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The map label for this gene is pepN

Identifier: 16273504

GI number: 16273504

Start: 1680195

End: 1682804

Strand: Reverse

Name: pepN

Synonym: HI1614

Alternate gene names: 16273504

Gene position: 1682804-1680195 (Counterclockwise)

Preceding gene: 30995461

Following gene: 16273502

Centisome position: 91.95

GC content: 38.16

Gene sequence:

>2610_bases
ATGTTAGCCAAAGCAAAATATAGAAAAGATTACAAACAACCAGATTTTACGGTCACAGATATTTATTTAGATTTTCAACT
TGATCCTAAACATACTGTGGTAACCGCAATCACAAAATTCCAACGCTTAAATAATGAAGCGACTTCTTTATGTTTAGACG
GGCATAGCTTCCAGTTTTCTTCTATTAAATTTAATGGCGAGCCATTTTCTGATTATCAACAAGATGGCGAGAGTTTAACG
CTCGATTTAAAAGACAAAAGTGCGGATGAATTTGAGATTGAAATTGTGACGTTCCTTGTGCCAGCCGAAAATACGTCATT
ACAAGGGCTATATCAGTCTGGCGAGGGTATTTGTACGCAATGTGAGGCGGAAGGTTTCCGTCAAATCACTTATATGCTTG
ATCGTCCTGATGTGCTGGCGCGTTATATAACCAAAATTACGGCAGATAAAACCAAATATCCATTCTTACTGTCGAATGGT
AATCGCATTGCAAGTGGCGAATTAGAAGATGGTCGCCATTGGGTGGAATGGAATGATCCTTTCCCAAAACCAAGCTATTT
ATTTGCTTTAGTGGCGGGAGATTTTGATTTATTACAAGATAAATTTATTACTAAAAGTGGTCGTGAAGTGGCTTTAGAGC
TTTATGTGGATCGCGGTAATCTTAACCGTGCAACTTGGGCAATGGAAAGTCTGAAAAAAGCGATGAAATGGGATGAAGAT
CGCTTTAATTTAGAATATGACCTAGATATTTATATGATCGTTGCCGTCGATTTCTTCAATATGGGCGCAATGGAAAATAA
AGGGTTAAATATCTTTAATTCCAAATTTGTGTTGGCAAATCCACAAACGGCAACCGATGATGATTATCTTGCCATTGAAA
GTGTGATTGCTCACGAATATTTTCATAACTGGACAGGAAACCGTGTAACCTGCCGAGATTGGTTCCAATTAAGTTTGAAA
GAGGGTTTAACGGTTTTCCGTGATCAAGAATTTTCTTCAGATACAGGTTCGCGTGCCGTGAATCGCATTAATAATGTGAA
ATTTTTACGCACCGTGCAATTTGCCGAAGATGCAAGCCCAATGTCGCACCCAATTCGCCCTGAAAAAGTGATTGAAATGA
ATAACTTTTACACGGTGACAGTATATGAAAAAGGGGCAGAAGTCATTCGTATGTTGCACACCTTATTAGGTGAACAAGGT
TTCCAAAAAGGCATGCAACTTTATATTGCTGAAAACGATGGCAAAGCGGCAACCTGTGAAGACTTTGTTTCTGCGATGGA
ACGTGCAAATAACCTCGATTTAAATCAATTCCGCCGTTGGTATAGCCAATCGGGTACCCCAGAATTATTGATTAGTGATG
CTTATGACGAAAAAACGCATACTTATCGTTTAACGGTTTCACAATCCACACCGCCAACCGCAGATCAAATGGAAAAAGTG
AATTTACATATTCCATTAAAAGTGGCGCTTTATGATGCGAACGGCACGAAACAAATGCTACAACATAATGGCGAATTGTT
GAGTGATGTATTAAATGTCACTGAAAAAGACCAAGTCTTTGAGTTTCATGGCATTTATGGTCGCCCAATTCCCGCATTGC
TATGTGATTTTTCTGCGCCAGTAAAACTGGATTATGATTATAAAACGGAGCAGTTATTAGGCTTGCTTAAATTTGCAGAT
AATCAATTTATCCGTTGGGATGCGGCTCAAATGTTATTTGCGCAAGAATTGCGTCGTAATGTTGTGCGTTTCCAACAAGG
CGAGGCTTTAGAAATTTCGCCTGAAATTTTGACCGCACTTTCTTATGTTCTGAACCATTATGAGAAAGATATTGAATTGG
CAACCTTAATTCTCACACTGCCGAAAGAAATGGAGTTTGCAGAAAGTTTTAAAACCATCGATCCTGATGGTATTTCAGCC
GCAAGAGCATTTATGCAAGCTCAAATTGCAGAATCTTTAAAAGATGATTTCTTGCGTGTTTATACCCATATTCGTCTTAA
TGATTATCAAGTTACGCAACAAGACATCGCCTTACGTGTAATGCGTAATCTTTGTTTAACTTATTTGGCTTACACCAATT
TGGGCAATAACCTAGTGCAAAAACACTACAATAATGCGAATAATATGACAGATACATTGGCGGCATTAAGTGTTGCAACT
AAAGCTGCATTACTTTGCAGAGATGTGTTATTAGCTGATTTTGAACAAAAATGGCAACACGATGGATTAGTCATGGATAA
ATGGTTTGCATTACAAGCCACTCGCCCAGATGATAATGTGTTGGAAATTATTCAGTTATTAATGGATCACCCAAGTTTTA
ATTTTAATAATCCAAACCGTTTACGTTCATTAGTAGGTAGCTTTGCAAATCACAACTTAAAAGCATTCCATAATGTAAGT
GGATCAGGCTATCGTTTCTTAACGGATGTGTTAATCCGTTTAAATGAAAGTAATCCGCAAGTGGCTGCGCGTTTAATCGA
GCCATTAATTCGTTTTTCTCGCTTTGATGCCCAACGCCAAACGCTGATGAAACGTGCTTTAGAACGCCTAAGCGTTGTAG
AAAATCTTTCAAAAGATTTATTTGAAAAAATTGAGAAAGCGTTGCAGTAA

Upstream 100 bases:

>100_bases
AGGCAAACGTTTGCTAAATGGCTTTTATAGGAAAATACCATTGCAACTTTAAGGATAAAATTTTATCCTAAGCACAATTT
TTATAAGAATAGGTCAAATT

Downstream 100 bases:

>100_bases
CACTTGATGATGTGAGAATAGGCTTTATGCCCATTCTCACTTTATTCAATTGCTTAATATTTTTAAATGAACTAGAAATT
TTTTGACTGCAAATAATTTT

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase

Number of amino acids: Translated: 869; Mature: 869

Protein sequence:

>869_residues
MLAKAKYRKDYKQPDFTVTDIYLDFQLDPKHTVVTAITKFQRLNNEATSLCLDGHSFQFSSIKFNGEPFSDYQQDGESLT
LDLKDKSADEFEIEIVTFLVPAENTSLQGLYQSGEGICTQCEAEGFRQITYMLDRPDVLARYITKITADKTKYPFLLSNG
NRIASGELEDGRHWVEWNDPFPKPSYLFALVAGDFDLLQDKFITKSGREVALELYVDRGNLNRATWAMESLKKAMKWDED
RFNLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKFVLANPQTATDDDYLAIESVIAHEYFHNWTGNRVTCRDWFQLSLK
EGLTVFRDQEFSSDTGSRAVNRINNVKFLRTVQFAEDASPMSHPIRPEKVIEMNNFYTVTVYEKGAEVIRMLHTLLGEQG
FQKGMQLYIAENDGKAATCEDFVSAMERANNLDLNQFRRWYSQSGTPELLISDAYDEKTHTYRLTVSQSTPPTADQMEKV
NLHIPLKVALYDANGTKQMLQHNGELLSDVLNVTEKDQVFEFHGIYGRPIPALLCDFSAPVKLDYDYKTEQLLGLLKFAD
NQFIRWDAAQMLFAQELRRNVVRFQQGEALEISPEILTALSYVLNHYEKDIELATLILTLPKEMEFAESFKTIDPDGISA
ARAFMQAQIAESLKDDFLRVYTHIRLNDYQVTQQDIALRVMRNLCLTYLAYTNLGNNLVQKHYNNANNMTDTLAALSVAT
KAALLCRDVLLADFEQKWQHDGLVMDKWFALQATRPDDNVLEIIQLLMDHPSFNFNNPNRLRSLVGSFANHNLKAFHNVS
GSGYRFLTDVLIRLNESNPQVAARLIEPLIRFSRFDAQRQTLMKRALERLSVVENLSKDLFEKIEKALQ

Sequences:

>Translated_869_residues
MLAKAKYRKDYKQPDFTVTDIYLDFQLDPKHTVVTAITKFQRLNNEATSLCLDGHSFQFSSIKFNGEPFSDYQQDGESLT
LDLKDKSADEFEIEIVTFLVPAENTSLQGLYQSGEGICTQCEAEGFRQITYMLDRPDVLARYITKITADKTKYPFLLSNG
NRIASGELEDGRHWVEWNDPFPKPSYLFALVAGDFDLLQDKFITKSGREVALELYVDRGNLNRATWAMESLKKAMKWDED
RFNLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKFVLANPQTATDDDYLAIESVIAHEYFHNWTGNRVTCRDWFQLSLK
EGLTVFRDQEFSSDTGSRAVNRINNVKFLRTVQFAEDASPMSHPIRPEKVIEMNNFYTVTVYEKGAEVIRMLHTLLGEQG
FQKGMQLYIAENDGKAATCEDFVSAMERANNLDLNQFRRWYSQSGTPELLISDAYDEKTHTYRLTVSQSTPPTADQMEKV
NLHIPLKVALYDANGTKQMLQHNGELLSDVLNVTEKDQVFEFHGIYGRPIPALLCDFSAPVKLDYDYKTEQLLGLLKFAD
NQFIRWDAAQMLFAQELRRNVVRFQQGEALEISPEILTALSYVLNHYEKDIELATLILTLPKEMEFAESFKTIDPDGISA
ARAFMQAQIAESLKDDFLRVYTHIRLNDYQVTQQDIALRVMRNLCLTYLAYTNLGNNLVQKHYNNANNMTDTLAALSVAT
KAALLCRDVLLADFEQKWQHDGLVMDKWFALQATRPDDNVLEIIQLLMDHPSFNFNNPNRLRSLVGSFANHNLKAFHNVS
GSGYRFLTDVLIRLNESNPQVAARLIEPLIRFSRFDAQRQTLMKRALERLSVVENLSKDLFEKIEKALQ
>Mature_869_residues
MLAKAKYRKDYKQPDFTVTDIYLDFQLDPKHTVVTAITKFQRLNNEATSLCLDGHSFQFSSIKFNGEPFSDYQQDGESLT
LDLKDKSADEFEIEIVTFLVPAENTSLQGLYQSGEGICTQCEAEGFRQITYMLDRPDVLARYITKITADKTKYPFLLSNG
NRIASGELEDGRHWVEWNDPFPKPSYLFALVAGDFDLLQDKFITKSGREVALELYVDRGNLNRATWAMESLKKAMKWDED
RFNLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKFVLANPQTATDDDYLAIESVIAHEYFHNWTGNRVTCRDWFQLSLK
EGLTVFRDQEFSSDTGSRAVNRINNVKFLRTVQFAEDASPMSHPIRPEKVIEMNNFYTVTVYEKGAEVIRMLHTLLGEQG
FQKGMQLYIAENDGKAATCEDFVSAMERANNLDLNQFRRWYSQSGTPELLISDAYDEKTHTYRLTVSQSTPPTADQMEKV
NLHIPLKVALYDANGTKQMLQHNGELLSDVLNVTEKDQVFEFHGIYGRPIPALLCDFSAPVKLDYDYKTEQLLGLLKFAD
NQFIRWDAAQMLFAQELRRNVVRFQQGEALEISPEILTALSYVLNHYEKDIELATLILTLPKEMEFAESFKTIDPDGISA
ARAFMQAQIAESLKDDFLRVYTHIRLNDYQVTQQDIALRVMRNLCLTYLAYTNLGNNLVQKHYNNANNMTDTLAALSVAT
KAALLCRDVLLADFEQKWQHDGLVMDKWFALQATRPDDNVLEIIQLLMDHPSFNFNNPNRLRSLVGSFANHNLKAFHNVS
GSGYRFLTDVLIRLNESNPQVAARLIEPLIRFSRFDAQRQTLMKRALERLSVVENLSKDLFEKIEKALQ

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family

Homologues:

Organism=Homo sapiens, GI158937236, Length=420, Percent_Identity=27.8571428571429, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI310133497, Length=373, Percent_Identity=28.686327077748, Blast_Score=113, Evalue=8e-25,
Organism=Homo sapiens, GI310123622, Length=370, Percent_Identity=28.3783783783784, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI132814467, Length=368, Percent_Identity=28.804347826087, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI61742777, Length=410, Percent_Identity=25.8536585365854, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI61742775, Length=410, Percent_Identity=25.8536585365854, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI194306629, Length=425, Percent_Identity=26.1176470588235, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI11641261, Length=425, Percent_Identity=26.1176470588235, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI94818901, Length=324, Percent_Identity=27.1604938271605, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI94818891, Length=324, Percent_Identity=27.1604938271605, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI194239713, Length=349, Percent_Identity=26.3610315186246, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI7019561, Length=261, Percent_Identity=29.1187739463602, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI157266300, Length=354, Percent_Identity=25.1412429378531, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI4505029, Length=452, Percent_Identity=23.4513274336283, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI1787163, Length=867, Percent_Identity=60.6689734717416, Blast_Score=1070, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989071, Length=417, Percent_Identity=27.3381294964029, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71989076, Length=423, Percent_Identity=27.4231678486998, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI115533278, Length=423, Percent_Identity=26.241134751773, Blast_Score=102, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI115533276, Length=423, Percent_Identity=26.241134751773, Blast_Score=102, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17569221, Length=374, Percent_Identity=24.0641711229947, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17569225, Length=355, Percent_Identity=25.0704225352113, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565628, Length=373, Percent_Identity=25.4691689008043, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193206928, Length=363, Percent_Identity=25.8953168044077, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193206926, Length=363, Percent_Identity=25.8953168044077, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI133903840, Length=346, Percent_Identity=24.8554913294798, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71984353, Length=439, Percent_Identity=24.6013667425968, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71984339, Length=439, Percent_Identity=24.1457858769932, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71990873, Length=183, Percent_Identity=28.9617486338798, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321837, Length=425, Percent_Identity=25.6470588235294, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI9755335, Length=384, Percent_Identity=25.2604166666667, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324283, Length=440, Percent_Identity=22.7272727272727, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24655257, Length=453, Percent_Identity=26.7108167770419, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24655252, Length=453, Percent_Identity=26.7108167770419, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655274, Length=453, Percent_Identity=26.7108167770419, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655260, Length=453, Percent_Identity=26.7108167770419, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655265, Length=453, Percent_Identity=26.7108167770419, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655268, Length=453, Percent_Identity=26.7108167770419, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646516, Length=380, Percent_Identity=28.1578947368421, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646518, Length=380, Percent_Identity=28.1578947368421, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646514, Length=360, Percent_Identity=28.6111111111111, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI21358341, Length=395, Percent_Identity=27.5949367088608, Blast_Score=106, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24651025, Length=393, Percent_Identity=26.4631043256997, Blast_Score=103, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24651023, Length=393, Percent_Identity=26.4631043256997, Blast_Score=103, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24651021, Length=393, Percent_Identity=26.4631043256997, Blast_Score=103, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24651016, Length=239, Percent_Identity=28.0334728033473, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646512, Length=352, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646510, Length=352, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221379089, Length=358, Percent_Identity=27.0949720670391, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24650973, Length=373, Percent_Identity=25.201072386059, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550850, Length=373, Percent_Identity=25.201072386059, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28571901, Length=359, Percent_Identity=24.5125348189415, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI161078673, Length=359, Percent_Identity=24.5125348189415, Blast_Score=90, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24648786, Length=348, Percent_Identity=24.4252873563218, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571792, Length=305, Percent_Identity=25.2459016393443, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648790, Length=202, Percent_Identity=27.2277227722772, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330574, Length=321, Percent_Identity=25.2336448598131, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AMPN_HAEIN (P45274)

Other databases:

- EMBL:   L42023
- EMBL:   Z33502
- EMBL:   U58657
- PIR:   F64132
- RefSeq:   NP_439756.1
- ProteinModelPortal:   P45274
- SMR:   P45274
- MEROPS:   M01.005
- GeneID:   950613
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1614
- NMPDR:   fig|71421.1.peg.1530
- TIGR:   HI_1614
- HOGENOM:   HBG289207
- OMA:   DIFMIVA
- ProtClustDB:   PRK14015
- BioCyc:   HINF71421:HI_1614-MONOMER
- BRENDA:   3.4.11.2
- GO:   GO:0006508
- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779
- PANTHER:   PTHR11533:SF8
- PANTHER:   PTHR11533
- PRINTS:   PR00756
- TIGRFAMs:   TIGR02414

Pfam domain/function: PF01433 Peptidase_M1

EC number: =3.4.11.2

Molecular weight: Translated: 99787; Mature: 99787

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 299-299 ACT_SITE 382-382

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKAKYRKDYKQPDFTVTDIYLDFQLDPKHTVVTAITKFQRLNNEATSLCLDGHSFQFS
CCCCCCHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHCCHHHEEEECCCCEEEE
SIKFNGEPFSDYQQDGESLTLDLKDKSADEFEIEIVTFLVPAENTSLQGLYQSGEGICTQ
EEEECCCCCHHHHCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHCCCCCEEE
CEAEGFRQITYMLDRPDVLARYITKITADKTKYPFLLSNGNRIASGELEDGRHWVEWNDP
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCEEECCCCCCCCEEEECCCC
FPKPSYLFALVAGDFDLLQDKFITKSGREVALELYVDRGNLNRATWAMESLKKAMKWDED
CCCCCCEEEEECCCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
RFNLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKFVLANPQTATDDDYLAIESVIAHEY
CCCEEECCCEEEEEEEHHHCCCCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHHHH
FHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDTGSRAVNRINNVKFLRTVQFAEDASP
HHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCHHHEEEEHHHHCCCC
MSHPIRPEKVIEMNNFYTVTVYEKGAEVIRMLHTLLGEQGFQKGMQLYIAENDGKAATCE
CCCCCCCHHEEEECCEEEEEEECCCHHHHHHHHHHHCHHHHHCCEEEEEEECCCCCCCHH
DFVSAMERANNLDLNQFRRWYSQSGTPELLISDAYDEKTHTYRLTVSQSTPPTADQMEKV
HHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCHHHHHEE
NLHIPLKVALYDANGTKQMLQHNGELLSDVLNVTEKDQVFEFHGIYGRPIPALLCDFSAP
EEEEEEEEEEECCCCHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCC
VKLDYDYKTEQLLGLLKFADNQFIRWDAAQMLFAQELRRNVVRFQQGEALEISPEILTAL
EEEECCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
SYVLNHYEKDIELATLILTLPKEMEFAESFKTIDPDGISAARAFMQAQIAESLKDDFLRV
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YTHIRLNDYQVTQQDIALRVMRNLCLTYLAYTNLGNNLVQKHYNNANNMTDTLAALSVAT
HHHEEECCEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHH
KAALLCRDVLLADFEQKWQHDGLVMDKWFALQATRPDDNVLEIIQLLMDHPSFNFNNPNR
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHH
LRSLVGSFANHNLKAFHNVSGSGYRFLTDVLIRLNESNPQVAARLIEPLIRFSRFDAQRQ
HHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHH
TLMKRALERLSVVENLSKDLFEKIEKALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAKAKYRKDYKQPDFTVTDIYLDFQLDPKHTVVTAITKFQRLNNEATSLCLDGHSFQFS
CCCCCCHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHCCHHHEEEECCCCEEEE
SIKFNGEPFSDYQQDGESLTLDLKDKSADEFEIEIVTFLVPAENTSLQGLYQSGEGICTQ
EEEECCCCCHHHHCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHCCCCCEEE
CEAEGFRQITYMLDRPDVLARYITKITADKTKYPFLLSNGNRIASGELEDGRHWVEWNDP
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCEEECCCCCCCCEEEECCCC
FPKPSYLFALVAGDFDLLQDKFITKSGREVALELYVDRGNLNRATWAMESLKKAMKWDED
CCCCCCEEEEECCCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
RFNLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKFVLANPQTATDDDYLAIESVIAHEY
CCCEEECCCEEEEEEEHHHCCCCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHHHH
FHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDTGSRAVNRINNVKFLRTVQFAEDASP
HHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCHHHEEEEHHHHCCCC
MSHPIRPEKVIEMNNFYTVTVYEKGAEVIRMLHTLLGEQGFQKGMQLYIAENDGKAATCE
CCCCCCCHHEEEECCEEEEEEECCCHHHHHHHHHHHCHHHHHCCEEEEEEECCCCCCCHH
DFVSAMERANNLDLNQFRRWYSQSGTPELLISDAYDEKTHTYRLTVSQSTPPTADQMEKV
HHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCHHHHHEE
NLHIPLKVALYDANGTKQMLQHNGELLSDVLNVTEKDQVFEFHGIYGRPIPALLCDFSAP
EEEEEEEEEEECCCCHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCC
VKLDYDYKTEQLLGLLKFADNQFIRWDAAQMLFAQELRRNVVRFQQGEALEISPEILTAL
EEEECCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
SYVLNHYEKDIELATLILTLPKEMEFAESFKTIDPDGISAARAFMQAQIAESLKDDFLRV
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YTHIRLNDYQVTQQDIALRVMRNLCLTYLAYTNLGNNLVQKHYNNANNMTDTLAALSVAT
HHHEEECCEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHH
KAALLCRDVLLADFEQKWQHDGLVMDKWFALQATRPDDNVLEIIQLLMDHPSFNFNNPNR
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHH
LRSLVGSFANHNLKAFHNVSGSGYRFLTDVLIRLNESNPQVAARLIEPLIRFSRFDAQRQ
HHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHH
TLMKRALERLSVVENLSKDLFEKIEKALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 7927773; 7997179