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The map label for this gene is sucC [H]

Identifier: 16273116

GI number: 16273116

Start: 1262121

End: 1263290

Strand: Direct

Name: sucC [H]

Synonym: HI1196

Alternate gene names: 16273116

Gene position: 1262121-1263290 (Clockwise)

Preceding gene: 16273647

Following gene: 16273117

Centisome position: 68.96

GC content: 41.71

Gene sequence:

>1170_bases
ATGAATTTACACGAATACCAAGCAAAACAACTATTTGAGCATTATGGATTACCCGTAAAAAATGGGGCAGTCTGTCAATC
TGTTGAGGATGTCGATTTGGTACTGGCTCAACTTTCAGGCGGTAAGTGGGCAGCGAAATGCCAAGTTCATGCTGGTGGGC
GTGGTAAAGCGGGTGGCGTTAAATTGGTACAGGATGTAGAGGAAGCGAGAGCTTTTGCAGAAAAATGGCTGGGACAACGT
TTAGTCACTTTTCAAACGGATAAATTGGGTCAGCCAGTAAACCAGATTTATTTTGAAGAAACTTGCGATATTGATAAAGA
ATTTTACTTAAGTGCGGTTGTTGATCGCACCTCTCAAAAAGTGGTGTTTATTGCTTCCTCTGAGGGTGGAATGAATATTG
AAGAAGTCGTGCAAAATTCACCGCACTTACTCCATAAAGTAACCATTGATCCTTTATTTGGAGGATTGCCTTATCAAGGC
CGTGAATTGGCGTTTAAATTAGGGTTAAGTGGTACGCAAAACAAACAGTTTACCGATATCTTTATGGGCTTATCTCGTTT
GTTTTTAGAAAAAGATTTATCTTTACTGGAAGTCAATCCGCTTGTTCTCACTCCACAAGGCAATTTGGTTTGTCTCGATG
CCAAAATATCTGTCGATGATAACGCTTTATTTCGCCATAAAGATTTATTAGCACTGCAAGATTTAACTCAAAATGATGCC
CGTGAAGCAGAAGCTGAAAAATTCCAGTTAAACTATGTGGCTTTAGAGGGCGATATTGGTTGTATGGTAAACGGGGCTGG
GCTTGCAATGGGCACCATGGATATTGTGAAACTCTATGGTGGGAAGCCTGCGAATTTTCTTGATGTGGGTGGTGGTGCAA
CGCAAGAGCGGGTTGCTGAAGCGTTCAAAATCATTTTAACCGATCCTTCCGTTAAAGTGATTTTAGTGAATATTTTTGGT
GGCATTGTTCGTTGTGATTTGATTGCTGAAGGTGTGATTGCTGCAGTAAATGAAGTGGGCGTGAGAGTGCCTGTGGTTGT
GCGATTAGAAGGAACGAATGCTGAAATGGGTCGCCAAATTTTAGCGGAAAGCGACGTTAATATTCTTACCGCACAGAGTT
TACAACAAGCCGCAGAATTAGCCGTGAATGCAGCAAAAGGAGAACACTAA

Upstream 100 bases:

>100_bases
TCCAAGCAAAACATTTATATCACGATCGTGAAGAAATCACGGTTCATATAGCATTAAAACCTTGAGTGAACTGTTTTCAT
AACCAAAAAGGACGTCGCGA

Downstream 100 bases:

>100_bases
TGGCGATTTTAATTGATAAAAATACCAAAGTGATTTGCCAAGGTTTTACTGGTGGACAAGGGACTTTTCATTCTGAACAA
GCATTGGCCTACGGAACGCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNLHEYQAKQLFEHYGLPVKNGAVCQSVEDVDLVLAQLSGGKWAAKCQVHAGGRGKAGGVKLVQDVEEARAFAEKWLGQR
LVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRTSQKVVFIASSEGGMNIEEVVQNSPHLLHKVTIDPLFGGLPYQG
RELAFKLGLSGTQNKQFTDIFMGLSRLFLEKDLSLLEVNPLVLTPQGNLVCLDAKISVDDNALFRHKDLLALQDLTQNDA
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATQERVAEAFKIILTDPSVKVILVNIFG
GIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEMGRQILAESDVNILTAQSLQQAAELAVNAAKGEH

Sequences:

>Translated_389_residues
MNLHEYQAKQLFEHYGLPVKNGAVCQSVEDVDLVLAQLSGGKWAAKCQVHAGGRGKAGGVKLVQDVEEARAFAEKWLGQR
LVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRTSQKVVFIASSEGGMNIEEVVQNSPHLLHKVTIDPLFGGLPYQG
RELAFKLGLSGTQNKQFTDIFMGLSRLFLEKDLSLLEVNPLVLTPQGNLVCLDAKISVDDNALFRHKDLLALQDLTQNDA
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATQERVAEAFKIILTDPSVKVILVNIFG
GIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEMGRQILAESDVNILTAQSLQQAAELAVNAAKGEH
>Mature_389_residues
MNLHEYQAKQLFEHYGLPVKNGAVCQSVEDVDLVLAQLSGGKWAAKCQVHAGGRGKAGGVKLVQDVEEARAFAEKWLGQR
LVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRTSQKVVFIASSEGGMNIEEVVQNSPHLLHKVTIDPLFGGLPYQG
RELAFKLGLSGTQNKQFTDIFMGLSRLFLEKDLSLLEVNPLVLTPQGNLVCLDAKISVDDNALFRHKDLLALQDLTQNDA
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATQERVAEAFKIILTDPSVKVILVNIFG
GIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEMGRQILAESDVNILTAQSLQQAAELAVNAAKGEH

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=43.0769230769231, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI157779135, Length=382, Percent_Identity=43.1937172774869, Blast_Score=304, Evalue=7e-83,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=43.9226519337017, Blast_Score=295, Evalue=6e-80,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=64.9484536082474, Blast_Score=511, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=40.5, Blast_Score=314, Evalue=6e-86,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=42.0103092783505, Blast_Score=301, Evalue=5e-82,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=41.0714285714286, Blast_Score=312, Evalue=5e-86,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=44.0203562340967, Blast_Score=318, Evalue=5e-87,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=44.0203562340967, Blast_Score=318, Evalue=5e-87,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=44.1624365482233, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=44.1624365482233, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=42.9292929292929, Blast_Score=298, Evalue=4e-81,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42165; Mature: 42165

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFEHYGLPVKNGAVCQSVEDVDLVLAQLSGGKWAAKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCH
KLVQDVEEARAFAEKWLGQRLVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRTSQK
HHHHHHHHHHHHHHHHHCCEEEEEECHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCE
VVFIASSEGGMNIEEVVQNSPHLLHKVTIDPLFGGLPYQGRELAFKLGLSGTQNKQFTDI
EEEEEECCCCCCHHHHHCCCCCEEEEEEECHHHCCCCCCCCEEEEEECCCCCCCCHHHHH
FMGLSRLFLEKDLSLLEVNPLVLTPQGNLVCLDAKISVDDNALFRHKDLLALQDLTQNDA
HHHHHHHHHHCCCCEEEECCEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHH
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATQERVAE
HHHHHHEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILTDPSVKVILVNIFGGIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEMGRQI
HHEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHH
LAESDVNILTAQSLQQAAELAVNAAKGEH
HHCCCCCEEEHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLHEYQAKQLFEHYGLPVKNGAVCQSVEDVDLVLAQLSGGKWAAKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCH
KLVQDVEEARAFAEKWLGQRLVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRTSQK
HHHHHHHHHHHHHHHHHCCEEEEEECHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCE
VVFIASSEGGMNIEEVVQNSPHLLHKVTIDPLFGGLPYQGRELAFKLGLSGTQNKQFTDI
EEEEEECCCCCCHHHHHCCCCCEEEEEEECHHHCCCCCCCCEEEEEECCCCCCCCHHHHH
FMGLSRLFLEKDLSLLEVNPLVLTPQGNLVCLDAKISVDDNALFRHKDLLALQDLTQNDA
HHHHHHHHHHCCCCEEEECCEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHH
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATQERVAE
HHHHHHEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILTDPSVKVILVNIFGGIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEMGRQI
HHEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHH
LAESDVNILTAQSLQQAAELAVNAAKGEH
HHCCCCCEEEHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA