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The map label for this gene is uup-A [H]

Identifier: 16273253

GI number: 16273253

Start: 1418744

End: 1420123

Strand: Direct

Name: uup-A [H]

Synonym: HI1342

Alternate gene names: 16273253

Gene position: 1418744-1420123 (Clockwise)

Preceding gene: 16273249

Following gene: 16273258

Centisome position: 77.52

GC content: 39.93

Gene sequence:

>1380_bases
GTGGAAGCTATTGAATGGTTGGAAAATTTCTTACTGGATTTCCAAGGTAGCATTGTATTTATTTCCCATGACCGTTCTGT
TATTCGCAAAATGGCAACACGCATTGTGGATTTAGATCGCGGTCAATTGCAGTCTTATCTAGGCAATTACGATTTATATT
TAACCACGAAAGAAGAAAATCTACGCGTTGAAGCCTTGCAGAATGAATTATTTGATAAACGTCTTGCACAGGAAGATGTA
TGGATTCGCCAAGGTATCAAGGCTCGCCGTACAAGAAATGAAGGGCGAGTGCGAGCATTAAAAGCGATGCGTGAGGAACG
CCGCCAACGCCGTGAGGTAATGGGAACAGCCAAATTACAGTTAGATACCTCAAGTCGTTCTGGCAAAATTGTCTTTGAAA
TGGAAGATGTGAGCTATGAAATCGCAGGAAAAACCTTGTTAAAAGATTTTTCAACAACGATTTTACGTGGAGACAAAATT
GCGCTTGTTGGGCCAAATGGCTGTGGGAAAACCACGTTCATTAAATTATTGCTGGGGGAAATTCAGCCAACATCAGGCAA
AATCCGTTGTGGTACTAAATTAGAGATTGCTTATTTTGACCAATACCGTGCTGATTTAGATCCTGAAAAAATTGTAATGG
ATAATGTGGCAGATGGTAAACAAGATATTGAAATCAATGGTGTAAAACGCCATGTACTAGGGTATTTGCAAGAGTTCTTG
TTCCCACCAAAACGAGCAATGACCCCAGTTAAAGCCTTATCGGGGGGAGAACGAAATCGTTTATTGCTCGCAAAATTGTT
GCTCAAACCAAATAATTTATTGATTCTTGACGAACCAACCAATGACCTTGATGTAGAAACATTGGAGCTTTTAGAGGAAA
TTTTGACTGATTATCAAGGCACATTGTTAATTGTGAGCCATGACCGTCAATTTATCGATAATACTGCGACAGAATGTTAT
TTATTCGAAGGTGAAGGGCGTTTGAATAAGTATGTGGGTGGATTCTTTGATGCGAAACAGCAACAAGCCAATTTCTGGGC
AAGCAAAGCGGTGGAAGAACAGGCTAAGGCGAAGAAATCTGAACCACTAAAAGAAGAAAGTGCGGTGAAAAATGACCGCA
CTTCTAAGCCGAAATCCGTGAAACTTTCTTATAAAGAACAACGAGAGCTAGAGCAACTTCCACAACTTTTGGAAGAATTA
GAAACTAAAATCACCACACTTCAAGCTGAAATAGCCGATCCAGCATTTTTCCAACAAGCTCACGATATTACCGACGCTAA
ATTAAAAGCATTGGCGGATACTGAAGCCGAATTAGAAACAGCATTTTTACGCTGGGAAGAATTAGAAGAAAAGAAAAATT
TGGCTGACGGTAAAGCTTAA

Upstream 100 bases:

>100_bases
ATTATCTAAAATCGGTAAAACTCGAATTTTTGCACCGCACTTTTTCGCCGTTTCATGCCAAGTGACAAAATTAGCAACTT
GATGAACCAACCACTTGGAT

Downstream 100 bases:

>100_bases
AAAATAACGCCCGAAAGGGCGTTTTTATTTAGAGGAAATATTGCACAGAATCATATTTTAATTCTTTGCTAATTGACCAA
TTATTTTGCTGCTTTTAATT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MEAIEWLENFLLDFQGSIVFISHDRSVIRKMATRIVDLDRGQLQSYLGNYDLYLTTKEENLRVEALQNELFDKRLAQEDV
WIRQGIKARRTRNEGRVRALKAMREERRQRREVMGTAKLQLDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKI
ALVGPNGCGKTTFIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKIVMDNVADGKQDIEINGVKRHVLGYLQEFL
FPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEEILTDYQGTLLIVSHDRQFIDNTATECY
LFEGEGRLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEEL
ETKITTLQAEIADPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKKNLADGKA

Sequences:

