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The map label for this gene is ihfA

Identifier: 16273225

GI number: 16273225

Start: 1391712

End: 1392002

Strand: Direct

Name: ihfA

Synonym: HI1313

Alternate gene names: 16273225

Gene position: 1391712-1392002 (Clockwise)

Preceding gene: 16273224

Following gene: 16273226

Centisome position: 76.04

GC content: 37.8

Gene sequence:

>291_bases
ATGGCTACGATAACTAAACTTGATATTATTGAATATTTAAGCGATAAATATCACTTATCTAAACAAGATACGAAAAATGT
AGTGGAGAACTTTTTGGAAGAGATCCGCTTATCGCTAGAATCTGGTCAAGATGTGAAATTATCAGGATTTGGTAATTTTG
AATTACGCGATAAGTCATCTCGCCCAGGGCGTAACCCAAAAACAGGTGATGTTGTGCCAGTTTCTGCTCGCCGAGTAGTG
ACATTTAAACCTGGGCAAAAGTTACGTGCCCGTGTAGAAAAAACTAAATAG

Upstream 100 bases:

>100_bases
GATAATGAAAAAACACTTGAAGATGAAGAAATTAATGCAGTGATTTCAGCAGTATTAGCGGAGGTAAAACAACGCTTTAA
TGCTGAATTAAGGGATTAAT

Downstream 100 bases:

>100_bases
TAAGCAACAAAAAGTGCGGTGAATTTCTACCGCACTTTTCATATGAAAAGGTATGAAAGTATATAAATCATTTTTAATCG
CTACTGCATCGCTGTTTTTA

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MATITKLDIIEYLSDKYHLSKQDTKNVVENFLEEIRLSLESGQDVKLSGFGNFELRDKSSRPGRNPKTGDVVPVSARRVV
TFKPGQKLRARVEKTK

Sequences:

>Translated_96_residues
MATITKLDIIEYLSDKYHLSKQDTKNVVENFLEEIRLSLESGQDVKLSGFGNFELRDKSSRPGRNPKTGDVVPVSARRVV
TFKPGQKLRARVEKTK
>Mature_95_residues
ATITKLDIIEYLSDKYHLSKQDTKNVVENFLEEIRLSLESGQDVKLSGFGNFELRDKSSRPGRNPKTGDVVPVSARRVVT
FKPGQKLRARVEKTK

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=91, Percent_Identity=65.9340659340659, Blast_Score=129, Evalue=4e-32,
Organism=Escherichia coli, GI1787141, Length=90, Percent_Identity=37.7777777777778, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1790433, Length=86, Percent_Identity=36.046511627907, Blast_Score=65, Evalue=9e-13,
Organism=Escherichia coli, GI1786644, Length=86, Percent_Identity=30.2325581395349, Blast_Score=62, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_HAEI8 (Q4QKM2)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_249085.1
- HSSP:   P0A6X7
- ProteinModelPortal:   Q4QKM2
- SMR:   Q4QKM2
- STRING:   Q4QKM2
- GeneID:   3430862
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI1626
- eggNOG:   COG0776
- HOGENOM:   HBG705085
- OMA:   VRGETVK
- PhylomeDB:   Q4QKM2
- ProtClustDB:   PRK00285
- BioCyc:   HINF281310:NTHI1626-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 10907; Mature: 10775

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATITKLDIIEYLSDKYHLSKQDTKNVVENFLEEIRLSLESGQDVKLSGFGNFELRDKSS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCC
RPGRNPKTGDVVPVSARRVVTFKPGQKLRARVEKTK
CCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHCCC
>Mature Secondary Structure 
ATITKLDIIEYLSDKYHLSKQDTKNVVENFLEEIRLSLESGQDVKLSGFGNFELRDKSS
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCC
RPGRNPKTGDVVPVSARRVVTFKPGQKLRARVEKTK
CCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA