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The map label for this gene is ipk [H]

Identifier: 16273498

GI number: 16273498

Start: 1673986

End: 1674927

Strand: Direct

Name: ipk [H]

Synonym: HI1608

Alternate gene names: 16273498

Gene position: 1673986-1674927 (Clockwise)

Preceding gene: 16273497

Following gene: 16273499

Centisome position: 91.47

GC content: 37.26

Gene sequence:

>942_bases
ATGAAATCACATCAATTTTCTACCGCACTTTGCCAAAATACAACAGAATCAAATGGGCAGCCATTACGCTTCCCTAGCCC
AGCCAAACTGAATTTATTTCTTTATATCAATGGAAAATTTCCGAACGGCTATCATGAATTACAAACGCTTTTCCAATTTT
TAGATTTTGGCGATTGGTTAGACATTAGTATTCGGGAACAAGATAATCAAATTGTTTTAACGCCAGAAATTCCAAATCTA
AAAACGGAAAATAATCTAATTTATCGAGCCGCAAAACTTTTACAAGAAAAAGCCAATATTCAATTGGGTGCAAATATTCA
TTTAGATAAAATTCTTCCAATGGGAGGCGGTGTTGGTGGTGGTTCATCCAATGCAGCAACCGCATTAGTCTCTTTAAATT
ATTTATGGCAAGCCAATTTATCCATTGATGAACTAGCAAAATTGGGATTAACATTAGGCGCAGATGTGCCAATATTTGTA
CATGGACACGCAGCTTTTGCTGAAGGCGTCGGGGAAAAAATCACTTATTGTGAACCTGCCGAAAAATGGTTTGTTATATT
AAAACCCGATGATTCAATATCGACGGCTGTGATATTTCAAGATCCAAATTTACCACGTAATACACCGAAAAAATCCCTCG
CACAACTTTTGAGTGAACCTTATAAAAACGATTGCGAAAAAGTTGTGATAAATCATTATTCAAACGTTGAAAAAGCGTTA
AACTGGTTGCTACAATATGCGCCGGCAAGATTAACAGGAACGGGAGCCTGTGTTTTTGCTGAATTTGATCATGAAGCAGA
AGCGCAAGCGGTATTTAGACAAAAACCAGAAGCATTTTTTGGTTTCGTCGCTAAAGGACTCAATGTGTCTCCCTTGCACG
CAATGTTGAAGCAGCTATCATCAACTCATACTCATAGACAATCTAAACCTGAGGTTTTATAA

Upstream 100 bases:

>100_bases
CAAATAATTCGATGCCTGAAAATATTTTGCTGAAAAATGACAGCACAAAACAAACCTTAAAAATTCGCGTAGACGAGTGG
ATTTACTAATGAATACATTA

Downstream 100 bases:

>100_bases
AATGCCTGACATTAAACTCTTCGCGGGTAATGCTACACCTGAACTTGCAAAACGTATTTCTGAACGTTTATATATTTCAC
TAGGCGATGCAACAGTCGCT

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKSHQFSTALCQNTTESNGQPLRFPSPAKLNLFLYINGKFPNGYHELQTLFQFLDFGDWLDISIREQDNQIVLTPEIPNL
KTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGGGVGGGSSNAATALVSLNYLWQANLSIDELAKLGLTLGADVPIFV
HGHAAFAEGVGEKITYCEPAEKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLAQLLSEPYKNDCEKVVINHYSNVEKAL
NWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFVAKGLNVSPLHAMLKQLSSTHTHRQSKPEVL

Sequences:

>Translated_313_residues
MKSHQFSTALCQNTTESNGQPLRFPSPAKLNLFLYINGKFPNGYHELQTLFQFLDFGDWLDISIREQDNQIVLTPEIPNL
KTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGGGVGGGSSNAATALVSLNYLWQANLSIDELAKLGLTLGADVPIFV
HGHAAFAEGVGEKITYCEPAEKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLAQLLSEPYKNDCEKVVINHYSNVEKAL
NWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFVAKGLNVSPLHAMLKQLSSTHTHRQSKPEVL
>Mature_313_residues
MKSHQFSTALCQNTTESNGQPLRFPSPAKLNLFLYINGKFPNGYHELQTLFQFLDFGDWLDISIREQDNQIVLTPEIPNL
KTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGGGVGGGSSNAATALVSLNYLWQANLSIDELAKLGLTLGADVPIFV
HGHAAFAEGVGEKITYCEPAEKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLAQLLSEPYKNDCEKVVINHYSNVEKAL
NWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFVAKGLNVSPLHAMLKQLSSTHTHRQSKPEVL

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=281, Percent_Identity=60.1423487544484, Blast_Score=323, Evalue=7e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 34658; Mature: 34658

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHQFSTALCQNTTESNGQPLRFPSPAKLNLFLYINGKFPNGYHELQTLFQFLDFGDWL
CCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEE
DISIREQDNQIVLTPEIPNLKTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGGGVGG
EEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEECCCEEEHHEEECCCCCCC
GSSNAATALVSLNYLWQANLSIDELAKLGLTLGADVPIFVHGHAAFAEGVGEKITYCEPA
CCCCHHEEEEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCCEEECCC
EKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLAQLLSEPYKNDCEKVVINHYSNVEKAL
CCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHH
NWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFVAKGLNVSPLHAMLKQLS
HHHHHHCCCEEECCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHH
STHTHRQSKPEVL
HHHHCCCCCCCCC
>Mature Secondary Structure
MKSHQFSTALCQNTTESNGQPLRFPSPAKLNLFLYINGKFPNGYHELQTLFQFLDFGDWL
CCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEE
DISIREQDNQIVLTPEIPNLKTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGGGVGG
EEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEECCCEEEHHEEECCCCCCC
GSSNAATALVSLNYLWQANLSIDELAKLGLTLGADVPIFVHGHAAFAEGVGEKITYCEPA
CCCCHHEEEEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCCEEECCC
EKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLAQLLSEPYKNDCEKVVINHYSNVEKAL
CCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHH
NWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFVAKGLNVSPLHAMLKQLS
HHHHHHCCCEEECCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHH
STHTHRQSKPEVL
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA