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The map label for this gene is arcB [H]

Identifier: 16273674

GI number: 16273674

Start: 239516

End: 240229

Strand: Reverse

Name: arcB [H]

Synonym: HI0219a

Alternate gene names: 16273674

Gene position: 240229-239516 (Counterclockwise)

Preceding gene: 30995363

Following gene: 30995362

Centisome position: 13.13

GC content: 32.91

Gene sequence:

>714_bases
GTGGAAGATGTTGATCTCAATATTATGGTTGCAAAAACTATTTTAGAAAAACTTGGGCATCATGTTGATGTTGCGACAAA
TGGCAAGCAGGCGATTACTTTATTTGAGAAAAATGTTTATGACATTCTATTGCTCGATATTAAATTACCAGATATGAGTG
GTTTTGAAATTGCCCAATATTTGCGAGAGAACTATGAAAACGGTATTTATGATTTTTTACCGCCAATGATTGCTTTTACC
GCCAATGTTATGCAAAGCGAGCAAGAATATTTAGAAATGGGCATGGATGGCGTATTACGTAAACCCATTTCAATTAAGGA
TTTACACCATTGTCTACAGCAATTTTTTGCGGATGAAAGCGAATCTATTATAGAAATGAATGATGATAATGAGCTTTCAG
AACAGTTTGATTTAGCGCTGATAGAAACACTTGGAAAATCCCAAATTTTAGAAAATTTATCTTTATTCAAACAAACTATG
CCAAATTATCTGGCTCAATTATCAAAAGATAATATGAAAGAAACAGAAGATACCGCCCATAAAATTAAAGGCGCAGCGGC
ATCGGTAGGGTTAAATCATTTACGTCAATTAGCGGATACTTTAGAAAGTGCGGCTAAAAATTCTGATGTTTTTAATTGTG
GAGAATTGATTGATAAAATTGGAAATCTTTGGTTAGAAGATGTGGAGGATTTGCTTAAATTTTGTAAATTTTAA

Upstream 100 bases:

>100_bases
ACGAGGAAAAGGCGCGACTTTCCATCTNACTCTCCACGCTCAGGAAATTTCTGAAAAAGAATCTGTTAAGNAAAATATAC
CATCCTTGAATACTCTTTTA

Downstream 100 bases:

>100_bases
TATTATAAGGTAGTTGTGTAAAGATTATTTACATGTGATTTAAAGATAATAAAGAGGCTTAAAATGGGAAAATCAAATTT
TATTTTAATTAGTAAAACTT

Product: two component signal transduction system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MEDVDLNIMVAKTILEKLGHHVDVATNGKQAITLFEKNVYDILLLDIKLPDMSGFEIAQYLRENYENGIYDFLPPMIAFT
ANVMQSEQEYLEMGMDGVLRKPISIKDLHHCLQQFFADESESIIEMNDDNELSEQFDLALIETLGKSQILENLSLFKQTM
PNYLAQLSKDNMKETEDTAHKIKGAAASVGLNHLRQLADTLESAAKNSDVFNCGELIDKIGNLWLEDVEDLLKFCKF

Sequences:

>Translated_237_residues
MEDVDLNIMVAKTILEKLGHHVDVATNGKQAITLFEKNVYDILLLDIKLPDMSGFEIAQYLRENYENGIYDFLPPMIAFT
ANVMQSEQEYLEMGMDGVLRKPISIKDLHHCLQQFFADESESIIEMNDDNELSEQFDLALIETLGKSQILENLSLFKQTM
PNYLAQLSKDNMKETEDTAHKIKGAAASVGLNHLRQLADTLESAAKNSDVFNCGELIDKIGNLWLEDVEDLLKFCKF
>Mature_237_residues
MEDVDLNIMVAKTILEKLGHHVDVATNGKQAITLFEKNVYDILLLDIKLPDMSGFEIAQYLRENYENGIYDFLPPMIAFT
ANVMQSEQEYLEMGMDGVLRKPISIKDLHHCLQQFFADESESIIEMNDDNELSEQFDLALIETLGKSQILENLSLFKQTM
PNYLAQLSKDNMKETEDTAHKIKGAAASVGLNHLRQLADTLESAAKNSDVFNCGELIDKIGNLWLEDVEDLLKFCKF

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG2198

COG function: function code T; FOG: HPt domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=39.0041493775934, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=24.3362831858407, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=120, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 26899; Mature: 26899

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDVDLNIMVAKTILEKLGHHVDVATNGKQAITLFEKNVYDILLLDIKLPDMSGFEIAQY
CCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCHHEEEEEEEECCCCCHHHHHHH
LRENYENGIYDFLPPMIAFTANVMQSEQEYLEMGMDGVLRKPISIKDLHHCLQQFFADES
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHCCCC
ESIIEMNDDNELSEQFDLALIETLGKSQILENLSLFKQTMPNYLAQLSKDNMKETEDTAH
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KIKGAAASVGLNHLRQLADTLESAAKNSDVFNCGELIDKIGNLWLEDVEDLLKFCKF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEDVDLNIMVAKTILEKLGHHVDVATNGKQAITLFEKNVYDILLLDIKLPDMSGFEIAQY
CCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCHHEEEEEEEECCCCCHHHHHHH
LRENYENGIYDFLPPMIAFTANVMQSEQEYLEMGMDGVLRKPISIKDLHHCLQQFFADES
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHCCCC
ESIIEMNDDNELSEQFDLALIETLGKSQILENLSLFKQTMPNYLAQLSKDNMKETEDTAH
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KIKGAAASVGLNHLRQLADTLESAAKNSDVFNCGELIDKIGNLWLEDVEDLLKFCKF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]