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The map label for this gene is modD

Identifier: 16273377

GI number: 16273377

Start: 1557919

End: 1558764

Strand: Reverse

Name: modD

Synonym: HI1473

Alternate gene names: 16273377

Gene position: 1558764-1557919 (Counterclockwise)

Preceding gene: 16273378

Following gene: 16273376

Centisome position: 85.17

GC content: 37.23

Gene sequence:

>846_bases
ATGATTTATTTTTCAGATAAAGAATTGGATGATTTATTGCTTGAGGACATTTATCGTGGTGATTTAACCACTCATGCCCT
TAGTATTGAAAATATTCCGGCAAAAATTCTGTTTAAGCGTAAAAATGCAGGGGTTGTGGCGGGTGTTTCTGTTGCGGAAA
AATTATTAAAAAAACTGGATATTCAACCGCACTTATATGTAAAAGAAGGGGAGTGGGTTGAATCAGGTGCTTTGTTGATC
AGTGCGGAAGGAATGTCTGAACAATTACATCAAGCTTGGAAAGTGGTGCAATTGGTGCTTGAATGGTCATGTGGGGTTGC
TCAATATACTGCAGAAATGATTGCCAATGCCAAATCGGTTAATCCAACTGCTGTTGTGGCTTGCACGCGTAAAAGTATTC
CTAATACGCGTAAACTTGCGACGAATGCTGTATTAGCCGCTGGTGGGCATATTCATCGACAAGGCGTTAGCGAAACTCTT
TTGGTTTTTACTAATCATCGAAACTTACTTTCTGATCCAAATGATTGGACGAAAATTGTGGATAGATTACGTCAAGAAGC
ACCTGAAAATAAAATTACTTTAGAAGCAGATAATTATGCTCAATTTGAGCAAATGTATATGGCTGAACCCGACATTATTC
AACTTGATAAATGGTTATTGGAGGATGTGAAAAAGGCTTTAGATCTACTTCAATCAAAACAGAAAGATATTCTGCTTTCT
GTCGCTGGAGGAGTAAATAAAAATAATGTATCAGATTACGCCAAATTGGGTATTCGTTTATTTATCACTTCTGCACCTTA
TTATGTACCGCCAGAAGATATAAAGGTGGTGATTGAAAAGATATGA

Upstream 100 bases:

>100_bases
AATTACAACAATTTTAGTAACGCATGAGCCAAAAGAAGCCGAGTATTTTTCAGGTAAGCAGATTCAGTTATATCAGGGTC
AATTAATTTAAGGAGTTACG

Downstream 100 bases:

>100_bases
GTACATAGTTTATCATTATATAAATATGTGTATAATGATATTTTCTTACTTAAAATAAGGATGTGCGATGAAACTTAAAT
CATTGTTAATTGCCTGCTTG

Product: molybdenum transport protein ModD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MIYFSDKELDDLLLEDIYRGDLTTHALSIENIPAKILFKRKNAGVVAGVSVAEKLLKKLDIQPHLYVKEGEWVESGALLI
SAEGMSEQLHQAWKVVQLVLEWSCGVAQYTAEMIANAKSVNPTAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGVSETL
LVFTNHRNLLSDPNDWTKIVDRLRQEAPENKITLEADNYAQFEQMYMAEPDIIQLDKWLLEDVKKALDLLQSKQKDILLS
VAGGVNKNNVSDYAKLGIRLFITSAPYYVPPEDIKVVIEKI

Sequences:

>Translated_281_residues
MIYFSDKELDDLLLEDIYRGDLTTHALSIENIPAKILFKRKNAGVVAGVSVAEKLLKKLDIQPHLYVKEGEWVESGALLI
SAEGMSEQLHQAWKVVQLVLEWSCGVAQYTAEMIANAKSVNPTAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGVSETL
LVFTNHRNLLSDPNDWTKIVDRLRQEAPENKITLEADNYAQFEQMYMAEPDIIQLDKWLLEDVKKALDLLQSKQKDILLS
VAGGVNKNNVSDYAKLGIRLFITSAPYYVPPEDIKVVIEKI
>Mature_281_residues
MIYFSDKELDDLLLEDIYRGDLTTHALSIENIPAKILFKRKNAGVVAGVSVAEKLLKKLDIQPHLYVKEGEWVESGALLI
SAEGMSEQLHQAWKVVQLVLEWSCGVAQYTAEMIANAKSVNPTAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGVSETL
LVFTNHRNLLSDPNDWTKIVDRLRQEAPENKITLEADNYAQFEQMYMAEPDIIQLDKWLLEDVKKALDLLQSKQKDILLS
VAGGVNKNNVSDYAKLGIRLFITSAPYYVPPEDIKVVIEKI

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family

Homologues:

Organism=Saccharomyces cerevisiae, GI6321162, Length=275, Percent_Identity=24, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MODD_HAEIN (Q57278)

Other databases:

- EMBL:   L42023
- PIR:   H64125
- RefSeq:   NP_439624.1
- ProteinModelPortal:   Q57278
- SMR:   Q57278
- GeneID:   950721
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1473
- NMPDR:   fig|71421.1.peg.1404
- TIGR:   HI_1473
- HOGENOM:   HBG751540
- OMA:   VACTRKN
- ProtClustDB:   PRK06096
- BioCyc:   HINF71421:HI_1473-MONOMER
- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01334

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N; SSF51690 Q_phspho_trans

EC number: 2.4.2.-

Molecular weight: Translated: 31437; Mature: 31437

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYFSDKELDDLLLEDIYRGDLTTHALSIENIPAKILFKRKNAGVVAGVSVAEKLLKKLD
CEEECCCCHHHHHHHHHHHCCCHHEEEEECCCCEEEEEEECCCCEEEHHHHHHHHHHHCC
IQPHLYVKEGEWVESGALLISAEGMSEQLHQAWKVVQLVLEWSCGVAQYTAEMIANAKSV
CCCCEEEECCCEEECCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
NPTAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGVSETLLVFTNHRNLLSDPNDWTKIV
CCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
DRLRQEAPENKITLEADNYAQFEQMYMAEPDIIQLDKWLLEDVKKALDLLQSKQKDILLS
HHHHHHCCCCCEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEEE
VAGGVNKNNVSDYAKLGIRLFITSAPYYVPPEDIKVVIEKI
ECCCCCCCCHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MIYFSDKELDDLLLEDIYRGDLTTHALSIENIPAKILFKRKNAGVVAGVSVAEKLLKKLD
CEEECCCCHHHHHHHHHHHCCCHHEEEEECCCCEEEEEEECCCCEEEHHHHHHHHHHHCC
IQPHLYVKEGEWVESGALLISAEGMSEQLHQAWKVVQLVLEWSCGVAQYTAEMIANAKSV
CCCCEEEECCCEEECCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
NPTAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGVSETLLVFTNHRNLLSDPNDWTKIV
CCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
DRLRQEAPENKITLEADNYAQFEQMYMAEPDIIQLDKWLLEDVKKALDLLQSKQKDILLS
HHHHHHCCCCCEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEEE
VAGGVNKNNVSDYAKLGIRLFITSAPYYVPPEDIKVVIEKI
ECCCCCCCCHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800