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The map label for this gene is talB [H]

Identifier: 16273050

GI number: 16273050

Start: 1192230

End: 1193183

Strand: Direct

Name: talB [H]

Synonym: HI1125

Alternate gene names: 16273050

Gene position: 1192230-1193183 (Clockwise)

Preceding gene: 16273044

Following gene: 16273055

Centisome position: 65.14

GC content: 38.47

Gene sequence:

>954_bases
ATGACAACACAGTTAGATTCACTTCGTAATATGACCGTCGTCGTAGCTGATACTGGCGATATTGATGCAATCAAAAAATA
CCAACCACAAGATGCAACAACAAACCCATCTTTAATTTTAAGTGCTTCAGCATTACCACAATACGCCCCATTAATTGATG
AAGCGGTAGCTTATGCAAAAGCACAAAGTGCAGACAAAGCACAACAATTAATTGATGCTGAAGATAAATTAGCGGTAAAC
ATCGGCTTAGAAATTTTAAAAATTGTTCCAGGACGCATTTCAACAGAAGTAGATGCTCGCCTTTCTTACGATACCCAAGC
AACGGTTGAAAAAGCGCGTAAATTAATTGCACTTTATAATGCAGCAGGCATCTCAAATGATCGTATTTTGATTAAAATCG
CTTCCACATGGCAAGGTATCCGAGCTGCAGAAATCCTTGAAAAAGAAGGCATTAACTGTAACTTAACCTTATTATTCTCT
GAAGCGCAAGCTCGTGCTTGTGCAGAAGCGGGCGTTTACTTAATTTCTCCATTTGTAGGTCGTATTTTAGACTGGTACAA
AGCAAATTCAGACAAAAAAGAATATGCGCCAGCAGAAGATCCAGGCGTTATTTCTGTCACCAAAATCTATAATTACTACA
AAGAATATGGCTACAACACAGTTGTGATGGGCGCAAGTTTCCGTAATGTAGGTGAAATTACTGAACTTGCAGGTTGCGAT
CGTTTAACCATTGCACCAGCATTACTGAAAGAATTACAAGAAAATTCAACCGCACTTGTACGCAAATTAGAATACAAAGG
CGAAGTAAAAGCGAAACCACAACCATTAACAGAAGCTGAGTTCTACTGGCAACATAACAGCGATGCTATGGCTGTTGAAA
AATTAGCAGAGGGTATTCGTAAATTTGCTATTGACCAAGAAAAATTGGAAACCATGCTTTCAGCAAAACTTTAA

Upstream 100 bases:

>100_bases
TTCCTATTGTAAATATTTTCCTACATAAATTACCCTTTTAATGCTAATTGTGCTATCGTAACCTGATTAGATTTAAACAA
GTCCATTCAAGGAGAATACA

Downstream 100 bases:

>100_bases
TCCATCATTCAATATAAAAAATAACCGCACTTCAATCTGCTCTTGAAATAGTTAAAGAAAATATTTAACTAATTTGGGTG
CAGATTTTTTATTTATTAAG

Product: transaldolase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTTQLDSLRNMTVVVADTGDIDAIKKYQPQDATTNPSLILSASALPQYAPLIDEAVAYAKAQSADKAQQLIDAEDKLAVN
IGLEILKIVPGRISTEVDARLSYDTQATVEKARKLIALYNAAGISNDRILIKIASTWQGIRAAEILEKEGINCNLTLLFS
EAQARACAEAGVYLISPFVGRILDWYKANSDKKEYAPAEDPGVISVTKIYNYYKEYGYNTVVMGASFRNVGEITELAGCD
RLTIAPALLKELQENSTALVRKLEYKGEVKAKPQPLTEAEFYWQHNSDAMAVEKLAEGIRKFAIDQEKLETMLSAKL

Sequences:

>Translated_317_residues
MTTQLDSLRNMTVVVADTGDIDAIKKYQPQDATTNPSLILSASALPQYAPLIDEAVAYAKAQSADKAQQLIDAEDKLAVN
IGLEILKIVPGRISTEVDARLSYDTQATVEKARKLIALYNAAGISNDRILIKIASTWQGIRAAEILEKEGINCNLTLLFS
EAQARACAEAGVYLISPFVGRILDWYKANSDKKEYAPAEDPGVISVTKIYNYYKEYGYNTVVMGASFRNVGEITELAGCD
RLTIAPALLKELQENSTALVRKLEYKGEVKAKPQPLTEAEFYWQHNSDAMAVEKLAEGIRKFAIDQEKLETMLSAKL
>Mature_316_residues
TTQLDSLRNMTVVVADTGDIDAIKKYQPQDATTNPSLILSASALPQYAPLIDEAVAYAKAQSADKAQQLIDAEDKLAVNI
GLEILKIVPGRISTEVDARLSYDTQATVEKARKLIALYNAAGISNDRILIKIASTWQGIRAAEILEKEGINCNLTLLFSE
AQARACAEAGVYLISPFVGRILDWYKANSDKKEYAPAEDPGVISVTKIYNYYKEYGYNTVVMGASFRNVGEITELAGCDR
LTIAPALLKELQENSTALVRKLEYKGEVKAKPQPLTEAEFYWQHNSDAMAVEKLAEGIRKFAIDQEKLETMLSAKL

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway [H]

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5803187, Length=320, Percent_Identity=60.3125, Blast_Score=387, Evalue=1e-108,
Organism=Escherichia coli, GI1786189, Length=314, Percent_Identity=78.9808917197452, Blast_Score=516, Evalue=1e-148,
Organism=Escherichia coli, GI1788807, Length=315, Percent_Identity=63.4920634920635, Blast_Score=420, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI25153750, Length=316, Percent_Identity=57.5949367088608, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25153752, Length=165, Percent_Identity=53.3333333333333, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17570473, Length=97, Percent_Identity=46.3917525773196, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323386, Length=299, Percent_Identity=61.2040133779264, Blast_Score=321, Evalue=9e-89,
Organism=Saccharomyces cerevisiae, GI6321480, Length=322, Percent_Identity=52.1739130434783, Blast_Score=318, Evalue=7e-88,
Organism=Drosophila melanogaster, GI45549185, Length=316, Percent_Identity=60.7594936708861, Blast_Score=391, Evalue=1e-109,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225 [H]

Pfam domain/function: PF00923 Transaldolase [H]

EC number: =2.2.1.2 [H]

Molecular weight: Translated: 34905; Mature: 34774

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01054 TRANSALDOLASE_1 ; PS00958 TRANSALDOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQLDSLRNMTVVVADTGDIDAIKKYQPQDATTNPSLILSASALPQYAPLIDEAVAYAK
CCCCHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
AQSADKAQQLIDAEDKLAVNIGLEILKIVPGRISTEVDARLSYDTQATVEKARKLIALYN
HHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCCCCCHHCEECCCHHHHHHHHHHHHHHHH
AAGISNDRILIKIASTWQGIRAAEILEKEGINCNLTLLFSEAQARACAEAGVYLISPFVG
HCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHH
RILDWYKANSDKKEYAPAEDPGVISVTKIYNYYKEYGYNTVVMGASFRNVGEITELAGCD
HHHHHHHCCCCCHHCCCCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCC
RLTIAPALLKELQENSTALVRKLEYKGEVKAKPQPLTEAEFYWQHNSDAMAVEKLAEGIR
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
KFAIDQEKLETMLSAKL
HHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TTQLDSLRNMTVVVADTGDIDAIKKYQPQDATTNPSLILSASALPQYAPLIDEAVAYAK
CCCHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
AQSADKAQQLIDAEDKLAVNIGLEILKIVPGRISTEVDARLSYDTQATVEKARKLIALYN
HHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCCCCCHHCEECCCHHHHHHHHHHHHHHHH
AAGISNDRILIKIASTWQGIRAAEILEKEGINCNLTLLFSEAQARACAEAGVYLISPFVG
HCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHH
RILDWYKANSDKKEYAPAEDPGVISVTKIYNYYKEYGYNTVVMGASFRNVGEITELAGCD
HHHHHHHCCCCCHHCCCCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCC
RLTIAPALLKELQENSTALVRKLEYKGEVKAKPQPLTEAEFYWQHNSDAMAVEKLAEGIR
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
KFAIDQEKLETMLSAKL
HHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]