BacMap

Definition	Haemophilus influenzae Rd KW20 chromosome, complete genome.
Accession	NC_000907
Length	1,830,138

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The map label for this gene is ydfG [C]

Identifier: 16273335

GI number: 16273335

Start: 1518436

End: 1519194

Strand: Direct

Name: ydfG [C]

Synonym: HI1430

Alternate gene names: 16273335

Gene position: 1518436-1519194 (Clockwise)

Preceding gene: 16273332

Following gene: 16273336

Centisome position: 82.97

GC content: 41.5

Gene sequence:

>759_bases
ATGAAAACTACTACTGCATTAGTAACAGGTGCAACCGCAGGCTTTGGCTTGGCAATCTGTAAAAAATTGATCGAAGCAGG
CTATAAAGTGATTGGCACGGGCAGACGTGCAGATCGATTAGCAGAAATCCATTCACAATTGGGCAATAATTTTCTACCGC
TTGCCTTTGACATTCGTGATGAACAAGCCACAATTAACGCTCTAAATACCCTTCCTGAAGGCTGGCAAGCGGTCGATTTA
TTAGTGAATAATGCAGGTTTAGCCTTGGGATTAGAGCCGGCACATAAAGCGGATTTACAAGATTGGTATCAGATGATTGA
TACCAACATCAAAGGATTGGTTACTATCACTCGCCTTGTGTTGCCAAATATGGTGGCTCGTAATTACGGGCAGATTATCA
ATTTGAGTTCAATTGCAGGTACTTATCCTTATGCAGGCAGTAATGTATATGGTGGAACTAAAGCTTTTGTCACACAATTT
AGCTTAAATTTACGAGCCGATCTGGCAGGCACAAAAATTCGAGTAAGCAATGTTGAACCGGGTTTATGTGGCGGTACGGA
GTTCTCTAATGTGCGTTTTCACGGCGATGATGAAAGAGCCGCAAAAGTCTATGAAAACGTGCAATCGGTTCAGCCTGAAG
ATATTGCGAACATTGTATTATGGCTTCATCAACAACCTGAACACGTGAACATTAATCGTATTGAAGTAATGCCAACCGCT
CAATCTTTTGCAGGAATGAGCGTTTCAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
CATTTAATGACATTTTTAAAATTAAAATGAAATTGCTTGCAATCAAAATTTATTTGTACTACTTTAATAGTACAAATAAG
CTCAAGATTTAGGAGAAAAA

Downstream 100 bases:

>100_bases
AATAATAGGAAAAAATATGTCAGACACACTTCTTAACCCTTATTTTGGCGAATTTGGCGGAATGTATGTACCCGAAATTT
TAGTGCCTGTTTTAAAGCAA

Product: short chain dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKTTTALVTGATAGFGLAICKKLIEAGYKVIGTGRRADRLAEIHSQLGNNFLPLAFDIRDEQATINALNTLPEGWQAVDL
LVNNAGLALGLEPAHKADLQDWYQMIDTNIKGLVTITRLVLPNMVARNYGQIINLSSIAGTYPYAGSNVYGGTKAFVTQF
SLNLRADLAGTKIRVSNVEPGLCGGTEFSNVRFHGDDERAAKVYENVQSVQPEDIANIVLWLHQQPEHVNINRIEVMPTA
QSFAGMSVSKEK

Sequences:

>Translated_252_residues
MKTTTALVTGATAGFGLAICKKLIEAGYKVIGTGRRADRLAEIHSQLGNNFLPLAFDIRDEQATINALNTLPEGWQAVDL
LVNNAGLALGLEPAHKADLQDWYQMIDTNIKGLVTITRLVLPNMVARNYGQIINLSSIAGTYPYAGSNVYGGTKAFVTQF
SLNLRADLAGTKIRVSNVEPGLCGGTEFSNVRFHGDDERAAKVYENVQSVQPEDIANIVLWLHQQPEHVNINRIEVMPTA
QSFAGMSVSKEK
>Mature_252_residues
MKTTTALVTGATAGFGLAICKKLIEAGYKVIGTGRRADRLAEIHSQLGNNFLPLAFDIRDEQATINALNTLPEGWQAVDL
LVNNAGLALGLEPAHKADLQDWYQMIDTNIKGLVTITRLVLPNMVARNYGQIINLSSIAGTYPYAGSNVYGGTKAFVTQF
SLNLRADLAGTKIRVSNVEPGLCGGTEFSNVRFHGDDERAAKVYENVQSVQPEDIANIVLWLHQQPEHVNINRIEVMPTA
QSFAGMSVSKEK

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI109715829, Length=247, Percent_Identity=31.1740890688259, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI7705855, Length=193, Percent_Identity=30.5699481865285, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI157739938, Length=188, Percent_Identity=25.531914893617, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI32483357, Length=229, Percent_Identity=27.5109170305677, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI19923817, Length=192, Percent_Identity=27.6041666666667, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=228, Percent_Identity=30.2631578947368, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI150247226, Length=195, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7706318, Length=182, Percent_Identity=29.6703296703297, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI40254992, Length=176, Percent_Identity=28.4090909090909, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=28.5, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7657478, Length=184, Percent_Identity=29.3478260869565, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4557649, Length=180, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4504503, Length=180, Percent_Identity=30.5555555555556, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40548397, Length=178, Percent_Identity=26.9662921348315, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI214010158, Length=178, Percent_Identity=26.9662921348315, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI214010156, Length=178, Percent_Identity=26.9662921348315, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI22758144, Length=178, Percent_Identity=26.9662921348315, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI31542939, Length=188, Percent_Identity=28.7234042553192, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7705925, Length=176, Percent_Identity=30.1136363636364, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22507405, Length=177, Percent_Identity=27.683615819209, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=245, Percent_Identity=58.3673469387755, Blast_Score=308, Evalue=2e-85,
Organism=Escherichia coli, GI1787335, Length=220, Percent_Identity=31.8181818181818, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=181, Percent_Identity=33.1491712707182, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786812, Length=240, Percent_Identity=25, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI2367175, Length=231, Percent_Identity=26.4069264069264, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1789208, Length=236, Percent_Identity=24.5762711864407, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=239, Percent_Identity=29.2887029288703, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=200, Percent_Identity=29.5, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=201, Percent_Identity=27.363184079602, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=246, Percent_Identity=27.6422764227642, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=235, Percent_Identity=30.2127659574468, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=242, Percent_Identity=26.8595041322314, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=237, Percent_Identity=30.379746835443, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=237, Percent_Identity=29.1139240506329, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=237, Percent_Identity=27.4261603375527, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=222, Percent_Identity=26.5765765765766, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=243, Percent_Identity=27.1604938271605, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=240, Percent_Identity=27.5, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=248, Percent_Identity=27.0161290322581, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=237, Percent_Identity=27.8481012658228, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=237, Percent_Identity=26.1603375527426, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=244, Percent_Identity=25.8196721311475, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=227, Percent_Identity=28.1938325991189, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=238, Percent_Identity=27.3109243697479, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=231, Percent_Identity=25.974025974026, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=182, Percent_Identity=32.4175824175824, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=242, Percent_Identity=25.2066115702479, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=35.2226720647773, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6322227, Length=197, Percent_Identity=26.9035532994924, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=181, Percent_Identity=30.3867403314917, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=188, Percent_Identity=25, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364494, Length=252, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI116007236, Length=252, Percent_Identity=28.968253968254, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641232, Length=254, Percent_Identity=29.9212598425197, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24641388, Length=251, Percent_Identity=29.0836653386454, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24643142, Length=174, Percent_Identity=35.0574712643678, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI116007234, Length=253, Percent_Identity=29.2490118577075, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648693, Length=253, Percent_Identity=27.6679841897233, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21355889, Length=253, Percent_Identity=27.6679841897233, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI23397609, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571387, Length=253, Percent_Identity=28.0632411067194, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=31.4720812182741, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24663911, Length=251, Percent_Identity=27.4900398406374, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21358495, Length=237, Percent_Identity=29.1139240506329, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=186, Percent_Identity=31.1827956989247, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571526, Length=214, Percent_Identity=28.0373831775701, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI116007238, Length=183, Percent_Identity=31.6939890710383, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24648944, Length=242, Percent_Identity=25.6198347107438, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161076933, Length=197, Percent_Identity=25.3807106598985, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24584748, Length=197, Percent_Identity=25.3807106598985, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17737361, Length=195, Percent_Identity=28.7179487179487, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644339, Length=222, Percent_Identity=26.1261261261261, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=30.1204819277108, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584744, Length=185, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007232, Length=188, Percent_Identity=32.4468085106383, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574402, Length=185, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): Y1430_HAEIN (P45200)

Other databases:

- EMBL:   L42023
- PIR:   H64122
- RefSeq:   NP_439579.1
- ProteinModelPortal:   P45200
- SMR:   P45200
- GeneID:   950332
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1430
- NMPDR:   fig|71421.1.peg.1362
- TIGR:   HI_1430
- HOGENOM:   HBG750976
- OMA:   SVIGCAR
- ProtClustDB:   CLSK892407
- BioCyc:   HINF71421:HI_1430-MONOMER
- GO:   GO:0005488
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081
- PRINTS:   PR00080

Pfam domain/function: PF00106 adh_short

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27399; Mature: 27399

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 150-150 BINDING 137-137

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTTALVTGATAGFGLAICKKLIEAGYKVIGTGRRADRLAEIHSQLGNNFLPLAFDIRD
CCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEEECC
EQATINALNTLPEGWQAVDLLVNNAGLALGLEPAHKADLQDWYQMIDTNIKGLVTITRLV
CHHHHHHHHCCCCCHHEEHHEECCCCEEEECCCHHHCCHHHHHHHHHCCCHHHHHHHHHH
LPNMVARNYGQIINLSSIAGTYPYAGSNVYGGTKAFVTQFSLNLRADLAGTKIRVSNVEP
HHHHHHHCCCCEEEEHHHCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCEEEECCCCC
GLCGGTEFSNVRFHGDDERAAKVYENVQSVQPEDIANIVLWLHQQPEHVNINRIEVMPTA
CCCCCCCCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCEEEEEEECH
QSFAGMSVSKEK
HHHCCCCCCCCC
>Mature Secondary Structure
MKTTTALVTGATAGFGLAICKKLIEAGYKVIGTGRRADRLAEIHSQLGNNFLPLAFDIRD
CCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEEECC
EQATINALNTLPEGWQAVDLLVNNAGLALGLEPAHKADLQDWYQMIDTNIKGLVTITRLV
CHHHHHHHHCCCCCHHEEHHEECCCCEEEECCCHHHCCHHHHHHHHHCCCHHHHHHHHHH
LPNMVARNYGQIINLSSIAGTYPYAGSNVYGGTKAFVTQFSLNLRADLAGTKIRVSNVEP
HHHHHHHCCCCEEEEHHHCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCEEEECCCCC
GLCGGTEFSNVRFHGDDERAAKVYENVQSVQPEDIANIVLWLHQQPEHVNINRIEVMPTA
CCCCCCCCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCEEEEEEECH
QSFAGMSVSKEK
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800