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The map label for this gene is ftsZ

Identifier: 16273069

GI number: 16273069

Start: 1212021

End: 1213286

Strand: Direct

Name: ftsZ

Synonym: HI1143

Alternate gene names: 16273069

Gene position: 1212021-1213286 (Clockwise)

Preceding gene: 16273068

Following gene: 16273070

Centisome position: 66.23

GC content: 41.0

Gene sequence:

>1266_bases
ATGCTATACCCAGAGTACCCTGAGTACGATAATTTTAACGAATCCGGCGCACTGATCAAAGTCGTAGGTGTAGGCGGTGG
CGGTGGCAATGCCGTAAACCATATGGTAATGAATATGGTAAAACAAGAAATGGGCGGAACCTTTGTTGGCGAAAGTTCAT
TAACATCAGAGGAACACGGTCGCATAGTATTTTATGCCGTCAATACTGATGCTCAAGCATTGCGTAAAAGTCAAGTTCAA
CAGACCGTACAAATTGGTGGAGAAACAACCAAAGGTTTAGGTGCTGGGGCAAATCCGAATATTGGTCGTAAGGCAGCTGA
AGATGATCAGGATGAAATCCGCAAAATGCTTGAAGGTGCCGATATGGTCTTTATTGCAGCAGGTATGGGCGGCGGCACAG
GTACGGGTGCGGCACCTGTTGTTGCTAAAATTGCTAAAGAACTCGGTATTTTGACTGTTGCTGTAGTGACTAAACCTTTT
ACCTTTGAAGGCAAAAAACGTATGCAATTTGCAGAGCTTGGTATTAAAGATTTATCCCAATATGTTGATTCAATGATTAT
TATTCCGAATCAACAAATCCAAAAAGTTCTCCCTAAAAATGCTAAATTAATTGATGCTTTTGCTGCTGCAAACGACGTAT
TGCGTAATTCTGTAATGGGAATTTCAGATATGATTACCTCTCCTGGTTTAATTAACGTGGACTTCGCTGATGTAAGAACG
GTAATGTCAGTTCAAGGGCAAGCTATGATTGGTTTTGGTTCAGCTGTGGGAGAACCCGGTGCAGGTAGAGCAGAAGAGGC
AGCTCGTCTTGCAGTACGCAATGATCTTCTAGAAAAAATCGATCTTTCTAACGCTCAAGGAATTTTAGTTAATATTACTG
CTGGAATGGATTTAGTTTTTGAAGAGTTTAACATTATAGGTGAGACAATAGGTAGTTTTGCTTCTGAAGAAGCTACAGTT
GTTGTTGGTACGAGTTTAGTGCCTGAGATGAGCGATGAAATTCGTGTAACTATTGTGGCAACTGGTCTCGGTGAAATTGC
AGGAAATGAACCAATTCAGGTTGTTCGTCAAGGGCTTTCTACGCAGAATATTGAAGGTGAAGGACGTGTAAACATTGTTC
CTGAACTTCATCGTCGTGAATCTGTTGAAGTGTCAAGAACTGCATCAGAAGAATATCAACGGCCGTTAGATAAACCGATT
ACAGATCGCTTGGAAGCATTTAAGAAAAATAATTTCTTTAATCCTGCACAGCGTGAAGAAAATTAA

Upstream 100 bases:

>100_bases
TGCGGTCAGAATTTTGATTATTTTAATTTTTCATCTACAATAAAGGGAATTTATATTTTATATATTTAGTCAGCTTATCT
GGCAGTAACGGAGAACATCA

Downstream 100 bases:

>100_bases
TAAGTTTCAGAAAATACCTAGTAAATGAAGGTAGTAGAATGATTAAACAAAGAACATTAAAACAAAGTATTAAAGTTACA
GGCGTTGGCTTGCATAGCGG

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MLYPEYPEYDNFNESGALIKVVGVGGGGGNAVNHMVMNMVKQEMGGTFVGESSLTSEEHGRIVFYAVNTDAQALRKSQVQ
QTVQIGGETTKGLGAGANPNIGRKAAEDDQDEIRKMLEGADMVFIAAGMGGGTGTGAAPVVAKIAKELGILTVAVVTKPF
TFEGKKRMQFAELGIKDLSQYVDSMIIIPNQQIQKVLPKNAKLIDAFAAANDVLRNSVMGISDMITSPGLINVDFADVRT
VMSVQGQAMIGFGSAVGEPGAGRAEEAARLAVRNDLLEKIDLSNAQGILVNITAGMDLVFEEFNIIGETIGSFASEEATV
VVGTSLVPEMSDEIRVTIVATGLGEIAGNEPIQVVRQGLSTQNIEGEGRVNIVPELHRRESVEVSRTASEEYQRPLDKPI
TDRLEAFKKNNFFNPAQREEN

Sequences:

