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The map label for this gene is fecD [C]

Identifier: 16273375

GI number: 16273375

Start: 1555796

End: 1556809

Strand: Reverse

Name: fecD [C]

Synonym: HI1471

Alternate gene names: 16273375

Gene position: 1556809-1555796 (Counterclockwise)

Preceding gene: 16273376

Following gene: 16273374

Centisome position: 85.07

GC content: 44.58

Gene sequence:

>1014_bases
ATGCAGCCAGATAGTTACCCTAAAATTCTCTTTGGCTTAACGCTGTTGCTTGTGATTACCGCCGTGATTTCTTTGGGAAT
AGGGCGGTATTCTTTGTCTGTACCGCAAATTGGTCAAATTCTGTGGGCAAAAGCGACCGCACTTGAGATCGATCCAGTGC
AGCAACAGGTGATTTTTCAAGTGCGTTTACCTCGAATTTTAACCGCACTTTGCGTGGGTGCCGGTTTGGCATTGAGTGGT
GTGGTATTGCAAGGCATTTTTCGTAACCCGTTAGTGAATCCGCATATTATCGGCGTGACCTCCGGTTCAGCCTTCGGTGG
CACCTTGGCAATTTTCTTTGGATTCAGTTTATACGGCTTATTTACCAGCACTATTTTATTCGGCTTCGGCACGCTTGCCT
TGGTTTTTCTATTTAGCTTCAAATTTAATCAACGCAGCTTGTTGATGCTTATTCTTATCGGCATGATTTTAAGCGGACTT
TTTTCAGCCCTAGTGAGCCTATTGCAATACATTTCCGATACAGAAGAAAAATTGCCAAGCATTGTGTTTTGGTTGATGGG
GAGTTTTGCCACCTCTAACTGGGAAAAACTCCTCTTTTTCTTTGTCCCGTTTTTGCTGTGTAGCTCGATTTTGCTCAGCT
TAAGTTGGCGCTTGAATTTACTGTCTTTAGATGAGAAAGAAGCCAAGGCTTTGGGCGTGAAAATGGCCCCATTACGTTGG
TTAGTGATCTTTTTAAGCGGTTCGTTAGTGGCATGCCAGGTGGCAATTAGCGGCAGTATCGGCTGGGTCGGGCTGATCAT
TCCTCATCTTAGCCGTATGCTGGTAGGTGCCAATCATCAAAGTTTATTGCCTTGCACCATGCTTGTTGGGGCGACTTATA
TGTTGCTTGTGGACAATGTTGCGCGTTCCCTATCCGATGCCGAAATTCCAATCAGTATTTTGACCGCACTTATTGGTGCA
CCGTTGTTTGGTGTATTGGTATATAAACTAAAACGCGGAGGCATGAATGAATAA

Upstream 100 bases:

>100_bases
GCTAAAGCCCTTTATCCGCAACGTTTCCAAGACGTGGATTTGGATAAAATGGTGAACGATTATTACCAAAAATTCTACCG
CACTTCTTACAAACCCGACA

Downstream 100 bases:

>100_bases
AGCGCTCTCCGTGGAAAATCTAGGTTTTTATTACCAAGCGGAAAACTTCCTGTTTCAGCAACTGAATTTTGATTTGAATA
AAGGAGATATTCTGGCGGTT

Product: iron chelatin ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQPDSYPKILFGLTLLLVITAVISLGIGRYSLSVPQIGQILWAKATALEIDPVQQQVIFQVRLPRILTALCVGAGLALSG
VVLQGIFRNPLVNPHIIGVTSGSAFGGTLAIFFGFSLYGLFTSTILFGFGTLALVFLFSFKFNQRSLLMLILIGMILSGL
FSALVSLLQYISDTEEKLPSIVFWLMGSFATSNWEKLLFFFVPFLLCSSILLSLSWRLNLLSLDEKEAKALGVKMAPLRW
LVIFLSGSLVACQVAISGSIGWVGLIIPHLSRMLVGANHQSLLPCTMLVGATYMLLVDNVARSLSDAEIPISILTALIGA
PLFGVLVYKLKRGGMNE

Sequences:

>Translated_337_residues
MQPDSYPKILFGLTLLLVITAVISLGIGRYSLSVPQIGQILWAKATALEIDPVQQQVIFQVRLPRILTALCVGAGLALSG
VVLQGIFRNPLVNPHIIGVTSGSAFGGTLAIFFGFSLYGLFTSTILFGFGTLALVFLFSFKFNQRSLLMLILIGMILSGL
FSALVSLLQYISDTEEKLPSIVFWLMGSFATSNWEKLLFFFVPFLLCSSILLSLSWRLNLLSLDEKEAKALGVKMAPLRW
LVIFLSGSLVACQVAISGSIGWVGLIIPHLSRMLVGANHQSLLPCTMLVGATYMLLVDNVARSLSDAEIPISILTALIGA
PLFGVLVYKLKRGGMNE
>Mature_337_residues
MQPDSYPKILFGLTLLLVITAVISLGIGRYSLSVPQIGQILWAKATALEIDPVQQQVIFQVRLPRILTALCVGAGLALSG
VVLQGIFRNPLVNPHIIGVTSGSAFGGTLAIFFGFSLYGLFTSTILFGFGTLALVFLFSFKFNQRSLLMLILIGMILSGL
FSALVSLLQYISDTEEKLPSIVFWLMGSFATSNWEKLLFFFVPFLLCSSILLSLSWRLNLLSLDEKEAKALGVKMAPLRW
LVIFLSGSLVACQVAISGSIGWVGLIIPHLSRMLVGANHQSLLPCTMLVGATYMLLVDNVARSLSDAEIPISILTALIGA
PLFGVLVYKLKRGGMNE

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily

Homologues:

Organism=Escherichia coli, GI1790740, Length=285, Percent_Identity=31.9298245614035, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=35.2941176470588, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786805, Length=286, Percent_Identity=32.5174825174825, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1790741, Length=292, Percent_Identity=31.5068493150685, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786347, Length=321, Percent_Identity=27.7258566978193, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786804, Length=279, Percent_Identity=28.673835125448, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1471_HAEIN (Q57130)

Other databases:

- EMBL:   L42023
- PIR:   G64125
- RefSeq:   NP_439622.1
- PDB:   2NQ2
- PDBsum:   2NQ2
- ProteinModelPortal:   Q57130
- SMR:   Q57130
- GeneID:   950354
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1471
- NMPDR:   fig|71421.1.peg.1402
- TIGR:   HI_1471
- HOGENOM:   HBG700016
- OMA:   TIRMPRI
- BioCyc:   HINF71421:HI_1471-MONOMER
- InterPro:   IPR000522

Pfam domain/function: PF01032 FecCD

EC number: NA

Molecular weight: Translated: 36531; Mature: 36531

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe9597d8)-; HASH(0x8afd7a4)-; HASH(0xd164300)-; HASH(0xe8fb97c)-; HASH(0xe5536bc)-; HASH(0xdf78cac)-; HASH(0xe4be63c)-; HASH(0xe9ae134)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPDSYPKILFGLTLLLVITAVISLGIGRYSLSVPQIGQILWAKATALEIDPVQQQVIFQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEECCHHHHHHHHH
VRLPRILTALCVGAGLALSGVVLQGIFRNPLVNPHIIGVTSGSAFGGTLAIFFGFSLYGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
FTSTILFGFGTLALVFLFSFKFNQRSLLMLILIGMILSGLFSALVSLLQYISDTEEKLPS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
IVFWLMGSFATSNWEKLLFFFVPFLLCSSILLSLSWRLNLLSLDEKEAKALGVKMAPLRW
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHCCCHHHHHH
LVIFLSGSLVACQVAISGSIGWVGLIIPHLSRMLVGANHQSLLPCTMLVGATYMLLVDNV
HHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ARSLSDAEIPISILTALIGAPLFGVLVYKLKRGGMNE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MQPDSYPKILFGLTLLLVITAVISLGIGRYSLSVPQIGQILWAKATALEIDPVQQQVIFQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEECCHHHHHHHHH
VRLPRILTALCVGAGLALSGVVLQGIFRNPLVNPHIIGVTSGSAFGGTLAIFFGFSLYGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
FTSTILFGFGTLALVFLFSFKFNQRSLLMLILIGMILSGLFSALVSLLQYISDTEEKLPS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
IVFWLMGSFATSNWEKLLFFFVPFLLCSSILLSLSWRLNLLSLDEKEAKALGVKMAPLRW
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHCCCHHHHHH
LVIFLSGSLVACQVAISGSIGWVGLIIPHLSRMLVGANHQSLLPCTMLVGATYMLLVDNV
HHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ARSLSDAEIPISILTALIGAPLFGVLVYKLKRGGMNE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800