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The map label for this gene is purL [C]

Identifier: 16273359

GI number: 16273359

Start: 1537998

End: 1538468

Strand: Reverse

Name: purL [C]

Synonym: HI1453

Alternate gene names: 16273359

Gene position: 1538468-1537998 (Counterclockwise)

Preceding gene: 16273360

Following gene: 16273358

Centisome position: 84.06

GC content: 36.31

Gene sequence:

>471_bases
ATGAAAAAACTACTATCAATATTTCTAATGGCATTCAGCCTAAACGCTTTTGCACAAACTAATTTGGCGGATGTGCAACT
CAAAGATTTAAACAATCAGCCAGTTACTTTAAGCCAATATAAAGGCAAACCCGTGTATGTAAAAATGTGGGCATCTTGGT
GTCCAATTTGTTTGGCAGGATTAGCTGAAATTGATGATTTAAGTGCGGAAAAAGATCGCAATTTTGAAGTGATTACCATT
GTTTCGCCCGATCACAAAGGCGAAAAAGACACCGCTGATTTTATTGAGTGGTACAAGGGATTAGAATATAAAAATATCAC
GGTGCTTTTAGATGAAAAAGGCGAAATCATTGATAAAGCAAGAGTGCGTGGCTATCCGTTTAATCTCTTTTTAGATAGTG
ATTTAAACCTGAAAAAAACCGTACCAGGACATTTAGGTGCAGAGCAAATTCGAGTGTTTGCTGAAAAATAA

Upstream 100 bases:

>100_bases
GTGGCGGAATTTTAATTATCGTGATGGGTATTTTATTGATTACGAATAATTTTTCGTAAAACATAACCTCAACAAAAGAA
ATTTATAAAAGGAAAAAGCA

Downstream 100 bases:

>100_bases
CGATGACAAGCGGCTTATTTTTAAGCCGCTTTTTATATTCCATTTTTACAGAGTAAAGAGACAAAGTATCTAAGATTGGC
ATTTGAACATTGAGCATTTG

Product: phosphoribosylformylglycinamidine synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKKLLSIFLMAFSLNAFAQTNLADVQLKDLNNQPVTLSQYKGKPVYVKMWASWCPICLAGLAEIDDLSAEKDRNFEVITI
VSPDHKGEKDTADFIEWYKGLEYKNITVLLDEKGEIIDKARVRGYPFNLFLDSDLNLKKTVPGHLGAEQIRVFAEK

Sequences:

>Translated_156_residues
MKKLLSIFLMAFSLNAFAQTNLADVQLKDLNNQPVTLSQYKGKPVYVKMWASWCPICLAGLAEIDDLSAEKDRNFEVITI
VSPDHKGEKDTADFIEWYKGLEYKNITVLLDEKGEIIDKARVRGYPFNLFLDSDLNLKKTVPGHLGAEQIRVFAEK
>Mature_156_residues
MKKLLSIFLMAFSLNAFAQTNLADVQLKDLNNQPVTLSQYKGKPVYVKMWASWCPICLAGLAEIDDLSAEKDRNFEVITI
VSPDHKGEKDTADFIEWYKGLEYKNITVLLDEKGEIIDKARVRGYPFNLFLDSDLNLKKTVPGHLGAEQIRVFAEK

Specific function: Involved In Disulfide Bond Formation. Catalyzes A Late, Reductive Step In The Assembly Of Periplasmic C-Type Cytochromes, Probably The Reduction Of Disulfide Bonds Of The Apocytochrome C To Allow Covalent Linkage With The Heme. Possible Subunit Of A Heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1453_HAEIN (Q57127)

Other databases:

- EMBL:   L42023
- PIR:   D64124
- RefSeq:   NP_439604.1
- ProteinModelPortal:   Q57127
- SMR:   Q57127
- GeneID:   950347
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1453
- TIGR:   HI_1453
- HOGENOM:   HBG493509
- OMA:   THIGYMS
- ProtClustDB:   CLSK808527
- BioCyc:   HINF71421:HI_1453-MONOMER
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF08534 Redoxin; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 17727; Mature: 17727

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLSIFLMAFSLNAFAQTNLADVQLKDLNNQPVTLSQYKGKPVYVKMWASWCPICLAG
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCEEEEEEHHHHHHHHHHH
LAEIDDLSAEKDRNFEVITIVSPDHKGEKDTADFIEWYKGLEYKNITVLLDEKGEIIDKA
HHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHH
RVRGYPFNLFLDSDLNLKKTVPGHLGAEQIRVFAEK
HHCCCCEEEEECCCCCCEECCCCCCCHHHEEEEECC
>Mature Secondary Structure
MKKLLSIFLMAFSLNAFAQTNLADVQLKDLNNQPVTLSQYKGKPVYVKMWASWCPICLAG
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCEEEEEEHHHHHHHHHHH
LAEIDDLSAEKDRNFEVITIVSPDHKGEKDTADFIEWYKGLEYKNITVLLDEKGEIIDKA
HHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHH
RVRGYPFNLFLDSDLNLKKTVPGHLGAEQIRVFAEK
HHCCCCEEEEECCCCCCEECCCCCCCHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023