>Translated_459_residues
MEAIEWLENFLLDFQGSIVFISHDRSVIRKMATRIVDLDRGQLQSYLGNYDLYLTTKEENLRVEALQNELFDKRLAQEDV
WIRQGIKARRTRNEGRVRALKAMREERRQRREVMGTAKLQLDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKI
ALVGPNGCGKTTFIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKIVMDNVADGKQDIEINGVKRHVLGYLQEFL
FPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEEILTDYQGTLLIVSHDRQFIDNTATECY
LFEGEGRLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEEL
ETKITTLQAEIADPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKKNLADGKA
>Mature_459_residues
MEAIEWLENFLLDFQGSIVFISHDRSVIRKMATRIVDLDRGQLQSYLGNYDLYLTTKEENLRVEALQNELFDKRLAQEDV
WIRQGIKARRTRNEGRVRALKAMREERRQRREVMGTAKLQLDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKI
ALVGPNGCGKTTFIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKIVMDNVADGKQDIEINGVKRHVLGYLQEFL
FPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEEILTDYQGTLLIVSHDRQFIDNTATECY
LFEGEGRLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEEL
ETKITTLQAEIADPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKKNLADGKA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=344, Percent_Identity=30.2325581395349, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI10947137, Length=375, Percent_Identity=28, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI27881506, Length=375, Percent_Identity=28, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI69354671, Length=353, Percent_Identity=27.7620396600567, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI10947135, Length=353, Percent_Identity=27.7620396600567, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI171184400, Length=220, Percent_Identity=29.0909090909091, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787182, Length=453, Percent_Identity=66.887417218543, Blast_Score=583, Evalue=1e-168,
Organism=Escherichia coli, GI2367384, Length=351, Percent_Identity=35.3276353276353, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1787041, Length=324, Percent_Identity=31.7901234567901, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789751, Length=471, Percent_Identity=26.5392781316348, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI1788165, Length=193, Percent_Identity=30.5699481865285, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081791, Length=205, Percent_Identity=32.6829268292683, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786563, Length=249, Percent_Identity=28.1124497991968, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787164, Length=225, Percent_Identity=32, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081834, Length=190, Percent_Identity=30.5263157894737, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788761, Length=198, Percent_Identity=28.2828282828283, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787712, Length=195, Percent_Identity=29.2307692307692, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=360, Percent_Identity=26.9444444444444, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17555318, Length=358, Percent_Identity=29.0502793296089, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17553372, Length=352, Percent_Identity=31.25, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321121, Length=348, Percent_Identity=29.0229885057471, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320874, Length=336, Percent_Identity=27.6785714285714, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324314, Length=206, Percent_Identity=32.5242718446602, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323278, Length=251, Percent_Identity=29.0836653386454, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6325030, Length=219, Percent_Identity=30.1369863013699, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642252, Length=375, Percent_Identity=30.6666666666667, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI18859989, Length=375, Percent_Identity=30.6666666666667, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24641342, Length=353, Percent_Identity=28.8951841359773, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24666836, Length=346, Percent_Identity=28.6127167630058, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281363262, Length=219, Percent_Identity=26.4840182648402, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24653245, Length=219, Percent_Identity=26.4840182648402, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 52468; Mature: 52468

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIEWLENFLLDFQGSIVFISHDRSVIRKMATRIVDLDRGQLQSYLGNYDLYLTTKEEN
CCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCC
LRVEALQNELFDKRLAQEDVWIRQGIKARRTRNEGRVRALKAMREERRQRREVMGTAKLQ
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE
LDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGE
EECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
IQPTSGKIRCGTKLEIAYFDQYRADLDPEKIVMDNVADGKQDIEINGVKRHVLGYLQEFL
CCCCCCCEEECCEEEEEEEHHHHCCCCHHHEECCCCCCCCCCEEECHHHHHHHHHHHHHC
FPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEEILTDYQG
CCCHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCC
TLLIVSHDRQFIDNTATECYLFEGEGRLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKS
EEEEEECCHHHHCCCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEELETKITTLQAEIADPAFFQQA
CCCCHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HDITDAKLKALADTEAELETAFLRWEELEEKKNLADGKA
HCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEAIEWLENFLLDFQGSIVFISHDRSVIRKMATRIVDLDRGQLQSYLGNYDLYLTTKEEN
CCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCC
LRVEALQNELFDKRLAQEDVWIRQGIKARRTRNEGRVRALKAMREERRQRREVMGTAKLQ
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE
LDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGE
EECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
IQPTSGKIRCGTKLEIAYFDQYRADLDPEKIVMDNVADGKQDIEINGVKRHVLGYLQEFL
CCCCCCCEEECCEEEEEEEHHHHCCCCHHHEECCCCCCCCCCEEECHHHHHHHHHHHHHC
FPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEEILTDYQG
CCCHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCC
TLLIVSHDRQFIDNTATECYLFEGEGRLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKS
EEEEEECCHHHHCCCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEELETKITTLQAEIADPAFFQQA
CCCCHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HDITDAKLKALADTEAELETAFLRWEELEEKKNLADGKA
HCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]