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The map label for this gene is xylH

Identifier: 16273034

GI number: 16273034

Start: 1173984

End: 1175111

Strand: Reverse

Name: xylH

Synonym: HI1109

Alternate gene names: 16273034

Gene position: 1175111-1173984 (Counterclockwise)

Preceding gene: 16273035

Following gene: 16273033

Centisome position: 64.21

GC content: 38.45

Gene sequence:

>1128_bases
ATGTTTAAGTTAAAATCCGTAAATTTACAAGTTTACATTATGTTAATAGCTATTGCAGTCATTATGGCATTCTTTAGTGT
TGCTACTGATGGCGCTTATTTAAGTGCAAGAAATATTTCTAACTTGTTACGCCAAACYTCAATTACTGGCAWTCTTGCAA
TTGGAATGGTTTTTGTCATTATTTCTGCTGAAATTGACTTATCTGTTGGTTCACTTATGGGCCTACTGGGCGGATTTGCA
GCTATTGCCGATGTTTGGTGGGGCTTCCCATTACCTGTAACTATTATTGCAACAATTGCTCTTGGTTTAATTTTTGGTAT
TTGGAATGGTTGGTGGGTGGCTTATCGCAAAGTGCCATCCTTCATTGTTACACTTGCAGGTTATCTCGCATTTCGTGGAA
TTTTGATTGGTTTGACTAATGGTACAACTGTATCTCCTATTAGTGGAACTATGACAGTTATTGGGCAAGGTTATTTATCA
GATATTGCAGGGGTTATCTTAGGTGGTATTGCAGTTATTGGATTTGTTCTTTGGGGAAATTATCAACGTAGAAGTCGCCA
GCAGCTTCAGCTGGAAGTGTCTGCATTATCAAAAGATTTTACGAAATATGCTTTGTTTGCAGTAATTGTATTAGGAGCAA
TTTATTTACTTAATGATTATCGTGGCATTCCATTTCCTGTTTTAGTACTGGCAGTTCTTGCAATCTTAGGGTTATTCCTC
TCTCGTAAAACTTCATTCGGCCGCCACGTTTATGCAATTGGTGGCAATATTGATGCGGCAAAATTATCTGGTATCAATGT
AGAGAAAACAAAACTGATTATCTTTGCAATGAATGGTGTGTTAGTTGCAATAGCAGGGTTGATTTTAAGTGCTCGTTTAG
GTGCAGGATCACCATCTGCTGGGCAAAATGCAGAACTAGATGCGATTGCAGCTTGTGTCATTGGAGGGGCAAGCTTAGCT
GGTGGTGTAGGAAGTGTGTTTGGGGTCGTTATTGGCGCACTTATCATCGCATCGCTTGATAATGGTATGAGTATGCTTGA
TGTGCCAACTTTTTGGCAATATATTGTCAAAGGTGGCATTTTGTTACTTGCTGTATGGATAGATACTAGTAATAAGAAAA
AGATGTAA

Upstream 100 bases:

>100_bases
TAGAGTTCTTGTTATGCACCAAGGTAAACTTAAAGCTAGTCTTATCAATACTGCTCTTACTCAAGAACAAGTTATGGAAA
CAGCACTTAAGGAGTAATCT

Downstream 100 bases:

>100_bases
TTATTAATTTTAAACCGTCATTTATAAAATGGCGGTTTTTTAATTTTATAGAAATGGTTACCTAACATACTGCTTTCTAG
ATGATGAAATTTTTCATCTT

Product: D-xylose ABC transporter permease

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MFKLKSVNLQVYIMLIAIAVIMAFFSVATDGAYLSARNISNLLRQTSITGXLAIGMVFVIISAEIDLSVGSLMGLLGGFA
AIADVWWGFPLPVTIIATIALGLIFGIWNGWWVAYRKVPSFIVTLAGYLAFRGILIGLTNGTTVSPISGTMTVIGQGYLS
DIAGVILGGIAVIGFVLWGNYQRRSRQQLQLEVSALSKDFTKYALFAVIVLGAIYLLNDYRGIPFPVLVLAVLAILGLFL
SRKTSFGRHVYAIGGNIDAAKLSGINVEKTKLIIFAMNGVLVAIAGLILSARLGAGSPSAGQNAELDAIAACVIGGASLA
GGVGSVFGVVIGALIIASLDNGMSMLDVPTFWQYIVKGGILLLAVWIDTSNKKKM

Sequences:

>Translated_375_residues
MFKLKSVNLQVYIMLIAIAVIMAFFSVATDGAYLSARNISNLLRQTSITGXLAIGMVFVIISAEIDLSVGSLMGLLGGFA
AIADVWWGFPLPVTIIATIALGLIFGIWNGWWVAYRKVPSFIVTLAGYLAFRGILIGLTNGTTVSPISGTMTVIGQGYLS
DIAGVILGGIAVIGFVLWGNYQRRSRQQLQLEVSALSKDFTKYALFAVIVLGAIYLLNDYRGIPFPVLVLAVLAILGLFL
SRKTSFGRHVYAIGGNIDAAKLSGINVEKTKLIIFAMNGVLVAIAGLILSARLGAGSPSAGQNAELDAIAACVIGGASLA
GGVGSVFGVVIGALIIASLDNGMSMLDVPTFWQYIVKGGILLLAVWIDTSNKKKM
>Mature_375_residues
MFKLKSVNLQVYIMLIAIAVIMAFFSVATDGAYLSARNISNLLRQTSITGXLAIGMVFVIISAEIDLSVGSLMGLLGGFA
AIADVWWGFPLPVTIIATIALGLIFGIWNGWWVAYRKVPSFIVTLAGYLAFRGILIGLTNGTTVSPISGTMTVIGQGYLS
DIAGVILGGIAVIGFVLWGNYQRRSRQQLQLEVSALSKDFTKYALFAVIVLGAIYLLNDYRGIPFPVLVLAVLAILGLFL
SRKTSFGRHVYAIGGNIDAAKLSGINVEKTKLIIFAMNGVLVAIAGLILSARLGAGSPSAGQNAELDAIAACVIGGASLA
GGVGSVFGVVIGALIIASLDNGMSMLDVPTFWQYIVKGGILLLAVWIDTSNKKKM

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily

Homologues:

Organism=Escherichia coli, GI1789992, Length=371, Percent_Identity=69.811320754717, Blast_Score=480, Evalue=1e-137,
Organism=Escherichia coli, GI1788896, Length=372, Percent_Identity=32.258064516129, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1790524, Length=351, Percent_Identity=31.6239316239316, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1790191, Length=153, Percent_Identity=47.0588235294118, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI145693152, Length=156, Percent_Identity=46.7948717948718, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082395, Length=305, Percent_Identity=32.7868852459016, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788471, Length=370, Percent_Identity=31.8918918918919, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693214, Length=310, Percent_Identity=30, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787793, Length=126, Percent_Identity=36.5079365079365, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787794, Length=147, Percent_Identity=31.2925170068027, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLH_HAEIN (P45045)

Other databases:

- EMBL:   L42023
- PIR:   A64183
- RefSeq:   NP_439266.1
- GeneID:   950080
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1109
- NMPDR:   fig|71421.1.peg.1065
- TIGR:   HI_1109
- HOGENOM:   HBG663180
- OMA:   LLAVWID
- ProtClustDB:   CLSK880725
- BioCyc:   HINF71421:HI_1109-MONOMER
- InterPro:   IPR001851

Pfam domain/function: PF02653 BPD_transp_2

EC number: NA

Molecular weight: Translated: 39457; Mature: 39457

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdf4d260)-; HASH(0xdc1099c)-; HASH(0xe03193c)-; HASH(0xe03015c)-; HASH(0xe02b980)-; HASH(0xe031690)-; HASH(0xb3f40a4)-; HASH(0xc2e8d78)-; HASH(0xe02b9b0)-; HASH(0xb1ffc78)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEEEEECCCCCCH
>Mature Secondary Structure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EEEEEEEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800