Click here to switch to the map view.

The map label for this gene is ribH [H]

Identifier: 30995441

GI number: 30995441

Start: 1383211

End: 1383684

Strand: Direct

Name: ribH [H]

Synonym: HI1303

Alternate gene names: 30995441

Gene position: 1383211-1383684 (Clockwise)

Preceding gene: 16273212

Following gene: 16273216

Centisome position: 75.58

GC content: 39.66

Gene sequence:

>474_bases
ATGAAAGTTTTAGAAGGCTCAGTTGCAGCACCTAATGCAAAAGTTGCAGTAGTAATTGCTCGTTTTAACAGTTTTATTAA
TGAAAGTTTATTAGAAGGCGCAATTGATGCATTAAAACGTATCGGCCAAGTGAAAGATGAAAATATCACTATCGTGCGTA
CCCCGGGTGCGTATGAGTTGCCATTAGTTGCTCGTCGTTTAGCTGAAAGTAAAAAATTTGATGCGATTGTGGCATTAGGT
ACAGTTATCCGTGGTGGTACAGCACATTTTGAATATGTAGCAGGAGAAGCAAGCAGCGGTTTAGGAAAAGTTGCAATGGA
TGCTGAAATCCCTGTCGCTTTTGGTGTATTAACCACAGAAAATATTGAACAGGCGATTGAACGTGCTGGTACTAAAGCAG
GAAATAAAGGTGCAGAAGCAGCCTTAACTGCACTTGAAATGGTTAATCTTATTCAACAAATTGATGCGGCATAA

Upstream 100 bases:

>100_bases
GTCCTAAATAAAATAGGGTAAAGCCTTATTAATATTGAATATACGCGATTTTATGTTAAAATCTCGGGTCAAATCATTAT
GGCTAATAATAGGAAAAAAT

Downstream 100 bases:

>100_bases
ATCATGACAGAACAAAAACAAGTGAAAAAGCCTTCTGCTCGTCGTCGTGCGCGTGAGTGTACTGTTCAAGCCTTGTATTC
TTGGGCGGTATCCGGTAATA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKVLEGSVAAPNAKVAVVIARFNSFINESLLEGAIDALKRIGQVKDENITIVRTPGAYELPLVARRLAESKKFDAIVALG
TVIRGGTAHFEYVAGEASSGLGKVAMDAEIPVAFGVLTTENIEQAIERAGTKAGNKGAEAALTALEMVNLIQQIDAA

Sequences:

>Translated_157_residues
MKVLEGSVAAPNAKVAVVIARFNSFINESLLEGAIDALKRIGQVKDENITIVRTPGAYELPLVARRLAESKKFDAIVALG
TVIRGGTAHFEYVAGEASSGLGKVAMDAEIPVAFGVLTTENIEQAIERAGTKAGNKGAEAALTALEMVNLIQQIDAA
>Mature_157_residues
MKVLEGSVAAPNAKVAVVIARFNSFINESLLEGAIDALKRIGQVKDENITIVRTPGAYELPLVARRLAESKKFDAIVALG
TVIRGGTAHFEYVAGEASSGLGKVAMDAEIPVAFGVLTTENIEQAIERAGTKAGNKGAEAALTALEMVNLIQQIDAA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=156, Percent_Identity=76.2820512820513, Blast_Score=244, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6324429, Length=155, Percent_Identity=33.5483870967742, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16419; Mature: 16419

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLEGSVAAPNAKVAVVIARFNSFINESLLEGAIDALKRIGQVKDENITIVRTPGAYEL
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
PLVARRLAESKKFDAIVALGTVIRGGTAHFEYVAGEASSGLGKVAMDAEIPVAFGVLTTE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEHCCHH
NIEQAIERAGTKAGNKGAEAALTALEMVNLIQQIDAA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVLEGSVAAPNAKVAVVIARFNSFINESLLEGAIDALKRIGQVKDENITIVRTPGAYEL
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
PLVARRLAESKKFDAIVALGTVIRGGTAHFEYVAGEASSGLGKVAMDAEIPVAFGVLTTE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEHCCHH
NIEQAIERAGTKAGNKGAEAALTALEMVNLIQQIDAA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA