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The map label for this gene is hitB [H]

Identifier: 30995355

GI number: 30995355

Start: 105476

End: 106912

Strand: Direct

Name: hitB [H]

Synonym: HI0098

Alternate gene names: 30995355

Gene position: 105476-106912 (Clockwise)

Preceding gene: 30995354

Following gene: 16272073

Centisome position: 5.76

GC content: 39.18

Gene sequence:

>1437_bases
TTGCGTGCGACAGAAGTGGGATTAACGCGAAGTGTTGAGCTATTGTTTCGCCCTCGAATGGCTGAATTATTAAGCAATAC
AATGCTTTTAATGGTTTGTGTAACTATCGGTGCTATTTCACTTGGCACGTTTTGTGCTTTTTTACTTGAACGTTATCGCT
TTTTCGGTAAAGCTTTTTTTGAAGTGGCAATGACGTTACCCCTTTGTATTCCCGCCTTTGTAAGTGGTTTTACTTGGATC
AGCCTCACATTCCGCGTTGAGGTTTTTTGGGGAACAATTGGTATTATGACATTAAGTTCATTTCCTTTGGCTTATTTGCC
CGTTTCCGCCATACTAAAAAGACTTGATCGTTCTCTTGAAGAAGTAAGCCTTTCGCTTGGTAAAAGCCCTGTGTATACCT
TTTGGTATGCTATTTCCCCGCAACTTAAACCCGCCATTGGTAGTAGTATCTTACTGATTGCTTTACATATGTTGGTCGAA
TTTGGTGCAGTGTCAATTTTAAATTATCAAACCTTTACCACTGCCATTTTCCAAGAATATGAAATGTCTTTTAACAACAG
CACTGCTGCATTATTATCCGCCGTTTTAATGGCGATTTGTATACTTATTGTTTTTGGGGAAATTTTCTTTCGTGGAAAAC
AAACCCTTTACCACAGTGGAAAAGGCGTTACTCGTCCTTATCTCGTAAAAACACTTTCCTTTGGAAAACAATGTTTAACC
TTCGGATTTTTCTCTAGCATATTCATTTTAAGCATTGGCGTGCCTGTGATTATGTTAATTTACTGGCTTATTGTGGGAAC
TTCACTTGAAAGTGCGGGTGATTTTTCAGAATTTTTATCGGCATTCAGCAATTCATTTATCATTTCAGGCTTAGGCGCAT
TGCTTACCGTAATGTGCGCCTTGCCATTAGTTTGGGCAGCTGTTCGTTACCGTAGTTATTTAACGATTTGGATCGACCGC
TTGCCATATCTATTACACGCTGTGCCAGGCTTAGTCATTGCCTTATCATTAGTCTATTTTTCCATCCATTACGCTAACGA
CCTATATCAAACCTTTTTTGTGATTATCATTGCCTACTTTATGCTCTATTTGCCAATGGCACAAACTACATTAAGAGCGT
CTTTAGAGCAACTTTCCGATCAAATTGAAAAAGTCGGACAAAGTCTTGGGCGAAACCCTTTCTATATTTTTCGCACCTTG
ACGCTACCAGCCATATTACCAGGTGTGGCAGCCGCATTTGCTTTGGTTTTTTTGAATTTAATGAAAGAGCTTACCGCGAC
GCTTTTGCTCACATCAAATGATATTAAAACCTTATCCATTGCTGTGTGGGAACATACCAGCGATGCACAATATGCTGCTG
CCACCCCTTATGCGTTAATGCTCGTTCTTTTTTCGGGTATTCCTGTATTTTTATTGAAAAAATATGCGTTTAAATAA

Upstream 100 bases:

>100_bases
CTAAAAGGATTTAACTTTGCCTCGCAGACCGCCATTCTGGCTCACTTTACTTATCATCTTAATCGGGCTTCCGTTATGTT
TGCCGTTTCTGTATGTCATT

Downstream 100 bases:

>100_bases
AATGATAAATAATCCGTTATTAACCGTTAAAAATCTCAATAAATTTTTTAATGAACAACAAGTTCTGCACGATATTTCAT
TCAGCTTACAACGCGGAGAA

Product: iron(III) ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: Iron(III)-transport system permease protein fbpB 2 [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MRATEVGLTRSVELLFRPRMAELLSNTMLLMVCVTIGAISLGTFCAFLLERYRFFGKAFFEVAMTLPLCIPAFVSGFTWI
SLTFRVEVFWGTIGIMTLSSFPLAYLPVSAILKRLDRSLEEVSLSLGKSPVYTFWYAISPQLKPAIGSSILLIALHMLVE
FGAVSILNYQTFTTAIFQEYEMSFNNSTAALLSAVLMAICILIVFGEIFFRGKQTLYHSGKGVTRPYLVKTLSFGKQCLT
FGFFSSIFILSIGVPVIMLIYWLIVGTSLESAGDFSEFLSAFSNSFIISGLGALLTVMCALPLVWAAVRYRSYLTIWIDR
LPYLLHAVPGLVIALSLVYFSIHYANDLYQTFFVIIIAYFMLYLPMAQTTLRASLEQLSDQIEKVGQSLGRNPFYIFRTL
TLPAILPGVAAAFALVFLNLMKELTATLLLTSNDIKTLSIAVWEHTSDAQYAAATPYALMLVLFSGIPVFLLKKYAFK

Sequences:

>Translated_478_residues
MRATEVGLTRSVELLFRPRMAELLSNTMLLMVCVTIGAISLGTFCAFLLERYRFFGKAFFEVAMTLPLCIPAFVSGFTWI
SLTFRVEVFWGTIGIMTLSSFPLAYLPVSAILKRLDRSLEEVSLSLGKSPVYTFWYAISPQLKPAIGSSILLIALHMLVE
FGAVSILNYQTFTTAIFQEYEMSFNNSTAALLSAVLMAICILIVFGEIFFRGKQTLYHSGKGVTRPYLVKTLSFGKQCLT
FGFFSSIFILSIGVPVIMLIYWLIVGTSLESAGDFSEFLSAFSNSFIISGLGALLTVMCALPLVWAAVRYRSYLTIWIDR
LPYLLHAVPGLVIALSLVYFSIHYANDLYQTFFVIIIAYFMLYLPMAQTTLRASLEQLSDQIEKVGQSLGRNPFYIFRTL
TLPAILPGVAAAFALVFLNLMKELTATLLLTSNDIKTLSIAVWEHTSDAQYAAATPYALMLVLFSGIPVFLLKKYAFK
>Mature_478_residues
MRATEVGLTRSVELLFRPRMAELLSNTMLLMVCVTIGAISLGTFCAFLLERYRFFGKAFFEVAMTLPLCIPAFVSGFTWI
SLTFRVEVFWGTIGIMTLSSFPLAYLPVSAILKRLDRSLEEVSLSLGKSPVYTFWYAISPQLKPAIGSSILLIALHMLVE
FGAVSILNYQTFTTAIFQEYEMSFNNSTAALLSAVLMAICILIVFGEIFFRGKQTLYHSGKGVTRPYLVKTLSFGKQCLT
FGFFSSIFILSIGVPVIMLIYWLIVGTSLESAGDFSEFLSAFSNSFIISGLGALLTVMCALPLVWAAVRYRSYLTIWIDR
LPYLLHAVPGLVIALSLVYFSIHYANDLYQTFFVIIIAYFMLYLPMAQTTLRASLEQLSDQIEKVGQSLGRNPFYIFRTL
TLPAILPGVAAAFALVFLNLMKELTATLLLTSNDIKTLSIAVWEHTSDAQYAAATPYALMLVLFSGIPVFLLKKYAFK

Specific function: Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1178

COG function: function code P; ABC-type Fe3+ transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transmembrane type-1 domains [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=179, Percent_Identity=27.3743016759777, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 53274; Mature: 53274

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATEVGLTRSVELLFRPRMAELLSNTMLLMVCVTIGAISLGTFCAFLLERYRFFGKAFF
CCCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAMTLPLCIPAFVSGFTWISLTFRVEVFWGTIGIMTLSSFPLAYLPVSAILKRLDRSLE
HHHHHHHHHHHHHHCCHHHEEEEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EVSLSLGKSPVYTFWYAISPQLKPAIGSSILLIALHMLVEFGAVSILNYQTFTTAIFQEY
HHHHHHCCCCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMSFNNSTAALLSAVLMAICILIVFGEIFFRGKQTLYHSGKGVTRPYLVKTLSFGKQCLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHH
FGFFSSIFILSIGVPVIMLIYWLIVGTSLESAGDFSEFLSAFSNSFIISGLGALLTVMCA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
LPLVWAAVRYRSYLTIWIDRLPYLLHAVPGLVIALSLVYFSIHYANDLYQTFFVIIIAYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLYLPMAQTTLRASLEQLSDQIEKVGQSLGRNPFYIFRTLTLPAILPGVAAAFALVFLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
MKELTATLLLTSNDIKTLSIAVWEHTSDAQYAAATPYALMLVLFSGIPVFLLKKYAFK
HHHHHHHHHEECCCCCEEEEEEEECCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MRATEVGLTRSVELLFRPRMAELLSNTMLLMVCVTIGAISLGTFCAFLLERYRFFGKAFF
CCCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAMTLPLCIPAFVSGFTWISLTFRVEVFWGTIGIMTLSSFPLAYLPVSAILKRLDRSLE
HHHHHHHHHHHHHHCCHHHEEEEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EVSLSLGKSPVYTFWYAISPQLKPAIGSSILLIALHMLVEFGAVSILNYQTFTTAIFQEY
HHHHHHCCCCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMSFNNSTAALLSAVLMAICILIVFGEIFFRGKQTLYHSGKGVTRPYLVKTLSFGKQCLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHH
FGFFSSIFILSIGVPVIMLIYWLIVGTSLESAGDFSEFLSAFSNSFIISGLGALLTVMCA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
LPLVWAAVRYRSYLTIWIDRLPYLLHAVPGLVIALSLVYFSIHYANDLYQTFFVIIIAYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLYLPMAQTTLRASLEQLSDQIEKVGQSLGRNPFYIFRTLTLPAILPGVAAAFALVFLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
MKELTATLLLTSNDIKTLSIAVWEHTSDAQYAAATPYALMLVLFSGIPVFLLKKYAFK
HHHHHHHHHEECCCCCEEEEEEEECCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 7927717 [H]