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The map label for this gene is ndk [H]

Identifier: 16272816

GI number: 16272816

Start: 929409

End: 929834

Strand: Direct

Name: ndk [H]

Synonym: HI0876

Alternate gene names: 16272816

Gene position: 929409-929834 (Clockwise)

Preceding gene: 30995408

Following gene: 16272821

Centisome position: 50.78

GC content: 36.15

Gene sequence:

>426_bases
GTGATGACAGAAAGAACTTTTTCGATTATTAAACCTGATGTAGTAAAGCGTAATCTAATTGGGGCGATCTTAACTCGTTT
TGAGCAAAATGGCTTTAAAATCATAGCCTCTAAAATGGTACGCTTAACTCGTGAGCAGGCTGAAGGCTTTTATGCAGAGC
ATCAAGGCAAAGAATTTTTTGTGCCTTTAGTTGAATATATGATGTCTTCACCGATAGTGGTTTCTGTTCTTGAAAAAGAA
AATGCAGTGAAAGATTACCGCACTTTGATTGGTACAACGAATCCAGAAACTGCAGCAGAAGGTACAATTCGTAAAGATTT
TGCATTAAGTCAGCGTGAAAACTCAGTTCACGGATCAGATAGTATAGAAAGTGCAAATCGTGAAATTGCTTATTTCTTTA
CTAATTCTGAAATTTTTGAGCGTTAA

Upstream 100 bases:

>100_bases
TCGTAAATCTGGTAGTGATTTATGGTCTGTTGGGGCAACAGGAATTGGTGTGCAAACTTTAGCTAATTTAATGTTATCAA
GATCATTGAAGTAAGGAGAT

Downstream 100 bases:

>100_bases
TTAATAGCAAAAAGCACCTAAAAATTTTAGGTGCTTTTAAATTTTTAATGCTTACAAAATTAGACTTTCTTAAGGTTTAT
AGATGAACTCAATTCCTTCA

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MMTERTFSIIKPDVVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFFVPLVEYMMSSPIVVSVLEKE
NAVKDYRTLIGTTNPETAAEGTIRKDFALSQRENSVHGSDSIESANREIAYFFTNSEIFER

Sequences:

>Translated_141_residues
MMTERTFSIIKPDVVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFFVPLVEYMMSSPIVVSVLEKE
NAVKDYRTLIGTTNPETAAEGTIRKDFALSQRENSVHGSDSIESANREIAYFFTNSEIFER
>Mature_141_residues
MMTERTFSIIKPDVVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFFVPLVEYMMSSPIVVSVLEKE
NAVKDYRTLIGTTNPETAAEGTIRKDFALSQRENSVHGSDSIESANREIAYFFTNSEIFER

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=136, Percent_Identity=47.0588235294118, Blast_Score=132, Evalue=1e-31,
Organism=Homo sapiens, GI66392203, Length=137, Percent_Identity=44.5255474452555, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI66392227, Length=137, Percent_Identity=44.5255474452555, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI66392205, Length=137, Percent_Identity=44.5255474452555, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI4505409, Length=137, Percent_Identity=44.5255474452555, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI66392192, Length=137, Percent_Identity=44.5255474452555, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI4557797, Length=138, Percent_Identity=42.7536231884058, Blast_Score=126, Evalue=7e-30,
Organism=Homo sapiens, GI38045913, Length=138, Percent_Identity=42.7536231884058, Blast_Score=126, Evalue=7e-30,
Organism=Homo sapiens, GI4826862, Length=135, Percent_Identity=40.7407407407407, Blast_Score=114, Evalue=2e-26,
Organism=Homo sapiens, GI5031951, Length=134, Percent_Identity=38.8059701492537, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI37574614, Length=136, Percent_Identity=33.0882352941176, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI7019465, Length=136, Percent_Identity=33.0882352941176, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI4505413, Length=136, Percent_Identity=36.0294117647059, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI148839372, Length=137, Percent_Identity=32.8467153284672, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI30023828, Length=137, Percent_Identity=30.6569343065693, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI1788866, Length=141, Percent_Identity=62.4113475177305, Blast_Score=182, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17506807, Length=136, Percent_Identity=46.3235294117647, Blast_Score=135, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6322783, Length=138, Percent_Identity=46.3768115942029, Blast_Score=138, Evalue=3e-34,
Organism=Drosophila melanogaster, GI45549037, Length=135, Percent_Identity=46.6666666666667, Blast_Score=132, Evalue=6e-32,
Organism=Drosophila melanogaster, GI18860097, Length=133, Percent_Identity=35.3383458646617, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24645457, Length=137, Percent_Identity=30.6569343065693, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 16107; Mature: 16107

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTERTFSIIKPDVVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFF
CCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCCCEEH
VPLVEYMMSSPIVVSVLEKENAVKDYRTLIGTTNPETAAEGTIRKDFALSQRENSVHGSD
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
SIESANREIAYFFTNSEIFER
CHHCCCCEEEEEEECCHHHCC
>Mature Secondary Structure
MMTERTFSIIKPDVVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFF
CCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCCCEEH
VPLVEYMMSSPIVVSVLEKENAVKDYRTLIGTTNPETAAEGTIRKDFALSQRENSVHGSD
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
SIESANREIAYFFTNSEIFER
CHHCCCCEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA