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The map label for this gene is comM

Identifier: 16273042

GI number: 16273042

Start: 1183115

End: 1184644

Strand: Reverse

Name: comM

Synonym: HI1117

Alternate gene names: 16273042

Gene position: 1184644-1183115 (Counterclockwise)

Preceding gene: 16273043

Following gene: 16273040

Centisome position: 64.73

GC content: 43.01

Gene sequence:

>1530_bases
ATGTCCCTTGCTATTGTTTACAGCCGTGCCTCTATGGGCGTGCAAGCGCCGCTTGTCACCATTGAGGTGCATTTAAGCAA
CGGAAAACCAGGATTTACACTTGTTGGTTTGCCAGAAAAAACCGTGAAAGAGGCACAAGATAGGGTGCGTAGTGCGTTGA
TGAATGCACAATTTAAATACCCAGCCAAGCGTATCACTGTAAATCTTGCACCTGCGGATTTACCGAAAGAAGGCGGAAGA
TTTGATTTGCCTATCGCCATCGGAATTTTAGCCGCATCAGATCAGCTTGATGCGAGCCACTTAAAGCAATTTGAATTTGT
GGCAGAGCTTGCGCTGACGGGCCAATTGCGTGGCGTACATGGTGTGATTCCCGCTATTCTTGCAGCGCAAAAGTCAAAGC
GAGAGTTAATTATTGCGAAACAAAATGCTAATGAAGCCTCGCTCGTGTCTGATCAAAATACTTATTTTGCTCAAACGCTT
TTAGATGTAGTGCAATTTCTCAATGGTCAGGAAAAATTACCACTCGCCACTGAAATTGTGAAAGAAAGTGCGGTAAATTT
TTCAGGTAAAAATACGTTAGATTTAACGGATATTATCGGACAACAGCACGCTAAACGAGCATTGACCATTGCCGCAGCGG
GGCAGCATAATTTGCTCTTTCTTGGCCCACCGGGTACAGGGAAAACCATGTTAGCCAGCCGTTTGACAGGGCTTTTACCT
GAAATGACAGATTTAGAAGCGATAGAAACGGCATCTGTAACGAGTTTAGTTCAAAACGAGTTAAATTTTCATAATTGGAA
GCAACGTCCTTTTCGTGCACCACATCATAGTGCATCAATGCCTGCTTTAGTTGGTGGCGGAACGATCCCTAAACCTGGCG
AAATATCCTTAGCAACAAATGGGGTACTTTTTCTTGATGAACTTCCAGAATTTGAGCGAAAAGTGTTAGATGCACTACGT
CAGCCTTTGGAAAGTGGTGAGATTATTATTTCTCGTGCTAATGCCAAAATTCAATTTCCGGCTCGTTTTCAATTAGTGGC
AGCAATGAATCCAAGTCCGACAGGCCATTATACAGGAACACATAACCGCACTTCACCACAGCAAATTATGCGTTATTTGA
ATCGACTTTCAGGGCCATTTTTAGATCGTTTTGATTTATCTATTGAAGTGCCTTTACTGCCACAAGGTAGCTTGCAAAAT
ACGGGCGATCGTGGCGAAACCAGCGCGCAAGTTCGTGAAAAAGTGTTAAAAGTACGTGAGATTCAAATGGAAAGAGCGGG
GAAAATCAACGCTTATTTGAACAGTAAAGAGATTGAGCGTGATTGCAAGTTAAATGATAAAGATGCCTTTTTCCTTGAAA
AAGCACTGAATAAACTGGGGCTTTCTGTTCGGGCTTATCATCGTATTTTGAAAGTTTCTCGAACCATTGCCGATCTACAA
GGAGAACAACAAATTTTTCAACCGCACTTGGCGGAGGCCTTGGGCTATCGAGCAATGGTTCGTTTGCTGCAGAAATTGTC
GAATATGTAA

Upstream 100 bases:

>100_bases
GATCTAGATCGCAAAAAAAGCACGGAATGAATGATTTCATTACGTGCTTTTTTTATAGTGCAAAAACTATCTTCATTTTT
ACCGCACTTTAAGGATTATC

Downstream 100 bases:

>100_bases
AAACGCGTGGAAAGAATACCACGCGTGAAAGGATTAGTAAGTGCTTTGAGTGTCTTGAGTACCGCTAATAATCGCAATGC
CAGCGCTTGCACCAATGCGA

Product: competence protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MSLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKYPAKRITVNLAPADLPKEGGR
FDLPIAIGILAASDQLDASHLKQFEFVAELALTGQLRGVHGVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTL
LDVVQFLNGQEKLPLATEIVKESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLP
EMTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATNGVLFLDELPEFERKVLDALR
QPLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGTHNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQN
TGDRGETSAQVREKVLKVREIQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQ
GEQQIFQPHLAEALGYRAMVRLLQKLSNM

Sequences:

>Translated_509_residues
MSLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKYPAKRITVNLAPADLPKEGGR
FDLPIAIGILAASDQLDASHLKQFEFVAELALTGQLRGVHGVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTL
LDVVQFLNGQEKLPLATEIVKESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLP
EMTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATNGVLFLDELPEFERKVLDALR
QPLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGTHNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQN
TGDRGETSAQVREKVLKVREIQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQ
GEQQIFQPHLAEALGYRAMVRLLQKLSNM
>Mature_508_residues
SLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKYPAKRITVNLAPADLPKEGGRF
DLPIAIGILAASDQLDASHLKQFEFVAELALTGQLRGVHGVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTLL
DVVQFLNGQEKLPLATEIVKESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLPE
MTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATNGVLFLDELPEFERKVLDALRQ
PLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGTHNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQNT
GDRGETSAQVREKVLKVREIQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQG
EQQIFQPHLAEALGYRAMVRLLQKLSNM

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily

Homologues:

Organism=Escherichia coli, GI145693202, Length=511, Percent_Identity=58.9041095890411, Blast_Score=613, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COMM_HAEIN (P45049)

Other databases:

- EMBL:   L42023
- PIR:   I64183
- RefSeq:   NP_439274.1
- ProteinModelPortal:   P45049
- SMR:   P45049
- GeneID:   950645
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1117
- NMPDR:   fig|71421.1.peg.1073
- TIGR:   HI_1117
- HOGENOM:   HBG665393
- OMA:   NAGFEFP
- ProtClustDB:   CLSK870513
- BioCyc:   HINF71421:HI_1117-MONOMER
- GO:   GO:0015979
- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568
- PRINTS:   PR01657
- SMART:   SM00382
- TIGRFAMs:   TIGR00368

Pfam domain/function: PF01078 Mg_chelatase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 55916; Mature: 55785

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKY
CCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCC
PAKRITVNLAPADLPKEGGRFDLPIAIGILAASDQLDASHLKQFEFVAELALTGQLRGVH
CCEEEEEEECCCCCCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHH
GVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTLLDVVQFLNGQEKLPLATEIV
HHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
KESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLP
HHHHCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCC
EMTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEC
GVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGT
CEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCCCCCCC
HNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQNTGDRGETSAQVREKVLKVRE
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQ
HHHHHCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GEQQIFQPHLAEALGYRAMVRLLQKLSNM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKY
CEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCC
PAKRITVNLAPADLPKEGGRFDLPIAIGILAASDQLDASHLKQFEFVAELALTGQLRGVH
CCEEEEEEECCCCCCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHH
GVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTLLDVVQFLNGQEKLPLATEIV
HHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
KESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLP
HHHHCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCC
EMTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEC
GVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGT
CEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCCCCCCC
HNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQNTGDRGETSAQVREKVLKVRE
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQ
HHHHHCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GEQQIFQPHLAEALGYRAMVRLLQKLSNM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884