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The map label for this gene is fnr

Identifier: 16273330

GI number: 16273330

Start: 1513585

End: 1514358

Strand: Direct

Name: fnr

Synonym: HI1425

Alternate gene names: 16273330

Gene position: 1513585-1514358 (Clockwise)

Preceding gene: 16273328

Following gene: 161350020

Centisome position: 82.7

GC content: 34.63

Gene sequence:

>774_bases
ATGAAAAATTTCGTTGCAGGAGCTCAATCAGGGCGCAAAATTCAATCAGGCGGTTGTGCGATTCATTGTCAGGATTGCAG
TATTAGTCAGCTTTGTATTCCTTTTACCTTAAATGAACAAGAATTAGATCAGCTTGATAATATCATAGAGAGAAAAAAAC
CGATTCAAAAGTCTCAAGTATTATTTAAAGCAGGAGATTCTCTCAATTCAATTTATGCTATTCGTTCTGGCACAATAAAA
AGCTATACGATTAGTGAATCTGGCGAAGAACAAATTACTTCATTTCATTTGCCCGGTGACCTAGTTGGTTTTGATGCCAT
TACTCAAATGCAACACCCTAGTTTTGCACAAGCTCTAGAAACGGCTATGGTATGTGAAATTCCTTTTGATATTTTAGATG
ATTTGGCAGGAAAAATGCCAAAACTACGCCAGCAAATTTTACGTTTGATGAGCAGTGAAATTAAAAGTGATCAAGAGATG
ATTTTATTGCTATCTAAAATGAATGCAGAAGAACGTTTGGCTGCTTTTATTCATAATCTTTCTAAACGCTATTCTGCTCG
AGGTTTTTCAGCAAGAGAATTTCGTTTAACAATGACACGTGGCGATATTGGTAATTATCTAGGTTTAACAGTAGAAACCA
TCAGCCGCTTATTAGGCCGCTTTCAAAAACTCGGCGTGATTAGCGTACAAGGCAAATATATTACAATCAATGATTTAAAT
GGTTTAATTGAATTAACTGGTACGAATAAAACAAAAATTACATTAGTTAAATAA

Upstream 100 bases:

>100_bases
CCATAATGCTTTACTCTTCTTAATCTGACTAAACTAATTAGTGGTAGAATATTTGCGTTAGATCAATTTTACACTATTTT
TTTCAATATTTGAGGCGTAC

Downstream 100 bases:

>100_bases
ATTTAAGCGTGAATATCACGCCTTTTTGTGCTTGATAAAAATAAATTTATCCAAATTAATCTTGTACCTTGCCATTTTTG
CTATTCTTTTTTATCCTATG

Product: fumarate/nitrate reduction transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKAGDSLNSIYAIRSGTIK
SYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALETAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEM
ILLLSKMNAEERLAAFIHNLSKRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
GLIELTGTNKTKITLVK

Sequences:

>Translated_257_residues
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKAGDSLNSIYAIRSGTIK
SYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALETAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEM
ILLLSKMNAEERLAAFIHNLSKRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
GLIELTGTNKTKITLVK
>Mature_257_residues
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKAGDSLNSIYAIRSGTIK
SYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALETAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEM
ILLLSKMNAEERLAAFIHNLSKRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
GLIELTGTNKTKITLVK

Specific function: It is involved in the activation of genes necessary for anaerobic respiration

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787595, Length=240, Percent_Identity=79.1666666666667, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FNR_HAEIN (P45199)

Other databases:

- EMBL:   L42023
- PIR:   E64122
- RefSeq:   NP_439574.1
- ProteinModelPortal:   P45199
- GeneID:   950327
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1425
- TIGR:   HI_1425
- HOGENOM:   HBG753167
- OMA:   FSANQFR
- ProtClustDB:   PRK11161
- BioCyc:   HINF71421:HI_1425-MONOMER
- GO:   GO:0005737
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991
- Gene3D:   G3DSA:2.60.120.10
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00034
- SMART:   SM00100
- SMART:   SM00419

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp; SSF51206 cNMP_binding

EC number: NA

Molecular weight: Translated: 28596; Mature: 28596

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50042 CNMP_BINDING_3; PS00042 HTH_CRP_1; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQV
CCCCCCCCCCCCEECCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCHHHH
LFKAGDSLNSIYAIRSGTIKSYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALE
HHHCCCCCCEEEEEECCCEEEEEECCCCCHHHEEECCCCCHHHHHHHHHCCCCHHHHHHH
TAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEMILLLSKMNAEERLAAFIHNL
HHHHEECCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
SKRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
HHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCC
GLIELTGTNKTKITLVK
CEEEEECCCCEEEEEEC
>Mature Secondary Structure
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQV
CCCCCCCCCCCCEECCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCHHHH
LFKAGDSLNSIYAIRSGTIKSYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALE
HHHCCCCCCEEEEEECCCEEEEEECCCCCHHHEEECCCCCHHHHHHHHHCCCCHHHHHHH
TAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEMILLLSKMNAEERLAAFIHNL
HHHHEECCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
SKRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
HHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCC
GLIELTGTNKTKITLVK
CEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800