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The map label for this gene is ydjN [C]

Identifier: 16273079

GI number: 16273079

Start: 1221872

End: 1223194

Strand: Direct

Name: ydjN [C]

Synonym: HI1154

Alternate gene names: 16273079

Gene position: 1221872-1223194 (Clockwise)

Preceding gene: 16273078

Following gene: 30995427

Centisome position: 66.76

GC content: 43.84

Gene sequence:

>1323_bases
ATGTTATTAGTCAATTTGGCGATATTTATTGCTTTTTTATTGCTGTTAGCACAGCTATATCGCAAAACCGAAAAATTAGG
GCAAACGGTATTTATCGGTTTATTGCTCGGTTTGCTTTTTGGTGCGGTATTGCAATCTGCTTTTGAAAAACCTTTGTTAG
ACAAAACTTTAGATTGGATCAACGTGGTCAGTAACGGTTATGTTCGTTTATTGCAGATGATCGTGATGCCGTTGGTGTTC
GTGTCGATTTTATCTGCTATCGCTCGTATCAATCAAACCAGATCATTGGGCAAAGTCAGCGTTGGCGTGTTATCCACCTT
GCTGATTACCACCGCCATTTCCGCTGCAATTGGGATTGCGATGGTGCATTTATTTGATGTGTCGGCGGCAGGATTAATCG
TGGGCGATCGTGAATTAGCGGCTCAAGGCAAAGTGTTAGATAAAGCAGGGCAAGTGTCCAATTTAACTGTGCCTGCGATG
TTGGTGTCCTTTATTCCGAAAAATCCTTTTGCTGATCTCACGGGTGCCAACCCAACGTCCATTATTAGTGTCGTAATTTT
CTCAGCATTACTTGGCGTGGCGGCTTTGAGTTTAGGCAAAGAAGATCAAGCACTTGGCGAACGAATTGCACAAGGTGTAG
AAACTTTAAACAAATTAGTGATGCGTTTGGTGCGTTTTGTGATTCGCTTAACCCCTTACGGCGTGTTTGCGTTGATGATT
AAAATGGCTGCCACCTCAAAATGGGCGGATATTGTCAATTTGGGCAATTTTATTGTGGCTTCTTACGCTGCTATTGCCTT
AATGTTTGTGGTTCACGGCATTTTATTGTTCTTCGTTAAAGTCAATCCTGTGGATTACTACAAAAAAGTGTTGCCAACCT
TAAGTTTTGCGTTTACATCTCGCTCAAGTGCGGCAACAATTCCGTTAAATATTGAAACGCAAACCGCAAAATTAGGTAAC
AACAATGTCATCGCCAACTTTGCTGCCACATTCGGTGCCACTATCGGACAAAACGGCTGTGGCGGCATTTATCCAGCGAT
GCTTGCTGTAATGGTCGCCCCAATGGTCGGCATTGACCCTTTTAGTTTCAGCTACATTCTAACCTTAATTTTCGTGGTCG
CCATTTCTTCATTCGGCATCGCAGGCGTAGGTGGCGGAGCCACATTCGCCGCTATCGTCGTGCTATCTACGTTAGGTTTA
CCACTGGAATTAATCGGTTTACTCATTTCCATCGAACCGATCATCGATATGGGACGTACCGCACTTAACGTAAACGGTGC
CATGGTGGCAGGCACGATTACGGATCGCTTGCTAAATAAGTAA

Upstream 100 bases:

>100_bases
TTTTAATTACCAAAAAGCATAAAATATAACGAAAGAAAACTTGTTATTTTTGCTGAAGTTGATAGTCTCCAAACACTTTA
ATCAGTTTTGGAGATTTTTT

Downstream 100 bases:

>100_bases
CTGGAAATCAATAAAAAAATCTGCAATTGAGAATTCAGTTGCAGATTTTTTATCGCTCAATACTTTTGACTAAAAAGTGC
GGTGGTTTTTTTCAGTGTTT

Product: proton glutamate symport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MLLVNLAIFIAFLLLLAQLYRKTEKLGQTVFIGLLLGLLFGAVLQSAFEKPLLDKTLDWINVVSNGYVRLLQMIVMPLVF
VSILSAIARINQTRSLGKVSVGVLSTLLITTAISAAIGIAMVHLFDVSAAGLIVGDRELAAQGKVLDKAGQVSNLTVPAM
LVSFIPKNPFADLTGANPTSIISVVIFSALLGVAALSLGKEDQALGERIAQGVETLNKLVMRLVRFVIRLTPYGVFALMI
KMAATSKWADIVNLGNFIVASYAAIALMFVVHGILLFFVKVNPVDYYKKVLPTLSFAFTSRSSAATIPLNIETQTAKLGN
NNVIANFAATFGATIGQNGCGGIYPAMLAVMVAPMVGIDPFSFSYILTLIFVVAISSFGIAGVGGGATFAAIVVLSTLGL
PLELIGLLISIEPIIDMGRTALNVNGAMVAGTITDRLLNK

Sequences:

