Click here to switch to the map view.

The map label for this gene is secA [H]

Identifier: 16272846

GI number: 16272846

Start: 961732

End: 964437

Strand: Direct

Name: secA [H]

Synonym: HI0909

Alternate gene names: 16272846

Gene position: 961732-964437 (Clockwise)

Preceding gene: 16272845

Following gene: 16272847

Centisome position: 52.55

GC content: 40.72

Gene sequence:

>2706_bases
ATGAGCATTTTAACAAGAATTTTTGGTAGTCGTAATGAACGCGTTTTACGTAAATTAAAAAAACAAGTCGTAAAAATTAA
TAAAATGGAGCCTGCTTTTGAGGCATTAAGTGATGATGAATTAAAAGCAAAAACACAAGAGTTTCGTGATCGTTTAAGTG
GTGGCGAAACTTTGCAACAAATTTTACCAGAAGCATTCGCAACGGTACGCGAAGCAAGTAAGCGTGTGCTTGGTATGCGC
CATTTTGATGTTCAGCTTATCGGTGGGATGGTATTGACTAACCGCTGTATCGCAGAAATGCGTACTGGTGAAGGTAAAAC
ATTAACGGCGACTTTGCCTTGTTATTTAATCGCACTTGAAGGTAAAGGCGTTCACGTGGTAACCGTGAATGATTATCTTG
CTCGCCGAGATGCAGAAACAAACCGTCCGTTATTTGAATTTTTAGGCATGAGTGTAGGCGTCAATATTCCTGGTTTATCG
CCAGAAGAAAAACGTGCAGCTTATGCGGCAGATATTACTTATGCAACCAATAGTGAACTTGGTTTTGATTATTTACGTGA
CAACTTAGCCCACTCAAAAGAAGAGCGTTTCCAACGTACTTTAGGCTATGCGTTGGTGGATGAAGTGGATTCTATCTTAA
TCGATGAAGCGCGTACGCCATTGATTATTTCTGGTCAGGCAGAAAACAGTTCAGAGCTTTATATTGCGGTAAATAAATTG
ATCCCAAGTTTAATTAAACAAGAAAAAGAAGATACGGAAGAATATCAAGGAGAGGGCGATTTCACTTTAGATTTGAAATC
TAAACAAGCGCATTTAACCGAACGTGGTCAAGAAAAAGTAGAAGATTGGTTAATTGCACAAGGTTTAATGCCTGAGGGGG
ACTCTTTGTATTCTCCTAGTCGAATTGTATTGCTTCATCACGTTATGGCTGCATTGCGTGCGCACACATTGTTTGAAAAA
GATGTCGATTACATTGTGAAGGACGGTGAAATCGTGATTGTTGATGAACACACTGGTCGTACAATGGCGGGGCGTCGTTG
GTCAGATGGTTTGCACCAAGCCATTGAGGCAAAAGAAGGGGTGGATGTTAAGAGCGAAAACCAAACTGTTGCATCAATTT
CTTACCAAAACTACTTCCGTTTATATGAACGTCTTGCGGGTATGACGGGGACTGCGGATACCGAAGCATTTGAGTTCCAA
CAAATTTATGGCTTGGAAACTGTTGTAATTCCAACAAATCGTCCAATGATTCGTGATGATCGCACTGATGTGATGTTTGA
AAATGAACAATATAAATTTAATGCGATTATTGAAGACATTAAAGATTGTGTAGAACGCCAGCAACCAGTATTAGTGGGGA
CGATTTCAGTCGAAAAATCAGAAGAATTATCTAAAGCGTTAGATAAAGCAGGTATAAAACACAATGTGTTGAATGCGAAA
TTCCACCAACAAGAAGCGGAAATCGTGGCAGAAGCAGGATTTCCTAGCGCAGTGACTATCGCAACGAATATGGCGGGTCG
AGGTACGGATATTATTCTTGGCGGTAACTGGAAAGCGCAGGCTGCCAAATTAGAAAATCCAACTCAAGAACAAATTGAAG
CCCTTAAAGCAGAGTGGGAGAAAAACCACGAAATTGTAATGAAAGCGGGTGGGTTGCATATTATCGGTACAGAGCGTCAC
GAATCTCGCCGTATTGATAACCAGTTGCGCGGTCGTTCTGGGCGTCAAGGTGACCCCGGTTCTTCTCGTTTCTATCTTTC
TTTGGAAGATGGTTTAATGCGCATTTATTTGAATGAGGGTAAGCTCAATTTAATGCGTAAAGCGTTCACGGTAGCAGGCG
AGGCAATGGAGTCGAAAATGTTGGCGAAAGTGATTGCATCTGCTCAAGCAAAAGTTGAGGCGTTCCATTTTGATGGCCGT
AAAAACCTACTTGAATATGATGATGTGGCAAATGACCAACGTCACGCGATTTATGAGCAACGCAATCATTTGCTTGATAA
TGATGATATTTCTGAAACTATCAACGCTATTCGCCACGATGTGTTTAATGGTGTGATTGATCAATATATTCCACCACAAT
CTTTGGAAGAACAATGGGATATTAAAGGGCTTGAAGAACGTTTATCTCAAGAGTTTGGTATGGAATTACCGATTTCTAAT
TGGTTGGAAGAAGATAATAATCTTCACGAAGAAAGTTTGCGCGAACGCATTGTGGAAATTGCAGAAAAGGAATACAAAGA
AAAAGAGGCTTTGGTTGGCGAAGACGCTATGCGCCATTTTGAAAAAGGTGTTATGTTGCAAACCTTAGATGAACTTTGGA
AAGAACACTTAGCTTCGATGGATTATTTACGCCAAGGTATTCATTTACGTGGCTATGCCCAAAAAGATCCAAAACAAGAG
TATAAAAAAGAATCTTTCCGTATGTTTACGGAAATGTTGGATTCTTTAAAACACCAGGTTATCACGGCTTTAACCCGTGT
ACGTGTGCGTACTCAAGAAGAAATGGAAGAAGCTGAACGTGCTCGTCAAGAAATGGCAGCACGTATCAATCAAAATAATT
TACCTGTGGATGAAAATAGTCAGACAACTCAAAATTCAGAGACTGAAGATTATTCAGATCGTCGCATTGGTCGCAACGAG
CCTTGTCCTTGTGGGTCGGGTAAAAAATATAAGCATTGTCACGGCAGTCGTGTGGCACGCCAGTAA

Upstream 100 bases:

>100_bases
TTGCTATTGAAATAGCGATATTTTAAAAAATTATTGTGCATGAAATAAAGTATTTCATAAGCATTTAACTATTTAACTTA
TATATTTAAAAAGAGAAATT

Downstream 100 bases:

>100_bases
TGAACAATCAAAGTGCGGTGATTTTTCACCGCACCTTTTTCATACCTCTACATTGGATAGAAAAATGGATAAAAAAATTA
TACAAGTTGCTGCGGGGATT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 901; Mature: 900

Protein sequence:

>901_residues
MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQILPEAFATVREASKRVLGMR
HFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALEGKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLS
PEEKRAAYAADITYATNSELGFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAENSSELYIAVNKL
IPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPSRIVLLHHVMAALRAHTLFEK
DVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVDVKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQ
QIYGLETVVIPTNRPMIRDDRTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAK
FHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWEKNHEIVMKAGGLHIIGTERH
ESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEGKLNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGR
KNLLEYDDVANDQRHAIYEQRNHLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISN
WLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMRHFEKGVMLQTLDELWKEHLASMDYLRQGIHLRGYAQKDPKQE
YKKESFRMFTEMLDSLKHQVITALTRVRVRTQEEMEEAERARQEMAARINQNNLPVDENSQTTQNSETEDYSDRRIGRNE
PCPCGSGKKYKHCHGSRVARQ

Sequences:

>Translated_901_residues
MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQILPEAFATVREASKRVLGMR
HFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALEGKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLS
PEEKRAAYAADITYATNSELGFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAENSSELYIAVNKL
IPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPSRIVLLHHVMAALRAHTLFEK
DVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVDVKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQ
QIYGLETVVIPTNRPMIRDDRTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAK
FHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWEKNHEIVMKAGGLHIIGTERH
ESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEGKLNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGR
KNLLEYDDVANDQRHAIYEQRNHLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISN
WLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMRHFEKGVMLQTLDELWKEHLASMDYLRQGIHLRGYAQKDPKQE
YKKESFRMFTEMLDSLKHQVITALTRVRVRTQEEMEEAERARQEMAARINQNNLPVDENSQTTQNSETEDYSDRRIGRNE
PCPCGSGKKYKHCHGSRVARQ
>Mature_900_residues
SILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQILPEAFATVREASKRVLGMRH
FDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALEGKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSP
EEKRAAYAADITYATNSELGFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAENSSELYIAVNKLI
PSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPSRIVLLHHVMAALRAHTLFEKD
VDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVDVKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQ
IYGLETVVIPTNRPMIRDDRTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAKF
HQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWEKNHEIVMKAGGLHIIGTERHE
SRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEGKLNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRK
NLLEYDDVANDQRHAIYEQRNHLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISNW
LEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMRHFEKGVMLQTLDELWKEHLASMDYLRQGIHLRGYAQKDPKQEY
KKESFRMFTEMLDSLKHQVITALTRVRVRTQEEMEEAERARQEMAARINQNNLPVDENSQTTQNSETEDYSDRRIGRNEP
CPCGSGKKYKHCHGSRVARQ

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=896, Percent_Identity=68.1919642857143, Blast_Score=1283, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 102588; Mature: 102457

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQ
CCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHH
ILPEAFATVREASKRVLGMRHFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECEEEEEEC
GKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSPEEKRAAYAADITYATNSEL
CCCEEEEEECHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHEEEEEECCCCC
GFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAENSSELYIAVNKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEHHHH
IPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPS
HHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
RIVLLHHVMAALRAHTLFEKDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEG
HHHHHHHHHHHHHHHHHHHHCHHHEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC
VDVKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQIYGLETVVIPTNRPMIRDD
CCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCC
RTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAK
CCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHCHH
FHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCHHHHHCCCCCHHHHHHHHHHHC
KNHEIVMKAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEG
CCCEEEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEECCC
KLNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRKNLLEYDDVANDQRHAIYEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCCCHHHHHHHH
RNHLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISN
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHHH
WLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMRHFEKGVMLQTLDELWKEHLASM
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
DYLRQGIHLRGYAQKDPKQEYKKESFRMFTEMLDSLKHQVITALTRVRVRTQEEMEEAER
HHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQEMAARINQNNLPVDENSQTTQNSETEDYSDRRIGRNEPCPCGSGKKYKHCHGSRVAR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHCC
Q
C
>Mature Secondary Structure 
SILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQ
CHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHH
ILPEAFATVREASKRVLGMRHFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECEEEEEEC
GKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSPEEKRAAYAADITYATNSEL
CCCEEEEEECHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHEEEEEECCCCC
GFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAENSSELYIAVNKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEHHHH
IPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPS
HHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
RIVLLHHVMAALRAHTLFEKDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEG
HHHHHHHHHHHHHHHHHHHHCHHHEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC
VDVKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQIYGLETVVIPTNRPMIRDD
CCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCC
RTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAK
CCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHCHH
FHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCHHHHHCCCCCHHHHHHHHHHHC
KNHEIVMKAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEG
CCCEEEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEECCC
KLNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRKNLLEYDDVANDQRHAIYEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCCCHHHHHHHH
RNHLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISN
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHHH
WLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMRHFEKGVMLQTLDELWKEHLASM
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
DYLRQGIHLRGYAQKDPKQEYKKESFRMFTEMLDSLKHQVITALTRVRVRTQEEMEEAER
HHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQEMAARINQNNLPVDENSQTTQNSETEDYSDRRIGRNEPCPCGSGKKYKHCHGSRVAR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA