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The map label for this gene is nhaC

Identifier: 16273033

GI number: 16273033

Start: 1171129

End: 1172535

Strand: Reverse

Name: nhaC

Synonym: HI1107

Alternate gene names: NA

Gene position: 1172535-1171129 (Counterclockwise)

Preceding gene: 16273034

Following gene: 16273032

Centisome position: 64.07

GC content: 35.89

Gene sequence:

>1407_bases
ATGAAAACCACTCATCGCACAAGAATGCCAACAACATTAGAAGCTTTTTCACCAATCATTGTGATGCTATTACTGTTAGG
GCTTGGGTATGCTTTATTTGATTTGCCAGCAGAGCCATTAATGATTATTTCAACGGTATTTGCTGGTTTTTTAGTTTTTA
AATTAGGTCATTGCTATTTAGATATTTTAGATGCCATTTCAGAAAAAATAGCTAAAACAATGCCTGCGCTATTAATTTTA
ATTACTGTAGGATTATTAATTGGAACTTGGATTAGTGGAGGAACAATTCCTATGATGATCTACTACGGACTAAAAGCGAT
ATCACCAGAATATCTTTATGTGACAGCCTTATTCCTTACTGCTATTGTTTCCATTTGTACTGGAACCTCTTGGGGGTCAG
CAGGGACTGTTGGTGTGGCATTTATGGGAGTTGCGATTGGATTAGACGCCAATTTGGCTGCTACGGCAGGTGCTGTGGTC
GCTGGTGCGTATTTTGGAGATAAATTATCGCCATTATCTGATACAACCAATATTGCATCCGCAGCTGCTGGCGTAGATTT
ATATGAGCATATCGCTCACTTACTTTATACAACATTACCATCTTTTATTCTTTCGGCTACTGTCTATGTGGTATATGGTT
TAAACTACGATTTTTCTAATGTAGCGACTCCAGAAAAAGTAAATACAATGATTCATGAGTTAGAGCAAGTTTATCATTTT
AACTTTCTATTACTTATTCCAGTCGCTATTGTATTATGGGGATCTATTACTAAGAAACCGACTATTCCAGTGATGTTATT
ATCAGCATTTATCGCAATTATTAATGCTATCTTAATTCAAAAATTCTCTCTATCTGATGTGATTAATAGTGCAGTTAATG
GATTTGATACCTCAATGATTCACCATACTTCAGTTAGCTCTGATTTAAGTCGTTTGTTGAATCGTGGTGGAATGAACTCA
ATGATGGGAACACTATTAATTTGTTTCTGTGCATTGTCATTTGCAGGTGTATTACAATTGAGCGGTGCATTAACCGTGAT
TATTCAAAAATTACTCACCTTTGTTCATTCAACTCTTTCTTTGATTATTACAACGATTCTTTGCGGTCTAACAATGATTG
GGGTTACTTGTAATGGGCAAATTTCTATTCTAATTCCAGGAGAAATGCTTAAAAATGCGTATGTAGAAAAAGGATTACAT
CCAAAAAATCTAAGTCGAACAGCAGAAGACTCCGCAACAATTATTGAACCTATTTTGCCATGGACTGCCGCAGGTGCATA
TATGGCAGGCACATTAGGTGTTGCAACATTGTCTTATTTACCTTGGGCAATTTTATGTTGGAGCGGTATTATCTTTGCTA
TTATTTATGGTGCAAGTGGAATAGGTATTGCGAAGCTAAAAAAATAA

Upstream 100 bases:

>100_bases
TTCTTTCGTATGAATGTCGCTATGCCTAGAAAAAAATTATTAGAAGCATTGAATCGAATCAAAAATGGGTTTTGTTTATT
AAACAATAGGGAGATTTAAT

Downstream 100 bases:

>100_bases
ATGTGGTATTGGATATAAAAATGGCCAGTTATTCTGGCTATTTTTATCTTGAAGCTAAATATCTTTTCTATTATAACTTA
AATAGCAATTTCCCATAGAT

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKTTHRTRMPTTLEAFSPIIVMLLLLGLGYALFDLPAEPLMIISTVFAGFLVFKLGHCYLDILDAISEKIAKTMPALLIL
ITVGLLIGTWISGGTIPMMIYYGLKAISPEYLYVTALFLTAIVSICTGTSWGSAGTVGVAFMGVAIGLDANLAATAGAVV
AGAYFGDKLSPLSDTTNIASAAAGVDLYEHIAHLLYTTLPSFILSATVYVVYGLNYDFSNVATPEKVNTMIHELEQVYHF
NFLLLIPVAIVLWGSITKKPTIPVMLLSAFIAIINAILIQKFSLSDVINSAVNGFDTSMIHHTSVSSDLSRLLNRGGMNS
MMGTLLICFCALSFAGVLQLSGALTVIIQKLLTFVHSTLSLIITTILCGLTMIGVTCNGQISILIPGEMLKNAYVEKGLH
PKNLSRTAEDSATIIEPILPWTAAGAYMAGTLGVATLSYLPWAILCWSGIIFAIIYGASGIGIAKLKK

Sequences:

>Translated_468_residues
MKTTHRTRMPTTLEAFSPIIVMLLLLGLGYALFDLPAEPLMIISTVFAGFLVFKLGHCYLDILDAISEKIAKTMPALLIL
ITVGLLIGTWISGGTIPMMIYYGLKAISPEYLYVTALFLTAIVSICTGTSWGSAGTVGVAFMGVAIGLDANLAATAGAVV
AGAYFGDKLSPLSDTTNIASAAAGVDLYEHIAHLLYTTLPSFILSATVYVVYGLNYDFSNVATPEKVNTMIHELEQVYHF
NFLLLIPVAIVLWGSITKKPTIPVMLLSAFIAIINAILIQKFSLSDVINSAVNGFDTSMIHHTSVSSDLSRLLNRGGMNS
MMGTLLICFCALSFAGVLQLSGALTVIIQKLLTFVHSTLSLIITTILCGLTMIGVTCNGQISILIPGEMLKNAYVEKGLH
PKNLSRTAEDSATIIEPILPWTAAGAYMAGTLGVATLSYLPWAILCWSGIIFAIIYGASGIGIAKLKK
>Mature_468_residues
MKTTHRTRMPTTLEAFSPIIVMLLLLGLGYALFDLPAEPLMIISTVFAGFLVFKLGHCYLDILDAISEKIAKTMPALLIL
ITVGLLIGTWISGGTIPMMIYYGLKAISPEYLYVTALFLTAIVSICTGTSWGSAGTVGVAFMGVAIGLDANLAATAGAVV
AGAYFGDKLSPLSDTTNIASAAAGVDLYEHIAHLLYTTLPSFILSATVYVVYGLNYDFSNVATPEKVNTMIHELEQVYHF
NFLLLIPVAIVLWGSITKKPTIPVMLLSAFIAIINAILIQKFSLSDVINSAVNGFDTSMIHHTSVSSDLSRLLNRGGMNS
MMGTLLICFCALSFAGVLQLSGALTVIIQKLLTFVHSTLSLIITTILCGLTMIGVTCNGQISILIPGEMLKNAYVEKGLH
PKNLSRTAEDSATIIEPILPWTAAGAYMAGTLGVATLSYLPWAILCWSGIIFAIIYGASGIGIAKLKK

Specific function: Unknown

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1107_HAEIN (Q57007)

Other databases:

- EMBL:   L42023
- PIR:   I64182
- RefSeq:   NP_439264.1
- GeneID:   950734
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1107
- NMPDR:   fig|71421.1.peg.1064
- TIGR:   HI_1107
- HOGENOM:   HBG307651
- OMA:   DQYISII
- ProtClustDB:   CLSK808485
- BioCyc:   HINF71421:HI_1107-MONOMER
- InterPro:   IPR004770
- InterPro:   IPR018461
- TIGRFAMs:   TIGR00931

Pfam domain/function: PF03553 Na_H_antiporter

EC number: NA

Molecular weight: Translated: 49891; Mature: 49891

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd84ea5c)-; HASH(0xe07e728)-; HASH(0xdcd0888)-; HASH(0xd34ae10)-; HASH(0xda75528)-; HASH(0xd056e4c)-; HASH(0xd62b008)-; HASH(0xd390014)-; HASH(0xe112a44)-; HASH(0xd9753f8)-; HASH(0xc24eb2c)-; HASH(0xd09e48c)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTHRTRMPTTLEAFSPIIVMLLLLGLGYALFDLPAEPLMIISTVFAGFLVFKLGHCYL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DILDAISEKIAKTMPALLILITVGLLIGTWISGGTIPMMIYYGLKAISPEYLYVTALFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
AIVSICTGTSWGSAGTVGVAFMGVAIGLDANLAATAGAVVAGAYFGDKLSPLSDTTNIAS
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AAAGVDLYEHIAHLLYTTLPSFILSATVYVVYGLNYDFSNVATPEKVNTMIHELEQVYHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHH
NFLLLIPVAIVLWGSITKKPTIPVMLLSAFIAIINAILIQKFSLSDVINSAVNGFDTSMI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HHTSVSSDLSRLLNRGGMNSMMGTLLICFCALSFAGVLQLSGALTVIIQKLLTFVHSTLS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIITTILCGLTMIGVTCNGQISILIPGEMLKNAYVEKGLHPKNLSRTAEDSATIIEPILP
HHHHHHHHHHHHHCEEECCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCC
WTAAGAYMAGTLGVATLSYLPWAILCWSGIIFAIIYGASGIGIAKLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCH
>Mature Secondary Structure
MKTTHRTRMPTTLEAFSPIIVMLLLLGLGYALFDLPAEPLMIISTVFAGFLVFKLGHCYL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DILDAISEKIAKTMPALLILITVGLLIGTWISGGTIPMMIYYGLKAISPEYLYVTALFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
AIVSICTGTSWGSAGTVGVAFMGVAIGLDANLAATAGAVVAGAYFGDKLSPLSDTTNIAS
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AAAGVDLYEHIAHLLYTTLPSFILSATVYVVYGLNYDFSNVATPEKVNTMIHELEQVYHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHH
NFLLLIPVAIVLWGSITKKPTIPVMLLSAFIAIINAILIQKFSLSDVINSAVNGFDTSMI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HHTSVSSDLSRLLNRGGMNSMMGTLLICFCALSFAGVLQLSGALTVIIQKLLTFVHSTLS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIITTILCGLTMIGVTCNGQISILIPGEMLKNAYVEKGLHPKNLSRTAEDSATIIEPILP
HHHHHHHHHHHHHCEEECCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCC
WTAAGAYMAGTLGVATLSYLPWAILCWSGIIFAIIYGASGIGIAKLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800