>Translated_440_residues
MLLVNLAIFIAFLLLLAQLYRKTEKLGQTVFIGLLLGLLFGAVLQSAFEKPLLDKTLDWINVVSNGYVRLLQMIVMPLVF
VSILSAIARINQTRSLGKVSVGVLSTLLITTAISAAIGIAMVHLFDVSAAGLIVGDRELAAQGKVLDKAGQVSNLTVPAM
LVSFIPKNPFADLTGANPTSIISVVIFSALLGVAALSLGKEDQALGERIAQGVETLNKLVMRLVRFVIRLTPYGVFALMI
KMAATSKWADIVNLGNFIVASYAAIALMFVVHGILLFFVKVNPVDYYKKVLPTLSFAFTSRSSAATIPLNIETQTAKLGN
NNVIANFAATFGATIGQNGCGGIYPAMLAVMVAPMVGIDPFSFSYILTLIFVVAISSFGIAGVGGGATFAAIVVLSTLGL
PLELIGLLISIEPIIDMGRTALNVNGAMVAGTITDRLLNK
>Mature_440_residues
MLLVNLAIFIAFLLLLAQLYRKTEKLGQTVFIGLLLGLLFGAVLQSAFEKPLLDKTLDWINVVSNGYVRLLQMIVMPLVF
VSILSAIARINQTRSLGKVSVGVLSTLLITTAISAAIGIAMVHLFDVSAAGLIVGDRELAAQGKVLDKAGQVSNLTVPAM
LVSFIPKNPFADLTGANPTSIISVVIFSALLGVAALSLGKEDQALGERIAQGVETLNKLVMRLVRFVIRLTPYGVFALMI
KMAATSKWADIVNLGNFIVASYAAIALMFVVHGILLFFVKVNPVDYYKKVLPTLSFAFTSRSSAATIPLNIETQTAKLGN
NNVIANFAATFGATIGQNGCGGIYPAMLAVMVAPMVGIDPFSFSYILTLIFVVAISSFGIAGVGGGATFAAIVVLSTLGL
PLELIGLLISIEPIIDMGRTALNVNGAMVAGTITDRLLNK

Specific function: Unknown

COG id: COG1823

COG function: function code R; Predicted Na+/dicarboxylate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI21314632, Length=414, Percent_Identity=25.6038647342995, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI223468564, Length=253, Percent_Identity=26.8774703557312, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI223468566, Length=253, Percent_Identity=26.8774703557312, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI5032093, Length=385, Percent_Identity=25.1948051948052, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI194239697, Length=268, Percent_Identity=26.865671641791, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI40254478, Length=467, Percent_Identity=23.5546038543897, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI169790839, Length=267, Percent_Identity=25.4681647940075, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI66773030, Length=264, Percent_Identity=25.3787878787879, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4827012, Length=271, Percent_Identity=25.830258302583, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788024, Length=442, Percent_Identity=55.8823529411765, Blast_Score=446, Evalue=1e-126,
Organism=Escherichia coli, GI1790514, Length=426, Percent_Identity=23.943661971831, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789947, Length=411, Percent_Identity=24.0875912408759, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71983106, Length=404, Percent_Identity=25, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71983099, Length=404, Percent_Identity=25, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193206505, Length=451, Percent_Identity=24.390243902439, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193206654, Length=453, Percent_Identity=23.6203090507726, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17537407, Length=426, Percent_Identity=23.0046948356808, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541374, Length=413, Percent_Identity=22.5181598062954, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71996953, Length=457, Percent_Identity=21.6630196936543, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583025, Length=435, Percent_Identity=24.1379310344828, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17137668, Length=435, Percent_Identity=24.1379310344828, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583023, Length=435, Percent_Identity=24.1379310344828, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1154_HAEIN (P45079)

Other databases:

- EMBL:   L42023
- PIR:   D64186
- RefSeq:   NP_439312.1
- ProteinModelPortal:   P45079
- GeneID:   950771
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1154
- NMPDR:   fig|71421.1.peg.1107
- TIGR:   HI_1154
- HOGENOM:   HBG739804
- OMA:   AWVMRLV
- ProtClustDB:   CLSK870057
- BioCyc:   HINF71421:HI_1154-MONOMER
- InterPro:   IPR001991
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 46492; Mature: 46492

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd085bb8)-; HASH(0xdc4f5cc)-; HASH(0xd7dc47c)-; HASH(0xc29368c)-; HASH(0xdbaca74)-; HASH(0xdf7e224)-; HASH(0xc92af20)-; HASH(0xe23fa50)-; HASH(0xdc1571c)-; HASH(0xde13470)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEECCCCEEEHHHHHHHHCH
>Mature Secondary Structure
MLLVNLAIFIAFLLLLAQLYRKTEKLGQTVFIGLLLGLLFGAVLQSAFEKPLLDKTLDWI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
NVVSNGYVRLLQMIVMPLVFVSILSAIARINQTRSLGKVSVGVLSTLLITTAISAAIGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVHLFDVSAAGLIVGDRELAAQGKVLDKAGQVSNLTVPAMLVSFIPKNPFADLTGANPTS
HHHHHHHCCCCEEECCHHHHHCCCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHH
IISVVIFSALLGVAALSLGKEDQALGERIAQGVETLNKLVMRLVRFVIRLTPYGVFALMI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KMAATSKWADIVNLGNFIVASYAAIALMFVVHGILLFFVKVNPVDYYKKVLPTLSFAFTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
RSSAATIPLNIETQTAKLGNNNVIANFAATFGATIGQNGCGGIYPAMLAVMVAPMVGIDP
CCCCEEEEEEEEHHHHCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
FSFSYILTLIFVVAISSFGIAGVGGGATFAAIVVLSTLGLPLELIGLLISIEPIIDMGRT
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
ALNVNGAMVAGTITDRLLNK
EEECCCCEEEHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800