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The map label for this gene is modB

Identifier: 16273579

GI number: 16273579

Start: 1762420

End: 1763109

Strand: Reverse

Name: modB

Synonym: HI1692

Alternate gene names: 16273579

Gene position: 1763109-1762420 (Counterclockwise)

Preceding gene: 16273580

Following gene: 16273578

Centisome position: 96.34

GC content: 42.9

Gene sequence:

>690_bases
ATGGAAATCTCAGCAATTAATTTAAGCCTGAGTGTTGCAGTCAGTTCCATGCTTTGGAGTTTGCCGTTAGCCATTTTTGT
GGCGTGGCTCTTAGCGCGCAAAAACTTCTATGGTAAATCCCTGATTACTGGCGTAATTCATTTGCCTTTAGTGTTGCCAC
CTGTGGTTATCGGTTATCTATTGCTTGTGGCAATGGGGCGCAATGGTTTCATTGGCAAGTATTTATATCAGTGGTTTGGC
TTATCTTTTGGCTTTAGTTGGAAGGGGGCGGTGCTTTCCTCTGCCGTGGTTGCCTTTCCATTGGTTGTTCGCGCGATTCG
ACTTTCTTTAGAAAATATTGATATTAAATTGGAGCAAGCGGCGCAAACATTGGGTGCTTCCGCTTGGCGTGTATTTTTTA
CAATAACCTTGCCGCTTTCTTTACCGGGGGTTTTAGCTGGACTCGTGCTTGGTTTTGCTCGATCATTAGGAGAATTTGGC
GCGACCATTACGTTTGTATCGAACATTGCAGGCGAAACTCAAACGATTCCCCTTGCGATGTATTCTTTTATTCAAACACC
AGGTGCAGAAGAACAAACTGCTCGCTTATGTTTATTTGCTATCATTCTTTCATTGATTTCTTTGCTATTGTCAGAGTGGT
TGAGCAAGCGGATGCAGAAAAAATTAGGACAAGGAAATGTTGCAGATTAA

Upstream 100 bases:

>100_bases
AATGTGGGATATTCCCATAAACAAGGGATTTAAAGAGAGGCTATTTAGATAAGGATTCATTTTGCTTACCCAATTTTTTT
CATTTTTCAATCTGACGCCA

Downstream 100 bases:

>100_bases
TGTGAAAAAACAGCTCGGGCAACTTGCCTTGCAAGCGAATATACAAGTGCCAGATCAAGGTGTAACCGCTATTTTCGGTT
TGTCTGGCTCAGGCAAAACA

Product: molybdate ABC transporter permease

Products: ADP; phosphate; MoO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MEISAINLSLSVAVSSMLWSLPLAIFVAWLLARKNFYGKSLITGVIHLPLVLPPVVIGYLLLVAMGRNGFIGKYLYQWFG
LSFGFSWKGAVLSSAVVAFPLVVRAIRLSLENIDIKLEQAAQTLGASAWRVFFTITLPLSLPGVLAGLVLGFARSLGEFG
ATITFVSNIAGETQTIPLAMYSFIQTPGAEEQTARLCLFAIILSLISLLLSEWLSKRMQKKLGQGNVAD

Sequences:

>Translated_229_residues
MEISAINLSLSVAVSSMLWSLPLAIFVAWLLARKNFYGKSLITGVIHLPLVLPPVVIGYLLLVAMGRNGFIGKYLYQWFG
LSFGFSWKGAVLSSAVVAFPLVVRAIRLSLENIDIKLEQAAQTLGASAWRVFFTITLPLSLPGVLAGLVLGFARSLGEFG
ATITFVSNIAGETQTIPLAMYSFIQTPGAEEQTARLCLFAIILSLISLLLSEWLSKRMQKKLGQGNVAD
>Mature_229_residues
MEISAINLSLSVAVSSMLWSLPLAIFVAWLLARKNFYGKSLITGVIHLPLVLPPVVIGYLLLVAMGRNGFIGKYLYQWFG
LSFGFSWKGAVLSSAVVAFPLVVRAIRLSLENIDIKLEQAAQTLGASAWRVFFTITLPLSLPGVLAGLVLGFARSLGEFG
ATITFVSNIAGETQTIPLAMYSFIQTPGAEEQTARLCLFAIILSLISLLLSEWLSKRMQKKLGQGNVAD

Specific function: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1786980, Length=223, Percent_Identity=65.9192825112108, Blast_Score=274, Evalue=3e-75,
Organism=Escherichia coli, GI1788764, Length=183, Percent_Identity=34.4262295081967, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082099, Length=225, Percent_Identity=34.6666666666667, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787368, Length=227, Percent_Identity=28.1938325991189, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MODB_HAEIN (P45322)

Other databases:

- EMBL:   L42023
- PIR:   A64137
- RefSeq:   NP_439834.1
- ProteinModelPortal:   P45322
- SMR:   P45322
- GeneID:   949953
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1692
- TIGR:   HI_1692
- HOGENOM:   HBG685300
- OMA:   LAWRGIL
- ProtClustDB:   PRK09421
- BioCyc:   HINF71421:HI_1692-MONOMER
- InterPro:   IPR000515
- InterPro:   IPR011867
- TIGRFAMs:   TIGR02141

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 24823; Mature: 24823

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xedf91f8)-; HASH(0xcf870e0)-; HASH(0xe926d7c)-; HASH(0xed813c8)-; HASH(0xecb2638)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEISAINLSLSVAVSSMLWSLPLAIFVAWLLARKNFYGKSLITGVIHLPLVLPPVVIGYL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLVAMGRNGFIGKYLYQWFGLSFGFSWKGAVLSSAVVAFPLVVRAIRLSLENIDIKLEQA
HHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AQTLGASAWRVFFTITLPLSLPGVLAGLVLGFARSLGEFGATITFVSNIAGETQTIPLAM
HHHHCCHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YSFIQTPGAEEQTARLCLFAIILSLISLLLSEWLSKRMQKKLGQGNVAD
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure
MEISAINLSLSVAVSSMLWSLPLAIFVAWLLARKNFYGKSLITGVIHLPLVLPPVVIGYL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLVAMGRNGFIGKYLYQWFGLSFGFSWKGAVLSSAVVAFPLVVRAIRLSLENIDIKLEQA
HHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AQTLGASAWRVFFTITLPLSLPGVLAGLVLGFARSLGEFGATITFVSNIAGETQTIPLAM
HHHHCCHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YSFIQTPGAEEQTARLCLFAIILSLISLLLSEWLSKRMQKKLGQGNVAD
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; MoO42- [Periplasm]; H2O [C]

Specific reaction: ATP + MoO42- [Periplasm] + H2O = ADP + phosphate + MoO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800