>Translated_421_residues
MLYPEYPEYDNFNESGALIKVVGVGGGGGNAVNHMVMNMVKQEMGGTFVGESSLTSEEHGRIVFYAVNTDAQALRKSQVQ
QTVQIGGETTKGLGAGANPNIGRKAAEDDQDEIRKMLEGADMVFIAAGMGGGTGTGAAPVVAKIAKELGILTVAVVTKPF
TFEGKKRMQFAELGIKDLSQYVDSMIIIPNQQIQKVLPKNAKLIDAFAAANDVLRNSVMGISDMITSPGLINVDFADVRT
VMSVQGQAMIGFGSAVGEPGAGRAEEAARLAVRNDLLEKIDLSNAQGILVNITAGMDLVFEEFNIIGETIGSFASEEATV
VVGTSLVPEMSDEIRVTIVATGLGEIAGNEPIQVVRQGLSTQNIEGEGRVNIVPELHRRESVEVSRTASEEYQRPLDKPI
TDRLEAFKKNNFFNPAQREEN
>Mature_421_residues
MLYPEYPEYDNFNESGALIKVVGVGGGGGNAVNHMVMNMVKQEMGGTFVGESSLTSEEHGRIVFYAVNTDAQALRKSQVQ
QTVQIGGETTKGLGAGANPNIGRKAAEDDQDEIRKMLEGADMVFIAAGMGGGTGTGAAPVVAKIAKELGILTVAVVTKPF
TFEGKKRMQFAELGIKDLSQYVDSMIIIPNQQIQKVLPKNAKLIDAFAAANDVLRNSVMGISDMITSPGLINVDFADVRT
VMSVQGQAMIGFGSAVGEPGAGRAEEAARLAVRNDLLEKIDLSNAQGILVNITAGMDLVFEEFNIIGETIGSFASEEATV
VVGTSLVPEMSDEIRVTIVATGLGEIAGNEPIQVVRQGLSTQNIEGEGRVNIVPELHRRESVEVSRTASEEYQRPLDKPI
TDRLEAFKKNNFFNPAQREEN

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family

Homologues:

Organism=Escherichia coli, GI1786284, Length=315, Percent_Identity=62.8571428571429, Blast_Score=345, Evalue=3e-96,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FTSZ_HAEIN (P45069)

Other databases:

- EMBL:   L42023
- PIR:   I64185
- RefSeq:   NP_439301.1
- ProteinModelPortal:   P45069
- SMR:   P45069
- GeneID:   950290
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1143
- NMPDR:   fig|71421.1.peg.1096
- TIGR:   HI_1143
- HOGENOM:   HBG478075
- OMA:   VNIVPEL
- ProtClustDB:   PRK09330
- BioCyc:   HINF71421:HI_1143-MONOMER
- GO:   GO:0005737
- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008
- Gene3D:   G3DSA:3.30.1330.20
- Gene3D:   G3DSA:3.40.50.1440
- PRINTS:   PR00423
- SMART:   SM00864
- SMART:   SM00865
- TIGRFAMs:   TIGR00065

Pfam domain/function: PF00091 Tubulin; SSF55307 Tub_FtsZ_C; SSF52490 Tubulin_FtsZ

EC number: NA

Molecular weight: Translated: 45023; Mature: 45023

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS01134 FTSZ_1; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPEYPEYDNFNESGALIKVVGVGGGGGNAVNHMVMNMVKQEMGGTFVGESSLTSEEHG
CCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCC
RIVFYAVNTDAQALRKSQVQQTVQIGGETTKGLGAGANPNIGRKAAEDDQDEIRKMLEGA
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
DMVFIAAGMGGGTGTGAAPVVAKIAKELGILTVAVVTKPFTFEGKKRMQFAELGIKDLSQ
CEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCEECCHHHHHHHHCCHHHHHH
YVDSMIIIPNQQIQKVLPKNAKLIDAFAAANDVLRNSVMGISDMITSPGLINVDFADVRT
HHCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHH
VMSVQGQAMIGFGSAVGEPGAGRAEEAARLAVRNDLLEKIDLSNAQGILVNITAGMDLVF
HHHCCCCEEEEECHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHH
EEFNIIGETIGSFASEEATVVVGTSLVPEMSDEIRVTIVATGLGEIAGNEPIQVVRQGLS
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEECCHHHCCCCHHHHHHHCCC
TQNIEGEGRVNIVPELHRRESVEVSRTASEEYQRPLDKPITDRLEAFKKNNFFNPAQREE
CCCCCCCCCEEECCHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHCCC
N
C
>Mature Secondary Structure
MLYPEYPEYDNFNESGALIKVVGVGGGGGNAVNHMVMNMVKQEMGGTFVGESSLTSEEHG
CCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCC
RIVFYAVNTDAQALRKSQVQQTVQIGGETTKGLGAGANPNIGRKAAEDDQDEIRKMLEGA
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
DMVFIAAGMGGGTGTGAAPVVAKIAKELGILTVAVVTKPFTFEGKKRMQFAELGIKDLSQ
CEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCEECCHHHHHHHHCCHHHHHH
YVDSMIIIPNQQIQKVLPKNAKLIDAFAAANDVLRNSVMGISDMITSPGLINVDFADVRT
HHCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHH
VMSVQGQAMIGFGSAVGEPGAGRAEEAARLAVRNDLLEKIDLSNAQGILVNITAGMDLVF
HHHCCCCEEEEECHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHH
EEFNIIGETIGSFASEEATVVVGTSLVPEMSDEIRVTIVATGLGEIAGNEPIQVVRQGLS
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEECCHHHCCCCHHHHHHHCCC
TQNIEGEGRVNIVPELHRRESVEVSRTASEEYQRPLDKPITDRLEAFKKNNFFNPAQREE
CCCCCCCCCEEECCHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800