=29.1666666666667, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787370, Length=188, Percent_Identity=30.8510638297872, Blast_Score=61, Evalue=4e-11,
Organism=Escherichia coli, GI1786319, Length=163, Percent_Identity=28.8343558282209, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1786975, Length=202, Percent_Identity=28.2178217821782, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1787143, Length=185, Percent_Identity=28.1081081081081, Blast_Score=60, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=188, Percent_Identity=30.3191489361702, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=192, Percent_Identity=29.6875, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193209708, Length=179, Percent_Identity=30.7262569832402, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=175, Percent_Identity=31.4285714285714, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574150, Length=178, Percent_Identity=29.7752808988764, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI116007328, Length=178, Percent_Identity=29.7752808988764, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17647959, Length=185, Percent_Identity=34.0540540540541, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574533, Length=182, Percent_Identity=31.3186813186813, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1618_HAEIN (P45275)

Other databases:

- EMBL:   L42023
- PIR:   A64133
- RefSeq:   NP_439760.2
- ProteinModelPortal:   P45275
- SMR:   P45275
- GeneID:   950842
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1618
- NMPDR:   fig|71421.1.peg.1534
- TIGR:   HI_1618
- HOGENOM:   HBG758042
- OMA:   ESGLAHR
- ProtClustDB:   CLSK918308
- BioCyc:   HINF71421:HI_1618-MONOMER
- GO:   GO:0006810
- InterPro:   IPR003439
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 22687; Mature: 22687

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVNNLCIERNGRAIIQDLSFTLEGQKRLFVQGEIGSGKTTLLLALLGFVPVTKGEIKL
CCEECCEEEECCCCEEEEHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHH
FGKVCRKEKDFAPFRGTIGICFQNADDQLFGPTVLDDIAFGPLNQNVPREQAYHIAEQQL
HHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ERLGITRLKDRMVHTLSGGEKNFTALAGVLAMQPKILLLDEPTNGLDRKNTEKLTALLRE
HHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHH
LSLPILISSHHHGFINELATEIISL
CCCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLAVNNLCIERNGRAIIQDLSFTLEGQKRLFVQGEIGSGKTTLLLALLGFVPVTKGEIKL
CCEECCEEEECCCCEEEEHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHH
FGKVCRKEKDFAPFRGTIGICFQNADDQLFGPTVLDDIAFGPLNQNVPREQAYHIAEQQL
HHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ERLGITRLKDRMVHTLSGGEKNFTALAGVLAMQPKILLLDEPTNGLDRKNTEKLTALLRE
HHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHH
LSLPILISSHHHGFINELATEIISL
CCCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800